The essential malaria protein PfCyRPA targets glycans to invade erythrocytes

Authors: Day, Christopher J. ^{1, 9}, Favuzza, Paola ^{2, 3, 8, 9}, Bielfeld, Sabrina ^{4, 5}, Haselhorst, Thomas ¹, Seefeldt, Leonie ^{2, 3}, Hauser, Julia ^{2, 3}, Shewell, Lucy K. ¹, Flueck, Christian ^{2, 3}, Poole, Jessica ¹, Jen, Freda E.-C. ¹, Schäfer, Anja ^{2, 3}, Dangy, Jean-Pierre ^{2, 3}, Gilberger, Tim-W. ^{4, 5, 6}, França, Camila Tenorio ⁷, Duraisingh, Manoj T. ⁷, Tamborrini, Marco ^{2, 3}, Brancucci, Nicolas M.B. ^{2, 3}, Grüring, Christof ^{2, 3}, Filarsky, Michael ^{4, 5}, Jennings, Michael P. ^{1, ∗}, Pluschke, Gerd ^{2, 3, 10, ∗∗}

Source: In Cell Reports 23 April 2024 43(4)

Hungry for control: metabolite signaling to chromatin in Plasmodium falciparum

Authors: Lappalainen, Ruth, Kumar, Manish, Duraisingh, Manoj T

Source: In Current Opinion in Microbiology April 2024 78

F‐erythrocytes promote Plasmodium falciparum proliferation in sickle cell disease

Authors: Archer, Natasha M., Gnangnon, Bénédicte, Mikdar, Mahmoud, Ciuculescu, Marioara F., Petersen, Nicole, Staffa, Steven J., Duraisingh, Manoj T.

Source: American journal of hematology. 98(10):1598-1605

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192007245.0x000001&indx=1&recIds=ETOCvdc_100192007245.0x000001

Applying Faster R-CNN for Object Detection on Malaria Images

Authors: Hung, Jane, Ravel, Deepali, Lopes, Stefanie C. P., Rangel, Gabriel, Nery, Odailton Amaral, Malleret, Benoit, Nosten, Francois, Lacerda, Marcus V. G., Ferreira, Marcelo U., Rénia, Laurent, Duraisingh, Manoj T., Costa, Fabio T. M., Marti, Matthias, Carpenter, Anne E.

Subject Terms: Computer Science - Computer Vision and Pattern Recognition

Access URL: http://arxiv.org/abs/1804.09548

Molecular mechanisms of cellular quiescence in apicomplexan parasites

Authors: Keroack, Caroline D, Duraisingh, Manoj T

Source: In Current Opinion in Microbiology December 2022 70

RBC membrane biomechanics and Plasmodium falciparum invasion: probing beyond ligand–receptor interactions

Authors: Groomes, Patrice V., Kanjee, Usheer, Duraisingh, Manoj T.

Source: Trends in parasitology. 38(4):302-315

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157326765.0x000001&indx=1&recIds=ETOCvdc_100157326765.0x000001

Deconstructing the parasite multiplication rate of Plasmodium falciparum

Authors: Gnangnon, Bénédicte, Duraisingh, Manoj T., Buckee, Caroline O.

Source: In Trends in Parasitology October 2021 37(10):922-932

The molecular basis of antimalarial drug resistance in Plasmodium vivax

Authors: Buyon, Lucas E., Elsworth, Brendan, Duraisingh, Manoj T.

Source: In International Journal for Parasitology: Drugs and Drug Resistance August 2021 16:23-37

Linking nutrient sensing and gene expression in Plasmodium falciparum blood‐stage parasites

Authors: Kumar, Manish, Skillman, Kristen, Duraisingh, Manoj T.

Source: Molecular microbiology. 115(5):891-900

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122949086.0x000001&indx=1&recIds=ETOCvdc_100122949086.0x000001

A framework for signaling throughout the life cycle of Babesia species

Authors: Elsworth, Brendan, Duraisingh, Manoj T.

Source: Molecular microbiology. 115(5):882-890

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122949073.0x000001&indx=1&recIds=ETOCvdc_100122949073.0x000001

Does fetal hemoglobin inhibit the malarial parasite Plasmodium falciparum?

Authors: Archer, Natasha M., Pasvol, Geoffrey, Wilson, Iain, Duraisingh, Manoj T.

Source: American journal of hematology. 97(9):E325-E327

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157722761.0x000001&indx=1&recIds=ETOCvdc_100157722761.0x000001

Fetal hemoglobin does not inhibit Plasmodium falciparum growth

Authors: Archer, Natasha M., Petersen, Nicole, Duraisingh, Manoj T.

Source: In Blood Advances 23 July 2019 3(14):2149-2152

Elucidating Host Cell Uptake by Malaria Parasites

Authors: Elsworth, Brendan, Keroack, Caroline D., Duraisingh, Manoj T.

Source: In Trends in Parasitology May 2019 35(5):333-335

A rising tide of parasite transcriptomics propels pathogen biology.

Authors: Duraisingh, Manoj T.¹ (AUTHOR) mduraisi@hsph.harvard.edu, Gubbels, Marc-Jan² (AUTHOR), Zarringhalam, Kourosh^3,4 (AUTHOR)

Source: PLoS Biology. 1/25/2023, Vol. 21 Issue 1, p1-4. 4p. 1 Color Photograph.

Subject Terms: *PLASMODIUM falciparum, *PLASMODIUM, *BIOLOGY, *PARASITES, *TRANSCRIPTOMES

Three Signatures of Adaptive Polymorphism Exemplified by Malaria-Associated Genes

Authors: Tennessen, Jacob A, Duraisingh, Manoj T

Source: Molecular biology and evolution. 38(4):1356-1371

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100143351122.0x000001&indx=1&recIds=ETOCvdc_100143351122.0x000001

Disruption of Plasmodium falciparum kinetochore proteins destabilises the nexus between the centrosome equivalent and the mitotic apparatus.

Authors: Li, Jiahong, Shami, Gerald J., Liffner, Benjamin, Cho, Ellie, Braet, Filip, Duraisingh, Manoj T., Absalon, Sabrina, Dixon, Matthew W. A., Tilley, Leann

Source: Nature Communications; 7/10/2024, Vol. 15 Issue 1, p1-16, 16p

Subject Terms: KINETOCHORE, PLASMODIUM falciparum, CENTROMERE, SPINDLE apparatus, NUCLEAR membranes, ORGANELLES, KARYOKINESIS

Descriptive, Hospital-Based, 10-Year Study of Malaria Transmission in Goa, a Southwest Indian State in the Malaria Elimination Phase.

Authors: Chakrabarti, Rimi, Gillespie, Kevin, Walke, Jayashri T., Fernandes, Mezia, Almeida, Anvily, Chery-Karschney, Laura, Kanjee, Usheer, Skillman, Kristen M., White, John, Babar, Prasad H., Pereira, Ligia, Mascarenhas, Anjali, Vaz, Marina, Khandeparkar, Anar, Gomes, Edwin, Janes, Holly, Rathod, Pradipsinh K., Duraisingh, Manoj T.

Source: American Journal of Tropical Medicine & Hygiene; Jul2024, Vol. 111 Issue 1, p11-25, 15p

To kill a piroplasm: genetic technologies to advance drug discovery and target identification in Babesia

Authors: Keroack, Caroline D., Elsworth, Brendan, Duraisingh, Manoj T.

Source: In International Journal for Parasitology February 2019 49(2):153-163

Resistance to Plasmodium falciparum in sickle cell trait erythrocytes is driven by oxygen-dependent growth inhibition

Authors: Archer, Natasha M., Petersen, Nicole, Clark, Martha A., Buckee, Caroline O., Childs, Lauren M., Duraisingh, Manoj T.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Jul 01. 115(28), 7350-7355.

Access URL: https://www.jstor.org/stable/26510900

NK cell-induced damage to P.falciparum-infected erythrocytes requires ligand-specific recognition and releases parasitophorous vacuoles that are phagocytosed by monocytes in the presence of immune IgG.

Authors: Sekar, Padmapriya¹, Rajagopalan, Sumati¹, srajagop@niaid.nih.gov, Shabani, Estela², Kanjee, Usheer², Schureck, Marc A.³, Arora, Gunjan¹, Peterson, Mary E.^1,4, Traore, Boubacar⁵, Crompton, Peter D.⁴, Duraisingh, Manoj T.², Desai, Sanjay A.³, Long, Eric O.¹, srajagop@niaid.nih.gov

Source: PLoS Pathogens; 11/8/2023, Vol. 19 Issue 11, p1-29, 29p