Druggable growth dependencies and tumor evolution analysis in patient-derived organoids of neuroendocrine neoplasms from multiple body sites

Authors: Dayton, Talya L., Alcala, Nicolas, Moonen, Laura, den Hartigh, Lisanne, Geurts, Veerle, Mangiante, Lise, Lap, Lisa, Dost, Antonella F.M., Beumer, Joep, Levy, Sonja, van Leeuwaarde, Rachel S., Hackeng, Wenzel M., Samsom, Kris, Voegele, Catherine, Sexton-Oates, Alexandra, Begthel, Harry, Korving, Jeroen, Hillen, Lisa, Brosens, Lodewijk A.A., Lantuejoul, Sylvie, Jaksani, Sridevi, Kok, Niels F.M., Hartemink, Koen J., Klomp, Houke M., Borel Rinkes, Inne H.M., Dingemans, Anne-Marie, Valk, Gerlof D., Vriens, Menno R., Buikhuisen, Wieneke, van den Berg, José, Tesselaar, Margot, Derks, Jules, Speel, Ernst Jan, Foll, Matthieu, Fernández-Cuesta, Lynnette, Clevers, Hans

Source: In Cancer Cell 11 December 2023 41(12):2083-2099

Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells

Authors: Dost, Antonella F.M., Moye, Aaron L., Vedaie, Marall, Tran, Linh M., Fung, Eileen, Heinze, Dar, Villacorta-Martin, Carlos, Huang, Jessie, Hekman, Ryan, Kwan, Julian H., Blum, Benjamin C., Louie, Sharon M., Rowbotham, Samuel P., Sainz de Aja, Julio, Piper, Mary E., Bhetariya, Preetida J., Bronson, Roderick T., Emili, Andrew, Mostoslavsky, Gustavo, Fishbein, Gregory A., Wallace, William D., Krysan, Kostyantyn, Dubinett, Steven M., Yanagawa, Jane, Kotton, Darrell N., Kim, Carla F.

Source: In Cell Stem Cell 1 October 2020 27(4):663-678