Microglia morphotyping in the adult mouse CNS using hierarchical clustering on principal components reveals regional heterogeneity but no sexual dimorphism

Authors: Weering, Hilmar R. J., Nijboer, Tjalling W., Brummer, Maaike L., Boddeke, Erik W. G. M., Eggen, Bart J. L.

Source: Glia. 71(10):2356-2371

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189958384.0x000001&indx=1&recIds=ETOCvdc_100189958384.0x000001

Characterizing microglial gene expression in a model of secondary progressive multiple sclerosis

Authors: Vainchtein, Ilia D., Alsema, Astrid M., Dubbelaar, Marissa L., Grit, Corien, Vinet, Jonathan, Weering, Hilmar R. J., Al‐Izki, Sarah, Biagini, Giuseppe, Brouwer, Nieske, Amor, Sandra, Baker, David, Eggen, Bart J. L., Boddeke, Erik W. G. M., Kooistra, Susanne M.

Source: Glia. 71(3):588-601

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188279006.0x000001&indx=1&recIds=ETOCvdc_100188279006.0x000001

An emerging role for microglia in stress‐effects on memory

Authors: Sanguino‐Gómez, Jeniffer, Buurstede, Jacobus C., Abiega, Oihane, Fitzsimons, Carlos P., Lucassen, Paul J., Eggen, Bart J. L., Lesuis, Sylvie L., Meijer, Onno C., Krugers, Harm J.

Source: European journal of neuroscience. 55(9-10):2491-2518

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100162716468.0x000001&indx=1&recIds=ETOCvdc_100162716468.0x000001

Microglia regulate myelin clearance and cholesterol metabolism after demyelination via interferon regulatory factor 5: Microglia regulate myelin clearance...: A. Montilla et al.

Authors: Montilla, Alejandro, Zabala, Alazne, Calvo, Ibai, Bosch-Juan, Marina, Tomé-Velasco, Irene, Mata, Paloma, Koster, Mirjam, Sierra, Amanda, Kooistra, Susanne M., Soria, Federico N., Eggen, Bart J. L., Fresnedo, Olatz, Fernández, José Andrés, Tepavcevic, Vanja, Matute, Carlos, Domercq, María

Source: Cellular & Molecular Life Sciences; 3/26/2025, Vol. 82 Issue 1, p1-21, 21p

WDR49‐Positive Astrocytes Mark Severity of Neurodegeneration in Frontotemporal Lobar Degeneration and Alzheimer's Disease.

Authors: Rajicic, Ana, Giannini, Lucia A. A., Gerrits, Emma, van Buuren, Renee, Melhem, Shamiram, Slotman, Johan A., Rozemuller, Annemieke J. M., Eggen, Bart J. L., van Swieten, John C., Seelaar, Harro

Source: Glia; May2025, Vol. 73 Issue 5, p948-968, 21p

Exploring reported genes of microglia RNA‐sequencing data: Uses and considerations

Authors: Wageningen, Thecla A., Gerrits, Emma, Palacin i Bonson, Sara, Huitinga, Inge, Eggen, Bart J. L., Dam, Anne‐Marie

Source: Glia. 69(12):2933-2946

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131853595.0x000001&indx=1&recIds=ETOCvdc_100131853595.0x000001

Regionally diverse astrocyte subtypes and their heterogeneous response to EAE

Authors: Borggrewe, Malte, Grit, Corien, Vainchtein, Ilia D., Brouwer, Nieske, Wesseling, Evelyn M., Laman, Jon D., Eggen, Bart J. L., Kooistra, Susanne M., Boddeke, Erik W. G. M.

Source: Glia. 69(5):1140-1154

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116439297.0x000001&indx=1&recIds=ETOCvdc_100116439297.0x000001

The effects of postmortem delay on mouse and human microglia gene expression

Authors: Heng, Yang, Dubbelaar, Marissa L., Marie, Suely K. N., Boddeke, Erik W. G. M., Eggen, Bart J. L.

Source: Glia. 69(4):1053-1060

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114716047.0x000001&indx=1&recIds=ETOCvdc_100114716047.0x000001

Type I interferon‐activated microglia are critical for neuromyelitis optica pathology

Authors: Wlodarczyk, Agnieszka, Khorooshi, Reza, Marczynska, Joanna, Holtman, Inge R., Burton, Mark, Jensen, Kirstine Nolling, Blaabjerg, Morten, Meyer, Morten, Thomassen, Mads, Eggen, Bart J. L., Asgari, Nasrin, Owens, Trevor

Source: Glia. 69(4):943-953

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114715992.0x000001&indx=1&recIds=ETOCvdc_100114715992.0x000001

Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement

Authors: Zhang, Xiaoming, Heng, Yang, Kooistra, Susanne M., Weering, Hilmar R. J., Brummer, Maaike L., Gerrits, Emma, Wesseling, Evelyn M., Brouwer, Nieske, Nijboer, Tjalling W., Dubbelaar, Marissa L., Boddeke, Erik W. G. M., Eggen, Bart J. L.

Source: Glia. 69(3):729-745

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112553929.0x000001&indx=1&recIds=ETOCvdc_100112553929.0x000001

Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease

Authors: Rosenzweig, Neta, Kleemann, Kilian L., Rust, Thomas, Carpenter, Madison, Grucci, Madeline, Aronchik, Michael, Brouwer, Nieske, Valenbreder, Isabel, Cooper-Hohn, Joya, Iyer, Malvika, Krishnan, Rajesh K., Sivanathan, Kisha N., Brandão, Wesley, Yahya, Taha, Durao, Ana, Yin, Zhuoran, Chadarevian, Jean Paul, Properzi, Michael J., Nowarski, Roni, Davtyan, Hayk, Weiner, Howard L., Blurton-Jones, Mathew, Yang, Hyun-Sik, Eggen, Bart J. L., Sperling, Reisa A., Butovsky, Oleg

Source: Nature Medicine; October 2024, Vol. 30 Issue: 10 p2990-3003, 14p

Transcriptional profiling of microglia; current state of the art and future perspectives

Authors: Gerrits, Emma, Heng, Yang, Boddeke, Erik W. G. M., Eggen, Bart J. L.

Source: Glia. 68(4):740-755

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107740985.0x000001&indx=1&recIds=ETOCvdc_100107740985.0x000001

Targeted Diet Modification Reduces Multiple Sclerosis—like Disease in Adult Marmoset Monkeys from an Outbred Colony

Authors: Kap, Yolanda S., Bus-Spoor, Carien, van Driel, Nikki, Dubbelaar, Marissa L., Grit, Corien, Kooistra, Susanne M., Fagrouch, Zahra C., Verschoor, Ernst J., Bauer, Jan, Eggen, Bart J. L.

Source: Journal of immunology. 201(11):3229-3243

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN618238567&indx=1&recIds=ETOCRN618238567

Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing

Authors: Mekkes, Nienke J., Groot, Minke, Hoekstra, Eric, de Boer, Alyse, Dagkesamanskaia, Ekaterina, Bouwman, Sander, Wehrens, Sophie M. T., Herbert, Megan K., Wever, Dennis D., Rozemuller, Annemieke, Eggen, Bart J. L., Huitinga, Inge, Holtman, Inge R.

Source: Nature Medicine; April 2024, Vol. 30 Issue: 4 p1143-1153, 11p

Single-Nucleus RNA-Seq Characterizes the Cell Types Along the Neuronal Lineage in the Adult Human Subependymal Zone and Reveals Reduced Oligodendrocyte Progenitor Abundance with Age.

Authors: Puvogel, Sofía, Alsema, Astrid, North, Hayley F., Webster, Maree J., Weickert, Cynthia Shannon, Eggen, Bart J. L.

Source: eNeuro; Mar2024, Vol. 11 Issue 3, p1-19, 19p

Early amyloid‐induced changes in microglia gene expression in male APP/PS1 mice.

Authors: Oshima, Takuya, Kater, Mandy S. J., Huffels, Christiaan F. M., Wesseling, Evelyn M., Middeldorp, Jinte, Hol, Elly M., Verheijen, Mark H. G., Smit, August B., Boddeke, Erik W. G. M., Eggen, Bart J. L.

Source: Journal of Neuroscience Research; Mar2024, Vol. 102 Issue 3, p1-14, 14p

Glioblastoma and its treatment are associated with extensive accelerated brain aging.

Authors: Ainslie, Anna P., Klaver, Myrthe, Voshart, Daniëlle C., Gerrits, Emma, den Dunnen, Wilfred F. A., Eggen, Bart J. L., Bergink, Steven, Barazzuol, Lara

Source: Aging Cell; Mar2024, Vol. 23 Issue 3, p1-14, 14p

Subject Terms: METHYLGUANINE, DNA damage, GLIOBLASTOMA multiforme, AGING, BRAIN tumors, ALZHEIMER'S disease, TAU proteins

Isolation of Microglia and Immune Infiltrates from Mouse and Primate Central Nervous System

Authors: Galatro, Thais F., Vainchtein, Ilia D., Brouwer, Nieske, Boddeke, Erik W. G. M., Eggen, Bart J. L.

Source: Methods in molecular biology. 1559:333-342

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Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein

Authors: Jagessar, S. Anwar, Holtman, Inge R., Hofman, Sam, Morandi, Elena, Heijmans, Nicole, Laman, Jon D., Gran, Bruno, Faber, Bart W., van Kasteren, Sander I., Eggen, Bart J. L.

Source: Journal of immunology. 197(4):1074-1088

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN607444223&indx=1&recIds=ETOCRN607444223

Microglia morphotyping in the adult mouse CNS using hierarchical clustering on principal components reveals regional heterogeneity but no sexual dimorphism.

Authors: van Weering, Hilmar R. J., Nijboer, Tjalling W., Brummer, Maaike L., Boddeke, Erik W. G. M., Eggen, Bart J. L.

Source: Glia; Oct2023, Vol. 71 Issue 10, p2356-2371, 16p