Redox-Active Molecules as Therapeutic Agents

Contributors: Fernandes, Ana Sofia

Subject Terms: non-small cell lung cancer, cisplatin, apurinic/apyrimidinic endonuclease 1, E3330, cytotoxicity, apoptosis, migration, invasion, oxidative stress, sildenafil, DNA damage, systemic sclerosis, bioactivity-based assays, cyanidin, metabolomics, Rubus genus, (poly)phenols, yeast-based discovery platform, withanolide, breast cancer, mitochondrial reactive oxygen species, peroxiredoxin 3, pro-oxidant therapy, thiostrepton, GSH, Cysteamine, N-acetyl cysteine, KEAP1, NRF2, ATF4, adipose-derived mesenchymal stem cell, amniotic membrane-derived mesenchymal stem cell, antioxidants, assisted reproductive technology, conditioned medium, embryo, in vitro culture, in vitro fertilization, BAPN, cell invasion, EMT, lysyl-oxidase, lysyl-oxidase like 2, metastases, inhibitors, doxorubicin, chemoresistance, redox signaling, nuclear factor erythroid 2-related factor 2 (Nrf2), cancer therapy, hydrogen sulfide, reactive oxygen species, H2S donors, cardiorenal syndrome, thiosulfate, selenium-enriched Enterococcus faecium, selenium-enriched Streptococcus thermophilus, antioxidant capacity, glutathione reductase, glutathione peroxidase, CD IGS rats, lactic acid bacteria, verbascoside, hypercholesterolemia, prostate cancer, curcumin, carnosic acid, cell cycle, OxPhos, SGK1, Research and information: general, Biology, life sciences

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/87539
https://mdpi.com/books/pdfview/book/5737

Impact of the APE1 Redox Function Inhibitor E3330 in Non-Small Cell Lung Cancer Cells Exposed to Cisplatin: Increased Cytotoxicity and Impairment of Cell Migration and Invasion

Authors: Rita Manguinhas, Ana S. Fernandes, João G. Costa, Nuno Saraiva, Sérgio P. Camões, Nuno Gil, Rafael Rosell, Matilde Castro, Joana P. Miranda, Nuno G. Oliveira

Source: Antioxidants, Vol 9, Iss 6, p 550 (2020)

Subject Terms: non-small cell lung cancer, cisplatin, apurinic/apyrimidinic endonuclease 1, E3330, cytotoxicity, apoptosis, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/9/6/550; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/46f20bc6e47f419a90aa09ab839afbab

Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization

Authors: Y. Li, X. Liu, T. Zhou, M.R. Kelley, P. Edwards, H. Gao, X. Qiao

Source: Redox Biology, Vol 2, Iss C, Pp 485-494 (2014)

Subject Terms: APE1/Ref-1redox function, E3330, Oxidative stress, Retinal pigment epithelial cell, Transcription factor, Age-related macular degeneration., Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221323171400038X; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/eb00df3e36ae443c87cb01a9f3a434f8

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