Toll-like receptor agonists as cancer vaccine adjuvants

Authors: Donghwan Jeon, Ethan Hill, Douglas G. McNeel

Source: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

Subject Terms: Toll-like receptors, cancer vaccines, vaccine adjuvants, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/2dfce16be56746b9bad9c4e2b77cea03

Long-term follow up of patients treated with a DNA vaccine (pTVG-hp) for PSA-recurrent prostate cancer

Authors: Tommaso P. Tonelli, Jens C. Eickhoff, Laura E. Johnson, Glenn Liu, Douglas G. McNeel

Source: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

Subject Terms: DNA vaccine, prostate cancer, prostatic acid phosphatase, long-term follow up, survival, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/f543448366ba4f7f81225df4f3929ccd

B cells require licensing by dendritic cells to serve as primary antigen-presenting cells for plasmid DNA

Authors: Ichwaku Rastogi, Douglas G. McNeel

Source: OncoImmunology, Vol 12, Iss 1 (2023)

Subject Terms: Antigen presentation, B cell, dendritic cell, DNA vaccine, plasmid DNA, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/af53b999f84b4843935a5e344743f9b2

Reversible epigenetic alterations regulate class I HLA loss in prostate cancer

Authors: Tamara S. Rodems, Erika Heninger, Charlotte N. Stahlfeld, Cole S. Gilsdorf, Kristin N. Carlson, Madison R. Kircher, Anupama Singh, Timothy E. G. Krueger, David J. Beebe, David F. Jarrard, Douglas G. McNeel, Michael C. Haffner, Joshua M. Lang

Source: Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/1153e9cc0b6a481e85909d4a3f28af7d

Toll-like receptor agonist combinations augment mouse T-cell anti-tumor immunity via IL-12- and interferon ß-mediated suppression of immune checkpoint receptor expression

Authors: Donghwan Jeon, Douglas G. McNeel

Source: OncoImmunology, Vol 11, Iss 1 (2022)

Subject Terms: Toll-like receptor, tumor vaccine, adjuvant, IL-12, type 1 interferon, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/e44df2bb140e4eebaf2c413aab136787

Role of B cells as antigen presenting cells

Authors: Ichwaku Rastogi, Donghwan Jeon, Jena E. Moseman, Anusha Muralidhar, Hemanth K. Potluri, Douglas G. McNeel

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: B cells, professional APC, antigen processing, antigen presentation, TIL-B, cellular therapies, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.954936/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/186693e6e8594177b96448fdb34d28e4

Targeted Radiation and Immune Therapies—Advances and Opportunities for the Treatment of Prostate Cancer

Authors: Anusha Muralidhar, Hemanth K. Potluri, Tanya Jaiswal, Douglas G. McNeel

Source: Pharmaceutics, Vol 15, Iss 1, p 252 (2023)

Subject Terms: combination therapy, radiation therapy, targeted radionuclide therapy, immunotherapy, prostate cancer, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/1/252; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/27dff2cf52724378a25bba05d8e4800f

PD-1 and LAG-3 blockade improve anti-tumor vaccine efficacy

Authors: Christopher D. Zahm, Jena E Moseman, Lauren E. Delmastro, Douglas G. Mcneel

Source: OncoImmunology, Vol 10, Iss 1 (2021)

Subject Terms: pd-1, lag-3, apc, tumor vaccine, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/78162b68b11746d59d937a79a9dce1cd

Infectious Tolerance as Seen With 2020 Vision: The Role of IL-35 and Extracellular Vesicles

Authors: Jeremy A. Sullivan, David P. AlAdra, Brian M. Olson, Douglas G. McNeel, William J. Burlingham

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: IL-35, extracellular vesicle, infectious tolerance, exosomes, immunotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.01867/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9bd64808cfef4ef380e337f25657c867

FLT PET/CT imaging of metastatic prostate cancer patients treated with pTVG-HP DNA vaccine and pembrolizumab

Authors: Matthew Scarpelli, Christopher Zahm, Scott Perlman, Douglas G. McNeel, Robert Jeraj, Glenn Liu

Source: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)

Subject Terms: FLT PET, Imaging, Cell proliferation, DNA vaccine, Pembrolizumab, Prostate cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40425-019-0516-1; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/ebe26695d09a424e9a4c3759d0b0ac91

Prime-boost vaccination targeting prostatic acid phosphatase (PAP) in patients with metastatic castration-resistant prostate cancer (mCRPC) using Sipuleucel-T and a DNA vaccine

Authors: Ellen Wargowski, Laura E. Johnson, Jens C. Eickhoff, Lauren Delmastro, Mary Jane Staab, Glenn Liu, Douglas G. McNeel

Source: Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-12 (2018)

Subject Terms: Sipuleucel-T, DNA vaccine, Prostate cancer, Prostatic acid phosphatase, Immune monitoring, Clinical trial, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40425-018-0333-y; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/af87872586dd4df4a01fa1683e476315

Pretreatment antigen-specific immunity and regulation - association with subsequent immune response to anti-tumor DNA vaccination

Authors: Laura E. Johnson, Brian M. Olson, Douglas G. McNeel

Source: Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-11 (2017)

Subject Terms: Biomarker, DNA vaccine, Prostatic acid phosphatase, Prostate cancer, Interleukin 10, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40425-017-0260-3; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/0c24ba68e7b7499d86b447cad96998b0

Heterologous vaccination targeting prostatic acid phosphatase (PAP) using DNA and Listeria vaccines elicits superior anti-tumor immunity dependent on CD4+ T cells elicited by DNA priming

Authors: Laura E. Johnson, Dirk Brockstedt, Meredith Leong, Peter Lauer, Erin Theisen, John-Demian Sauer, Douglas G. McNeel

Source: OncoImmunology, Vol 7, Iss 8 (2018)

Subject Terms: dna vaccine, heterologous prime-boost, listeria monocytogenes, prostatic acid phosphatase, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/4e7a46e148df47f2bda3f7e2f8cf6780

β-amino acid substitution in the SIINFEKL antigen alters immunological recognition

Authors: Ichwaku Rastogi, John A. Mannone, Ruslan Gibadullin, Jena E. Moseman, John Sidney, Alessandro Sette, Douglas G. McNeel, Samuel H. Gellman

Source: Cancer Biology & Therapy, Vol 26, Iss 1 (2025)

Subject Terms: Peptide vaccines, β-amino acid substitutions, proteolysis-resistant peptides, MHC I, CD8 T cells, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1538-4047; https://doaj.org/toc/1555-8576

Access URL: https://doaj.org/article/7e1e4cbe2ab142048d142439147f5934

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of prostate carcinoma

Authors: Daniel P. Petrylak, Lawrence Fong, Charles G. Drake, Mark N. Stein, Douglas G. McNeel, Ravi A. Madan, James L. Gulley, Neil H. Bander, Tomasz M. Beer, Stacey Harrelson, Philip W. Kantoff, William K. Oh, David J. Peace, Hank Porterfield, Oliver Sartor, Neal D. Shore, Susan F. Slovin, Johannes Vieweg

Source: Journal for ImmunoTherapy of Cancer, Vol 4, Iss 1 (2016)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/4/1/92.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/95b49601510e476591b41345b52e8b6d

Monitoring regulatory immune responses in tumor immunotherapy clinical trials

Authors: Brian M Olson, Douglas G. McNeel

Source: Frontiers in Oncology, Vol 3 (2013)

Subject Terms: Suppression, tolerance, regulatory T cells, myeloid-derived suppressor cells, immune monitoring, predictors of response, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00109/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/a7bdfe85dafa463cbb8d01075228418d

The SSX Family of Cancer-Testis Antigens as Target Proteins for Tumor Therapy

Authors: Heath A. Smith, Douglas G. McNeel

Source: Clinical and Developmental Immunology, Vol 2010 (2010)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1740-2522; https://doaj.org/toc/1740-2530

Access URL: https://doaj.org/article/483515e2b34345b08cdd92190d5a79d0

Identification of Antigen-Specific IgG in Sera from Patients with Chronic Prostatitis.

Authors: Edward J. Dunphy, Jens C. Eickhoff, Charles H. Muller, Richard E. Berger, Douglas G. McNeel

Source: Journal of Clinical Immunology; Sep2004, Vol. 24 Issue 5, p492-502, 11p

Sequence of androgen receptor-targeted vaccination with androgen deprivation therapy affects anti-prostate tumor efficacy

Authors: Douglas G McNeel, Melissa Gamat-Huber, Anusha Muralidhar, Sita Vakkalanka

Source: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/12/5/e008848.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/6ee9ae85e74447c8bc6ad9989ced5b16

Myeloid-derived suppressor cells attenuate the antitumor efficacy of radiopharmaceutical therapy using 90Y-NM600 in combination with androgen deprivation therapy in murine prostate tumors

Authors: Douglas G McNeel, Zachary S Morris, Reinier Hernandez, Jamey P Weichert, Anusha Muralidhar, Hansel Comas Rojas, Malick Bio Idrissou

Source: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/12/4/e008760.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/27673128e2c04b24a1157868424e0536