DrugMap: A quantitative pan-cancer analysis of cysteine ligandability

Authors: Takahashi, Mariko, Chong, Harrison B., Zhang, Siwen, Yang, Tzu-Yi, Lazarov, Matthew J., Harry, Stefan, Maynard, Michelle, Hilbert, Brendan, White, Ryan D., Murrey, Heather E., Tsou, Chih-Chiang, Vordermark, Kira, Assaad, Jonathan, Gohar, Magdy, Dürr, Benedikt R., Richter, Marianne, Patel, Himani, Kryukov, Gregory, Brooijmans, Natasja, Alghali, Aliyu Sidi Omar, Rubio, Karla, Villanueva, Antonio, Zhang, Junbing, Ge, Maolin, Makram, Farah, Griesshaber, Hanna, Harrison, Drew, Koglin, Ann-Sophie, Ojeda, Samuel, Karakyriakou, Barbara, Healy, Alexander, Popoola, George, Rachmin, Inbal, Khandelwal, Neha, Neil, Jason R., Tien, Pei-Chieh, Chen, Nicholas, Hosp, Tobias, van den Ouweland, Sanne, Hara, Toshiro, Bussema, Lillian, Dong, Rui, Shi, Lei, Rasmussen, Martin Q., Domingues, Ana Carolina, Lawless, Aleigha, Fang, Jacy, Yoda, Satoshi, Nguyen, Linh Phuong, Reeves, Sarah Marie, Wakefield, Farrah Nicole, Acker, Adam, Clark, Sarah Elizabeth, Dubash, Taronish, Kastanos, John, Oh, Eugene, Fisher, David E., Maheswaran, Shyamala, Haber, Daniel A., Boland, Genevieve M., Sade-Feldman, Moshe, Jenkins, Russell W., Hata, Aaron N., Bardeesy, Nabeel M., Suvà, Mario L., Martin, Brent R., Liau, Brian B., Ott, Christopher J., Rivera, Miguel N., Lawrence, Michael S., Bar-Peled, Liron

Source: In Cell 9 May 2024 187(10):2536-2556

TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state

Authors: Matsuda, Satoru, Revandkar, Ajinkya, Dubash, Taronish D., Ravi, Arvind, Wittner, Ben S., Lin, Maoxuan, Morris, Robert, Burr, Risa, Guo, Hongshan, Seeger, Karsen, Szabolcs, Annamaria, Che, Dante, Nieman, Linda, Getz, Gad A., Ting, David T., Lawrence, Michael S., Gainor, Justin, Haber, Daniel A., Maheswaran, Shyamala

Source: In Cell Reports 28 March 2023 42(3)

Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells

Authors: Mishra, Avanish, Dubash, Taronish D., Edd, Jon F., Jewett, Michelle K., Garre, Suhaas G., Karabacak, Nezihi Murat, Rabe, Daniel C., Mutlu, Baris R., Walsh, John R., Kapur, Ravi, Stott, Shannon L., Maheswaran, Shyamala, Haber, Daniel A., Toner, Mehmet

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jul . 117(29), 16839-16847.

Access URL: https://www.jstor.org/stable/26935385

NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer

Authors: Guo, Hongshan, Golczer, Gabriel, Wittner, Ben S., Langenbucher, Adam, Zachariah, Marcus, Dubash, Taronish D., Hong, Xin, Comaills, Valentine, Burr, Risa, Ebright, Richard Y., Horwitz, Elad, Vuille, Joanna A., Hajizadeh, Soroush, Wiley, Devon F., Reeves, Brittany A., Zhang, Jia-min, Niederhoffer, Kira L., Lu, Chenyue, Wesley, Benjamin, Ho, Uyen, Nieman, Linda T., Toner, Mehmet, Vasudevan, Shobha, Zou, Lee, Mostoslavsky, Raul, Maheswaran, Shyamala, Lawrence, Michael S., Haber, Daniel A.

Source: In Molecular Cell 7 October 2021 81(19):4041-4058

Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish

Authors: Yan, Chuan, Brunson, Dalton C., Tang, Qin, Do, Daniel, Iftimia, Nicolae A., Moore, John C., Hayes, Madeline N., Welker, Alessandra M., Garcia, Elaine G., Dubash, Taronish D., Hong, Xin, Drapkin, Benjamin J., Myers, David T., Phat, Sarah, Volorio, Angela, Marvin, Dieuwke L., Ligorio, Matteo, Dershowitz, Lyle, McCarthy, Karin M., Karabacak, Murat N., Fletcher, Jonathan A., Sgroi, Dennis C., Iafrate, John A., Maheswaran, Shyamala, Dyson, Nick J., Haber, Daniel A., Rawls, John F., Langenau, David M.

Source: In Cell 13 June 2019 177(7):1903-1914

In-flow measurement of cell–cell adhesion using oscillatory inertial microfluidicsElectronic supplementary information (ESI) available. See DOI:10.1039/d0lc00089b

Authors: Mutlu, Baris R., Dubash, Taronish, Dietsche, Claudius, Mishra, Avanish, Ozbey, Arzu, Keim, Kevin, Edd, Jon F., Haber, Daniel A., Maheswaran, Shyamala, Toner, Mehmet

Source: Lab on a chip. 20(9):1612-1620

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108974446.0x000001&indx=1&recIds=ETOCvdc_100108974446.0x000001

Microfluidic concentration and separation of circulating tumor cell clusters from large blood volumesElectronic supplementary information (ESI) available. See DOI: 10.1039/c9lc01122f

Authors: Edd, Jon F., Mishra, Avanish, Dubash, Taronish D., Herrera, Stefan, Mohammad, Ridhwan, Williams, E. Kendall, Hong, Xin, Mutlu, Baris R., Walsh, John R., Machado de Carvalho, Fernanda, Aldikacti, Berent, Nieman, Linda T., Stott, Shannon L., Kapur, Ravi, Maheswaran, Shyamala, Haber, Daniel A., Toner, Mehmet

Source: Lab on a chip. 20(3):558-567

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100098707654.0x000001&indx=1&recIds=ETOCvdc_100098707654.0x000001

Blood-based monitoring identifies acquired and targetable driver HER2 mutations in endocrine-resistant metastatic breast cancer

Authors: Medford, Arielle, Dubash, Taronish, Juric, Dejan, Spring, Laura, Niemierko, Andrzej, Vidula, Neelima, Peppercorn, Jeffrey, Isakoff, Steven, Reeves, Brittany, LiCausi, Joseph, Wesley, Benjamin, Malvarosa, Giuliana, Yuen, Megan, Wittner, Ben, Lawrence, Michael, Iafrate, A., Ellisen, Leif, Moy, Beverly, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel, Bardia, Aditya

Source: Npj precision oncology. 3(1):1-9

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185369924.0x000001&indx=1&recIds=ETOCvdc_100185369924.0x000001

SETD1A protects from senescence through regulation of the mitotic gene expression program

Authors: Tajima, Ken, Matsuda, Satoru, Yae, Toshifumi, Drapkin, Benjamin, Morris, Robert, Boukhali, Myriam, Niederhoffer, Kira, Comaills, Valentine, Dubash, Taronish, Nieman, Linda, Guo, Hongshan, Magnus, Neelima, Dyson, Nick, Shioda, Toshihiro, Haas, Wilhelm, Haber, Daniel, Maheswaran, Shyamala

Source: Nature communications. 10(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182783990.0x000001&indx=1&recIds=ETOCvdc_100182783990.0x000001

Asymmetric Centriole Numbers at Spindle Poles Cause Chromosome Missegregation in Cancer

Authors: Cosenza, Marco R., Cazzola, Anna, Rossberg, Annik, Schieber, Nicole L., Konotop, Gleb, Bausch, Elena, Slynko, Alla, Holland-Letz, Tim, Raab, Marc S., Dubash, Taronish, Glimm, Hanno, Poppelreuther, Sven, Herold-Mende, Christel, Schwab, Yannick, Krämer, Alwin

Source: In Cell Reports 22 August 2017 20(8):1906-1920

Phenotypic differentiation does not affect tumorigenicity of primary human colon cancer initiating cells

Authors: Dubash, Taronish D., Hoffmann, Christopher M., Oppel, Felix, Giessler, Klara M., Weber, Sarah, Dieter, Sebastian M., Hüllein, Jennifer, Zenz, Thorsten, Herbst, Friederike, Scholl, Claudia, Weichert, Wilko, Werft, Wiebke, Benner, Axel, Schmidt, Manfred, Schneider, Martin, Glimm, Hanno, Ball, Claudia R. ^*

Source: In Cancer Letters 28 February 2016 371(2):326-333

Succession of transiently active tumor‐initiating cell clones in human pancreatic cancer xenografts

Authors: Ball, Claudia R, Oppel, Felix, Ehrenberg, Karl Roland, Dubash, Taronish D, Dieter, Sebastian M, Hoffmann, Christopher M, Abel, Ulrich, Herbst, Friederike, Koch, Moritz, Werner, Jens, Bergmann, Frank, Ishaque, Naveed, Schmidt, Manfred, Kalle, Christof, Scholl, Claudia, Fröhling, Stefan, Brors, Benedikt, Weichert, Wilko, Weitz, Jürgen, Glimm, Hanno

Source: EMBO molecular medicine. 9(7):918-932

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187216330.0x000001&indx=1&recIds=ETOCvdc_100187216330.0x000001

Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer

Authors: Giessler, Klara M., Kleinheinz, Kortine, Huebschmann, Daniel, Balasubramanian, Gnana Prakash, Dubash, Taronish D., Dieter, Sebastian M., Siegl, Christine, Herbst, Friederike, Weber, Sarah, Hoffmann, Christopher M.

Source: Journal of experimental medicine. 214(7):2073-2088

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN611974600&indx=1&recIds=ETOCRN611974600

Correction to: Regulation of GAD65 expression by SMAR1 and p53 upon Streptozotocin treatment

Authors: Singh, Sandeep, Raina, Varsheish, Chavali, Pavithra Lakshminarsimhan, Dubash, Taronish, Kadreppa, Sreenath, Parab, Pradeep, Chattopadhyay, Samit

Source: BMC molecular and cell biology. 21(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171748884.0x000001&indx=1&recIds=ETOCvdc_100171748884.0x000001

Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells.

Authors: Dubash, Taronish D., Bardia, Aditya, Chirn, Brian, Reeves, Brittany A., LiCausi, Joseph A., Burr, Risa, Wittner, Ben S., Rai, Sumit, Patel, Hitisha, Bihani, Teeru, Arlt, Heike, Bidard, Francois-Clement, Kaklamani, Virginia G., Aftimos, Philippe, Cortés, Javier, Scartoni, Simona, Fiascarelli, Alessio, Binaschi, Monica, Habboubi, Nassir, Iafrate, A. John

Source: Breast Cancer Research & Treatment; Aug2023, Vol. 201 Issue 1, p43-56, 14p

The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo

Authors: Weber, Sarah, Koschade, Sebastian E., Hoffmann, Christopher M., Dubash, Taronish D., Giessler, Klara M., Dieter, Sebastian M., Herbst, Friederike, Glimm, Hanno, Ball, Claudia R.

Source: BMC cancer. 19(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192968907.0x000001&indx=1&recIds=ETOCvdc_100192968907.0x000001

A Gene Panel Associated With Abemaciclib Utility in ESR1 -Mutated Breast Cancer After Prior Cyclin-Dependent Kinase 4/6-Inhibitor Progression.

Authors: Brett, Jamie O.^1,2 (AUTHOR), Dubash, Taronish D.¹ (AUTHOR), Johnson, Gabriela N.² (AUTHOR), Niemierko, Andrzej¹ (AUTHOR), Mariotti, Veronica^3,4 (AUTHOR), Kim, Leslie S.L.⁵ (AUTHOR), Xi, Jing⁶ (AUTHOR), Pandey, Apurva⁷ (AUTHOR), Dunne, Siobhan⁵ (AUTHOR), Nasrazadani, Azadeh^7,8 (AUTHOR), Lloyd, Maxwell R.^2,9 (AUTHOR), Kambadakone, Avinash¹ (AUTHOR), Spring, Laura M.¹ (AUTHOR), Micalizzi, Douglas S.¹ (AUTHOR), Onozato, Maristela L.¹ (AUTHOR), Che, Dante¹ (AUTHOR), Nayar, Utthara² (AUTHOR), Brufsky, Adam⁷ (AUTHOR), Kalinsky, Kevin^10,11 (AUTHOR), Ma, Cynthia X.⁶ (AUTHOR)

Source: JCO Precision Oncology. 5/4/2023, Vol. 7, p1-14. 14p.

Subject Terms: *EPIDERMAL growth factor receptors, *METASTATIC breast cancer, *BREAST cancer, *CYCLIN-dependent kinase inhibitors, *CYCLIN-dependent kinases

Evaluation of endocrine resistance using ESR1 genotyping of circulating tumor cells and plasma DNA.

Authors: Sundaresan, Tilak K., Dubash, Taronish D., Zheng, Zongli, Bardia, Aditya, Wittner, Ben S., Aceto, Nicola, Silva, Erin J., Fox, Douglas B., Liebers, Matthew, Kapur, Ravi, Iafrate, John, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.

Source: Breast Cancer Research & Treatment; Jul2021, Vol. 188 Issue 1, p43-52, 10p

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.