First-line pembrolizumab in patients with advanced non-small cell lung cancer and high PD-L1 expression: real-world data from a Spanish multicenter study

Authors: Aida Piedra, Sergio Martínez-Recio, Ainhoa Hernández, Teresa Morán, Edurne Arriola, Jordi Recuero-Borau, Manuel Cobo, Patricia Cordeiro, Joaquín Mosquera, Manuel Fernández, Rosario García-Campelo, Antonio Calles, Rosa Álvarez, María Zapata-García, Dolores Isla, Ana Callejo, Patricia Iranzo, Jorgina Serra-López, Andrés Barba, Ivana Sullivan, Enriqueta Felip, Margarita Majem

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: pembrolizumab, non-small cell lung cancer, first-line, predictive factors, high PD-L1 expression, immune check-point inhibitors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1510278/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/5bddfd2fdb244305bbfcb2496d8d7880

Sex differences in patients with Non-Small Cell Lung Cancer harboring driver fusions treated with tyrosine kinase inhibitors: a systematic review

Authors: Rita Leporati, Édouard Auclin, Daniel Morchón, Miquel Ferriol-Galmés, Juan Carlos Laguna, Teresa Gorria, Cristina Teixidó, Maria Aranzazu Amores, Paolo Ambrosini, Dolores Isla, Giuseppe Lo Russo, Laura Mezquita

Source: Therapeutic Advances in Medical Oncology, Vol 16 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/77f74f83c32c4cfaa6526f215542c0db

Association between missense variants of uncertain significance in the CHEK2 gene and hereditary breast cancer: a cosegregation and bioinformatics analysis

Authors: Natalia Alonso, Sebastián Menao, Rodrigo Lastra, María Arruebo, María P. Bueso, Esther Pérez, M. Laura Murillo, María Álvarez, Alba Alonso, Soraya Rebollar, Mara Cruellas, Dolores Arribas, Mónica Ramos, Dolores Isla, Juan José Galano-Frutos, Helena García-Cebollada, Javier Sancho, Raquel Andrés

Source: Frontiers in Genetics, Vol 14 (2024)

Subject Terms: cancer genetics, CHEK2, breast cancer, genetic testing, bioinformatics analysis, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2023.1274108/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/67daac7da8254e2b8514a30cfcc2a9ef

Cost-effectiveness of atezolizumab versus pembrolizumab as first-line treatment in PD-L1-positive advanced non-small-cell lung cancer in Spain

Authors: Dolores Isla, Marta Lopez-Brea, María Espinosa, Natalia Arrabal, Diego Pérez-Parente, David Carcedo, Reyes Bernabé-Caro

Source: Cost Effectiveness and Resource Allocation, Vol 21, Iss 1, Pp 1-11 (2023)

Subject Terms: Atezolizumab, Cost-effectiveness analysis, IMpower110 trial, Non-small cell lung cancer, PD-L1 expression, Pembrolizumab, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1478-7547

Access URL: https://doaj.org/article/2223e9f6ac504c0f90862782b22ec2dc

PD-1 is expressed in cytotoxic granules of NK cells and rapidly mobilized to the cell membrane following recognition of tumor cells

Authors: Cecilia Pesini, Sandra Hidalgo, Maykel A. Arias, Llipsy Santiago, Carlota Calvo, Maitane Ocariz-Díez, Dolores Isla, Pilar M. Lanuza, M José Agustín, Eva M Galvez, Ariel Ramírez-Labrada, Julián Pardo

Source: OncoImmunology, Vol 11, Iss 1 (2022)

Subject Terms: PD-1, natural killer cells, adoptive cell therapy, cell cytotoxicity, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/08ae5efbbd5a45038670c85d9e930634

LungBEAM: A prospective multicenter study to monitor stage IV NSCLC patients with EGFR mutations using BEAMing technology

Authors: Pilar Garrido, Luis Paz‐Ares, Margarita Majem, Teresa Morán, José Manuel Trigo, Joaquim Bosch‐Barrera, Rosario Garcίa‐Campelo, José Luis González‐Larriba, José Miguel Sánchez‐Torres, Dolores Isla, Núria Viñolas, Carlos Camps, Amelia Insa, Óscar Juan, Bartomeu Massuti, Alfredo Paredes, Ángel Artal, Marta López‐Brea, José Palacios, Enriqueta Felip

Source: Cancer Medicine, Vol 10, Iss 17, Pp 5878-5888 (2021)

Subject Terms: BEAMing, EGFR mutations, liquid biopsy, non‐small cell lung carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/2cc59ca7f06b4dfda7263238d2a0d956

Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain: OSIREX-Spanish Lung Cancer Group

Authors: Mariano Provencio, Josefa Terrasa, Pilar Garrido, Rosario García Campelo, Francisco Aparisi, Pilar Diz, David Aguiar, Carlos García-Giron, Julia Hidalgo, Carlos Aguado, Jorge García González, Emilio Esteban, Lorenzo Gómez-Aldavarí, Teresa Moran, Oscar Juan, Luís Enrique Chara, Juan L. Marti, Rafael López Castro, Ana Laura Ortega, Elia Martínez Moreno, Juan Coves, Ana M. Sánchez Peña, Joaquim Bosch-Barrera, Amparo Sánchez Gastaldo, Natalia Fernández Núñez, Edel del Barco, Manuel Cobo, Dolores Isla, Margarita Majem, Fátima Navarro, Virginia Calvo

Source: BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)

Subject Terms: Osimertinib, Real-world data, EGFR-activating mutations, T790M EGFR mutation, Second line, Non-small cell lung cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/8ebc0e8ffdc84091be87e3c5b709643d

Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung: Final analysis of the randomised phase 3 LUX-Lung 8 trial

Authors: Glenwood D. Goss, Manuel Cobo, Shun Lu, Konstantinos Syrigos, Ki Hyeong Lee, Erdem Göker, Vassilis Georgoulias, Dolores Isla, Alessandro Morabito, Young J. Min, Andrea Ardizzoni, Shaun Bender, Agnieszka Cseh, Enriqueta Felip

Source: EClinicalMedicine, Vol 37, Iss , Pp 100940- (2021)

Subject Terms: Afatinib, ERBB, Non-small cell lung cancer, Second-line, Squamous cell lung carcinoma, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537021002200; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/d8fe0d7fea454b01b8c9f6bcd8ec32f9

Diagnosis of Malnutrition According to GLIM Criteria Predicts Complications and 6-Month Survival in Cancer Outpatients

Authors: Marta Gascón-Ruiz, Diego Casas-Deza, Maria Marti-Pi, Irene Torres-Ramón, María Zapata-García, Andrea Sesma, Julio Lambea, María Álvarez-Alejandro, Elisa Quilez, Dolores Isla, Jose Miguel Arbonés-Mainar

Source: Biomedicines, Vol 10, Iss 9, p 2201 (2022)

Subject Terms: cancer, survival, GLIM, malnutrition, pain, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/9/2201; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/8ddec1fa644c40ffba979418f58fd5a6

Microbiota and Lung Cancer. Opportunities and Challenges for Improving Immunotherapy Efficacy

Authors: Maitane Ocáriz-Díez, Mara Cruellas, Marta Gascón, Rodrigo Lastra, Luis Martínez-Lostao, Ariel Ramírez-Labrada, José Ramón Paño, Andrea Sesma, Irene Torres, Alfonso Yubero, Julián Pardo, Dolores Isla, Eva M. Gálvez

Source: Frontiers in Oncology, Vol 10 (2020)

Subject Terms: microbiota, lung cancer, immunotherapy, lung microbiota, antibiotics, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2020.568939/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/3d61d072998e42e181eabeaf87b0c7ff

Clinical management and outcome of patients with advanced NSCLC carrying EGFR mutations in Spain

Authors: Edurne Arriola, Ramón García Gómez, Pilar Diz, Margarita Majem, Maite Martínez Aguillo, Javier Valdivia, Alfredo Paredes, José Miguel Sánchez-Torres, Sergio Peralta Muñoz, Isidoro Barneto, Vanesa Gutierrez, Jesús Manuel Andrade Santiago, Francisco Aparisi, Dolores Isla, Santiago Ponce, David Vicente Baz, Angel Artal, Mariluz Amador, Mariano Provencio

Source: BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)

Subject Terms: Clinical management, Chemotherapy, Epidermal growth factor receptor (EGFR) gene mutation, EGFR tyrosine kinase inhibitors (TKIs), Non-small-cell lung cancer (NSCLC), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-018-4004-7; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/5d99fbd38d4248848d0a056c93027a23

Intratumoral versus Circulating Lymphoid Cells as Predictive Biomarkers in Lung Cancer Patients Treated with Immune Checkpoint Inhibitors: Is the Easiest Path the Best One?

Authors: Marta Gascón, Dolores Isla, Mara Cruellas, Eva M. Gálvez, Rodrigo Lastra, Maitane Ocáriz, José Ramón Paño, Ariel Ramírez, Andrea Sesma, Irene Torres-Ramón, Alfonso Yubero, Julián Pardo, Luis Martínez-Lostao

Source: Cells, Vol 9, Iss 6, p 1525 (2020)

Subject Terms: biomarkers, lung cancer, immune cells in cancer, tumor microenvironment, immune checkpoints inhibitors, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/6/1525; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/c185481f819c47e49b8a770ab89cbf7a

Presentacion

Authors: Pilar Garrido, Dolores Isla

Source: Arbor: Ciencia, Pensamiento y Cultura, Vol 191, Iss 773, Pp a230-a230 (2015)

Subject Terms: General Works

File Description: electronic resource

Relation: http://arbor.revistas.csic.es/index.php/arbor/article/view/2033; https://doaj.org/toc/0210-1963; https://doaj.org/toc/1988-303X

Access URL: https://doaj.org/article/c10e909d82f546e2952ec1e53b510bf5

Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression.

Authors: Rafael Rosell, Laia Perez-Roca, Jose Javier Sanchez, Manuel Cobo, Teresa Moran, Imane Chaib, Mariano Provencio, Manuel Domine, Maria Angeles Sala, Ulpiano Jimenez, Pilar Diz, Isidoro Barneto, Jose Antonio Macias, Ramon de Las Peñas, Silvia Catot, Dolores Isla, Jose Miguel Sanchez, Rafael Ibeas, Guillermo Lopez-Vivanco, Juana Oramas, Pedro Mendez, Noemi Reguart, Remei Blanco, Miquel Taron

Source: PLoS ONE, Vol 4, Iss 5, p e5133 (2009)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2673583?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/8df183c3cfa54251ba5c08c80b585cbf

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P1-222: Activity and feasibility of biweekly carboplatin (Cb) plus Gemcitabine (G) as first line treatment in small cell lung cancer (SCLC) with extensive disease (ED)

Authors: Marti-Ciriquian, Juan L., Gil, Mireia, Blasco, Ana, Casado, Dolores Isla, Maestu, Immaculada

Source: In Journal of Thoracic Oncology August 2007 2(8) Supplement:S826-S827

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Activity and feasibility of biweekly carboplatin (Cb) plus Gemcitabine (G) as first line treatment in small cell lung cancer (SCLC) with extensive disease (ED).

Authors: Marti-Ciriquian, Juan L., Gil, Mireia, Blasco, Ana, Casado, Dolores Isla, Maestu, Immaculada

Source: Journal of Thoracic Oncology; 2007 Supplement 4, Vol. 2, pS826-S827, 2p

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