Data from French named patient program of quizartinib in relapsed/refractory acute myeloid leukemia

Authors: Fodil, S., Raffoux, E., Dumas, P. Y., Desbrosses, Y., Larosa, F., Chantepie, S., Larcher, M. V., Mear, J. B., Peterlin, P., Hunault-Berger, M., Hospital, M. A., Morel, V., Lucas, N., Vidal, V., Salanoubat, C., Michel, J., Mediavilla, C., Ojeda-Uribe, M., Alexis, M., Frayfer, J., Carré, M., Maillard, N., Redjoul, R., Banos, A., Detrait, M., Cluzeau, T., Wickenhauser, S., Chaoui, D., Elassy, M., Pigneux, A., Dombret, H., Récher, C., Bertoli, S.

Source: Leukemia & lymphoma. 62(7):1756-1760

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123447001.0x000001&indx=1&recIds=ETOCvdc_100123447001.0x000001

Acute lymphoblastic leukaemia in adult patients: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Authors: Hoelzer, D. ¹, Bassan, R. ², Dombret, H. ³, Fielding, A. ⁴, Ribera, J.M. ⁵, Buske, C. ⁶

Source: In Annals of Oncology September 2016 27 Supplement 5:v69-v82

Hypomethylating Agents as a Therapy for AML

Authors: Gardin, C., Dombret, H.

Source: CURRENT HEMATOLOGIC MALIGNANCY REPORTS. 12(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN383473559&indx=1&recIds=ETOCRN383473559

Acute Lymphoblastic Leukemia in Adolescents and Young Adults: Is the Treatment Paradigm Changing?
American Society of Clinical Oncology

Authors: Huguet, F., Boissel, N., Dombret, H.

Source: AMERICAN SOCIETY OF CLINICAL ONCOLOGY EDUCATIONAL BOOK. 45:360-364

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN077819458&indx=1&recIds=ETOCCN077819458

P498: CLINICAL AND BIOLOGICAL MARKERS ASSOCIATED WITH LONG-TERM SURVIVAL FOR PATIENTS WITH ACUTE MYELOID LEUKEMIA (AML) IN REMISSION AFTER CHEMOTHERAPY IN THE QUAZAR AML-001 TRIAL OF ORAL AZACITIDINE

Authors: Wei, A. H., Döhner, H., Sayar, H., Ravandi, F., Montesinos, P., Dombret, H., Selleslag, D., Porkka, K., Jang, J.-H., Skikne, B., Beach, C., Prebet, T., Zhang, G., Risueño, A., Ugidos Guerrero, M., See, W. L., Menezes, D., Roboz, G. J.

Source: HemaSphere. 6:397-398

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165725826.0x000001&indx=1&recIds=ETOCvdc_100165725826.0x000001

P404: PROGNOSTIC IMPACT OF CEBPA-MUTATIONAL SUBGROUPS IN ADULT AML – RESULTS OF A LARGE METAANALYSIS IN MORE THAN 1000 CEBPA-MUTANT PATIENTS

Authors: Georgi, J.-A., Stasik, S., Kramer, M., Röllig, C., Haferlach, T., Valk, P., Linch, D., Herold, T., Duployez, N., Taube, F., Platzbecker, U., Serve, H., Baldus, C., Müller-Tidow, C., Haferlach, C., Meggendorfer, M., Koch, S., Boertjes, E. L., Hills, R. K., Burnett, A., Ehninger, G., Metzeler, K., Rothenberg-Thurley, M., Dufour, A., Dombret, H., Pautas, C., Fenwarth, L., Bornhäuser, M., Gale, R., Thiede, C.

Source: HemaSphere. 6:304-305

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165724046.0x000001&indx=1&recIds=ETOCvdc_100165724046.0x000001

S130: NPM1 MUTATED AML: IMPACT OF CO-MUTATIONAL PATTERNS - RESULTS OF THE EUROPEAN HARMONY ALLIANCE

Authors: Hernández-Sánchez, A., Villaverde-Ramiro, Á., Martínez Elicegui, J., González, T., Benner, A., Sträng, E., Castellani, G., Heckman, C. A., Versluis, J., Abáigar, M., Sobas, M., Azibeiro, R., Tur, L., Valk, P. J., Metzeler, K. H., Ayala, R., Dall'Olio, D., Tettero, J., Martínez-López, J., Dombret, H., Pratcorona, M., Damm, F., Mills, K. I., Mayer, J., Thiede, C., Voso, M. T., Sanz, G. F., Calado, F., Döhner, K., Gaidzik, V. I., Heuser, M., Haferlach, T., Turki, A. T., Reinhardt, D., Villoria Medina, R., van Speybroeck, M., Schulze-Rath, R., Barbus, M., Butler, J. E., Hernández Rivas, J. M., Huntly, B. J., Ossenkoppele, G. J., Döhner, H., Bullinger, L.

Source: HemaSphere. 6:31-32

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S100: QUIZARTINIB PROLONGED SURVIVAL VS PLACEBO PLUS INTENSIVE INDUCTION AND CONSOLIDATION THERAPY FOLLOWED BY SINGLE-AGENT CONTINUATION IN PATIENTS AGED 18-75 YEARS WITH NEWLY DIAGNOSED FLT3-ITD+ AML

Authors: Erba, H., Montesinos, P., Vrhovac, R., Patkowska, E., Kim, H.-J., Zak, P., Wang, P.-N., Mitov, T., Hanyok, J., Liu, L., Benzohra, A., Lesegretain, A., Cortes, J., Perl, A., Sekeres, M., Dombret, H., Amadori, S., Wang, J., Levis, M., Schlenk, R.

Source: HemaSphere. 6:1-2

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165721762.0x000001&indx=1&recIds=ETOCvdc_100165721762.0x000001

PB1762: PONATINIB VERSUS IMATINIB WITH REDUCED-INTENSITY CHEMOTHERAPY IN PATIENTS WITH NEWLY DIAGNOSED PHILADELPHIA CHROMOSOME–POSITIVE (PH+) ACUTE LYMPHOBLASTIC LEUKEMIA (ALL): PHALLCON STUDY

Authors: Jabbour, E., Martinelli, G., Vignetti, M., Kantarjian, H., Gomez-Almaguer, D., Minami, Y., Dombret, H., Hennessy, M., Vorog, A., Wang, B., Ribera, J.-M.

Source: HemaSphere. 6:1643-1644

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P374: BLINATUMOMAB AS CONSOLIDATION FOR ADULT B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA. A REAL-WORLD STUDY

Authors: Urbino, I., Lengline, E., Cerrano, M., Rabian, F., Kim, R., Sebert, M., Itzykson, R., Audisio, E., Ades, L., Dombret, H., Raffoux, E., Ferrero, D., Clappier, E., Boissel, N.

Source: HemaSphere. 6:274-275

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165708965.0x000001&indx=1&recIds=ETOCvdc_100165708965.0x000001

Usefulness of the 2012 European CVD risk assessment model to identify patients at high risk of cardiovascular events during nilotinib therapy in chronic myeloid leukemia

Authors: Rea, D, Mirault, T, Raffoux, E, Boissel, N, Andreoli, A L, Rousselot, P, Dombret, H, Messas, E

Source: Leukemia. 29(5):1206-1209

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194150759.0x000001&indx=1&recIds=ETOCvdc_100194150759.0x000001

HLA-matched allogeneic stem cell transplantation improves outcome of higher risk myelodysplastic syndrome A prospective study on behalf of SFGM-TC and GFM

Authors: Robin, M, Porcher, R, Adès, L, Raffoux, E, Michallet, M, François, S, Cahn, J-Y, Delmer, A, Wattel, E, Vigouroux, S, Bay, J-O, Cornillon, J, Huynh, A, Nguyen, S, Rubio, M-T, Vincent, L, Maillard, N, Charbonnier, A, de Latour, R P, Reman, O, Dombret, H, Fenaux, P, Socié, G

Source: Leukemia. 29(7):1496-1501

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194149677.0x000001&indx=1&recIds=ETOCvdc_100194149677.0x000001

Liposomal cytarabine in prophylaxis or curative treatment of central nervous system involvement in Burkitt leukemia/lymphoma

Authors: Segot, A., Raffoux, E., Lengline, E., Thieblemont, C., Dombret, H., Boissel, N., Cluzeau, T.

Source: ANNALS OF HEMATOLOGY. 94(11):1859-1863

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN373048341&indx=1&recIds=ETOCRN373048341

Clofarabine for the treatment of adult acute lymphoid leukemia: the Group for Research on Adult Acute Lymphoblastic Leukemia intergroup

Authors: Huguet, F., Leguay, T., Raffoux, E., Rousselot, P., Vey, N., Pigneux, A., Ifrah, N., Dombret, H.

Source: LEUKEMIA AND LYMPHOMA. 56(4):847-857

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Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study

Authors: Topp, M. S., Gökbuget, N., Stein, A. S., Zugmaier, G., OBrien, S., Bargou, R. C., Dombret, H., Fielding, A. K., Heffner, L., Larson, R. A.

Source: LANCET ONCOLOGY. 16(1):57-66

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Improving results of autologous stem cell transplantation for Philadelphia-positive acute lymphoblastic leukaemia in the era of tyrosine kinase inhibitors: A report from the Acute Leukaemia Working Party of the European Group for Blood and Marrow Transplantation

Authors: Giebel, S., Labopin, M., Gorin, N.C., Caillot, D., Leguay, T., Schaap, N., Michallet, M., Dombret, H., Mohty, M.

Source: EUROPEAN JOURNAL OF CANCER -A-. 50(2):411-417

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN362637130&indx=1&recIds=ETOCRN362637130

Acute myeloid leukemia impairs natural killer cells through the formation of a deficient cytotoxic immunological synapse

Authors: Khaznadar, Z., Henry, G., Setterblad, N., Agaugue, S., Raffoux, E., Boissel, N., Dombret, H., Toubert, A., Dulphy, N.

Source: EUROPEAN JOURNAL OF IMMUNOLOGY. 44(10):3068-3080

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Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials

Authors: Hills, R. K., Castaigne, S., Appelbaum, F. R., Delaunay, J., Petersdorf, S., Othus, M., Estey, E. H., Dombret, H., Chevret, S., Ifrah, N.

Source: LANCET ONCOLOGY. 15(9):986-996

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN356800702&indx=1&recIds=ETOCRN356800702

Pediatric-Like Therapy for Adults with ALL

Authors: Dombret, H., Cluzeau, T., Huguet, F. o., Boissel, N.

Source: CURRENT HEMATOLOGIC MALIGNANCY REPORTS. 9(2):158-164

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN353605675&indx=1&recIds=ETOCRN353605675

Contribution of CD39 to the immunosuppressive microenvironment of acute myeloid leukaemia at diagnosis

Authors: Dulphy, N., Henry, G., Hemon, P., Khaznadar, Z., Dombret, H., Boissel, N., Bensussan, A., Toubert, A.

Source: BRITISH JOURNAL OF HAEMATOLOGY. 165(5):722-725

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN353127159&indx=1&recIds=ETOCRN353127159