Design and modeling of order of addition experiment with component effects

Authors: Junjian Liu, Yifan Tang, Ting Lan

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Drug combination therapy, Order of addition experiment, D-efficiency, Component effect, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/c4d6f49337cb4ce2b08193f42c3b43a4

Triple-drug combination therapy versus six-month proton pump inhibitor monotherapy in non-Helicobacter pylori Helicobacter eradication, and hyperacid environment preference of Helicobacter suis: a clinical study

Authors: Toshihisa Tsukadaira, Seiichi Hayashi, Hiroyoshi Ota, Natsuko Kobayashi, Hiroyuki Agawa, Himiko Kodaira, Yasuhiro Sekiguchi, Takehisa Matsumoto, Kazuki Horiuchi, Tatsuya Negishi, Toshifumi Tada

Source: BMC Gastroenterology, Vol 24, Iss 1, Pp 1-7 (2024)

Subject Terms: Non-Helicobacter pylori Helicobacter, Helicobacter suis, Eradication, Triple-drug combination therapy, Proton pump inhibitor, Gender, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1471-230X

Access URL: https://doaj.org/article/63cea37efb2a4bf997eb6920774b9c05

A multimodal precision-prevention approach combining lifestyle intervention with metformin repurposing to prevent cognitive impairment and disability: the MET-FINGER randomised controlled trial protocol

Authors: Mariagnese Barbera, Jenni Lehtisalo, Dinithi Perera, Malin Aspö, Mary Cross, Celeste A. De Jager Loots, Emanuela Falaschetti, Naomi Friel, José A. Luchsinger, Hanna Malmberg Gavelin, Markku Peltonen, Geraint Price, Anna Stigsdotter Neely, Charlotta Thunborg, Jaakko Tuomilehto, Francesca Mangialasche, Lefkos Middleton, Tiia Ngandu, Alina Solomon, Miia Kivipelto, on behalf of the MET-FINGER study team

Source: Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)

Subject Terms: Alzheimer’s, Dementia prevention, Cognitive impairment, Lifestyle-drug combination therapy, Lifestyle intervention, Metformin, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1758-9193

Access URL: https://doaj.org/article/cf2e67842eb94bb2b2088bff9d888756

Novel Drug Combinations in Lung Cancer: New Potential Synergies Between 5-FU and Repurposed Drugs

Authors: Eduarda Ribeiro, Nuno Vale

Source: Applied Sciences, Vol 14, Iss 21, p 9658 (2024)

Subject Terms: A549 cell line, drug combination therapy, lung cancer, 5-FU, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3417/14/21/9658; https://doaj.org/toc/2076-3417

Access URL: https://doaj.org/article/c6075caa5fac4024a788ba55bbd676e7

Anti-ENO1 antibody combined with metformin against tumor resistance: a novel antibody-based platform

Authors: Xiong Shu, Hui Wen Zhang, Shi Ya Liu, Li Xin Sun, Tao Zhang, Yu Liang Ran

Source: PeerJ, Vol 12, p e16817 (2024)

Subject Terms: Antibody-based drug combination therapy, Cancer stem cells, Drug resistance, ENO1, Oncotherapy, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://peerj.com/articles/16817.pdf; https://peerj.com/articles/16817/; https://doaj.org/toc/2167-8359

Access URL: https://doaj.org/article/2ccf73ec7e4a4014aa6c3c72707ade67

Benefits and risks of drug combination therapy for diabetes mellitus and its complications: a comprehensive review

Authors: Xueqin Xie, Changchun Wu, Yuduo Hao, Tianyu Wang, Yuhe Yang, Peiling Cai, Yang Zhang, Jian Huang, Kejun Deng, Dan Yan, Hao Lin

Source: Frontiers in Endocrinology, Vol 14 (2023)

Subject Terms: diabetes, diabetic complications, diabetic management, drug combination therapy, blood glucose control, personalized medicine, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2023.1301093/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/54ce23fb289447d49c1a265a59d9eebb

AI-DrugNet: A network-based deep learning model for drug repurposing and combination therapy in neurological disorders

Authors: Xingxin Pan, Jun Yun, Zeynep H. Coban Akdemir, Xiaoqian Jiang, Erxi Wu, Jason H. Huang, Nidhi Sahni, S. Stephen Yi

Source: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1533-1542 (2023)

Subject Terms: Network model, Deep learning, Drug repurposing, Drug combination therapy, Neurological and developmental disorders, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S200103702300051X; https://doaj.org/toc/2001-0370

Access URL: https://doaj.org/article/20a864aabc5f4043b0ac3a7f59d4f919

Machine learning model for anti-cancer drug combinations: Analysis, prediction, and validation

Authors: Jing-Bo Zhou, Dongyang Tang, Lin He, Shiqi Lin, Josh Haipeng Lei, Heng Sun, Xiaoling Xu, Chu-Xia Deng

Source: Pharmacological Research, Vol 194, Iss , Pp 106830- (2023)

Subject Terms: Drug combination therapy, Machine learning, Three-dimensional tumor slice culture, Potential combination biomarkers, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S104366182300186X; https://doaj.org/toc/1096-1186

Access URL: https://doaj.org/article/96b73912b9154d6a84cfac543d5096ee

Liver fibrosis and MAFLD: the exploration of multi-drug combination therapy strategies

Authors: Qingfu Dong, Haolin Bao, Jiangang Wang, Wujiang Shi, Xinlei Zou, Jialin Sheng, Jianjun Gao, Canghai Guan, Haoming Xia, Jinglin Li, Pengcheng Kang, Yi Xu, Yunfu Cui, Xiangyu Zhong

Source: Frontiers in Medicine, Vol 10 (2023)

Subject Terms: liver fibrosis, metabolic-associated fatty liver disease (MAFLD), non-alcoholic steatohepatitis (NASH), cirrhosis, drug combination therapy, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2023.1120621/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/c1c61544b484405d932c7934fafa3512

Various Uses of PD1/PD-L1 Inhibitor in Oncology: Opportunities and Challenges

Authors: Zhitao Li, Guoqiang Sun, Guangshun Sun, Ye Cheng, Liangliang Wu, Qian Wang, Chengyu Lv, Yichan Zhou, Yongxiang Xia, Weiwei Tang

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: cancer, PD-1/PD-L1 inhibitors, drug combination therapy, immunotherapy, tumor microenvironment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.771335/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/dbccacbd762c4d9bb560d433c84be82a

Influenza Treatment: Limitations of Antiviral Therapy and Advantages of Drug Combination Therapy

Authors: Sania Batool, Santosh Chokkakula, Min-Suk Song

Source: Microorganisms, Vol 11, Iss 1, p 183 (2023)

Subject Terms: influenza virus, antiviral drugs, antiviral drug resistance, drug combination therapy, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2607/11/1/183; https://doaj.org/toc/2076-2607

Access URL: https://doaj.org/article/35c8dc47e8ed49a0b58ce19d99f1d5e1

Pre-eclampsia with severe features: management of antihypertensive therapy in the postpartum period

Authors: Nnabuike Chibuoke Ngene, Jagidesa Moodley

Source: The Pan African Medical Journal, Vol 36, Iss 216 (2020)

Subject Terms: alpha-methyldopa, antihypertensive drug combination therapy, amlodipine, postpartum hypertension, severe preeclampsia, Medicine

File Description: electronic resource

Relation: https://www.panafrican-med-journal.com/content/article/36/216/pdf/216.pdf; https://doaj.org/toc/1937-8688

Access URL: https://doaj.org/article/d49c3762fb8c4a759198de0d178a3302

Leucyl-tRNA Synthetase Inhibitor, D-Norvaline, in Combination with Oxacillin, Is Effective against Methicillin-Resistant Staphylococcus aureus

Authors: Hong-Ju Lee, Byungchan Kim, Suhyun Kim, Do-Hyun Cho, Heeju Jung, Wooseong Kim, Yun-Gon Kim, Jae-Seok Kim, Hwang-Soo Joo, Sang-Ho Lee, Yung-Hun Yang

Source: Antibiotics, Vol 11, Iss 5, p 683 (2022)

Subject Terms: MRSA, D-norvaline, aminoacyl-tRNA synthetase inhibitor, drug combination therapy, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/11/5/683; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/19621a5bd7fc435386fbb4ed1d3b5b31

Clofoctol and sorafenib inhibit prostate cancer growth via synergistic induction of endoplasmic reticulum stress and UPR pathways

Authors: Fan L, He Z, Head SA, Zhou Y, Lu T, Feng X, Zhang X, Zhang M, Dang Y, Jiang X, Wang M

Source: Cancer Management and Research, Vol Volume 10, Pp 4817-4829 (2018)

Subject Terms: drug combination therapy, prostate cancer, clofoctol, sorafenib, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.dovepress.com/clofoctol-and-sorafenib-inhibit-prostate-cancer-growth-via-synergistic-peer-reviewed-article-CMAR; https://doaj.org/toc/1179-1322

Access URL: https://doaj.org/article/f0484ab950a34254853f1ff6d42a6b06

Combination Therapy Using Low-Concentration Oxacillin with Palmitic Acid and Span85 to Control Clinical Methicillin-Resistant Staphylococcus aureus

Authors: Hun-Suk Song, Tae-Rim Choi, Shashi Kant Bhatia, Sun Mi Lee, Sol Lee Park, Hye Soo Lee, Yun-Gon Kim, Jae-Seok Kim, Wooseong Kim, Yung-Hun Yang

Source: Antibiotics, Vol 9, Iss 10, p 682 (2020)

Subject Terms: MRSA, drug combination therapy, palmitic acid, span85, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/9/10/682; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/c7fed4dc9f1e4f44b219aabc21a9cd63

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