Effects of PDE10A inhibitor MK-8189 in people with an acute episode of schizophrenia: A randomized proof-of-concept clinical trial

Authors: Mukai, Yuki, Lupinacci, Robert, Marder, Stephen, Snow-adami, Linda, Voss, Tiffini, Smith, Sean M., Egan, Michael F.

Source: In Schizophrenia Research August 2024 270:37-43

Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease

Authors: Wessels, Alette M., Lines, Christopher, Stern, Robert A., Kost, James, Voss, Tiffini, Mozley, Lyn Harper, Furtek, Christine, Mukai, Yuki, Aisen, Paul S., Cummings, Jeffrey L., Tariot, Pierre N., Vellas, Bruno, Dupre, Nicole, Randolph, Christopher, Michelson, David, Andersen, Scott W., Shering, Craig, Sims, John R., Egan, Michael F.

Source: Alzheimer's & dementia. 16(11):1483-1492

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128886914.0x000001&indx=1&recIds=ETOCvdc_100128886914.0x000001

Variation in DISC1 Affects Hippocampal Structure and Function and Increases Risk for Schizophrenia

Authors: Callicott, Joseph H., Straub, Richard E., Pezawas, Lukas, Egan, Michael F., Mattay, Venkata S., Hariri, Ahmad R., Verchinski, Beth A., Meyer-Lindenberg, Andreas, Balkissoon, Rishi, Kolachana, Bhaskar, Goldberg, Terry E., Weinberger, Daniel R., Scolnick, Edward M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2005 Jun . 102(24), 8627-8632.

Access URL: https://www.jstor.org/stable/3375763

Variation in GRM3 Affects Cognition, Prefrontal Glutamate, and Risk for Schizophrenia

Authors: Egan, Michael F., Straub, Richard E., Goldberg, Terry E., Yakub, Imtiaz, Callicott, Joseph H., Hariri, Ahmad R., Mattay, Venkata S., Bertolino, Alessandro, Hyde, Thomas M., Shannon-Weickert, Cynthia, Akil, Mayada, Crook, Jeremy, Vakkalanka, Radha Krishna, Balkissoon, Rishi, Gibbs, Richard A., Kleinman, Joel E., Weinberger, Daniel R., Mishkin, Mortimer

Source: Proceedings of the National Academy of Sciences of the United States of America, 2004 Aug . 101(34), 12604-12609.

Access URL: https://www.jstor.org/stable/3373030

Catechol O-Methyltransferase val158-met Genotype and Individual Variation in the Brain Response to Amphetamine

Authors: Mattay, Venkata S., Goldberg, Terry E., Fera, Francesco, Hariri, Ahmad R., Tessitore, Alessandro, Egan, Michael F., Kolachana, Bhaskar, Callicott, Joseph H., Weinberger, Daniel R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 May . 100(10), 6186-6191.

Access URL: https://www.jstor.org/stable/3147563

Serotonin Transporter Genetic Variation and the Response of the Human Amygdala

Authors: Hariri, Ahmad R., Mattay, Venkata S., Tessitore, Alessandro, Kolachana, Bhaskar, Fera, Francesco, Goldman, David, Egan, Michael F., Weinberger, Daniel R.

Source: Science, 2002 Jul . 297(5580), 400-403.

Access URL: https://www.jstor.org/stable/3077181

Effect of COMT Val 108/158 Met Genotype on Frontal Lobe Function and Risk for Schizophrenia

Authors: Egan, Michael F., Goldberg, Terry E., Kolachana, Bhaskar S., Callicott, Joseph H., Mazzanti, Chiara M., Straub, Richard E., Goldman, David, Weinberger, Daniel R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2001 Jun 01. 98(12), 6917-6922.

Access URL: https://www.jstor.org/stable/3055912

A multinational study distinguishing Alzheimer's and healthy patients using cerebrospinal fluid tau/Aβ42 cutoff with concordance to amyloid positron emission tomography imaging

Authors: Mo, Yi, Stromswold, Julie, Wilson, Kimberly, Holder, Daniel, Sur, Cyrille, Laterza, Omar, Savage, Mary J., Struyk, Arie, Scheltens, Philip, Teunissen, Charlotte E., Burke, James, Macaulay, S. Lance, Bråthen, Geir, Sando, Sigrid Botne, White, Linda R., Weiss, Christy, Cowes, Arturo, Bush, Michele M., DeSilva, Ganga, Darby, David G., Rainey-Smith, Stephanie R., Surls, Jackie, Sagini, Eileen, Tanen, Michael, Altman, Amy, Luthman, Johan, Egan, Michael F.

Source: In Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 2017 6:201-209

Longitudinal investigation for enhancing Down Syndrome Research (LIFE‐DSR) Study: Tau PET and CSF sub‐studies

Authors: Hendrix, James A., Britton, Angela, Christian, Bradley T., Ledesma, Duvia Lara, Egan, Michael F., Feldman, Howard, Hendrix, Suzanne B., Herring, W. Joseph, Kennedy, Matthew E., Nicodemus‐Johnson, Jessie, Revta, Carolyn, Struyk, Arie, Sur, Cyrille, Mobley, William C.

Source: Alzheimer's & dementia. 17(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138849474.0x000001&indx=1&recIds=ETOCvdc_100138849474.0x000001

Dopaminergic therapy removal differentially effects learning in schizophrenia and Parkinson’s disease

Authors: Weickert, Thomas W., Mattay, Venkata S., Das, Saumitra, Bigelow, Llewellyn B., Apud, Jose A., Egan, Michael F., Weinberger, Daniel R., Goldberg, Terry E.

Source: In Schizophrenia Research September 2013 149(1-3):162-166

Magnitude of Impact of Executive Functioning and IQ on Episodic Memory in Schizophrenia

Authors: Kopald, Brandon E., Mirra, Kathryn M., Egan, Michael F., Weinberger, Daniel R., Goldberg, Terry E.

Source: In Biological Psychiatry 15 March 2012 71(6):545-551

The Evolutionarily Conserved G Protein-Coupled Receptor SREB2/GPR85 Influences Brain Size, Behavior, and Vulnerability to Schizophrenia

Authors: Matsumoto, Mitsuyuki, Straub, Richard E., Marenco, Stefano, Nicodemus, Kristin K., Matsumoto, Shun-ichiro, Fujikawa, Akihiko, Miyoshi, Sosuke, Shobo, Miwako, Takahashi, Shinji, Yarimizu, Junko, Yuri, Masatoshi, Hiramoto, Masashi, Morita, Shuji, Yokota, Hiroyuki, Sasayama, Takeshi, Terai, Kazuhiro, Yoshino, Masayasu, Miyake, Akira, Callicott, Joseph H., Egan, Michael F., Meyer-Lindenberg, Andreas, Kempf, Lucas, Honea, Robyn, Vakkalanka, Radha Krishna, Takasaki, Jun, Kamohara, Masazumi, Soga, Takatoshi, Hiyama, Hideki, Ishii, Hiroyuki, Matsuo, Ayako, Nishimura, Shintaro, Matsuoka, Nobuya, Kobori, Masato, Matsushime, Hitoshi, Katoh, Masao, Furuichi, Kiyoshi, Weinberger, Daniel R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2008 Apr . 105(16), 6133-6138.

Access URL: https://www.jstor.org/stable/25461751

Epistasis between Catechol-O-Methyltransferase and Type II Metabotropic Glutamate Receptor 3 Genes on Working Memory Brain Function

Authors: Tan, Hao-Yang, Chen, Qiang, Sust, Steven, Buckholtz, Joshua W., Meyers, John D., Egan, Michael F., Mattay, Venkata S., Meyer-Lindenberg, Andreas, Weinberger, Daniel R., Callicott, Joseph H.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2007 Jul . 104(30), 12536-12541.

Access URL: https://www.jstor.org/stable/25436335

Further analyses of the safety of verubecestat in the phase 3 EPOCH trial of mild-to-moderate Alzheimer's disease

Authors: Egan, Michael F., Mukai, Yuki, Voss, Tiffini, Kost, James, Stone, Julie, Furtek, Christine, Mahoney, Erin, Cummings, Jeffrey L., Tariot, Pierre N., Aisen, Paul S., Vellas, Bruno, Lines, Christopher, Michelson, David

Source: Alzheimer's research & therapy. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130360003.0x000001&indx=1&recIds=ETOCvdc_100130360003.0x000001

Relative Risk of Probabilistic Category Learning Deficits in Patients with Schizophrenia and Their Siblings

Authors: Weickert, Thomas W., Goldberg, Terry E., Egan, Michael F., Apud, Jose A., Meeter, Martijn, Myers, Catherine E., Gluck, Mark A., Weinberger, Daniel R.

Source: In Biological Psychiatry 2010 67(10):948-955

Progression from Prodromal Alzheimer's Disease to Mild Alzheimer's Disease Dementia in the Verubecestat APECS Study: Adjudicating Diagnostic Transitions.

Authors: Voss, Tiffini, Kost, James, Mercer, Swati Pal, Furtek, Christine, Randolph, Christopher, Lines, Christopher, Egan, Michael F., Cummings, Jeffrey L.

Source: Journal of Alzheimer's Disease; 2023, Vol. 92 Issue 1, p341-348, 8p

Subject Terms: ALZHEIMER'S disease, ATTITUDE change (Psychology), DEMENTIA, VASCULAR dementia

False positives in imaging genetics

Authors: Meyer-Lindenberg, Andreas, Nicodemus, Kristin K., Egan, Michael F., Callicott, Joseph H., Mattay, Venkata, Weinberger, Daniel R.

Source: In NeuroImage 1 April 2008 40(2):655-661

Verbal and visual memory: Characterizing the clinical and intermediate phenotype in schizophrenia

Authors: Skelley, Shayna L., Goldberg, Terry E., Egan, Michael F., Weinberger, Daniel R., Gold, James M.

Source: In Schizophrenia Research 2008 105(1):78-85

BDNF Val 66Met polymorphism significantly affects d′ in verbal recognition memory at short and long delays

Authors: Goldberg, Terry E., Iudicello, Jennifer, Russo, Christine, Elvevåg, Brita, Straub, Richard, Egan, Michael F., Weinberger, Daniel R.

Source: In Biological Psychology 2008 77(1):20-24

Set-Shifting Ability and Schizophrenia: A Marker of Clinical Illness or an Intermediate Phenotype?

Authors: Ceaser, Alan E., Goldberg, Terry E., Egan, Michael F., McMahon, Robert P., Weinberger, Daniel R., Gold, James M.

Source: In Biological Psychiatry 2008 64(9):782-788