Obesity amplifies influenza virus-driven disease severity in male and female mice

Authors: Alarcon, Pablo C., Damen, Michelle S.M.A., Ulanowicz, Cassidy J., Sawada, Keisuke, Oates, Jarren R., Toth, Andrea, Wayland, Jennifer L., Chung, Hak, Stankiewicz, Traci E., Moreno-Fernandez, Maria E., Szabo, Sara, Zacharias, William J., Divanovic, Senad

Source: In Mucosal Immunology December 2023 16(6):843-858

The bidirectional immune crosstalk in metabolic dysfunction-associated steatotic liver disease

Authors: Sawada, Keisuke, Chung, Hak, Softic, Samir, Moreno-Fernandez, Maria E., Divanovic, Senad

Source: In Cell Metabolism 7 November 2023 35(11):1852-1871

Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD

Authors: Park, Se-Hyung, Helsley, Robert N., Fadhul, Taghreed, Willoughby, Jennifer L.S., Noetzli, Leila, Tu, Ho-Chou, Solheim, Marie H., Fujisaka, Shiho, Pan, Hui, Dreyfuss, Jonathan M., Bons, Joanna, Rose, Jacob, King, Christina D., Schilling, Birgit, Lusis, Aldons J., Pan, Calvin, Gupta, Manoj, Kulkarni, Rohit N., Fitzgerald, Kevin, Kern, Philip A., Divanovic, Senad, Kahn, C. Ronald, Softic, Samir

Source: In Metabolism August 2023 145

Obesity Uncovers the Presence of Inflammatory Lung Macrophage Subsets With an Adipose Tissue Transcriptomic Signature in Influenza Virus Infection.

Authors: Alarcon, Pablo C, Ulanowicz, Cassidy J, Damen, Michelle S M A, Eom, John, Sawada, Keisuke, Chung, Hak, Alahakoon, Tara, Oates, Jarren R, Wayland, Jennifer L, Stankiewicz, Traci E, Moreno-Fernandez, Maria E, Zacharias, William J, Salomonis, Nathan, Divanovic, Senad

Source: Journal of Infectious Diseases; 2/15/2025, Vol. 231 Issue 2, pe317-e327, 11p

Subject Terms: WHITE adipose tissue, VIRAL pneumonia, DISEASE risk factors, VIRUS diseases, ADIPOSE tissues

Adipocyte inflammation and pathogenesis of viral pneumonias: an overlooked contribution

Authors: Alarcon, Pablo C., Damen, Michelle S.M.A., Madan, Rajat, Deepe, George S., Jr, Spearman, Paul, Way, Sing Sing, Divanovic, Senad

Source: In Mucosal Immunology November 2021 14(6):1224-1234

PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease

Authors: Moreno-Fernandez, Maria E., Giles, Daniel A., Oates, Jarren R., Chan, Calvin C., Damen, Michelle S.M.A., Doll, Jessica R., Stankiewicz, Traci E., Chen, Xiaoting, Chetal, Kashish, Karns, Rebekah, Weirauch, Matthew T., Romick-Rosendale, Lindsey, Xanthakos, Stavra A., Sheridan, Rachel, Szabo, Sara, Shah, Amy S., Helmrath, Michael A., Inge, Thomas H., Deshmukh, Hitesh, Salomonis, Nathan, Divanovic, Senad

Source: In Cell Metabolism 1 June 2021 33(6):1187-1204

Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet-induced obese mice

Authors: Jose, Shinsmon, Mukherjee, Anindita, Horrigan, Olivia, Setchell, Kenneth D.R., Zhang, Wujuan, Moreno-Fernandez, Maria E., Andersen, Heidi, Sharma, Divya, Haslam, David B., Divanovic, Senad, Madan, Rajat

Source: In Mucosal Immunology March 2021 14(2):500-510

BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birth

Authors: Doll, Jessica R., Moreno-Fernandez, Maria E., Stankiewicz, Traci E., Wayland, Jennifer L., Wilburn, Adrienne, Weinhaus, Benjamin, Chougnet, Claire A., Giordano, Daniela, Cappelletti, Monica, Presicce, Pietro, Kallapur, Suhas G., Salomonis, Nathan, Tilburgs, Tamara, Divanovic, Senad

Source: Cell reports. 42(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195186115.0x000001&indx=1&recIds=ETOCvdc_100195186115.0x000001

586 PATIENT-DERIVED ORGANOIDS REVEAL IMPAIRED MITOCHONDRIAL BIOENERGETIC EFFICIENCY IN THE COLON EPITHELIA OF PEDIATRIC PATIENTS WITH ULCERATIVE COLITIS

Authors: Ojo, Babajide A., Fox, Sejal R., Moreno-Fernandez, Maria E., Divanovic, Senad, de Jesus Perez, Vinicio, Rosen, Michael J.

Source: Gastroenterology. 164(6):S-110-S-110

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194430732.0x000001&indx=1&recIds=ETOCvdc_100194430732.0x000001

Metallothionein 3 Controls the Phenotype and Metabolic Programming of Alternatively Activated Macrophages

Authors: Chowdhury, Debabrata, Alrefai, Hani, Landero Figueroa, Julio A., Candor, Kathleen, Porollo, Aleksey, Fecher, Roger, Divanovic, Senad, Deepe, George S., Jr., Subramanian Vignesh, Kavitha

Source: In Cell Reports 25 June 2019 27(13):3873-3886

Fructose and hepatic insulin resistance

Authors: Softic, Samir, Stanhope, Kimber L., Boucher, Jeremie, Divanovic, Senad, Lanaspa, Miguel A., Johnson, Richard J., Kahn, C. Ronald

Source: Critical reviews in clinical laboratory sciences. 57(5):308-322

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111086633.0x000001&indx=1&recIds=ETOCvdc_100111086633.0x000001

BAFF neutralization impairs the autoantibody-mediated clearance of dead adipocytes and aggravates obesity-induced insulin resistance.

Authors: Lempicki, Melissa D., Gray, Jake A., Abuna, Gabriel, Murata, Ramiro M., Divanovic, Senad, McNamara, Coleen A., Meher, Akshaya K.

Source: Frontiers in Immunology; 2024, p1-18, 18p

Subject Terms: IMMUNOGLOBULIN light chains, WHITE adipose tissue, INSULIN resistance, FAT cells, PHAGOCYTOSIS

Short‐term high‐fat diet feeding protects from the development of experimental allergic asthma in mice

Authors: Schröder, Torsten, Wiese, Anna V., Ender, Fanny, Quell, Katharina M., Vollbrandt, Tillman, Duhn, Jannis, Sünderhauf, Annika, Künstner, Axel, Moreno‐Fernandez, Maria E., Derer, Stefanie, Aherrahrou, Zouhair, Lewkowich, Ian, Divanovic, Senad, Sina, Christian, Köhl, Jörg, Laumonnier, Yves

Source: Clinical & experimental allergy. 49(9):1245-1257

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103346160.0x000001&indx=1&recIds=ETOCvdc_100103346160.0x000001

Inflammation and Immunity: From an Adipocyte's Perspective

Authors: Chan, Calvin C., Damen, Michelle S.M.A., Alarcon, Pablo C., Sanchez-Gurmaches, Joan, Divanovic, Senad

Source: Journal of interferon and cytokine research. 39(8):459-471

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100086024992.0x000001&indx=1&recIds=ETOCvdc_100086024992.0x000001

GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network

Authors: Namjou, Bahram, Lingren, Todd, Huang, Yongbo, Parameswaran, Sreeja, Cobb, Beth, Stanaway, Ian, Connolly, John, Mentch, Frank, Benoit, Barbara, Niu, Xinnan, Wei, Wei-Qi, Carroll, Robert, Pacheco, Jennifer, Harley, Isaac, Divanovic, Senad, Carrell, David, Larson, Eric, Carey, David, Verma, Shefali, Ritchie, Marylyn, Gharavi, Ali, Murphy, Shawn, Williams, Marc, Crosslin, David, Jarvik, Gail, Kullo, Iftikhar, Hakonarson, Hakon, Li, Rongling, Xanthakos, Stavra, Harley, John

Source: BMC medicine. 17(1):1-19

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189298457.0x000001&indx=1&recIds=ETOCvdc_100189298457.0x000001

Greasing the inflammatory pathogenesis of viral pneumonias in diabetes

Authors: Damen, Michelle S. M. A., Alarcon, Pablo C., Shah, Amy S., Divanovic, Senad

Source: Obesity reviews. 23(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100146770565.0x000001&indx=1&recIds=ETOCvdc_100146770565.0x000001

Presurgery health influences outcomes following vertical sleeve gastrectomy in adolescents.

Authors: Swertfeger, Debi, Kim, Ahlee, Sexmith, Hannah, Moreno‐Fernandez, Maria E., Davidson, W. Sean, Helmrath, Michael, Jenkins, Todd, Okura, Tsuyoshi, Geh, Esmond, Xanthakos, Stavra A., Szabo, Sara, Nakamura, Takahisa, Divanovic, Senad, Shah, Amy Sanghavi

Source: Obesity (19307381); Jun2024, Vol. 32 Issue 6, p1187-1197, 11p

Subject Terms: SLEEVE gastrectomy, WEIGHT loss, DEMOGRAPHIC characteristics, RACE, TEENAGERS

Not Chopped Liver—A Careful, Fate-Mapping Study of Macrophages in NASH

Authors: Moreno-Fernandez, Maria E., Miraldi, Emily R., Divanovic, Senad

Source: Cell metabolism. 32(3):328-330

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120073083.0x000001&indx=1&recIds=ETOCvdc_100120073083.0x000001

Nicotinamide adenine dinucleotide phosphate (reduced) oxidase 2 modulates inflammatory vigor during nonalcoholic fatty liver disease progression in mice

Authors: Mukherjee, Rajib, Moreno‐Fernandez, Maria E., Giles, Daniel A., Cappelletti, Monica, Stankiewicz, Traci E., Chan, Calvin C., Divanovic, Senad

Source: Hepatology research. 2(5):546-560

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083713127.0x000001&indx=1&recIds=ETOCvdc_100083713127.0x000001

Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology

Authors: Zhang, Cai, Seo, Joonbae, Murakami, Kazutoshi, Salem, Esam, Bernhard, Elise, Borra, Vishnupriya, Choi, Kwangmin, Yuan, Celvie, Chan, Calvin, Chen, Xiaoting, Huang, Taosheng, Weirauch, Matthew, Divanovic, Senad, Qi, Nathan, Thomas, Hala, Mercer, Carol, Siomi, Haruhiko, Nakamura, Takahisa

Source: Nature communications. 9(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181173409.0x000001&indx=1&recIds=ETOCvdc_100181173409.0x000001