Aberrant redox biology and epigenetic reprogramming: Co-conspirators across multiple human diseases

Authors: Domann, Frederick E., Hitchler, Michael J.

Source: In Free Radical Biology and Medicine July 2021 170:2-5

The epigenetic and morphogenetic effects of molecular oxygen and its derived reactive species in development

Authors: Hitchler, Michael J., Domann, Frederick E.

Source: In Free Radical Biology and Medicine July 2021 170:70-84

Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface

Authors: Wert, Katherine J., Velez, Gabriel, Cross, Madeline R., Wagner, Brett A., Teoh-Fitzgerald, Melissa L., Buettner, Garry R., McAnany, J. Jason, Olivier, Alicia, Tsang, Stephen H., Harper, Matthew M., Domann, Frederick E., Bassuk, Alexander G., Mahajan, Vinit B.

Source: In Free Radical Biology and Medicine 20 August 2018 124:408-419

Human Glioblastoma U87MG Cells Transduced with a Dominant Negative p53 (TP53) Adenovirus Construct Undergo Radiation-Induced Mitotic Catastrophe

Authors: Domann, Frederick E., Mackey, Michael A.

Source: Radiation Research, 2007 Aug 01. 168(2), 183-192.

Access URL: https://www.jstor.org/stable/4540716

Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research

Authors: Place, Trenton L., Domann, Frederick E., Case, Adam J.

Source: In Free Radical Biology and Medicine December 2017 113:311-322

O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate

Authors: Schoenfeld, Joshua D., Sibenaller, Zita A., Mapuskar, Kranti A., Wagner, Brett A., Cramer-Morales, Kimberly L., Furqan, Muhammad, Sandhu, Sonia, Carlisle, Thomas L., Smith, Mark C., Abu Hejleh, Taher, Berg, Daniel J., Zhang, Jun, Keech, John, Parekh, Kalpaj R., Bhatia, Sudershan, Monga, Varun, Bodeker, Kellie L., Ahmann, Logan, Vollstedt, Sandy, Brown, Heather, Shanahan Kauffman, Erin P., Schall, Mary E., Hohl, Ray J., Clamon, Gerald H., Greenlee, Jeremy D., Howard, Matthew A., Schultz, Michael K., Smith, Brian J., Riley, Dennis P., Domann, Frederick E., Cullen, Joseph J., Buettner, Garry R., Buatti, John M., Spitz, Douglas R., Allen, Bryan G.

Source: In Cancer Cell 10 April 2017 31(4):487-500

SOD2 targeted gene editing by CRISPR/Cas9 yields Human cells devoid of MnSOD

Authors: Cramer-Morales, Kimberly, Heer, Collin D., Mapuskar, Kranti A., Domann, Frederick E.

Source: In Free Radical Biology and Medicine December 2015 89:379-386

Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor β-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells

Authors: Hrabe, Jennifer E., O’Leary, Brianne R., Fath, Melissa A., Rodman, Samuel N., Button, Anna M., Domann, Frederick E., Spitz, Douglas R., Mezhir, James J.

Source: In Redox Biology August 2015 5:319-327

PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells

Authors: Vorrink, Sabine U., Sarsour, Ehab H., Olivier, Alicia K., Robertson, Larry W., Goswami, Prabhat C., Domann, Frederick E.

Source: In Experimental and Toxicologic Pathology October 2014 66(8):377-382

Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node

Authors: Vorrink, Sabine U., Domann, Frederick E.

Source: In Chemico-Biological Interactions 25 July 2014 218:82-88

Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines

Authors: Vorrink, Sabine U., Severson, Paul L., Kulak, Mikhail V., Futscher, Bernard W., Domann, Frederick E.

Source: In Toxicology and Applied Pharmacology 1 February 2014 274(3):408-416

Retroviral-infection increases tumorigenic potential of MDA-MB-231 breast carcinoma cells by expanding an aldehyde dehydrogenase (ALDH1) positive stem-cell like population

Authors: Wegman-Points, Lauren J., Teoh-Fitzgerald, Melissa L.T., Mao, Gaowei, Zhu, Yueming, Fath, Melissa A., Spitz, Douglas R., Domann, Frederick E.

Source: In Redox Biology 2014 2:847-854

Absence of manganese superoxide dismutase delays p53-induced tumor formation

Authors: Case, Adam J., Domann, Frederick E.

Source: In Redox Biology 2014 2:220-223

NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells

Authors: Sobhakumari, Arya, Schickling, Brandon M., Love-Homan, Laurie, Raeburn, Ayanna, Fletcher, Elise V.M., Case, Adam J., Domann, Frederick E., Miller, Francis J., Jr., Simons, Andrean L.

Source: In Toxicology and Applied Pharmacology 1 November 2013 272(3):736-745

Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursorcells

Authors: Case, Adam J., Madsen, Joshua M., Motto, David G., Meyerholz, David K., Domann, Frederick E.

Source: In Free Radical Biology and Medicine March 2013 56:17-27

Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes

Authors: Cyr, Anthony R., Brown, Kyle E., McCormick, Michael L., Coleman, Mitchell C., Case, Adam J., Watts, George S., Futscher, Bernard W., Spitz, Douglas R., Domann, Frederick E.

Source: In Redox Biology 2013 1(1):172-177

Differential activation of catalase expression and activity by PPAR agonists: Implications for astrocyte protection in anti-glioma therapy

Authors: Khoo, Nicholas K.H., Hebbar, Sachin, Zhao, Weiling, Moore, Steven A., Domann, Frederick E., Robbins, Mike E.

Source: In Redox Biology 2013 1(1):70-79

Low-Dose Radiation-Induced Enhancement of Thymic Lymphomagenesis in Lck-Bax Mice is Dependent on LET and Gender

Authors: Jacobus, James A., Duda, Chester G., Coleman, Mitchell C., Martin, Sean M., Mapuskar, Kranti, Mao, Gaowei, Smith, Brian J., Aykin-Burns, Nukhet, Guida, Peter, Gius, David, Domann, Frederick E., Knudson, C. Michael, Spitz, Douglas R.

Source: Radiation Research, 2013 Aug 01. 180(2), 156-165.

Access URL: http://dx.doi.org/10.1667/RR3293.1

Pharmacologic Ascorbate and DNMT Inhibitors Increase DUOX Expression and Peroxide-Mediated Toxicity in Pancreatic Cancer.

Authors: Steers, Garett J., O'Leary, Brianne R., Du, Juan, Wagner, Brett A., Carroll, Rory S., Domann, Frederick E., Goswami, Prabhat C., Buettner, Garry R., Cullen, Joseph J.

Source: Antioxidants; Sep2023, Vol. 12 Issue 9, p1683, 15p

Subject Terms: GENE expression, PANCREATIC cancer, DNA demethylation, DNA methyltransferases, METHYLCYTOSINE, VITAMIN C

Genomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2-• and H2O2

Authors: Owens, Kjerstin M., Aykin-Burns, Nūkhet, Dayal, Disha, Coleman, Mitchell C., Domann, Frederick E., Spitz, Douglas R.

Source: In Free Radical Biology and Medicine 1 January 2012 52(1):160-166