Vps34-orchestrated lipid signaling processes regulate the transitional heterogeneity and functional adaptation of effector regulatory T cells.

Authors: Norton, Erienne G.^1,2, Chapman, Nicole M.¹, Shi, Hao¹, Meng, Xiaoxi¹, Huang, Hongling¹, KC, Anil¹, Rankin, Sherri¹, Saravia, Jordy¹, Yuan, Sujing¹, Hu, Haoran¹, Vogel, Peter³, Chi, Hongbo^1,2, hongbo.chi@stjude.org

Source: PLoS Biology; 4/11/2025, Vol. 23 Issue 4, p1-47, 47p

HOPS/CORVET tethering complexes are critical for endocytosis and protein trafficking to invasion related organelles in malaria parasites.

Authors: Mesén-Ramírez, Joëlle Paolo^1,2,3, Fuchs, Gwendolin^1,2,3, Burmester, Jonas^1,2,3, Farias, Guilherme B.^1,2,3, Alape-Flores, Ana María⁴, Singla, Shamit^5,6, Alder, Arne^1,2,3, Cubillán-Marín, José², Castro-Peña, Carolina², Lemcke, Sarah^1,3, Sondermann, Holger^1,7,8, Prado, Mónica⁴, Spielmann, Tobias², Wilson, Danny^1,2,5,6, Gilberger, Tim-Wolf^1,2,3, gilberger@bnitm.de

Source: PLoS Pathogens; 4/8/2025, Vol. 21 Issue 4, p1-34, 34p

The CLIC/GEEC pathway regulates particle uptake and formation of the virus-containing compartment (VCC) in HIV-1-infected macrophages.

Authors: Candor, Kathleen^1,2, Ding, Lingmei², Balchand, Sai², Hammonds, Jason E.², Spearman, Paul², paul.spearman@cchmc.org

Source: PLoS Pathogens; 3/11/2025, Vol. 21 Issue 3, p1-31, 31p

Evaluating the Effects of Perinatal Exposures to BPSIP on Hepatic Cholesterol Metabolism in Female and Male Offspring ICR Mice.

Authors: Qi Wang^1,2 wangwinqi@163.com, Shulin Gao², Baoqiang Chen², Jiadi Zhao¹, Wenyong Li², Lijun Wu¹ ljw@ipp.ac.cn

Source: Environmental Health Perspectives. Sep2024, Vol. 132 Issue 9, p097011-1-097011-17. 17p.

Subject Terms: *Biochemistry, *Animal experimentation, RNA analysis, RNA metabolism, Lipid metabolism, Protein metabolism, Cholesterol metabolism, Estrogen replacement therapy, Biological models, In vitro studies, HDL cholesterol, Endocytosis, Maternal exposure, Prenatal exposure delayed effects, Research funding, Liquid chromatography-mass spectrometry, Fatty liver, Computer software, T-test (Statistics), Data analysis, Sex distribution, Sulfones, Polymerase chain reaction, Fisher exact test, Body weight, In vivo studies, Descriptive statistics, Fluorescent antibody technique, LDL cholesterol, Mice, Gene expression, Immunohistochemistry, Estrogen receptors, Experimental design, Bioinformatics, Messenger RNA, Genes, Gene expression profiling, Cholesterol, Western immunoblotting, One-way analysis of variance, Statistics, Metabolism, Liver, Data analysis software, Phenotypes, Histology, Precipitin tests, Immunoblotting, Cultures (Biology), Sequence analysis, Disease risk factors

Folic acid-mediated hollow Mn3O4 nanocomposites for in vivo MRI/FLI monitoring the metastasis of gastric cancer.

Authors: Yang, Zhihua¹ (AUTHOR), Wang, Chenying² (AUTHOR), Du, Shangting¹ (AUTHOR), Ma, Qin¹ (AUTHOR), Wang, Wei¹ (AUTHOR), liu, Changhu¹ (AUTHOR), Zhan, Yonghua² (AUTHOR), Zhan, Wenhua¹ (AUTHOR) zhanwhgood@163.com

Source: BioMedical Engineering OnLine. 6/10/2024, Vol. 23 Issue 1, p1-17. 17p.

Subject Terms: *STOMACH cancer, *ENDOCYTOSIS, *METASTASIS, *MAGNETIC resonance imaging, *NANOCOMPOSITE materials, *CARCINOMA in situ, *FOLIC acid

Increased endocytosis rate and enhanced lysosomal pathway of silica-coated superparamagnetic nanoparticles into M-HeLa cells compared with cultured primary motor neurons.

Authors: Sibgatullina, Guzel¹ (AUTHOR), Ramazanova, Iliza¹ (AUTHOR), Salnikov, Vadim¹ (AUTHOR), Stepanov, Alexey² (AUTHOR), Voloshina, Alexandra² (AUTHOR), Sapunova, Anastasiia² (AUTHOR), Mustafina, Asiya² (AUTHOR), Petrov, Konstantin^1,2 (AUTHOR), Samigullin, Dmitry^1,3 (AUTHOR) samid75@mail.ru

Source: Histochemistry & Cell Biology. Jun2024, Vol. 161 Issue 6, p507-519. 13p.

Subject Terms: *MOTOR neurons, *ENDOCYTOSIS, *CELL culture, *MAGNETIC resonance imaging, *TRANSMISSION electron microscopy, *NANOPARTICLES

A Dual Strategy—In Vitro and In Silico—To Evaluate Human Antitetanus mAbs Addressing Their Potential Protective Action on TeNT Endocytosis in Primary Rat Neuronal Cells.

Authors: Lima, Cauã Pacheco^1,2 (AUTHOR) caua.lima@usp.br, Barreiros, Gabriela Massaro^1,2 (AUTHOR) gabriela.barreiros@usp.br, Oliveira, Adriele Silva Alves¹ (AUTHOR) adriele.soliveira@butantan.gov.br, de Souza, Marcelo Medina³ (AUTHOR) marcelo.souza@butantan.gov.br, Manieri, Tania Maria^1,4 (AUTHOR) tania.manieri@butantan.gov.br, Moro, Ana Maria^1,4 (AUTHOR) tania.manieri@butantan.gov.br

Source: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p5788. 16p.

Subject Terms: *ENDOCYTOSIS, *SYNAPTIC vesicles, *BOOSTER vaccines, *MOLECULAR docking, *IMMUNOGLOBULINS, DEVELOPING countries

Structural Variants and Implicated Processes Associated with Familial Tourette Syndrome.

Authors: Fichna, Jakub P.¹ (AUTHOR) c.zekanowski@imdik.pan.pl, Chiliński, Mateusz^2,3,4 (AUTHOR) m.chilinski@cent.uw.edu.pl, Halder, Anup Kumar^2,3 (AUTHOR) a.halder@cent.uw.edu.pl, Cięszczyk, Paweł⁵ (AUTHOR) pawel.cieszczyk@awf.gda.pl, Plewczynski, Dariusz^2,3 (AUTHOR) d.plewczynski@cent.uw.edu.pl, Żekanowski, Cezary^1,5 (AUTHOR), Janik, Piotr⁶ (AUTHOR) piotr.janik@wum.edu.pl

Source: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p5758. 13p.

Subject Terms: *TOURETTE syndrome, *ENDOCYTOSIS, *WHOLE genome sequencing, *NEURAL transmission, *AUDITORY perception, *SENSORY perception, *SYNAPTIC vesicles

Endocytosis of Charged Electrically Nano Drugs Described by Boltzmann Equation

Authors: Nieto-Chaupis, Huber

Source: 2024 IEEE 22nd Student Conference on Research and Development (SCOReD) Research and Development (SCOReD), 2024 IEEE 22nd Student Conference on. :450-454 Dec, 2024

Relation: 2024 IEEE 22nd Student Conference on Research and Development (SCOReD)

LRP1 is the cell‐surface endocytosis receptor for vaspin in adipocytes.

Authors: Tindall, Catherine A.^1,2 (AUTHOR), Möhlis, Kevin¹ (AUTHOR), Rapöhn, Inka¹ (AUTHOR), Dommel, Sebastian^1,2 (AUTHOR), Riedl, Veronika² (AUTHOR), Schneekönig, Michael¹ (AUTHOR), Höfling, Corinna³ (AUTHOR), Roßner, Steffen³ (AUTHOR), Stichel, Jan² (AUTHOR), Beck‐Sickinger, Annette G.² (AUTHOR), Weiner, Juliane⁴ (AUTHOR), Heiker, John T.^1,2 (AUTHOR) john.heiker@helmholtz-munich.de

Source: FEBS Journal. May2024, Vol. 291 Issue 10, p2134-2154. 21p.

Subject Terms: *FAT cells, *ENDOCYTOSIS, *ADIPOSE tissues, *ADIPOGENESIS, *CELL membranes, *INSULIN resistance, *NITRIC-oxide synthases, *INSULIN

Mutational Analysis of RIP Type I Dianthin-30 Suggests a Role for Arg24 in Endocytosis.

Authors: Schlaak, Louisa¹ (AUTHOR) l.schlaak@fu-berlin.de, Weise, Christoph² (AUTHOR) chris.weise@biochemie.fu-berlin.de, Kuropka, Benno² (AUTHOR) kuropka@zedat.fu-berlin.de, Weng, Alexander¹ (AUTHOR) alexander.weng@fu-berlin.de

Source: Toxins. May2024, Vol. 16 Issue 5, p219. 23p.

Subject Terms: *ENDOCYTOSIS, *RIBOSOMES, *AMINO acid residues, *CYTOTOXINS, *CARNATIONS, *SAPONINS

Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease.

Authors: Eteleeb, Abdallah M.^1,2 (AUTHOR), Novotny, Brenna C.¹ (AUTHOR), Tarraga, Carolina Soriano¹ (AUTHOR), Sohn, Christopher¹ (AUTHOR), Dhungel, Eliza³ (AUTHOR), Brase, Logan¹ (AUTHOR), Nallapu, Aasritha¹ (AUTHOR), Buss, Jared¹ (AUTHOR), Farias, Fabiana^1,4 (AUTHOR), Bergmann, Kristy^1,4 (AUTHOR), Bradley, Joseph^1,4 (AUTHOR), Norton, Joanne^1,4 (AUTHOR), Gentsch, Jen^1,4 (AUTHOR), Wang, Fengxian^1,4 (AUTHOR), Davis, Albert A.^5,6 (AUTHOR), Morris, John C.^2,5,6 (AUTHOR), Karch, Celeste M.^1,2,4,6 (AUTHOR), Perrin, Richard J.^2,5,6,7 (AUTHOR), Benitez, Bruno A.⁸ (AUTHOR), Harari, Oscar^1,2,6 (AUTHOR) oscar.harari@usumc.edu

Source: PLoS Biology. 4/30/2024, Vol. 22 Issue 4, p1-45. 45p.

Subject Terms: *ALZHEIMER'S disease, *ENDOCYTOSIS, *MULTIOMICS, *ALZHEIMER'S patients, *DATA integration, *HETEROGENEITY

Inhibition of Autophagy Alters Intracellular Transport of APP Resulting in Increased APP Processing.

Authors: Mayer, Johanna¹ (AUTHOR), Boeck, Dominik^1,2 (AUTHOR), Werner, Michelle¹ (AUTHOR), Frankenhauser, Daniela³ (AUTHOR), Geley, Stephan³ (AUTHOR), Farhan, Hesso³ (AUTHOR), Shimozawa, Makoto¹ (AUTHOR), Nilsson, Per¹ (AUTHOR) per.et.nilsson@ki.se

Source: Traffic. Apr2024, Vol. 25 Issue 4, p1-23. 23p.

Subject Terms: *ENDOCYTOSIS, *AMYLOID beta-protein precursor, *AUTOPHAGY, *ENDOPLASMIC reticulum, *ALZHEIMER'S disease, *CELL imaging

Human Herpesvirus Epstein-Barr (EBV) and Its Porcine Homologs Unveil the Conserved Mechanism of Receptor Endocytosis: New Insights Into Viral Immune Evasion and Antiviral Therapy Potential?

Alternate Title: Humani herpesvirus Epstein-Barr (EBV) in njegovi prašičji homologi razkrivajo ohranjeni mehanizem receptorske endocitoze: nov vpogled v virusno izmikanje imunskemu sistemu in potencialne protivirusne terapije?

Authors: Kubale, Valentina¹ valentina.kubaledvojmoc@vf.uni-lj.si

Source: Slovenian Veterinary Research / Slovenski Veterinarski Zbornik. 2024, Vol. 61 Issue 2, p81-84. 4p.

Subject Terms: *ENDOCYTOSIS, *HUMAN beings, *EPSTEIN-Barr virus

The CHD family chromatin remodeling enzyme, Kismet, promotes both clathrin-mediated and activity-dependent bulk endocytosis.

Authors: Hendricks, Emily L.¹ (AUTHOR), Liebl, Faith L. W.¹ (AUTHOR) fliebl@siue.edu

Source: PLoS ONE. 3/21/2024, Vol. 19 Issue 3, p1-28. 28p.

Subject Terms: *COATED vesicles, *ENDOCYTOSIS, *CHROMATIN-remodeling complexes, *AUTISM spectrum disorders, *SYNAPTIC vesicles, *DNA helicases, *CHROMATIN

AMPA Receptors Endocytosis Inhibition Attenuates Cognition Deficit Via c-Fos/BDNF Signaling in Amyloid β Neurotoxicity.

Authors: Eyvani, Kimia^1,2,3, Letafatkar, Negin^1,2,3, Babaei, Parvin^1,2,3 p_babaei@gums.ac.ir

Source: Experimental Aging Research. May/Jun2025, Vol. 51 Issue 3, p303-315. 13p.

Subject Terms: *ENDOCYTOSIS, *SYNDROMES, *NEUROPROTECTIVE agents, *NEUROTOXICOLOGY, *RESEARCH funding, *DATA analysis, *ALZHEIMER'S disease, *CELLULAR signal transduction, *DESCRIPTIVE statistics, *RATS, *INJECTIONS, *COGNITION disorders, *BRAIN-derived neurotrophic factor, *ANIMAL experimentation, *WESTERN immunoblotting, *ANIMAL behavior, *ANALYSIS of variance, *STATISTICS, *ONE-way analysis of variance, *HIPPOCAMPUS (Brain), *DATA analysis software, *SHORT-term memory, *CELL receptors, *BIOMARKERS, *AMYLOID beta-protein precursor

Arrestin‐independent internalization of the GLP‐1 receptor is facilitated by a GRK, clathrin, and caveolae‐dependent mechanism.

Authors: Moo, Ee Von¹ (AUTHOR) ee.von.moo@sund.ku.dk, Møller, Thor Christian¹ (AUTHOR), Sørensen, Frederikke Astrid¹ (AUTHOR), Inoue, Asuka^2,3 (AUTHOR), Bräuner‐Osborne, Hans¹ (AUTHOR)

Source: FEBS Journal. Apr2025, Vol. 292 Issue 7, p1675-1695. 21p.

Subject Terms: *ENDOCYTOSIS, *CLATHRIN, *CAVEOLAE, *ARRESTINS, *GLUCAGON-like peptide-1 agonists, *TYPE 2 diabetes, *PANCREATIC beta cells, *G protein-coupled receptor kinases

TAT-1, a phosphatidylserine flippase, affects molting and regulates membrane trafficking in the epidermis of Caenorhabditis elegans.

Authors: Milne, Shae M¹, Edeen, Philip T¹, Fay, David S¹

Source: Genetics. Mar2025, Vol. 229 Issue 3, p1-16. 16p.

Subject Terms: *IN vitro studies, *ENDOCYTOSIS, *CYTOLOGY, *PHOSPHOLIPIDS, *CELL membranes, *RESEARCH funding, *CARRIER proteins, *PROTEIN kinases, *BIOLOGICAL transport, *NEMATODES, *HUMAN growth, *DESCRIPTIVE statistics, *EPIDERMIS, *ANIMAL experimentation, *CYTOPLASM, *CAENORHABDITIS elegans, *GENETIC mutation, *MOLECULAR chaperones, *GENETIC techniques, *ALLELES, *MEMBRANE proteins, *GENETICS

Detection of Kelch13 and Coronin Genes in Colpodella sp. ATCC 50594.

Authors: Sam-Yellowe, Tobili Y.¹ (AUTHOR) t.sam-yellowe@csuohio.edu, Roy, Antara^1,2 (AUTHOR), Nims, Trinity¹ (AUTHOR), Qaderi, Sona^1,2 (AUTHOR), Peterson, John W.² (AUTHOR)

Source: Parasitologia. Mar2025, Vol. 5 Issue 1, p5. 15p.

Subject Terms: *GENES, *ENDOCYTOSIS, *PROTOZOA, *MICROFILAMENT proteins, *NUTRIENT uptake

Transmission of peripheral blood α-synuclein fibrils exacerbates synucleinopathy and neurodegeneration in Parkinson's disease by endothelial Lag3 endocytosis.

Authors: Duan, Qingrui^1,2,3, Zhang, Qingxi^1,2, Jiang, ShuoLin^1,2,3, Nie, Kun^1,2, Feng, Shujun^1,2, Qiu, Yihui^1,2, He, Peikun^1,2, Xing, Yuxuan^1,2, Liu, Jiaxuan^1,2, Ma, Guixian^1,2, Zhang, Yuhu^1,2, Gao, Yuyuan^1,2, gaoyuyuan@gdph.org.cn, Wang, Lijuan^1,2,3, wanglijuan@gdph.org.cn

Source: American Journal of Physiology: Cell Physiology; Mar2025, Vol. 328 Issue 3, pC836-C855, 20p