Pharmacokinetic assessment of low dose decitabine in combination therapies: Development and validation of a sensitive UHPLC-MS/MS method for murine plasma analysis

Authors: Anabtawi, Nadeen, Drabison, Thomas, Jin, Yan, Eisenmann, Eric D., Sparreboom, Alex, Govindarajan, Rajgopal, Baker, Sharyn D., Ahmed, Eman

Source: In Journal of Chromatography B 15 July 2024 1242

Vincristine Disposition and Neurotoxicity Are Unchanged in Humanized CYP3A5 Mice

Authors: Li, Yang, Kazuki, Yasuhiro, Drabison, Thomas, Kobayashi, Kaoru, Fujita, Ken-ichi, Xu, Yue, Jin, Yan, Ahmed, Eman, Li, Junan, Eisenmann, Eric D., Baker, Sharyn D., Cavaletti, Guido, Sparreboom, Alex, Hu, Shuiying ^*

Source: In Drug Metabolism and Disposition February 2024 52(2):80-85

The role of OATP1B1 and OATP1B3 transporter polymorphisms in drug disposition and response to anticancer drugs: a review of the recent literature

Authors: Anabtawi, Nadeen, Drabison, Thomas, Hu, Shuiying, Sparreboom, Alex, Talebi, Zahra

Source: Expert opinion on drug metabolism and toxicology. 18(7-8):459-468

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100160205167.0x000001&indx=1&recIds=ETOCvdc_100160205167.0x000001

Darolutamide does not interfere with OATP‐mediated uptake of docetaxel.

Authors: Buck, Stefan A. J., Talebi, Zahra, Drabison, Thomas, Jin, Yan, Gibson, Alice A., Hu, Peng, de Bruijn, Peter, de Ridder, Corrina M. A., Stuurman, Debra, Hu, Shuiying, van Weerden, Wytske M., Koolen, Stijn L. W., de Wit, Ronald, Sparreboom, Alex, Mathijssen, Ron H. J., Eisenmann, Eric D.

Source: International Journal of Cancer; Jul2024, Vol. 155 Issue 2, p314-323, 10p

Subject Terms: DOCETAXEL, ANDROGEN receptors, PROSTATE cancer patients, DRUG interactions

Strain- and Route-Dependent Plasma Pharmacokinetics and DRG Accumulation of Paclitaxel

Authors: Drabison, Thomas, Xu, Yue, Ahmed, Eman, Kandalai, Shruthi, Hoyt, Kari, Obrietan, Karl, Hu, Shuiying, Sparreboom, Alex, Eisenmann, Eric

Source: The Journal of Pharmacology and Experimental Therapeutics; June 2024, Vol. 389 Issue: 1, Number 1 Supplement 3 p259-259, 1p

Identification of Pazopanib as an OATP1B1 Substrate from a Competitive Counterflow Screen

Authors: Drabison, Thomas, Boeckman, Mike, Eisenmann, Eric, Baker, Sharyn D., Hu, Shuiying, Sparreboom, Alex, Talebi, Zahra

Source: The Journal of Pharmacology and Experimental Therapeutics; June 2023, Vol. 385 Issue: 1, Number 1 Supplement 3 p174-174, 1p

Contribution of CNT1 and CNT3 to the intestinal transport and pharmacokinetics of decitabine

Authors: Anabtawi, Nadeen, Drabison, Thomas, Boeckman, Mike, Jin, Yan, Halpin, Madeline, Gibson, Alice A., Sparreboom, Alex, Govindarajan, Raj, Baker, Sharyn D.

Source: The Journal of Pharmacology and Experimental Therapeutics; June 2023, Vol. 385 Issue: 1, Number 1 Supplement 3 p385-385, 1p