Enterovirus D68 infection in cotton rats results in systemic inflammation with detectable viremia associated with extracellular vesicle and neurologic disease.

Authors: Blanco, Jorge C. G.¹ (AUTHOR) j.blanco@sigmovir.com, Sylla, Fatoumata Y. D.¹ (AUTHOR), Granados, Sandra¹ (AUTHOR), Noghero, Alessio² (AUTHOR), Boukhvalova, Marina S.¹ (AUTHOR), Kajon, Adriana E.² (AUTHOR)

Source: Scientific Reports. 2/22/2025, Vol. 15 Issue 1, p1-18. 18p.

Subject Terms: *MEDICAL sciences, *ENTEROVIRUS diseases, *EXTRACELLULAR vesicles, *NEUROLOGICAL disorders, *MEDICAL microbiology

Epidemiological, Biological, and Clinical Characteristics of Central Nervous System Enterovirus Infections Among Hospitalized Patients at Ibn Sina University Hospital Center in Rabat: Case Study Report (A Series of 19 Cases).

Authors: Echiguer, Chemsdine^1,2 (AUTHOR) chemsdine.echiguer@um5s.net.ma, El Amin, Ghizlane^1,2 (AUTHOR), Zouaki, Amal^1,2 (AUTHOR), Zirar, Jalila^1,2 (AUTHOR), Seffar, Myriam^1,2 (AUTHOR), Mahraoui, Chafiq^1,3 (AUTHOR), Kabbaj, Hakima^1,2 (AUTHOR), Jabir, Majid (AUTHOR)

Source: Advances in Virology. 11/21/2024, Vol. 2024, p1-6. 6p.

Subject Terms: *ENTEROVIRUS diseases, *CHILD patients, *SYMPTOMS, *CENTRAL nervous system, *CEREBROSPINAL fluid examination, *FEVER, CENTRAL nervous system infections

From the "One-Molecule, One-Target, One-Disease" Concept towards Looking for Multi-Target Therapeutics for Treating Non-Polio Enterovirus (NPEV) Infections.

Authors: Roux, Hugo¹ (AUTHOR) hugo.roux@univ-amu.fr, Touret, Franck² (AUTHOR) franck.touret@univ-amu.fr, Rathelot, Pascal¹ (AUTHOR) pascal.rathelot@univ-amu.fr, Vanelle, Patrice¹ (AUTHOR) patrice.vanelle@univ-amu.fr, Roche, Manon¹ (AUTHOR) patrice.vanelle@univ-amu.fr

Source: Pharmaceuticals (14248247). Sep2024, Vol. 17 Issue 9, p1218. 41p.

Subject Terms: *ENTEROVIRUS diseases, *DRUG design, *COXSACKIEVIRUSES, *DRUG efficacy, *RHINOVIRUSES

Epidemiology of childhood enterovirus infections in Hangzhou, China, 2019–2023.

Authors: Sun, Jian¹ (AUTHOR), Guo, Yajun² (AUTHOR) guoyj@zju.edu.cn, Li, Lin³ (AUTHOR), Li, Yaling⁴ (AUTHOR), Zhou, Hangyu^5,6 (AUTHOR), Li, We² (AUTHOR)

Source: Virology Journal. 8/26/2024, Vol. 21 Issue 1, p1-10. 10p.

Subject Terms: *HAND, foot & mouth disease, *ENTEROVIRUS diseases, *CHILDREN'S hospitals, *COVID-19 pandemic, *RESPIRATORY diseases

Genetic Diversity of Human Enterovirus in Kazakhstan, during 2022.

Authors: Kamalova, Dinara^1,2 (AUTHOR), Akhmetova, Assel¹ (AUTHOR), Amirgazin, Asylulan¹ (AUTHOR), Sytnik, Igor¹ (AUTHOR), Rudenko, Viktoriya³ (AUTHOR), Yessimkhanova, Gulzhan³ (AUTHOR), Bayesheva, Dinagul³ (AUTHOR), Yegorov, Sergey^1,4 (AUTHOR), Shevtsov, Alexander¹ (AUTHOR) ncbshevtsov@gmail.com, Callaway, Todd R. (AUTHOR)

Source: International Journal of Microbiology. 8/26/2024, Vol. 2024, p1-15. 15p.

Subject Terms: *ENTEROVIRUS diseases, *HUMAN genetic variation, *VIRAL proteins, *CEREBROSPINAL fluid, *COXSACKIEVIRUSES

Real-Time Enterovirus D68 Outbreak Detection through Hospital Surveillance of Severe Acute Respiratory Infection, Senegal, 2023.

Authors: Jallow, Mamadou Malado¹, Mendy, Marie Pedapa¹, Barry, Mamadou Aliou¹, Diagne, Moussa Moise¹, Sagne, Samba Niang¹, Tall, Fatime², Diouf, Jean Baptisse Niokhor³, Ndiaye, Ndiendé Koba¹, Kiori, Davy¹, Sy, Sara¹, Goudiaby, Déborah¹, Loucoubar, Cheikh¹, Fall, Gamou¹, Kadjo, Hervé⁴, Bessaud, Maël⁵, Dia, Ndongo¹ ndia@pasteur.sn

Source: Emerging Infectious Diseases. Aug2024, Vol. 30 Issue 8, p1687-1691. 5p.

Subject Terms: *RESPIRATORY infections, *ENTEROVIRUS diseases, *ACUTE flaccid paralysis, *HOSPITALS

Geographic Terms: DAKAR (Senegal), SENEGAL

Neonatal Enteroviral Meningoencephalitis: Clinical and Paraclinical Characteristics of a Nosocomial Outbreak in Colombia.

Authors: Martín, Delia Edith Theurel¹ (AUTHOR) delia.theurel@gmail.com, Socarras, Jorge Luis Alvarado² (AUTHOR)

Source: Journal of Clinical Neonatology. Jul-Sep2024, Vol. 13 Issue 3, p119-123. 5p.

Subject Terms: *ENTEROVIRUS diseases, *LIVER failure, *C-reactive protein, *CEREBROSPINAL fluid, *MENINGOENCEPHALITIS

Enterovirus A71 and coxsackievirus A6 circulation in England, UK, 2006–2017: A mathematical modelling study using cross-sectional seroprevalence data.

Authors: Kamau, Everlyn¹, everlyn.kamau@ucsf.edu, Lambert, Ben², Allen, David J.³, Celma, Cristina⁴, Beard, Stuart⁴, Harvala, Heli^5,6, Simmonds, Peter¹, Grassly, Nicholas C.⁷, Pons-Salort, Margarita⁷, everlyn.kamau@ucsf.edu

Source: PLoS Pathogens; 11/20/2024, Vol. 20 Issue 11, p1-21, 21p

WHO's Health Emergencies Programme: acute emergencies monthly summary -- January and February 2024.

Alternate Title: Programme OMS de gestion des situations d'urgence sanitaire: résumé mensuel des situations d'urgence aiguë -- janvier et février 2024.

Source: Weekly Epidemiological Record; 4/5/2024, Vol. 99 Issue 14, p163-168, 6p

Investigation of the Correlation between Enterovirus Infection and the Climate Factor Complex Including the Ping-Year Factor and El Niño-Southern Oscillation in Taiwan.

Authors: Yu, Hsueh-Wen^1,2 (AUTHOR) b9905026@cgmh.org.tw, Kuan, Chia-Hsuan^1,2 (AUTHOR) gh70106@gmail.com, Tseng, Liang-Wei^1,2 (AUTHOR) frank.tseng.sr@gmail.com, Chen, Hsing-Yu³ (AUTHOR) 8705016@cgmh.org.tw, Tsai, Meg-Yen⁴ (AUTHOR) spiritfly903@gmail.com, Chen, Yu-Sheng^1,2,5 (AUTHOR) cusp01@cgmh.org.tw

Source: Viruses (1999-4915). Mar024, Vol. 16 Issue 3, p471. 14p.

Subject Terms: *ENTEROVIRUS diseases, *POISSON regression, EL Nino, LA Nina

Geographic Terms: TAIWAN

Emerging Enterovirus A71 Subgenogroup B5 Causing Severe Hand, Foot, and Mouth Disease, Vietnam, 2023.

Authors: Nguyen Van Vinh Chau¹, Tang Chi Thuong¹, Nguyen Thanh Hung², Nguyen Thi Thu Hong³, Du Tuan Quy², Tran Ba Thien³, Cao Minh Hiep², Ngo Ngoc Quang Minh², Truong Huu Khanh², Do Duong Kim Han³, Truong Hoang Chau Truc³, Nguyen Thi Han Ny³, Le Kim Thanh³, Lam Anh Nguyet³, Cao Thu Thuy³, Le Nguyen Truc Nhu³, Pham Van Quang^2,4, Phung Nguyen^2,5, The Nguyen⁵, Phan Tu Qui⁶

Source: Emerging Infectious Diseases. Feb2024, Vol. 30 Issue 2, p363-367. 5p.

Subject Terms: *ENTEROVIRUS diseases, *FOOT & mouth disease

Geographic Terms: VIETNAM

The Repurposing of Cellular Proteins during Enterovirus A71 Infection.

Authors: Abedeera, Sudeshi M.¹ (AUTHOR) sudeshi.abedeera@pennmedicine.upenn.edu, Davila-Calderon, Jesse² (AUTHOR) jxd519@case.edu, Haddad, Christina² (AUTHOR) christinahaddad621@gmail.com, Henry, Barrington¹ (AUTHOR) barrington.henry@pennmedicine.upenn.edu, King, Josephine² (AUTHOR) jak362@case.edu, Penumutchu, Srinivasa¹ (AUTHOR) srinivasa.penumutchu@pennmedicine.upenn.edu, Tolbert, Blanton S.^1,3 (AUTHOR) blanton.tolbert@pennmedicine.upenn.edu

Source: Viruses (1999-4915). Jan2024, Vol. 16 Issue 1, p75. 26p.

Subject Terms: *ENTEROVIRUS diseases, *VIRAL genes, *RNA synthesis, *VIRAL genomes, *DRUG target, *PROTEINS

Company/Entity: UNITED States. Food & Drug Administration

Production of a genetically encoded biosensor for evaluating enterovirus 71 3C protease inhibitors.

Authors: Ye, Jiankai¹ (AUTHOR), Zhang, Rui¹ (AUTHOR), Liu, Xiaoping¹ (AUTHOR), Chen, Yunyu¹ (AUTHOR) chenyunyu1984@163.com

Source: Preparative Biochemistry & Biotechnology. Feb2025, p1-6. 6p. 3 Illustrations.

Subject Terms: *FLUORESCENCE resonance energy transfer, *ENTEROVIRUS diseases, *FLUORESCENT proteins, *RAPID tooling, *PEPTIDES

Synergistic combination of orally available safe-in-man pleconaril, AG7404, and mindeudesivir inhibits enterovirus infections in human cell and organoid cultures.

Authors: Ravlo, Erlend¹ (AUTHOR), Ianevski, Aleksandr¹ (AUTHOR), Schjølberg, Jørn-Ove^1,2 (AUTHOR), Solvang, Vanessa¹ (AUTHOR), Dumaru, Rabina¹ (AUTHOR), Lysvand, Hilde¹ (AUTHOR), Hankinson, Jacqueline³ (AUTHOR), Vähä-Koskela, Markus^4,5,6 (AUTHOR), Vainionpää, Sanna^5,6,7 (AUTHOR), Varhe, Anni^5,6,7 (AUTHOR), Seppänen, Hanna^5,6,7 (AUTHOR), Smura, Teemu^8,9 (AUTHOR), Wang, Xin¹⁰ (AUTHOR), Wang, Yining¹⁰ (AUTHOR), Li, Pengfei¹⁰ (AUTHOR), Pan, Qiuwei¹⁰ (AUTHOR), Dahl-Jorgensen, Knut¹¹ (AUTHOR), Krogvold, Lars¹² (AUTHOR), Kamyshnyi, Oleksandr¹³ (AUTHOR), Nilsen, Hans-Johnny Schjelderup¹⁴ (AUTHOR)

Source: Cellular & Molecular Life Sciences. 1/23/2025, Vol. 82 Issue 1, p1-13. 13p.

Subject Terms: *MEDICAL sciences, *ENTEROVIRUS diseases, *HUMAN cell culture, *ORGANS (Anatomy), *MEDICAL microbiology

The neurological damage caused by enterovirus 71 infection is associated with hsa_circ_0069335/miR-29b/PMP22 pathway.

Authors: Guangming Liu¹, Danping Zhu¹, Kuan Feng¹, Hongxia Peng¹ huangli7525@163.com, Sida Yang¹, Li Huang¹ lipeiqing@gwcmc.org, Peiqing Li¹ annie_129@126.com

Source: Journal of Virology. Jan2025, Vol. 99 Issue 1, p1-17. 17p.

Subject Terms: *HAND, foot & mouth disease, *ENTEROVIRUS diseases, *SCHWANN cells, *MYELIN sheath, *CHILD mortality

Molecular epidemiology and phylodynamic analysis of enterovirus 71 in Beijing, China, 2009–2019.

Authors: Li, Jie¹ (AUTHOR), Liang, Zhichao² (AUTHOR), Huo, Da² (AUTHOR), Yang, Yang² (AUTHOR), Li, Renqing² (AUTHOR), Jia, Lei² (AUTHOR), Wang, Xiaoli³ (AUTHOR), Huang, Chun¹ (AUTHOR) huangch@bjcdc.org, Wang, Quanyi² (AUTHOR) bjcdcxm@126.com

Source: Virology Journal. 11/3/2023, Vol. 20 Issue 1, p1-9. 9p.

Subject Terms: *FOOT & mouth disease, *ENTEROVIRUS diseases, *MOLECULAR epidemiology, *TERTIARY structure, *GENETIC variation

Geographic Terms: BEIJING (China), CHINA

Enterovirus-Rhinovirus-Induced Acute Respiratory Distress Syndrome in Adults: A Case Report and Short Literature Review.

Authors: Avgoustou, Eirini¹ (AUTHOR), Spyridaki, Aikaterini² (AUTHOR), Pothitos, Giorgos¹ (AUTHOR), Papadopoulos, Antonios³ (AUTHOR), Kois, Spyridon¹ (AUTHOR), Vassilara, Foula¹ (AUTHOR)

Source: Case Reports in Infectious Diseases. 11/3/2023, p1-6. 6p.

Subject Terms: *ADULT respiratory distress syndrome, *ENTEROVIRUS diseases, *COMMON cold, *POLYMERASE chain reaction, *NON-coding RNA

Duration of Enterovirus D68 RNA Shedding in the Upper Respiratory Tract and Transmission among Household Contacts, Colorado, USA.

Authors: Hai Nguyen-Tran¹, hai.nguyen-tran@childrenscolorado.org, Thompson, Careese², Butler, Molly², Miller, Kristen R.¹, Pyle, Laura¹, Jung, Sarah², Rogers, Shannon³, Fei Fan Ng, Terry³, Routh, Janell³, Dominguez, Samuel R.¹, Messacar, Kevin¹

Source: Emerging Infectious Diseases; Nov2023, Vol. 29 Issue 11, p2315-2324, 10p

Emerging trends and insights in acute flaccid myelitis: a comprehensive review of neurologic manifestations.

Authors: Singh, Baljinder¹ (AUTHOR), Arora, Sanchit² (AUTHOR), Sandhu, Navjot³ (AUTHOR)

Source: Infectious Diseases. Oct2023, Vol. 55 Issue 10, p653-663. 11p. 1 Color Photograph, 1 Chart.

Subject Terms: *ENTEROVIRUS diseases, *REVERSE transcriptase polymerase chain reaction, *MYELITIS, *PARAPLEGIA, *PUBLIC health administration, *NEUROLOGICAL disorders

Temporal regulation of MDA5 inactivation by Caspase-3 dependent cleavage of 14-3-3η.

Authors: Chan, Yun-Jui¹, Liu, Nien-Tzu¹, Hsin, Fu¹, Lu, Jia-Ying², Lin, Jing-Yi², Liu, Helene Minyi¹, mliu@ntu.edu.tw

Source: PLoS Pathogens; 6/6/2024, Vol. 20 Issue 6, p1-21, 21p