Mechanobiological cues to bone cells during early metastasis drive later osteolysis: A computational mechanoregulation framework prediction

Authors: Verbruggen, Anneke S.K. ^a, McCarthy, Elan C. ^b, Dwyer, Roisin M. ^b, McNamara, Laoise M. ^{a, ⁎}

Source: In Mechanobiology in Medicine March 2025 3(1)

Nanoscale structure detection and monitoring of tumour growth with optical coherence tomography

Authors: Das, Nandan, Sergey, Alexandrov, Zhou, Yi, Gilligan, Katie E., Dwyer, Róisín M, Leahy, Martin

Subject Terms: Physics - Medical Physics

Access URL: http://arxiv.org/abs/2005.13318

Temporal and spatial changes in bone mineral content and mechanical properties during breast-cancer bone metastases

Authors: Verbruggen, Anneke S.K., McCarthy, Elan C., Dwyer, Roisin M., McNamara, Laoise M.

Source: In Bone Reports December 2022 17

Implementing subtype‐specific pre‐clinical models of breast cancer to study pre‐treatment aspirin effects

Authors: Miller, Ian S., Khan, Sonja, Shiels, Liam P., Das, Sudipto, O' Farrell, Alice C., Connor, Kate, Lafferty, Adam, Moran, Bruce, Isella, Claudio, Loadman, Paul, Conroy, Emer, Cohrs, Susan, Schibli, Roger, Kerbel, Robert S., Gallagher, William M., Marangoni, Elisabetta, Bennett, Kathleen, O' Connor, Darran P., Dwyer, Róisín M., Byrne, Annette T.

Source: Cancer medicine. 11(20):3820-3836

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163054741.0x000001&indx=1&recIds=ETOCvdc_100163054741.0x000001

Evaluation of human adipose-derived stromal cell behaviour following exposure to Tamoxifen

Authors: Challapalli, Ritihaas Surya, Dwyer, Roisin M., McInerney, Niall, Kerin, Michael J., Lowery, Aoife J.

Source: In Tissue and Cell August 2022 77

Targeting stromal cell Syndecan‐2 reduces breast tumour growth, metastasis and limits immune evasion

Authors: Loftus, Paul G., Watson, Luke, Deedigan, Laura M., Camarillo‐Retamosa, Eva, Dwyer, Róisín M., O'Flynn, Lisa, Alagesan, Senthilkumar, Griffin, Matthew, O'Brien, Timothy, Kerin, Michael J., Elliman, Stephen J., Barkley, Laura R.

Source: International journal of cancer. 148(5):1245-1259

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112325746.0x000001&indx=1&recIds=ETOCvdc_100112325746.0x000001

Nanoscale structure detection and monitoring of tumour growth with optical coherence tomographyElectronic supplementary information (ESI) available: OCT schematic; nsOCT flowchart; maximum spatial period vs. depth video: healthy and tumour. See DOI: 10.1039/d0na00371a

Authors: Das, Nandan, Sergey, Alexandrov, Zhou, Yi, Gilligan, Katie E., Dwyer, Róisín M., Leahy, Martin

Source: Nanoscale advances. 2(7):2853-2858

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108998850.0x000001&indx=1&recIds=ETOCvdc_100108998850.0x000001

Characterization of nano sensitive sub-micron scale tissue-structural multifractality and its alteration in tumor progress
Dynamics and Fluctuations in Biomedical Photonics XVII

Authors: Das, Nandan, Alexandrov, Sergey, Dwyer, Róisín M., Saager, Rolf, Ghosh, Nirmalya, Leahy, Martin

Source: Proceedings of SPIE, the International Society for Optical Engineering. 11239:1123912-1123912-4

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN900017301&indx=1&recIds=ETOCCN900017301

Circulating MicroRNAs in Cancer

Authors: O Brien, Killian P., Ramphul, Eimear, Howard, Linda, Gallagher, William M., Malone, Carmel, Kerin, Michael J., Dwyer, Róisín M.

Source: Methods in molecular biology. 1509:123-140

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN608919282&indx=1&recIds=ETOCRN608919282

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

Authors: Logue, Susan E., McGrath, Eoghan P., Cleary, Patricia, Greene, Stephanie, Mnich, Katarzyna, Almanza, Aitor, Chevet, Eric, Dwyer, Róisín M., Oommen, Anup, Legembre, Patrick, Godey, Florence, Madden, Emma C., Leuzzi, Brian, Obacz, Joanna, Zeng, Qingping, Patterson, John B., Jäger, Richard, Gorman, Adrienne M., Samali, Afshin

Source: Nature communications. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129890204.0x000001&indx=1&recIds=ETOCvdc_100129890204.0x000001

Engineering Exosomes for Cancer Therapy.

Authors: Gilligan, Katie E.¹ K.GILLIGAN3@nuigalway.ie, Dwyer, Róisín M.¹ roisin.dwyer@nuigalway.ie

Source: International Journal of Molecular Sciences. Jun2017, Vol. 18 Issue 6, p1122. 12p. 2 Charts.

Subject Terms: *EXOSOMES, *CANCER treatment, *ELECTROPORATION, *LIPOFECTION, *TUMOR growth

Characterization of nanosensitive multifractality in submicron scale tissue morphology and its alteration in tumor progression (Erratum)

Authors: Das, Nandan, Alexandrov, Sergey, Gilligan, Katie E., Dwyer, Róisín M., Saager, Rolf B., Ghosh, Nirmalya, Leahy, Martin

Source: Journal of biomedical optics. 26(1):019805-019805

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189241371.0x000001&indx=1&recIds=ETOCvdc_100189241371.0x000001

A Preclinical Large Animal Model of Adenovirus-Mediated Expression of the Sodium–Iodide Symporter for Radioiodide Imaging and Therapy of Locally Recurrent Prostate Cancer

Authors: Dwyer, Roisin M., Schatz, Stephen M., Bergert, Elizabeth R., Myers, Rae M., Harvey, Mary E., Classic, Kelly L., Blanco, Michael C., Frisk, Craig S., Marler, Ronald J., Davis, Brian J., O'Connor, Michael K., Russell, Stephen J., Morris, John C.

Source: In Molecular Therapy November 2005 12(5):835-841

A comparative analysis of extracellular vesicles (EVs) from human and feline plasma.

Authors: Howard, Jane, Wynne, Kieran, Moldenhauer, Evelin, Clarke, Paul, Maguire, Ciaran, Bollard, Stephanie, Yin, Xiaofei, Brennan, Lorraine, Mooney, Louise, Fitzsimons, Stephen, Halasz, Melinda, Aluri, Ester Rani, Brougham, Dermot F., Kolch, Walter, Dwyer, Róisín M., Potter, Shirley, Kelly, Pamela, McCann, Amanda

Source: Scientific Reports; 6/27/2022, Vol. 12 Issue 1, p1-16, 16p

Subject Terms: EXTRACELLULAR vesicles, FIELD-flow fractionation, BIOLOGICAL transport, BIOMATERIALS, COMPARATIVE studies

Investigating the Potential and Pitfalls of EV-Encapsulated MicroRNAs as Circulating Biomarkers of Breast Cancer.

Authors: Moloney, Brian M., Gilligan, Katie E., Joyce, Doireann P., O’Neill, Clodagh P., O’Brien, Killian P., Khan, Sonja, Glynn, Claire L., Waldron, Ronan M., Maguire, Ciarán M., Holian, Emma, Naughton, Erin, Elhadi, Mohamed, Grealish, Andrea B., Malone, Carmel, McDermott, Emma, Dockery, Peter, Ritter, Thomas, Prina-Mello, Adriele, Kerin, Michael J., Dwyer, Róisín M.

Source: Cells (2073-4409); Jan2020, Vol. 9 Issue 1, p1-13, 14p

Subject Terms: BREAST cancer, EXTRACELLULAR vesicles, TRANSMISSION electron microscopy, BIOLOGICAL tags, WESTERN immunoblotting

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Impact of Mesenchymal Stem Cell secreted PAI-1 on colon cancer cell migration and proliferation

Authors: Hogan, Niamh M., Joyce, Myles R., Murphy, J. Mary, Barry, Frank P., O’Brien, Timothy, Kerin, Michael J., Dwyer, Roisin M.

Source: In Biochemical and Biophysical Research Communications 14 June 2013 435(4):574-579

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