In-vitro to in-vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmaco-dynamic models and a multiscale spatial-temporal liver twin

Authors: Dichamp, Jules, Cellière, Geraldine, Ghallab, Ahmed, Hassan, Reham, Boissier, Noemie, Hofmann, Ute, Reinders, Joerg, Sezgin, Selahaddin, Zühlke, Sebastian, Hengstler, Jan, Drasdo, Dirk

Subject Terms: Quantitative Biology - Tissues and Organs

Access URL: http://arxiv.org/abs/2210.08796

Automated Quantification of Amyloid Fibrils Morphological Features by Image Processing Techniques

Authors: Yin, Yi, Prigent, Stephanie, Torrent, Joan, Rezaei, Human, Drasdo, Dirk, Doumic, Marie

Source: 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019) Biomedical Imaging (ISBI 2019), 2019 IEEE 16th International Symposium on. :534-537 Apr, 2019

Relation: 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI)

Diffusion-weighted MRI-guided needle biopsies permit quantitative tumor heterogeneity assessment and cell load estimation

Authors: Yin, Yi, Breuhahn, Kai, Kauczor, Hans-Ulrich, Sedlaczek, Oliver, Vignon-Clementel, Irene E., Drasdo, Dirk

Subject Terms: Electrical Engineering and Systems Science - Image and Video Processing, Physics - Medical Physics

Access URL: http://arxiv.org/abs/2103.00714

Model predicts fundamental role of biomechanical control of cell cycle progression during liver regeneration after partial hepatectomy

Authors: Hoehme, Stefan, Gebhardt, Rolf, Hengstler, Jan G., Drasdo, Dirk

Subject Terms: Quantitative Biology - Tissues and Organs, Quantitative Biology - Cell Behavior

Access URL: http://arxiv.org/abs/2005.09151

Guided interactive image segmentation using machine learning and color based data set clustering

Authors: Friebel, Adrian, Johann, Tim, Drasdo, Dirk, Hoehme, Stefan

Subject Terms: Computer Science - Computer Vision and Pattern Recognition, Electrical Engineering and Systems Science - Image and Video Processing

Access URL: http://arxiv.org/abs/2005.07662

A liver digital twin for in silico testing of cellular and inter-cellular mechanisms in regeneration after drug-induced damage

Authors: Zhao, Jieling ^{1, 2}, Ghallab, Ahmed ^{1, 3}, Hassan, Reham ^{1, 3}, Dooley, Steven ⁴, Hengstler, Jan Georg ¹, Drasdo, Dirk ^{1, 2, 5, ∗}

Source: In iScience 16 February 2024 27(2)

An integrative experimental and computational twin modeling approach to understand clonal dynamics in the normal liver

Authors: Drasdo, Dirk, Zhao, Jieling

Source: Journal of hepatology. 79(2):273-276

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194208667.0x000001&indx=1&recIds=ETOCvdc_100194208667.0x000001

Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy

Authors: Hoehme, Stefan, Hammad, Seddik, Boettger, Jan, Begher-Tibbe, Brigitte, Bucur, Petru, Vibert, Eric, Gebhardt, Rolf, Hengstler, Jan G., Drasdo, Dirk

Source: In iScience 20 January 2023 26(1)

Tumor microvasculature in lung cancer and diffusion-weighted MRI: Preliminary results

Authors: Yin, Yi, Sedlaczek, Oliver, Lotz, Johannes, Olesch, Janine, Breuhahn, Kai, Drasdo, Dirk, Vignon-Clementel, Irene E.

Source: 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD), 2016. :1-3 Oct, 2016

Relation: 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)

Quantitative estimation of tumor cellularity based on histology data

Authors: Yin, Yi, Sedlaczek, Oliver, Warth, Arne, Gonzalez-Vallinas, Margarita, Breuhahn, Kai, Vignon-Clementel, Irene E., Drasdo, Dirk

Source: 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD), 2016. :1-3 Oct, 2016

Relation: 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)

System modeling of receptor-induced apoptosis

Authors: Bertaux, François, Drasdo, Dirk, Batt, Gregory

Source: Olivier Micheau. TRAIL, Fas Ligand, TNF and TLR3 in Cancer, 2017, Resistance to Targeted Anti-Cancer Therapeutics, 978-3-319-56804-1

Subject Terms: Quantitative Biology - Quantitative Methods, Quantitative Biology - Molecular Networks

Access URL: http://arxiv.org/abs/1712.06822

Guided interactive image segmentation using machine learning and color-based image set clustering

Authors: Friebel, Adrian, Johann, Tim, Drasdo, Dirk, Hoehme, Stefan

Source: Bioinformatics. 38(19):4622-4628

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165175852.0x000001&indx=1&recIds=ETOCvdc_100165175852.0x000001

On the Mechanisms of Biliary Flux

Authors: Vartak, Nachiket, Drasdo, Dirk, Geisler, Fabian, Itoh, Tohru, P.J.Oude Elferink, Ronald, Graaf, Stan F.J., Chiang, John, Keitel, Verena, Trauner, Michael, Jansen, Peter, Hengstler, Jan G.

Source: Hepatology. 74(6):3497-3512

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135784596.0x000001&indx=1&recIds=ETOCvdc_100135784596.0x000001

Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion‐Dominated Canalicular and Flow‐Augmented Ductular Bile Flux

Authors: Vartak, Nachiket, Guenther, Georgia, Joly, Florian, Damle‐Vartak, Amruta, Wibbelt, Gudrun, Fickel, Jörns, Jörs, Simone, Begher‐Tibbe, Brigitte, Friebel, Adrian, Wansing, Kasimir, Ghallab, Ahmed, Rosselin, Marie, Boissier, Noemie, Vignon‐Clementel, Irene, Hedberg, Christian, Geisler, Fabian, Hofer, Heribert, Jansen, Peter, Hoehme, Stefan, Drasdo, Dirk, Hengstler, Jan G.

Source: Hepatology. 73(4):1531-1550

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135390876.0x000001&indx=1&recIds=ETOCvdc_100135390876.0x000001

TiQuant: Software for tissue analysis, quantification and surface reconstruction

Authors: Friebel, Adrian, Neitsch, Johannes, Johann, Tim, Hammad, Seddik, Hengstler, Jan G., Drasdo, Dirk, Hoehme, Stefan

Subject Terms: Computer Science - Computational Engineering, Finance, and Science, Computer Science - Graphics, Quantitative Biology - Tissues and Organs

Access URL: http://arxiv.org/abs/1410.4598

Shape Characterization of Extracted and Simulated Tumor Samples using Topological and Geometric Measures

Authors: Rohrschneider, Markus, Scheuermann, Gerik, Hoehme, Stefan, Drasdo, Dirk

Source: 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE. :6271-6277 Aug, 2007

Relation: 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

A quantitative high-resolution computational mechanics cell model for growing and regenerating tissues

Authors: Van Liedekerke, Paul, Neitsch, Johannes, Johann, Tim, Warmt, Enrico, Gonzàlez-Valverde, Ismael, Hoehme, Stefan, Grosser, Steffen, Kaes, Josef, Drasdo, Dirk

Source: Biomechanics and modeling in mechanobiology. 19(1):189-220

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161857570.0x000001&indx=1&recIds=ETOCvdc_100161857570.0x000001

Generic growth instabilities in one-layered tissue sheets

Authors: Drasdo, Dirk

Subject Terms: Condensed Matter - Statistical Mechanics, Condensed Matter - Soft Condensed Matter, Physics - Biological Physics, Quantitative Biology

Access URL: http://arxiv.org/abs/cond-mat/9907208

Scaling Laws and Similarity Detection in Sequence Alignment with Gaps

Authors: Drasdo, Dirk, Hwa, Terence, Lassig, Michael

Subject Terms: Physics - Biological Physics, Condensed Matter - Statistical Mechanics, Quantitative Biology

Access URL: http://arxiv.org/abs/physics/9802023

3D digital histopathology: a new methodology for morphological characterization of the human liver

Authors: de Langlard, Mathieu, Trassard, Olivier, Antonietta, Messina, Benzoubir, Nassima, Dubart-Kupperschmitt, Anne, Duclos-Vallée, Jean-Charles, Guettier, Catherine, Vignon-Clementel, Irene, Drasdo, Dirk

Source: Journal of hepatology. 78(S1):S359-S360

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195508467.0x000001&indx=1&recIds=ETOCvdc_100195508467.0x000001