Human embryonic stem cell spheroids derived exosomal hsa_circ_0003258 sequestered dual targeting of miR-502-5p on KLF4/NF-κB and GALNT4/P53 to mitigate inflammation and apoptosis in hepatic ischemia reperfusion injury

Authors: Wang, Ning, Zhang, Yuwei, Zhang, Shuai, Chen, Chuxin, Wu, Haibin, Liao, Peilin, Liu, Shoupei, Chen, Sen, Zhang, Xueyan, Xie, Jinghe, Guo, Tingting, Liang, Yan, Wang, Yiyu, Li, Xiajing, Tang, Xianglian, Gu, Weili, Cao, Jie, Duan, Yuyou

Source: In Chemical Engineering Journal 15 December 2024 502

Polyphenol-mediated biomimetic mineralization of sacrificial metal-organic framework nanoparticles for wound healing

Authors: Zhan, Xiaolong, Wen, Zhengbo, Chen, Xi, Lei, Qi, Chen, Yuxin, Zhou, Liang, Zheng, Guansheng, Kong, Fanhui, Guo, Jimin, Duan, Yuyou, Lai, Yuyan, Yin, Panchao, Brinker, C. Jeffrey, Chen, Honglin, Zhu, Wei

Source: In Cell Reports Physical Science 16 November 2022 3(11)

Establishment of a 3D model of tumor-driven angiogenesis to study the effects of anti-angiogenic drugs on pericyte recruitmentElectronic supplementary information (ESI) available. See DOI: 10.1039/d0bm02107e

Authors: Qiu, Yaqi, Wang, Ning, Guo, Tingting, Liu, Shoupei, Tang, Xianglian, Zhong, Zhiyong, Chen, Qicong, Wu, Haibin, Li, Xiajing, Wang, Jue, Zhang, Shuai, Ou, Yimeng, Wang, Bailin, Ma, Keqiang, Gu, Weili, Cao, Jie, Chen, Honglin, Duan, Yuyou

Source: Biomaterials science. 9(18):6064-6085

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128973747.0x000001&indx=1&recIds=ETOCvdc_100128973747.0x000001

Generation of Functioning Platelets from Mature Megakaryocytes Derived from CD34⁺ Umbilical Cord Blood Cells.

Authors: Zhong, Zhiyong, Chen, Chuxin, Wang, Ning, Qiu, Yaqi, Li, Xiajing, Liu, Shoupei, Wu, Haibin, Tang, Xianglian, Fu, Yingjie, Chen, Qicong, Guo, Tingting, Wei, Yaming, Duan, Yuyou

Source: Stem Cells & Development; Dec2024, Vol. 33 Issue 23/24, p677-691, 15p

Highly efficient generation of mature megakaryocytes and functional platelets from human embryonic stem cells.

Authors: Chen, Chuxin, Wang, Ning, Zhang, Xueyan, Fu, Yingjie, Zhong, Zhiyong, Wu, Haibin, Wei, Yaming, Duan, Yuyou

Source: Stem Cell Research & Therapy; 11/28/2024, Vol. 15 Issue 1, p1-22, 22p

Subject Terms: HUMAN embryonic stem cells, PROGENITOR cells, BLOOD transfusion, BLOOD platelet transfusion, RNA analysis

Isolation and identification of patient-derived liver cancer stem cells and development of personalized treatment strategies.

Authors: Guo, Tingting, Zhang, Shuai, Zeng, Weiping, Liang, Yan, Xie, Jinghe, Liu, ShouPei, Qiu, Yaqi, Fu, Yingjie, Ou, Yimeng, Ma, Keqiang, Wang, Bailin, Gu, Weili, Duan, Yuyou

Source: Journal of Translational Medicine; 11/18/2024, Vol. 22 Issue 1, p1-21, 21p

Subject Terms: STEM cell culture, CANCER stem cells, LIVER cancer, GENE expression, GENE expression profiling

In Situ Precision Cell Electrospinning as an Efficient Stem Cell Delivery Approach for Cutaneous Wound Healing

Authors: Wen, Zhengbo, Chen, Yuxin, Liao, Peilin, Wang, Fengyu, Zeng, Weiping, Liu, Shoupei, Wu, Haibing, Wang, Ning, Moroni, Lorenzo, Zhang, Minmin, Duan, Yuyou, Chen, Honglin

Source: Advanced healthcare materials. 12(26)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196407243.0x000001&indx=1&recIds=ETOCvdc_100196407243.0x000001

The combination of dextran sulphate and polyvinyl alcohol prevents excess aggregation and promotes proliferation of pluripotent stem cells in suspension culture

Authors: Tang, Xianglian, Wu, Haibin, Xie, Jinghe, Wang, Ning, Chen, Qicong, Zhong, Zhiyong, Qiu, Yaqi, Wang, Jue, Li, Xiajing, Situ, Ping, Lai, Liangxue, Zern, Mark A, Chen, Honglin, Duan, Yuyou

Source: Cell proliferation. 54(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130127267.0x000001&indx=1&recIds=ETOCvdc_100130127267.0x000001

Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2

Authors: Zhang, Yanhong, Qian, Yingjuan, Zhang, Jin, Yan, Wensheng, Jung, Yong-Sam, Chen, Mingyi, Huang, Eric, Lloyd, Kent, Duan, Yuyou, Wang, Jian

Source: Genes & development. 31(12):1243-1256

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN612365001&indx=1&recIds=ETOCRN612365001

Establishment of a prognostic model based on m⁶A regulatory factors and stemness of hepatocellular carcinoma using RNA-seq data and scRNA-seq data.

Authors: Liang, Yan, Chen, Sen, Xie, Jinghe, Yan, Guanrong, Guo, Tingting, Li, Tianyang, Liu, Shoupei, Zeng, Weiping, Zhang, Shuai, Ma, Keqiang, Chen, Honglin, Ou, Yimeng, Wang, Bailin, Gu, Weili, Duan, Yuyou

Source: Journal of Cancer Research & Clinical Oncology; Nov2023, Vol. 149 Issue 14, p12881-12896, 16p

Subject Terms: PROGNOSTIC models, STEM cell factor, CANCER prognosis, CANCER stem cells, RNA sequencing

Pharmacophore hybridisation and nanoscale assembly to discover self-delivering lysosomotropic new-chemical entities for cancer therapy

Authors: Ma, Zhao, Li, Jin, Lin, Kai, Ramachandran, Mythili, Zhang, Dalin, Showalter, Megan, De Souza, Cristabelle, Lindstrom, Aaron, Solano, Lucas N., Jia, Bei, Urayama, Shiro, Duan, Yuyou, Fiehn, Oliver, Lin, Tzu-yin, Li, Minyong, Li, Yuanpei

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174510266.0x000001&indx=1&recIds=ETOCvdc_100174510266.0x000001

Hepatic differentiation from human mesenchymal stem cells on a novel nanofiber scaffold

Authors: Ghaedi, Mahboobe, Soleimani, Masoud, Shabani, Iman, Duan, Yuyou, Lotfi, Abbas

Source: Cellular & molecular biology letters. 17(1):89-106

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165259721.0x000001&indx=1&recIds=ETOCvdc_100165259721.0x000001

Exosomes as Carriers for Drug Delivery in Cancer Therapy.

Authors: Zeng, Weiping, Wen, Zhengbo, Chen, Honglin, Duan, Yuyou

Source: Pharmaceutical Research; Apr2023, Vol. 40 Issue 4, p873-887, 15p

Subject Terms: DRUG carriers, EXOSOMES, CANCER treatment, EXTRACELLULAR vesicles, VESICLES (Cytology), ANTINEOPLASTIC agents, NANOMEDICINE

C/EBPβ Coupled with E2F2 Promoted the Proliferation of hESC-Derived Hepatocytes through Direct Binding to the Promoter Regions of Cell-Cycle-Related Genes.

Authors: Liu, Shoupei, Wang, Jue, Chen, Sen, Han, Zonglin, Wu, Haibin, Chen, Honglin, Duan, Yuyou

Source: Cells (2073-4409); Feb2023, Vol. 12 Issue 3, p497, 21p

Subject Terms: PROMOTERS (Genetics), HUMAN embryonic stem cells, LIVER cells, GENE expression, LIVER regeneration, RNA analysis, DNA replication

Hepatic Polarized Differentiation Promoted the Maturity and Liver Function of Human Embryonic Stem Cell-Derived Hepatocytes via Activating Hippo and AMPK Signaling Pathways.

Authors: Wang, Jue, Situ, Ping, Chen, Sen, Wu, Haibin, Zhang, Xueyan, Liu, Shoupei, Wang, Yiyu, Xie, Jinghe, Chen, Honglin, Duan, Yuyou

Source: Cells (2073-4409); Dec2022, Vol. 11 Issue 24, p4117, 20p

Subject Terms: LIVER cells, LIVER, BIOLOGICAL transport, GENE expression profiling, LIVER regeneration, CELL physiology, DRUG metabolism, EMBRYONIC stem cells

KAT2A / E2F1 Promotes Cell Proliferation and Migration via Upregulating the Expression of UBE2C in Pan-Cancer.

Authors: Lin, Shudai, Qiu, Li, Liang, Keying, Zhang, Haibo, Xian, Mingjian, Chen, Zixi, Wei, Jinfen, Fu, Shuying, Gong, Xiaocheng, Ding, Ke, Zhang, Zihao, Hu, Bowen, Zhang, Xiquan, Duan, Yuyou, Du, Hongli

Source: Genes; Oct2022, Vol. 13 Issue 10, pN.PAG-N.PAG, 21p

Subject Terms: UBIQUITIN-conjugating enzymes, CELL migration, CELL proliferation, CANCER cell migration, CELL cycle, UBIQUITINATION, WESTERN immunoblotting

Construction of tandem diabody (IL-6/CD20)-secreting human umbilical cord mesenchymal stem cells and its experimental treatment on diffuse large B cell lymphoma.

Authors: Zhang, Jiayi, Zhong, Minglu, Zhong, Weijie, Lan, Yanfei, Yuan, Zhaohu, Duan, Yuyou, Wei, Yaming

Source: Stem Cell Research & Therapy; 9/14/2022, Vol. 13 Issue 1, p1-15, 15p

Subject Terms: B cell lymphoma, MESENCHYMAL stem cells, STEM cell treatment, UMBILICAL cord, B cells, BINDING site assay

CircRNA.0007127 triggers apoptosis through the miR-513a-5p/CASP8 axis in K-562 cells.

Alternate Title: CircRNA.0007127通过miR-513a-5p/CASP8轴触发K-562细胞凋亡. (Chinese)

Authors: Li, Xiajing, Zhang, Yiyu, Wang, Ning, Yuan, Zhaohu, Chen, Xiaojie, Chen, Qicong, Deng, Hui, Tong, Xinxin, Chen, Honglin, Duan, Yuyou, Wei, Yaming

Source: Journal of Zhejiang University: Science B; Sep2022, Vol. 23 Issue 9, p732-746, 15p

Hypoxia drives hematopoiesis with the enhancement of T lineage through eliciting arterial specification of hematopoietic endothelial progenitors from hESC.

Authors: Wang, Ning, Chen, Chuxin, Cheng, Yang, Fu, Yingjie, Zhong, Zhiyong, Yang, Yu, Lv, Ling, Chen, Honglin, Huang, Jian, Duan, Yuyou

Source: Stem Cell Research & Therapy; 6/28/2022, Vol. 13 Issue 1, p1-20, 20p

Subject Terms: HEMATOPOIESIS, HUMAN embryonic stem cells, HEMATOPOIETIC stem cell transplantation, PLURIPOTENT stem cells, HUMAN stem cells, HYPOXEMIA, PROGENITOR cells

Dextran sulfate prevents excess aggregation of human pluripotent stem cells in 3D culture by inhibiting ICAM1 expression coupled with down-regulating E-cadherin through activating the Wnt signaling pathway.

Authors: Wu, Haibin, Tang, Xianglian, Wang, Yiyu, Wang, Ning, Chen, Qicong, Xie, Jinghe, Liu, Shoupei, Zhong, Zhiyong, Qiu, Yaqi, Situ, Ping, Zern, Mark A., Wang, Jue, Chen, Honglin, Duan, Yuyou

Source: Stem Cell Research & Therapy; 5/26/2022, Vol. 13 Issue 1, p1-20, 20p

Subject Terms: STEM cell culture, HUMAN stem cells, WNT signal transduction, PLURIPOTENT stem cells, DEXTRAN sulfate, CD54 antigen, CELL culture