Cellpose as a reliable method for single-cell segmentation of autofluorescence microscopy images

Authors: Jeremiah M. Riendeau, Amani A. Gillette, Emmanuel Contreras Guzman, Mario Costa Cruz, Aleksander Kralovec, Shirsa Udgata, Alexa Schmitz, Dustin A. Deming, Beth A. Cimini, Melissa C. Skala

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-11 (2025)

Subject Terms: Autofluorescence, Segmentation, Single-cell, Organoid, Deep-learning, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/b509388195d24143b70a83119f4be015

Impact of baseline culture conditions of cancer organoids when determining therapeutic response and tumor heterogeneity

Authors: Rebecca A. DeStefanis, Jeremy D. Kratz, Autumn M. Olson, Aishwarya Sunil, Alyssa K. DeZeeuw, Amani A. Gillette, Gioia C. Sha, Katherine A. Johnson, Cheri A. Pasch, Linda Clipson, Melissa C. Skala, Dustin A. Deming

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0850400bc08146908046414b05f6fcca

Case report: Radiographic complete response of radiation-induced glioblastoma to front-line radiotherapy: A report and molecular characterization of two unique cases

Authors: Patrick T. Grogan, Jeffrey J. Helgager, Dustin A. Deming, Steven P. Howard, Robert B. Jenkins, H. Ian Robins

Source: Frontiers in Neurology, Vol 14 (2023)

Subject Terms: radiation-induced glioma (RIG), complete response (CR), radiation, molecular sequencing, chromosomal microarray, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2023.1099424/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/fd5e022e89164767842b930277235940

Multi‐ancestral origin of intestinal tumors: Impact on growth, progression, and drug efficacy

Authors: Alyssa A. Leystra, Brock J. Gilsdorf, Amanda M. Wisinger, Elise R. Warda, Shanna Wiegand, Christopher D. Zahm, Kristina A. Matkowskyj, Dustin A. Deming, Naghma Khan, Quincy Rosemarie, Chelsie K. Sievers, Alexander R. Schwartz, Dawn M. Albrecht, Linda Clipson, Hasan Mukhtar, Michael A. Newton, Richard B. Halberg

Source: Cancer Reports, Vol 5, Iss 2, Pp n/a-n/a (2022)

Subject Terms: colorectal cancer, drug efficacy, heterotypic tumors with a multi‐ancestral origin/architecture, invasiveness, tumor origin, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2573-8348

Access URL: https://doaj.org/article/8da5b0c5b0914ae6be7061afed01adcb

Metabolic Heterogeneity in Patient Tumor-Derived Organoids by Primary Site and Drug Treatment

Authors: Joe T. Sharick, Christine M. Walsh, Carley M. Sprackling, Cheri A. Pasch, Dan L. Pham, Karla Esbona, Alka Choudhary, Rebeca Garcia-Valera, Mark E. Burkard, Stephanie M. McGregor, Kristina A. Matkowskyj, Alexander A. Parikh, Ingrid M. Meszoely, Mark C. Kelley, Susan Tsai, Dustin A. Deming, Melissa C. Skala

Source: Frontiers in Oncology, Vol 10 (2020)

Subject Terms: pancreatic cancer, breast cancer, organoid, optical metabolic imaging, heterogeneity, cellular metabolism, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2020.00553/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/14fa7f59dd114a328e1ac580d07887b7

Molecular Evolution of a Glioblastoma Controlled With Tumor Treating Fields and Concomitant Temozolomide

Authors: H. Ian Robins, HuyTram N. Nguyen, Aaron Field, Steven Howard, Shahriar Salamat, Dustin A. Deming

Source: Frontiers in Oncology, Vol 8 (2018)

Subject Terms: glioblastoma, tumor treating fields, optune®, genomics, temozolomide, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2018.00451/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/fa2370a183a644b3b68e1982957ecac3

Advances in immunotherapeutic strategies for colorectal cancer commentary on: tumoral immune cell exploitation in colorectal cancer metastases can be targeted effectively by anti-CCR5 therapy in cancer patients by Halama et al

Authors: Dustin A. Deming

Source: Journal for ImmunoTherapy of Cancer, Vol 4, Iss 1 (2016)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/4/1/93.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/3c68e8471d804f06a8281c448acec366

Precision medicine in colorectal cancer: the molecular profile alters treatment strategies

Authors: Nguyen H. Tran, Ludimila L. Cavalcante, Sam J. Lubner, Daniel L. Mulkerin, Noelle K. LoConte, Linda Clipson, Kristina A. Matkowskyj, Dustin A. Deming

Source: Therapeutic Advances in Medical Oncology, Vol 7 (2015)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/c25529980d874e598914258b273dd480

The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer.

Authors: Jennifer K Pleiman, Amy A Irving, Zhishi Wang, Erik Toraason, Linda Clipson, William F Dove, Dustin A Deming, Michael A Newton

Source: PLoS Genetics, Vol 14, Iss 9, p e1007611 (2018)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC6143270?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/8f6eb91913e744ebb694031853f1d680

Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K.

Authors: Alexander E Yueh, Susan N Payne, Alyssa A Leystra, Dana R Van De Hey, Tyler M Foley, Cheri A Pasch, Linda Clipson, Kristina A Matkowskyj, Dustin A Deming

Source: PLoS ONE, Vol 11, Iss 2, p e0148730 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4749659?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/43d47cd50a744f7b938ac68fd1de464b

Phospholipid ether analogs for the detection of colorectal tumors.

Authors: Dustin A Deming, Molly E Maher, Alyssa A Leystra, Joseph P Grudzinski, Linda Clipson, Dawn M Albrecht, Mary Kay Washington, Kristina A Matkowskyj, Lance T Hall, Sam J Lubner, Jamey P Weichert, Richard B Halberg

Source: PLoS ONE, Vol 9, Iss 10, p e109668 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4186834?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d90497f5ff9945f6b8b2860f54bd5187

mTOR inhibition elicits a dramatic response in PI3K-dependent colon cancers.

Authors: Dustin A Deming, Alyssa A Leystra, Mohammed Farhoud, Laura Nettekoven, Linda Clipson, Dawn Albrecht, Mary Kay Washington, Ruth Sullivan, Jamey P Weichert, Richard B Halberg

Source: PLoS ONE, Vol 8, Iss 4, p e60709 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3621889?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d31eff1ed832492ba8863e2f9091656e