CREdb: A comprehensive database of Cis-Regulatory Elements and their activity in human cells and tissues

Authors: Chris Hartl, Jiali Zhuang, Aaron Tyler, Bing Zhou, Emily Wong, David Merberg, Brad Farrell, Chris DeBoever, Julie Bryant, Dorothée Diogo

Source: Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-8 (2024)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-8935

Access URL: https://doaj.org/article/e191238aa35e46acb3a8d97a4fa135b0

Assessing the potential of polygenic scores to strengthen medical risk prediction models of COVID-19.

Authors: Aldo Córdova-Palomera, Csaba Siffel, Chris DeBoever, Emily Wong, Dorothée Diogo, Sandor Szalma

Source: PLoS ONE, Vol 18, Iss 5, p e0285991 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/663871508a21485f87cbeab03a515768

Phenome-wide association studies across large population cohorts support drug target validation

Authors: Dorothée Diogo, Chao Tian, Christopher S. Franklin, Mervi Alanne-Kinnunen, Michael March, Chris C. A. Spencer, Ciara Vangjeli, Michael E. Weale, Hannele Mattsson, Elina Kilpeläinen, Patrick M. A. Sleiman, Dermot F. Reilly, Joshua McElwee, Joseph C. Maranville, Arnaub K. Chatterjee, Aman Bhandari, Khanh-Dung H. Nguyen, Karol Estrada, Mary-Pat Reeve, Janna Hutz, Nan Bing, Sally John, Daniel G. MacArthur, Veikko Salomaa, Samuli Ripatti, Hakon Hakonarson, Mark J. Daly, Aarno Palotie, David A. Hinds, Peter Donnelly, Caroline S. Fox, Aaron G. Day-Williams, Robert M. Plenge, Heiko Runz

Source: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/cb9fc601268446ca86cfc25a436b40c6

Gene flow contributes to diversification of the major fungal pathogen Candida albicans

Authors: Jeanne Ropars, Corinne Maufrais, Dorothée Diogo, Marina Marcet-Houben, Aurélie Perin, Natacha Sertour, Kevin Mosca, Emmanuelle Permal, Guillaume Laval, Christiane Bouchier, Laurence Ma, Katja Schwartz, Kerstin Voelz, Robin C. May, Julie Poulain, Christophe Battail, Patrick Wincker, Andrew M. Borman, Anuradha Chowdhary, Shangrong Fan, Soo Hyun Kim, Patrice Le Pape, Orazio Romeo, Jong Hee Shin, Toni Gabaldon, Gavin Sherlock, Marie-Elisabeth Bougnoux, Christophe d’Enfert

Source: Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/df686121e41b41bbbac4e0c33f4eb781

The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1.

Authors: Gang Li, Pierre Cunin, Di Wu, Dorothée Diogo, Yu Yang, Yukinori Okada, Robert M Plenge, Peter A Nigrovic

Source: PLoS Genetics, Vol 12, Iss 9, p e1006292 (2016)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5023119?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/ee0b89fcf67541abbb35cd0c8706354f

TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.

Authors: Dorothée Diogo, Lisa Bastarache, Katherine P Liao, Robert R Graham, Robert S Fulton, Jeffrey D Greenberg, Steve Eyre, John Bowes, Jing Cui, Annette Lee, Dimitrios A Pappas, Joel M Kremer, Anne Barton, Marieke J H Coenen, Barbara Franke, Lambertus A Kiemeney, Xavier Mariette, Corrine Richard-Miceli, Helena Canhão, João E Fonseca, Niek de Vries, Paul P Tak, J Bart A Crusius, Michael T Nurmohamed, Fina Kurreeman, Ted R Mikuls, Yukinori Okada, Eli A Stahl, David E Larson, Tracie L Deluca, Michelle O'Laughlin, Catrina C Fronick, Lucinda L Fulton, Roman Kosoy, Michael Ransom, Tushar R Bhangale, Ward Ortmann, Andrew Cagan, Vivian Gainer, Elizabeth W Karlson, Isaac Kohane, Shawn N Murphy, Javier Martin, Alexandra Zhernakova, Lars Klareskog, Leonid Padyukov, Jane Worthington, Elaine R Mardis, Michael F Seldin, Peter K Gregersen, Timothy Behrens, Soumya Raychaudhuri, Joshua C Denny, Robert M Plenge

Source: PLoS ONE, Vol 10, Iss 4, p e0122271 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4388675?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/beb6d79c3e184701a89299ca92e0df4f

Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway.

Authors: Gang Li, Dorothée Diogo, Di Wu, Jim Spoonamore, Vlado Dancik, Lude Franke, Fina Kurreeman, Elizabeth J Rossin, Grant Duclos, Cathy Hartland, Xuezhong Zhou, Kejie Li, Jun Liu, Philip L De Jager, Katherine A Siminovitch, Alexandra Zhernakova, Soumya Raychaudhuri, John Bowes, Steve Eyre, Leonid Padyukov, Peter K Gregersen, Jane Worthington, Rheumatoid Arthritis Consortium International (RACI), Namrata Gupta, Paul A Clemons, Eli Stahl, Nicola Tolliday, Robert M Plenge

Source: PLoS Genetics, Vol 9, Iss 5, p e1003487 (2013)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3656093?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/603abdaa6bb84998953d03c9d0b32fa5

Quantifying missing heritability at known GWAS loci.

Authors: Alexander Gusev, Gaurav Bhatia, Noah Zaitlen, Bjarni J Vilhjalmsson, Dorothée Diogo, Eli A Stahl, Peter K Gregersen, Jane Worthington, Lars Klareskog, Soumya Raychaudhuri, Robert M Plenge, Bogdan Pasaniuc, Alkes L Price

Source: PLoS Genetics, Vol 9, Iss 12, p e1003993 (2013)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3873246?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/9993d2512a404b03bdb0dac3d986201c

A versatile overexpression strategy in the pathogenic yeast Candida albicans: identification of regulators of morphogenesis and fitness.

Authors: Murielle Chauvel, Audrey Nesseir, Vitor Cabral, Sadri Znaidi, Sophie Goyard, Sophie Bachellier-Bassi, Arnaud Firon, Mélanie Legrand, Dorothée Diogo, Claire Naulleau, Tristan Rossignol, Christophe d'Enfert

Source: PLoS ONE, Vol 7, Iss 9, p e45912 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3457969?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/66700dc5d0144f9b9f516db41f8c8b36

Sleep apnoea is a risk factor for severe COVID-19

Authors: Riitta Kaarteenaho, Nina Hautala, Athena Matakidou, Jaakko Kaprio, Ying Wu, Kai Kaarniranta, Peeter Karihtala, Kari Pulkki, Wei Zhou, Caroline Fox, Jussi Pihlajamäki, Apinya Lertratanakul, Juha Paloneva, Johannes Kettunen, Marita Kalaoja, Markus Perola, Veikko Salomaa, Hilkka Soininen, Mika Kähönen, Hao Chen, Andrey Loboda, Soumitra Ghosh, Anders Mälarstig, Markku Laakso, Marja Luodonpää, Markus Juonala, Xing Chen, Marika Crohns, Juhani Junttila, Sirkku Peltonen, Keith Usiskin, Juha Sinisalo, Aarno Palotie, Samuli Ripatti, Oili Kaipiainen-Seppänen, Aki Havulinna, Satu Strausz, Tuomo Kiiskinen, Martin Broberg, Sanni Ruotsalainen, Jukka Koskela, Tuula Palotie, Hanna M. Ollila, Mark Daly, Howard Jacob, Heiko Runz, Sally John, Robert Plenge, Mark McCarthy, Julie Hunkapiller, Meg Ehm, Dawn Waterworth, Kathy Klinger, Kathy Call, Tomi Mäkelä, Petri Virolainen, Terhi Kilpi, Jukka Partanen, Anne Pitkäranta, Seppo Vainio, Kimmo Savinainen, Veli-Matti Kosma, Urho Kujala, Outi Tuovila, Minna Hendolin, Raimo Pakkanen, Jeff Waring, States Bridget Riley-Gillis, Jimmy Liu, Shameek Biswas, Dorothee Diogo, Anders Pfizer, Catherine Marshall, Matthias Gossel, Johanna Schleutker, Mikko Arvas, Olli Carpen, Reetta Hinttala, Reijo Laaksonen, Arto Mannermaa, Valtteri Julkunen, Anne Remes, Reetta Kälviäinen, Mikko Hiltunen, Jukka Peltola, Pentti Tienari, Juha Rinne, Adam Ziemann, Jeffrey Waring, Sahar Esmaeeli, Nizar Smaoui, Anne Lehtonen, Susan Eaton, Sanni Lahdenperä, John Michon, Geoff Kerchner, Natalie Bowers, Edmond Teng, John Merck, Vinay Mehta, Padhraig Gormley, Kari Linden, Christopher Whelan, Fanli Xu, David Pulford, Martti Färkkilä, Sampsa Pikkarainen, Airi Jussila, Timo Blomster, Mikko Kiviniemi, Markku Voutilainen, Bob Georgantas, Graham Heap, Fedik Rahimov, Joseph Maranville, Tim Lu, Danny Oh, Kirsi Kalpala, Melissa Miller, Linda McCarthy, Kari Eklund, Antti Palomäki, Pia Isomäki, Laura Pirilä, Johanna Huhtakangas, David Close, Marla Hochfeld, Nan Bing, Jorge Esparza Gordillo, Nina Mars, Tarja Laitinen, Margit Pelkonen, Paula Kauppi, Hannu Kankaanranta, Terttu Harju, Steven GreenbergCelgene, Hubert Chen, Jo Betts, Teemu Niiranen, Kaj Metsärinne, Marja-Riitta Taskinen, Tiinamaija Tuomi, Jari Laukkanen, Andrew Peterson Ben Challis, Audrey Chu, Jaakko Parkkinen, Anthony Muslin, Heikki Joensuu, Tuomo Meretoja, Lauri Aaltonen, Annika Auranen, Saila Kauppila, Päivi Auvinen, Klaus Elenius, Relja Popovic, Bridget Riley-Gillis, Jennifer Schutzman, Aparna Chhibber, Heli Lehtonen, Stefan McDonough, Diptee Kulkarni, Joni Turunen, Terhi Ollila, Sanna Seitsonen, Hannu Uusitalo, Vesa Aaltonen, Hannele Uusitalo-Järvinen, Erich Strauss, Anna Podgornaia, Joshua Hoffman, Kaisa Tasanen, Laura Huilaja, Katariina Hannula-Jouppi, Teea Salmi, Leena Koulu, Ilkka Harvima, David Choy, Anu Jalanko, Risto Kajanne, Ulrike Lyhs, Mari Kaunisto, Justin Davis, Danjuma Quarless, Slavé Petrovski, Chia-Yen Chen, Paola Bronson, Robert Yang, Diana Chang, Tushar Bhangale, Emily Holzinger, Xulong Wang, Åsa Hedman, Kirsi Auro, Clarence Wang, Ethan Xu, Franck Auge, Clement Chatelain, Mitja Kurki, Juha Karjalainen, Kimmo Palin, Priit Palta, Pietro Della, Susanna Lemmelä, Manuel Rivas, Jarmo Harju, Arto Lehisto, Andrea Ganna, Vincent Llorens, Antti Karlsson, Kati Kristiansson, Kati Hyvärinen, Jarmo Ritari, Tiina Wahlfors, Miika Koskinen, Katri Pylkäs, Minna Karjalainen, Tuomo Mantere, Eeva Kangasniemi, Sami Heikkinen, Eija Laakkonen, Juha Kononen, Anu Loukola, Päivi Laiho, Tuuli Sistonen, Essi Kaiharju, Markku Laukkanen, Elina Järvensivu, Sini Lähteenmäki, Lotta Männikkö, Regis Wong, Hannele Mattsson, Tero Hiekkalinna, Manuel Jiménez, Kati Donner, Kalle Pärn, Javier Nunez-Fontarnau, Elina Kilpeläinen, Timo Sipilä, Georg Brein, Alexander Dada, Ghazal Awaisa, Anastasia Shcherban, Tuomas Sipilä, Hannele Laivuori, Harri Siirtola, Javier Tabuenca, Lila Kallio, Sirpa Soini, Kimmo Pitkänen, Teijo Kuopio

Source: BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)

Subject Terms: Medicine, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://bmjopenrespres.bmj.com/content/8/1/e000845.full; https://doaj.org/toc/2052-4439

Access URL: https://doaj.org/article/665d58ff79f64fd48408e3fae6e27c75

Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene.

Authors: Yukinori Okada, Dorothee Diogo, Jeffrey D Greenberg, Faten Mouassess, Walid A L Achkar, Robert S Fulton, Joshua C Denny, Namrata Gupta, Daniel Mirel, Stacy Gabriel, Gang Li, Joel M Kremer, Dimitrios A Pappas, Robert J Carroll, Anne E Eyler, Gosia Trynka, Eli A Stahl, Jing Cui, Richa Saxena, Marieke J H Coenen, Henk-Jan Guchelaar, Tom W J Huizinga, Philippe Dieudé, Xavier Mariette, Anne Barton, Helena Canhão, João E Fonseca, Niek de Vries, Paul P Tak, Larry W Moreland, S Louis Bridges, Corinne Miceli-Richard, Hyon K Choi, Yoichiro Kamatani, Pilar Galan, Mark Lathrop, Towfique Raj, Philip L De Jager, Soumya Raychaudhuri, Jane Worthington, Leonid Padyukov, Lars Klareskog, Katherine A Siminovitch, Peter K Gregersen, Elaine R Mardis, Thurayya Arayssi, Layla A Kazkaz, Robert M Plenge

Source: PLoS ONE, Vol 9, Iss 2, p e87645 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3919745?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/2190887409354955965ee70f47ab4ea7

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.

Authors: Jing Cui, Eli A Stahl, Saedis Saevarsdottir, Corinne Miceli, Dorothee Diogo, Gosia Trynka, Towfique Raj, Maša Umiċeviċ Mirkov, Helena Canhao, Katsunori Ikari, Chikashi Terao, Yukinori Okada, Sara Wedrén, Johan Askling, Hisashi Yamanaka, Shigeki Momohara, Atsuo Taniguchi, Koichiro Ohmura, Fumihiko Matsuda, Tsuneyo Mimori, Namrata Gupta, Manik Kuchroo, Ann W Morgan, John D Isaacs, Anthony G Wilson, Kimme L Hyrich, Marieke Herenius, Marieke E Doorenspleet, Paul-Peter Tak, J Bart A Crusius, Irene E van der Horst-Bruinsma, Gert Jan Wolbink, Piet L C M van Riel, Mart van de Laar, Henk-Jan Guchelaar, Nancy A Shadick, Cornelia F Allaart, Tom W J Huizinga, Rene E M Toes, Robert P Kimberly, S Louis Bridges, Lindsey A Criswell, Larry W Moreland, João Eurico Fonseca, Niek de Vries, Barbara E Stranger, Philip L De Jager, Soumya Raychaudhuri, Michael E Weinblatt, Peter K Gregersen, Xavier Mariette, Anne Barton, Leonid Padyukov, Marieke J H Coenen, Elizabeth W Karlson, Robert M Plenge

Source: PLoS Genetics, Vol 9, Iss 3, p e1003394 (2013)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3610685?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/81c1f31b39334e34b1f84c06c37997b4