The interplay of TARG1 and PARG protects against genomic instability

Authors: Joséphine Groslambert, Evgeniia Prokhorova, Anne R. Wondisford, Callum Tromans-Coia, Celeste Giansanti, Jennifer Jansen, Gyula Timinszky, Matthias Dobbelstein, Dragana Ahel, Roderick J. O’Sullivan, Ivan Ahel

Source: Cell Reports, Vol 42, Iss 9, Pp 113113- (2023)

Subject Terms: CP: Molecular biology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723011245; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/b876a752cfb24b1990b0c4df1c0ffbba

ERCC6L2 mitigates replication stress and promotes centromere stability

Authors: Christopher J. Carnie, Lucy Armstrong, Marek Sebesta, Antonio Ariza, Xiaomeng Wang, Emily Graham, Kang Zhu, Dragana Ahel

Source: Cell Reports, Vol 42, Iss 4, Pp 112329- (2023)

Subject Terms: CP: Molecular biology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723003406; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/ce3976c83bf2446ba07dcf54342001a7

The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome

Authors: Ivo A. Hendriks, Sara C. Buch-Larsen, Evgeniia Prokhorova, Jonas D. Elsborg, Alexandra K.L.F.S. Rebak, Kang Zhu, Dragana Ahel, Claudia Lukas, Ivan Ahel, Michael L. Nielsen

Source: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/fe5e0ce471514232be42e096a42ca2cd

Serine-linked PARP1 auto-modification controls PARP inhibitor response

Authors: Evgeniia Prokhorova, Florian Zobel, Rebecca Smith, Siham Zentout, Ian Gibbs-Seymour, Kira Schützenhofer, Alessandra Peters, Joséphine Groslambert, Valentina Zorzini, Thomas Agnew, John Brognard, Michael L. Nielsen, Dragana Ahel, Sébastien Huet, Marcin J. Suskiewicz, Ivan Ahel

Source: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a461bc488c0d420bbd8c111fb3a6c0b4

Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal

Authors: Johannes Gregor Matthias Rack, Qiang Liu, Valentina Zorzini, Jim Voorneveld, Antonio Ariza, Kourosh Honarmand Ebrahimi, Julia M. Reber, Sarah C. Krassnig, Dragana Ahel, Gijsbert A. van der Marel, Aswin Mangerich, James S. O. McCullagh, Dmitri V. Filippov, Ivan Ahel

Source: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/4bbd22b00672441db09292221ae3ea22

Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential

Authors: Johannes Gregor Matthias Rack, Valentina Zorzini, Zihan Zhu, Marion Schuller, Dragana Ahel, Ivan Ahel

Source: Open Biology, Vol 10, Iss 11 (2020)

Subject Terms: (adp-ribosyl)hydrolase, alphavirus, antiviral poly(adp-ribosyl)polymerases, coronavirus, non-structural protein 3, x domain, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-2441

Access URL: https://doaj.org/article/7c1294537f4343e4bdc6ffb60634f073

Structural insights into the function of ZRANB3 in replication stress response

Authors: Marek Sebesta, Christopher D. O. Cooper, Antonio Ariza, Christopher J. Carnie, Dragana Ahel

Source: Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e255a9bc2f6248c5a18735606cd0c8fe