Aripiprazole dose associations with metabolic adverse effect: Results from a longitudinal study

Authors: Piras, Marianna, Popovic, Iris, Ranjbar, Setareh, Grosu, Claire, Laaboub, Nermine, Sentissi, Othman, Lakhal, Mohamed H., Gamma, Franziska, Plessen, Kerstin J., von Gunten, Armin, Conus, Philippe, Eap, Chin B.

Source: In Schizophrenia Research August 2024 270:403-409

Exploring low clozapine C/D ratios, inverted clozapine-norclozapine ratios and undetectable concentrations as measures of non-adherence in clozapine patients: A literature review and a case series of 17 patients from 3 studies

Authors: Ruan, Can-Jun, Olmos, Ismael, Ricciardi, Carina, Schoretsanitis, Georgios, Vincent, Philippe D., Anıl Yağcıoğlu, A. Elif, Eap, Chin B., Baptista, Trino, Clark, Scott R., Fernandez-Egea, Emilio, Kim, Se Hyun, Lane, Hsien-Yuan, Leung, Jonathan, Maroñas Amigo, Olalla, Motuca, Mariano, Every-Palmer, Susanna, Procyshyn, Ric M., Rohde, Christopher, Suhas, Satish, Schulte, Peter F.J., Spina, Edoardo, Takeuchi, Hiroyoshi, Verdoux, Hélène, Correll, Christoph U., Molden, Espen, De Las Cuevas, Carlos, de Leon, Jose

Source: In Schizophrenia Research June 2024 268:293-301

Clozapine ultrarapid metabolism during weak induction probably exists but requires careful diagnosis. A literature review, five new cases and a proposed definition

Authors: Schoretsanitis, Georgios, Anıl Yağcıoğlu, A. Elif, Ruan, Can-Jun, Eap, Chin B., Molden, Espen, Baptista, Trino, Clark, Scott R., Fernandez-Egea, Emilio, Kim, Se Hyun, Lane, Hsien-Yuan, Leung, Jonathan, Maroñas Amigo, Olalla, Motuca, Mariano, Olmos, Ismael, Every-Palmer, Susanna, Procyshyn, Ric M., Rohde, Christopher, Satish, Suhas, Schulte, Peter F.J., Spina, Edoardo, Takeuchi, Hiroyoshi, Verdoux, Hélène, Correll, Christoph U., de Leon, Jose

Source: In Schizophrenia Research June 2024 268:302-307

Guía internacional para una dosificación más segura de la clozapina en adultos mediante el uso de 6 titulaciones personalizadas de dosis basados en la etnicidad, la proteína C reactiva y los niveles de clozapina

Alternate Title: An international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, CRP, and clozapine levels (English)

Authors: de Leon, Jose, Schoretsanitis, Georgios, Smith, Robert L., Molden, Espen, Solismaa, Anssi, Seppälä, Niko, Kopeček, Miloslav, Švancer, Patrik, Olmos, Ismael, Ricciardi, Carina, Iglesias-Garcia, Celso, Iglesias-Alonso, Ana, Spina, Edoardo, Ruan, Can-Jun, Wang, Chuan-Yue, Wang, Gang, Tang, Yi-Lang, Lin, Shih-Ku, Lane, Hsien-Yuan, Kim, Yong Sik, Kim, Se Hyun, Rajkumar, Anto P., González-Esquivel, Dinora F., Jung-Cook, Helgi, Baptista, Trino, Rohde, Christopher, Nielsen, Jimmi, Verdoux, Hélène, Quiles, Clelia, Sanz, Emilio J., De las Cuevas, Carlos, Cohen, Dan, Schulte, Peter F.J., Ertuğrul, Aygün, Anıl Yağcıoğlu, A. Elif, Chopra, Nitin, McCollum, Betsy, Shelton, Charles, Cotes, Robert O., Kaithi, Arun R., Kane, John M., Farooq, Saeed, Ng, Chee H., Bilbily, John, Hiemke, Christoph, López-Jaramillo, Carlos, McGrane, Ian, Lana, Fernando, Eap, Chin B., Arrojo-Romero, Manuel, Rădulescu, Flavian Ştefan, Seifritz, Erich, Every-Palmer, Susanna, Bousman, Chad A., Bebawi, Emmanuel, Bhattacharya, Rahul, Kelly, Deanna L., Otsuka, Yuji, Lazary, Judit, Torres, Rafael, Yecora, Agustin, Motuca, Mariano, Chan, Sherry Kit Wa, Zolezzi, Monica, Ouanes, Sami, De Berardis, Domenico, Grover, Sandeep, Procyshyn, Ric M., Adebayo, Richard A., Kirilochev, Oleg O., Soloviev, Andrey, Fountoulakis, Konstantinos N., Wilkowska, Alina, Cubała, Wiesław Jerzy, Ayub, Muhammad, Silva, Alzira, Bonelli, Raphael M., Villagrán-Moreno, José María, Crespo-Facorro, Benedicto, Temmingh, Henk, Decloedt, Eric, Pedro, Maria Rosel, Takeuchi, Hiroyoshi, Tsukahara, Masaru, Gründer, Gerhard, Sagud, Marina, Celofiga, Andreja, Ignjatovic Ristic, Dragana, Ortiz, Bruno Bertolucci, Elkis, Helio, Pacheco Palha, António José, Llerena, Adrián, Fernandez-Egea, Emilio, Siskind, Dan, Weizman, Abraham, Masmoudi, Rim, Mohd Saffian, Shamin, Leung, Jonathan G., Buckley, Peter F., Marder, Stephen R., Citrome, Leslie, Freudenreich, Oliver, Correll, Christoph U., Müller, Daniel J.

Source: In Psiquiatria Biologica September-December 2023 30(3)

Clinical predictors of antipsychotic treatment resistance: Development and internal validation of a prognostic prediction model by the STRATA-G consortium

Authors: Smart, Sophie E., Agbedjro, Deborah, Pardiñas, Antonio F., Ajnakina, Olesya, Alameda, Luis, Andreassen, Ole A., Barnes, Thomas R.E., Berardi, Domenico, Camporesi, Sara, Cleusix, Martine, Conus, Philippe, Crespo-Facorro, Benedicto, D'Andrea, Giuseppe, Demjaha, Arsime, Di Forti, Marta, Do, Kim, Doody, Gillian, Eap, Chin B., Ferchiou, Aziz, Guidi, Lorenzo, Homman, Lina, Jenni, Raoul, Joyce, Eileen, Kassoumeri, Laura, Lastrina, Ornella, Melle, Ingrid, Morgan, Craig, O'Neill, Francis A., Pignon, Baptiste, Restellini, Romeo, Richard, Jean-Romain, Simonsen, Carmen, Španiel, Filip, Szöke, Andrei, Tarricone, Ilaria, Tortelli, Andrea, Üçok, Alp, Vázquez-Bourgon, Javier, Murray, Robin M., Walters, James T.R., Stahl, Daniel, MacCabe, James H.

Source: In Schizophrenia Research December 2022 250:1-9

The psychosis metabolic risk calculator (PsyMetRiC) for young people with psychosis: International external validation and site-specific recalibration in two independent European samples

Authors: Perry, Benjamin I., Vandenberghe, Frederik, Garrido-Torres, Nathalia, Osimo, Emanuele F., Piras, Marianna, Vazquez-Bourgon, Javier, Upthegrove, Rachel, Grosu, Claire, De La Foz, Victor Ortiz-Garcia, Jones, Peter B., Laaboub, Nermine, Ruiz-Veguilla, Miguel, Stochl, Jan, Dubath, Celine, Canal-Rivero, Manuel, Mallikarjun, Pavan, Delacrétaz, Aurélie, Ansermot, Nicolas, Fernandez-Egea, Emilio, Crettol, Severine, Gamma, Franziska, Plessen, Kerstin J., Conus, Philippe, Khandaker, Golam M., Murray, Graham K., Eap, Chin B., Crespo-Facorro, Benedicto

Source: In The Lancet Regional Health - Europe November 2022 22

Olanzapine‐associated dose‐dependent alterations for weight and metabolic parameters in a prospective cohort

Authors: Schoretsanitis, Georgios, Dubath, Céline, Grosu, Claire, Piras, Marianna, Laaboub, Nermine, Ranjbar, Setareh, Ansermot, Nicolas, Crettol, Séverine, Vandenberghe, Frederik, Gamma, Franziska, Gunten, Armin, Plessen, Kerstin Jessica, Seifritz, Erich, Conus, Philippe, Eap, Chin B.

Source: Basic & clinical pharmacology & toxicology. 130(4):531-541

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100143438080.0x000001&indx=1&recIds=ETOCvdc_100143438080.0x000001

Psychotropic Drug Prescription in Children and Adolescents: Approved Medications in European Countries and the United States

Authors: Smogur, Michal, Onesanu, Alice, Plessen, Kerstin Jessica, Eap, Chin B., Ansermot, Nicolas

Source: Journal of child and adolescent psychopharmacology. 32(2):80-88

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144281514.0x000001&indx=1&recIds=ETOCvdc_100144281514.0x000001

Investigating the Relations Between Caffeine-Derived Metabolites and Plasma Lipids in 2 Population-Based Studies

Authors: Petrovic, Dusan, Pruijm, Menno, Ponte, Belén, Dhayat, Nasser A., Ackermann, Daniel, Ehret, Georg, Ansermot, Nicolas, Vogt, Bruno, Martin, Pierre-Yves, Stringhini, Silvia, Estoppey-Younès, Sandrine, Thijs, Lutgarde, Zhang, Zhenyu, Melgarejo, Jesus D., Eap, Chin B., Staessen, Jan A., Bochud, Murielle, Guessous, Idris

Source: In Mayo Clinic Proceedings December 2021 96(12):3071-3085

Metabolomic alteration induced by psychotropic drugs: Short‐term metabolite profile as a predictor of weight gain evolution

Authors: Lenski, Marie, Sidibé, Jonathan, Gholam, Mehdi, Hennart, Benjamin, Dubath, Céline, Augsburger, Marc, Gunten, Armin, Conus, Philippe, Allorge, Delphine, Thomas, Aurelien, Eap, Chin B.

Source: Clinical and translational science. 14(6):2544-2555

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100137339918.0x000001&indx=1&recIds=ETOCvdc_100137339918.0x000001

Valproate is associated with early decrease of high‐density lipoprotein cholesterol levels in the psychiatric population

Authors: Delacrétaz, Aurélie, Glatard, Anaïs, Dubath, Céline, Gholam, Mehdi, Gamma, Franziska, Gunten, Armin, Conus, Philippe, Eap, Chin B.

Source: Basic & clinical pharmacology & toxicology. 129(1):26-35

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122572092.0x000001&indx=1&recIds=ETOCvdc_100122572092.0x000001

Therapeutic Drug Monitoring of Olanzapine: Effects of Clinical Factors on Plasma Concentrations in Psychiatric Patients.

Authors: Ansermot, Nicolas, Vathanarasa, Harish, Ranjbar, Setareh, Gholam, Mehdi, Crettol, Séverine, Vandenberghe, Frederik, Gamma, Franziska, Plessen, Kerstin Jessica, von Gunten, Armin, Conus, Philippe, Eap, Chin B.

Source: Therapeutic Drug Monitoring; Dec2024, Vol. 46 Issue 6, p828-836, 9p

Psychotropic-induced weight gain and telomere length: results from a one-year longitudinal study and a large population-based cohort.

Authors: Piras, Marianna, Lin, Jue, Sadler, Marie Catherine, Ranjbar, Setareh, Grosu, Claire, Laaboub, Nermine, Preisig, Martin, Gamma, Franziska, Plessen, Kerstin Jessica, von Gunten, Armin, Conus, Philippe, Kutalik, Zoltan, Eap, Chin B.

Source: Translational Psychiatry; 11/15/2024, Vol. 14 Issue 1, p1-10, 10p

A population pharmacokinetic model for sertraline in women during the perinatal period—A contribution from the ConcePTION project.

Authors: Monfort, Anaëlle, Cardoso, Evelina, Eap, Chin B., Ansermot, Nicolas, Crettol, Severine, Fischer Fumeaux, Céline J., Graz, Myriam Bickle, Harari, Mathilde Morisod, Weisskopf, Etienne, Gandia, Peggy, Allegaert, Karel, Annaert, Pieter, Nordeng, Hedvig, Hascoët, Jean‐Michel, Claris, Olivier, Epiney, Manuella, Ferreira, Ema, Leclair, Grégoire, Csajka, Chantal, Panchaud, Alice

Source: British Journal of Clinical Pharmacology; Nov2024, Vol. 90 Issue 11, p2849-2860, 12p

Subject Terms: FAT content of milk, CORD blood, BREAST milk, PERINATAL period, PREGNANT women, BREASTFEEDING

Pharmacokinetics and Pharmacodynamics of Inhaled Nicotine Salt and Free-Base Using an E-cigarette: A Randomized Crossover Study.

Authors: Christen, Samuel E, Hermann, Laura, Bekka, Elias, Vonwyl, Celina, Hammann, Felix, van der Velpen, Vera, Eap, Chin B, Benowitz, Neal L, Haschke, Manuel, Liakoni, Evangelia

Source: Nicotine & Tobacco Research; Oct2024, Vol. 26 Issue 10, p1313-1321, 9p

Subject Terms: COTININE, ELECTRONIC cigarettes, NICOTINE, SMOKING, SMOKING cessation

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The effect of perazine on the CYP2D6 and CYP2C19 phenotypes as measured by the dextromethorphan and mephenytoin tests in psychiatric patients

Authors: Baumann, Pierre, Eap, Chin B., Gastpar, Markus

Source: Basic & clinical pharmacology & toxicology. 126(5):444-447

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108644231.0x000001&indx=1&recIds=ETOCvdc_100108644231.0x000001

A population pharmacokinetic model for escitalopram and its major metabolite in depressive patients during the perinatal period: Prediction of infant drug exposure through breast milk

Authors: Weisskopf, Etienne, Guidi, Monia, Fischer, Céline J., Bickle Graz, Myriam, Beaufils, Etienne, Nguyen, Kim An, Morisod Harari, Mathilde, Rouiller, Sylvie, Rothenburger, Sophie, Gaucherand, Pascal, Kassai‐Koupai, Behrouz, Borradori Tolsa, Cristina, Epiney, Manuella, Tolsa, Jean‐François, Vial, Yvan, Hascoët, Jean‐Michel, Claris, Olivier, Eap, Chin B, Panchaud, Alice, Csajka, Chantal

Source: British journal of clinical pharmacology. 86(8):1642-1653

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107398276.0x000001&indx=1&recIds=ETOCvdc_100107398276.0x000001

A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants

Authors: Kanders, Sofia H., Pisanu, Claudia, Bandstein, Marcus, Jonsson, Jörgen, Castelao, Enrique, Pistis, Giorgio, Gholam‐Rezaee, Mehdi, Eap, Chin B., Preisig, Martin, Schiöth, Helgi B., Mwinyi, Jessica

Source: Drug development research. 81(1):102-113

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103466545.0x000001&indx=1&recIds=ETOCvdc_100103466545.0x000001