Survival of the fittest: positive selection of CD4+ T cells expressing a membrane-bound fusion inhibitor following HIV-1 infection

Contributors: Kimpel, Janine, Qiu, Gang, Brendel, Christian, Humeau, Laurent M., Dropulic, Boro, Berger, Annemarie, Laer, Dorothee von, Braun, Stephen E., Wong, Fay Eng, Conolle, Michelle, Rossi, John J., Johnson, R. Paul, Schmitz, Jörn E.

Availability: http://data.europeana.eu/aggregation/europeana/2048441/item_2KBGJCVI4MFVQSSV4EH7T5IDDRIYZ7CP

Treatment of non-Hodgkin lymphoma with point-of-care manufactured CAR T cells: a dual institution, phase 1 trial

Authors: Ghobadi, Armin ^{a, n}, Caimi, Paolo F. ^{b, c, n, ∗}, Reese, Jane S. ^{b, d}, Goparaju, Krishna ^d, di Trani, Martina ^e, Ritchey, Julie ^c, Jackson, Zachary ^b, Tomlinson, Benjamin ^{b, d}, Schiavone, Jennifer M. ^d, Kleinsorge-Block, Sarah ^d, Zamborsky, Kayla ^d, Eissenberg, Linda ^a, Schneider, Dina ^f, Boughan, Kirsten M. ^g, Zabor, Emily C. ^c, Metheny, Leland ^{b, d}, Gallogly, Molly ^{b, d}, Kruger, Winfried ^f, Kadan, Michael ^f, Worden A.S, Andrew ^f, Sharma, Ashish ^h, Cooper, Brenda W. ^{b, d}, Otegbeye, Folashade ⁱ, Sekaly, Rafick P. ^h, Wald, David N. ^{b, d}, Carlo-Stella, Carmelo ^{e, j}, DiPersio, John ^a, Orentas, Rimas ^{k, l}, Dropulic, Boro ^l, de Lima, Marcos ^m

Source: In eClinicalMedicine March 2025 81

Place of care manufacturing of chimeric antigen receptor cells: Opportunities and challenges

Authors: Orentas, Rimas J., Dropulić, Boro, de Lima, Marcos

Source: In Seminars in Hematology January 2023 60(1):20-24

Developing Affordable Point of Care CAR-T Therapies: Expanding Efficacy & Impact

Authors: Orentas, Rimas, Dropulić, Boro

Source: Drug development & delivery. 22(6):32-37

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630205463&indx=1&recIds=ETOCRN630205463

Self-driving armored CAR-T cells overcome a suppressive milieu and eradicate CD19+ Raji lymphoma in preclinical models

Authors: Webster, Brian, Xiong, Ying, Hu, Peirong, Wu, Darong, Alabanza, Leah, Orentas, Rimas J., Dropulic, Boro, Schneider, Dina

Source: In Molecular Therapy 1 September 2021 29(9):2691-2706

Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice

Authors: Li, Dan, Li, Nan, Zhang, Yi-Fan, Fu, Haiying, Feng, Mingqian, Schneider, Dina, Su, Ling, Wu, Xiaolin, Zhou, Jing, Mackay, Sean, Kramer, Josh, Duan, Zhijian, Yang, Hongjia, Kolluri, Aarti, Hummer, Alissa M., Torres, Madeline B., Zhu, Hu, Hall, Matthew D., Luo, Xiaoling, Chen, Jinqiu, Wang, Qun, Abate-Daga, Daniel, Dropulic, Boro, Hewitt, Stephen M., Orentas, Rimas J., Greten, Tim F., Ho, Mitchell

Source: In Gastroenterology June 2020 158(8):2250-2265

Stable Transcriptional Repression and Parasitism of HIV-1

Authors: Shrivastava, Surya, Charlins, Paige, Ackley, Amanda, Embree, Heather, Dropulic, Boro, Akkina, Ramesh, Weinberg, Marc S., Morris, Kevin V.

Source: In Molecular Therapy - Nucleic Acids 7 September 2018 12:12-18

Closed-system manufacturing of CD19 and dual-targeted CD20/19 chimeric antigen receptor T cells using the CliniMACS Prodigy device at an academic medical center

Authors: Zhu, Fenlu, Shah, Nirav, Xu, Huiqing, Schneider, Dina, Orentas, Rimas, Dropulic, Boro, Hari, Parameswaran, Keever-Taylor, Carolyn A. ^*

Source: In Cytotherapy March 2018 20(3):394-406

Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma

Authors: Tian, Meijie, Wei, Jun S., Shivaprasad, Nityashree, Highfill, Steven L., Gryder, Berkley E., Milewski, David, Brown, G. Tom, Moses, Larry, Song, Hannah, Wu, Jerry T., Azorsa, Peter, Kumar, Jeetendra, Schneider, Dina, Chou, Hsien-Chao, Song, Young K., Rahmy, Abdelrahman, Masih, Katherine E., Kim, Yong Yean, Belyea, Brian, Linardic, Corinne M., Dropulic, Boro, Sullivan, Peter M., Sorensen, Poul H., Dimitrov, Dimiter S., Maris, John M., Mackall, Crystal L., Orentas, Rimas J., Cheuk, Adam T., Khan, Javed

Source: In Cell Reports Medicine 21 May 2024 5(5)

A Conditionally Replicating HIV-1 Vector Interferes with Wild-Type HIV-1 Replication and Spread

Authors: Dropulić, Boro, Hěrmánková, Monika, Pitha, Paula M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1996 Oct 01. 93(20), 11103-11108.

Access URL: https://www.jstor.org/stable/40290

Reference standards for accurate validation and optimization of assays that determine integrated lentiviral vector copy number in transduced cells

Authors: Paugh, Barbara S., Baranyi, Lajos, Roy, Andre, He, Hua-Jun, Harris, Lindsay, Cole, Kenneth D., Artlip, Moria, Raimund, Caroline, Langan, Patricia S., Jana, Srikanta, Orentas, Rimas J., Lin-Gibson, Sheng, Krueger, Winfried, Dropulić, Boro

Source: Scientific reports. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191372668.0x000001&indx=1&recIds=ETOCvdc_100191372668.0x000001

Place-of-care manufacturing of gene therapies

Authors: Adair, Jennifer E, Anthony-Gonda, Kim, Bayigga, Lois, Orentas, Rimas, Mutuluuza, Cissy Kityo, Mathews, Vikram, Dropulić, Boro

Source: Lancet.Haematology. 9(11):e807-e808

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183779075.0x000001&indx=1&recIds=ETOCvdc_100183779075.0x000001

Circulating Tumor DNA Correlation with Lymphoma Response and Survival Outcomes at Multiple Time Points of Anti - CD19 CAR T Cell Therapy

Authors: Caimi, Paolo F, Di Trani, Martina ^*, Ghobadi, Armin, Reese, Jane ^*, Tomlinson, Benjamin, Otegbeye, Folashade, Boughan, Kirsten M, Gallogly, Molly, Metheny, Leland, Cooper, Brenda W., Dropulic, Boro ^*, de Lima, Marcos J.G., Carlo-Stella, Carmelo

Source: In Blood 15 November 2022 140 Supplement 1:7457-7459

Adjunct Therapy with T Regulatory Cells Decreases Inflammation and Preserves the Anti-Tumor Activity of CAR T Cells.

Authors: Zeng, Ke, Huang, Meixian, Lyu, Mi-Ae, Khoury, Joseph D., Ahmed, Sairah, Patel, Krina K., Dropulić, Boro, Reese-Koc, Jane, Caimi, Paolo F., Sadeghi, Tara, Lima, Marcos de, Flowers, Christopher R., Parmar, Simrit

Source: Cells (2073-4409); Jul2023, Vol. 12 Issue 14, p1880, 17p

Subject Terms: REGULATORY T cells, T cells, CHIMERIC antigen receptors, ANTINEOPLASTIC agents, ADULT respiratory distress syndrome, CORD blood, T cell receptors, KOUNIS syndrome

Lentiviral Vector Platform for Production of Bioengineered Recombinant Coagulation Factor VIII

Authors: Spencer, H Trent, Denning, Gabriela, Gautney, Richard E, Dropulic, Boro, Roy, Andre J, Baranyi, Lajos, Gangadharan, Bagirath, Parker, Ernest T, Lollar, Pete, Doering, Christopher B

Source: In Molecular Therapy February 2011 19(2):302-309

Gene Transfer in Humans Using a Conditionally Replicating Lentiviral Vector

Authors: Levine, Bruce L., Humeau, Laurent M., Boyer, Jean, MacGregor, Rob-Roy, Rebello, Tessio, Lu, Xiaobin, Binder, Gwendolyn K., Slepushkin, Vladimir, Lemiale, Franck, Mascola, John R., Bushman, Frederic D., Dropulic, Boro, June, Carl H.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2006 Nov . 103(46), 17372-17377.

Access URL: https://www.jstor.org/stable/30052439

Culture of Mouse Brain Capillary Endothelial Cell Lines That Express Factor VIII, γ-Glutamyl Transpeptidase, and Form Junctional Complexes in vitro

Authors: Dropulić, Boro, Masters, Colin L.

Source: In Vitro Cellular & Developmental Biology, 1987 Nov 01. 23(11), 775-781.

Access URL: https://www.jstor.org/stable/4296147

205 - Single Cell Cytokine Analysis of LV20.19 CAR T-Cells Expanded in IL-2 Versus IL-7 and IL-15

Authors: Zurko, Joanna, Xu, Huiqing, Chaney, Katherine, Fenske, Timothy S., Hamadani, Mehdi, Schneider, Dina, Dropulic, Boro, Hari, Parameswaran, Johnson, Bryon D, Shah, Nirav N.

Source: In Transplantation and Cellular Therapy March 2021 27(3) Supplement:S187-S189

Optimization of Lentiviral ß-Globin Vectors in a Forward Orientation to Enhance Therapeutic Effectiveness for Sickle Cell Disease

Authors: Okalova, Jennifer, Alexander, Jordan Shields, Chambliss, Christopher, Zhu, Zhongyu, Xie, Yanping, Addington-Hall, Matthew, Slessareva, Oxana, Luo, Tony, Ferencz, Beatrix, Oparaocha, Ibeawuchi, Uchida, Naoya, Tisdale, John F., Dropulic, Boro, Spencer, H. Trent, Orentas, Rimas J, Archer, David R

Source: In Blood 2 November 2023 142 Supplement 1:5002-5002

Inhibition of Simian/Human Immunodeficiency Virus Replication in CD4+ T Cells Derived from Lentiviral-Transduced CD34+ Hematopoietic Cells

Authors: Braun, Stephen E., Wong, Fay Eng, Connole, Michelle, Qiu, Gang, Lee, Lorrin, Gillis, Jackie, Lu, Xiaobin, Humeau, Laurent, Slepushkin, Vladimir, Binder, Gwendolyn K., Dropulic, Boro, Johnson, R. Paul

Source: In Molecular Therapy December 2005 12(6):1157-1167