Safety and immunogenicity of GamEvac-Combi, a heterologous rVSV- and rAd5-vectored Ebola vaccine: a randomized controlled multicenter clinical trial in the Republic of Guinea and Russia

Authors: Denis Y. Logunov, Inna V. Dolzhikova, Mamadou Y. Boiro, Anna V. Kovyrshina, Alina S. Dzharullaeva, Alina S. Erokhova, Daria M. Grousova, Amir I. Tukhvatulin, Fatima M. Izhaeva, Yana V. Simakova, Maria K. Ordzhonikidze, Nadezhda L. Lubenets, Olga V. Zubkova, Dmitrii V. Scheblyakov, Ilias B. Esmagambetov, Maksim M. Shmarov, Alexander S. Semikhin, Natalia M. Tukhvatulina, Dmitrii N. Shcherbinin, Irina L. Tutykhina, Georgiy S. Prokhorov, Alexander A. Khovaev, Tatiana N. Demidova, Nikolai A. Malishev, Liliya N. Merkulova, Olga L. Voronina, Irina T. Fedyakina, Lidiya B. Kisteneva, Lyudmila V. Kolobukhina, Dmitry V. Mishin, Aleksandr L. Elakov, Ekaterina I. Ermolova, Kirill G. Krasnoslobodtsev, Viktor F. Larichev, Irina S. Kruzhkova, Egor M. Burmistrov, Anna B. Sheremet, Elizaveta A. Tokarskaya, Alexander V. Gromov, Dmitrii A. Reshetnikov, Aleksandr I. Fisun, Bogdan N. Kotiv, Dmitrii V. Ovchinnikov, Evgenii V. Ivchenko, Konstantin V. Zhdanov, Sergei M. Zakharenko, Aleksandr N. Solovev, Andrei M. Ivanov, Vitalii S. Sukachev, Roman V. Gudkov, Oleg V. Maltsev, Ilnur A. Gabdrakhmanov, Anton V. Barsukov, Vladislav V. Vashchenkov, Nikolai I. Demianenko, Sergei B. Ignatev, Konstantin V. Asiamov, Nikolai N. Kirichenko, Andrei V. Liubimov, Igor I. Volkov, Evgenii V. Kriukov, Nikolai K. Bazarnov, Viktoriia A. Kolodiazhnaia, Elena V. Kolomoets, Svetlana I. Syromyatnikova, Dmitry E. Chifanov, Alexander F. Andrus, Dmitry A. Kutaev, Sergei V. Borisevich, Boris S. Naroditsky, Alexander L. Gintsburg

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: clinical trials, vector vaccine, EVD, Ebola vaccine, prime-boost, rVSV, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1487039/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/d04dcb038a7d48f1872aaa5d969881da

Immunogenicity and Protectivity of Sputnik V Vaccine in hACE2-Transgenic Mice against Homologous and Heterologous SARS-CoV-2 Lineages Including Far-Distanced Omicron BA.5

Authors: Inna V. Dolzhikova, Amir I. Tukhvatulin, Daria M. Grousova, Ilya D. Zorkov, Marina E. Komyakova, Anna A. Ilyukhina, Anna V. Kovyrshina, Artem Y. Shelkov, Andrey G. Botikov, Ekaterina G. Samokhvalova, Dmitrii A. Reshetnikov, Andrey E. Siniavin, Daria M. Savina, Dmitrii V. Shcheblyakov, Fatima M. Izhaeva, Alina S. Dzharullaeva, Alina S. Erokhova, Olga Popova, Tatiana A. Ozharovskaya, Denis I. Zrelkin, Polina P. Goldovskaya, Alexander S. Semikhin, Olga V. Zubkova, Andrey A. Nedorubov, Vladimir A. Gushchin, Boris S. Naroditsky, Denis Y. Logunov, Alexander L. Gintsburg

Source: Vaccines, Vol 12, Iss 10, p 1152 (2024)

Subject Terms: vector vaccine, cross-protection, COVID-19 vaccine, hACE2-transgenic mice, immunogenicity, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/10/1152; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/5ca4e161630e45b996f7587289d1a662