Small-molecule-induced ERBB4 activation to treat heart failure

Authors: Julie M. T. Cools, Bo K. Goovaerts, Eline Feyen, Siel Van den Bogaert, Yile Fu, Céline Civati, Jens Van fraeyenhove, Michiel R. L. Tubeeckx, Jasper Ott, Long Nguyen, Eike M. Wülfers, Benji Van Berlo, Antoine A. F. De Vries, Nele Vandersickel, Daniël A. Pijnappels, Dominique Audenaert, H. Llewelyn Roderick, Hans De Winter, Gilles W. De Keulenaer, Vincent F. M. Segers

Source: Nature Communications, Vol 16, Iss 1, Pp 1-19 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e8e46c0841a143a99b316fc5a47e03d8

The novel family of Warbicin® compounds inhibits glucose uptake both in yeast and human cells and restrains cancer cell proliferation

Authors: Ward Vanthienen, Juan Fernández-García, Maria Francesca Baietti, Elisa Claeys, Frederik Van Leemputte, Long Nguyen, Vera Goossens, Quinten Deparis, Dorien Broekaert, Sophie Vlayen, Dominique Audenaert, Michel Delforge, Alessandro D’Amuri, Griet Van Zeebroeck, Eleonora Leucci, Sarah-Maria Fendt, Johan M. Thevelein

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: glucose uptake, yeast, cancer cells, Warburg effect, transport-associated phosphorylation, synthetic inhibitors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1411983/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/a8c6508b076646c7a024f4d85755eb93

Nitrate and ammonium, the yin and yang of nitrogen uptake: a time-course transcriptomic study in rice

Authors: Pierre-Mathieu Pélissier, Boris Parizot, Letian Jia, Alexa De Knijf, Vera Goossens, Pascal Gantet, Antony Champion, Dominique Audenaert, Wei Xuan, Tom Beeckman, Hans Motte

Source: Frontiers in Plant Science, Vol 15 (2024)

Subject Terms: transcriptome, rice, co-expression network, nitrogen, OsRLI1, OsEIL1, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpls.2024.1343073/full; https://doaj.org/toc/1664-462X

Access URL: https://doaj.org/article/4e32fc33cab843a2a80957a141bffbbe

Local structural preferences in shaping tau amyloid polymorphism

Authors: Nikolaos Louros, Martin Wilkinson, Grigoria Tsaka, Meine Ramakers, Chiara Morelli, Teresa Garcia, Rodrigo Gallardo, Sam D’Haeyer, Vera Goossens, Dominique Audenaert, Dietmar Rudolf Thal, Ian R. Mackenzie, Rosa Rademakers, Neil A. Ranson, Sheena E. Radford, Frederic Rousseau, Joost Schymkowitz

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f3710df2103c4621bd7f36ca9c11b864

High-throughput assays to identify archaea-targeting nitrification inhibitors

Authors: Fabian Beeckman, Andrzej Drozdzecki, Alexa De Knijf, Dominique Audenaert, Tom Beeckman, Hans Motte

Source: Frontiers in Plant Science, Vol 14 (2024)

Subject Terms: nitrification inhibitors, Nitrososphaera viennensis, high-throughput (HT) screening, ammonia-oxidizing archaea, nitrifying community, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpls.2023.1283047/full; https://doaj.org/toc/1664-462X

Access URL: https://doaj.org/article/0b53948be9fd44f58083562aefe3f8b4

Systematic optimization of Cas12a base editors in wheat and maize using the ITER platform

Authors: Christophe Gaillochet, Alexandra Peña Fernández, Vera Goossens, Katelijn D’Halluin, Andrzej Drozdzecki, Myriam Shafie, Julie Van Duyse, Gert Van Isterdael, Camila Gonzalez, Mattias Vermeersch, Jonas De Saeger, Ward Develtere, Dominique Audenaert, David De Vleesschauwer, Frank Meulewaeter, Thomas B. Jacobs

Source: Genome Biology, Vol 24, Iss 1, Pp 1-24 (2023)

Subject Terms: CRISPR, Plant biotechnology, High-content imaging, Cas9, Cas12a, Base editing, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/d60860646d364899b3c553584e14290c

Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers

Authors: Nikolaos Louros, Meine Ramakers, Emiel Michiels, Katerina Konstantoulea, Chiara Morelli, Teresa Garcia, Nele Moonen, Sam D’Haeyer, Vera Goossens, Dietmar Rudolf Thal, Dominique Audenaert, Frederic Rousseau, Joost Schymkowitz

Source: Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e15b998d4cc744bfad75519cf5ead39e

Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidification

Authors: Wim Dejonghe, Sabine Kuenen, Evelien Mylle, Mina Vasileva, Olivier Keech, Corrado Viotti, Jef Swerts, Matyáš Fendrych, Fausto Andres Ortiz-Morea, Kiril Mishev, Simon Delang, Stefan Scholl, Xavier Zarza, Mareike Heilmann, Jiorgos Kourelis, Jaroslaw Kasprowicz, Le Son Long Nguyen, Andrzej Drozdzecki, Isabelle Van Houtte, Anna-Mária Szatmári, Mateusz Majda, Gary Baisa, Sebastian York Bednarek, Stéphanie Robert, Dominique Audenaert, Christa Testerink, Teun Munnik, Daniël Van Damme, Ingo Heilmann, Karin Schumacher, Johan Winne, Jiří Friml, Patrik Verstreken, Eugenia Russinova

Source: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/50a7efdd53054d58bdc66c48775ef3ba

De novo SCN1A mutations are a major cause of severe myoclonic epilepsy of infancy(Communicated by Jacques S. Beckmann).

Authors: Lieve Claes, Berten Ceulemans, Dominique Audenaert, Katrien Smets, Ann Löfgren, Jurgen Del-Favero, Sirpa Ala-Mello, Lina Basel-Vanagaite, Barbara Plecko, Salmo Raskin, Paul Thiry, Nicole I. Wolf, Christine Van Broeckhoven

Source: Human Mutation; Jun2003, Vol. 21 Issue 6, p615, 7p

Subject Terms: MYOCLONUS, EPILEPSY, JUVENILE diseases, SEIZURES (Medicine), GENETIC mutation

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