Sunitinib for metastatic progressive phaeochromocytomas and paragangliomas: results from FIRSTMAPPP, an academic, multicentre, international, randomised, placebo-controlled, double-blind, phase 2 trial

Authors: DOCAO, Christine, Drui, Delphine, Borson Chazot, Francoise, Chabre, Olivier, Vezzosi, Delphine, Castinetti, Frederic, Bertherat, Jérôme, Libé, Rossella, Gimenez-Roqueplo, Anne Paule, Favier, Judith, Quinkler, Marcus, Strasburger, Christian, Zopf, Katrin, Reincke, Martin, Kroiss, Matthias, Remde, Hanna, Haaf, Michaela, Fuß, Carmina T, Dischinger, Ulrich, Eisenhofer, Graeme, Pamporaki, Christina, Van Berkel, Anouk, Baudin, Eric ^*, Goichot, Bernard, Berruti, Alfredo, Hadoux, Julien, Moalla, Salma, Laboureau, Sandrine, Nölting, Svenja, de la Fouchardière, Christelle, Kienitz, Tina, Deutschbein, Timo, Zovato, Stefania, Amar, Laurence, Haissaguerre, Magalie, Timmers, Henri, Niccoli, Patricia, Faggiano, Antongiulio, Angokai, Moussa, Lamartina, Livia, Luca, Florina, Cosentini, Deborah, Hahner, Stefanie, Beuschlein, Felix, Attard, Marie, Texier, Matthieu, Fassnacht, Martin

Source: In The Lancet 16-22 March 2024 403(10431):1061-1070

Association of preclinical blood glucose with hospitalization rate and in‐hospital mortality: A single‐center retrospective cohort study

Authors: Kloock, Simon ¹, Skudelny, Danilo ², Kranke, Peter ³, Güder, Gülmisal ², Weismann, Dirk ⁴, Fassnacht, Martin ¹, Ziegler, Christian G. ^{1, 5}, Dischinger, Ulrich ^{1, *}

Source: In JACEP Open February 2024 5(1)

Obesity and its comorbidities, current treatment options and future perspectives: Challenging bariatric surgery?

Authors: Kloock, Simon, Ziegler, Christian G., Dischinger, Ulrich

Source: In Pharmacology and Therapeutics November 2023 251

Effect of bariatric surgery on cardio-psycho-metabolic outcomes in severe obesity: A randomized controlled trial

Authors: Koschker, Ann-Cathrin, Warrings, Bodo, Morbach, Caroline, Seyfried, Florian, Jung, Pius, Dischinger, Ulrich, Edelmann, Frank, Herrmann, Martin J., Stier, Christine, Frantz, Stefan, Malzahn, Uwe, Störk, Stefan, Fassnacht, Martin

Source: In Metabolism October 2023 147

Simplified urinary steroid profiling by LC-MS as diagnostic tool for malignancy in adrenocortical tumors

Authors: Vogg, Nora, Müller, Tobias, Floren, Andreas, Dandekar, Thomas, Riester, Anna, Dischinger, Ulrich, Kurlbaum, Max, Kroiss, Matthias, Fassnacht, Martin

Source: In Clinica Chimica Acta 15 March 2023 543

Hypothalamic integrity is necessary for sustained weight loss after bariatric surgery: A prospective, cross-sectional study

Authors: Dischinger, Ulrich, Kötzner, Laura, Kovatcheva-Datchary, Petia, Kleinschmidt, Helena, Haas, Christina, Perez, Jose, Presek, Cornelius, Koschker, Ann-Cathrin, Miras, Alexander D., Hankir, Mohammed K., Vogel, Jörg, Germer, Christoph-Thomas, Fassnacht, Martin, Herrmann, Martin J., Seyfried, Florian

Source: In Metabolism January 2023 138

The mutational landscape of ARMC5 in Primary Bilateral Macronodular Adrenal Hyperplasia: an update.

Authors: Bouys, Lucas, Vaczlavik, Anna, Cavalcante, Isadora P., Violon, Florian, Jouinot, Anne, Berthon, Annabel, Vaduva, Patricia, Espiard, Stéphanie, Perlemoine, Karine, Kamenicky, Peter, Vantyghem, Marie-Christine, Tabarin, Antoine, Raverot, Gérald, Ronchi, Cristina L., Dischinger, Ulrich, Reincke, Martin, Fragoso, Maria C., Stratakis, Constantine A., Chansavang, Albain, Pasmant, Eric

Source: Orphanet Journal of Rare Diseases; 2/5/2025, Vol. 20 Issue 1, p1-21, 21p

Subject Terms: CUSHING'S syndrome, LIFE sciences, ADRENAL glands, GERMPLASM, GENETICS, TUMOR suppressor genes

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity.

Authors: Sequeira, Vasco, Theisen, Julia, Ermer, Katharina J., Oertel, Marie, Xu, Anton, Weissman, David, Ecker, Katharina, Dudek, Jan, Fassnacht, Martin, Nickel, Alexander, Kohlhaas, Michael, Maack, Christoph, Dischinger, Ulrich

Source: ESC Heart Failure; Apr2025, Vol. 12 Issue 2, p1386-1397, 12p

Plasma Steroid Profiling in Patients With Adrenal Incidentaloma

Authors: Berke, Kristina, Constantinescu, Georgiana, Masjkur, Jimmy, Kimpel, Otilia, Dischinger, Ulrich, Peitzsch, Mirko, Kwapiszewska, Aleksandra, Dobrowolski, Piotr, Nölting, Svenja, Reincke, Martin, Beuschlein, Felix, Bornstein, Stefan R, Prejbisz, Aleksander, Lenders, Jacques W M, Fassnacht, Martin, Eisenhofer, Graeme

Source: Journal of clinical endocrinology & metabolism. 107(3):e1181-e1192

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100146878261.0x000001&indx=1&recIds=ETOCvdc_100146878261.0x000001

Mild autonomous cortisol secretion leads to reduced volumetric BMD at lumbar spine in patients with primary aldosteronism.

Authors: Mansour, Nabeel, Bruedgam, Denise, Heinrich, Daniel, Dischinger, Ulrich, Reisch, Nicole, Völter, Friederike, Stüfchen, Isabel, Nowak, Elisabeth, Zopp, Stephanie, Vasileva, Victoriya, Öcal, Osman, Wildgruber, Moritz, Seidensticker, Max, Ricke, Jens, Bidlingmaier, Martin, Reincke, Martin, Ribeiro de Oliveira Longo Schweizer, Juínia

Source: Frontiers in Endocrinology; 2024, p1-10, 10p

Subject Terms: CONVOLUTIONAL neural networks, BONE health, BONE density, BONE remodeling, ALKALINE phosphatase

Steroid Profiles and Precursor-to-Product Ratios Are Altered in Pregnant Women with Preeclampsia.

Authors: Trummer, Olivia, Stern, Christina, Reintar, Sharmaine, Mayer-Pickel, Karoline, Cervar-Zivkovic, Mila, Dischinger, Ulrich, Kurlbaum, Max, Huppertz, Berthold, Fluhr, Herbert, Obermayer-Pietsch, Barbara

Source: International Journal of Molecular Sciences; Dec2024, Vol. 25 Issue 23, p12704, 18p

Subject Terms: PREGNANCY proteins, SEX hormones, GENE expression, PREGNANT women, ENZYME metabolism, PREECLAMPSIA

Simulating the Post-gastric Bypass Intestinal Microenvironment Uncovers a Barrier-Stabilizing Role for FXR

Authors: Hankir, Mohammed K., Langseder, Theresa, Bankoglu, Ezgi Eyluel, Ghoreishi, Yalda, Dischinger, Ulrich, Kurlbaum, Max, Kroiss, Matthias, Otto, Christoph, le Roux, Carel W., Arora, Tulika, Seyfried, Florian, Schlegel, Nicolas

Source: In iScience 18 December 2020 23(12)

Limited effects of early life manipulations on sex-specific gene expression and behavior in adulthood

Authors: Candemir, Esin, Post, Antonia, Dischinger, Ulrich Severin, Palme, Rupert, Slattery, David A., O’Leary, Aet, Reif, Andreas

Source: In Behavioural Brain Research 2 September 2019 369

Characteristics of Patients Lost to Follow-up after Bariatric Surgery.

Authors: Krietenstein, Laura, Koschker, Ann-Cathrin, Miras, Alexander Dimitri, Kollmann, Lars, Gruber, Maximilian, Dischinger, Ulrich, Haubitz, Imme, Fassnacht, Martin, Warrings, Bodo, Seyfried, Florian

Source: Nutrients; Aug2024, Vol. 16 Issue 16, p2710, 17p

Disruptive effects of plasticizers bisphenol A, F, and S on steroidogenesis of adrenocortical cells.

Authors: Pötzl, Benedikt, Kürzinger, Lydia, Kendl, Sabine, Stopper, Helga, Kurlbaum, Max, Fassnacht, Martin, Dischinger, Ulrich

Source: Frontiers in Endocrinology; 2024, p1-16, 16p

Subject Terms: BISPHENOL A, ENDOCRINE disruptors, ADRENAL cortex, PLASTICIZERS, BISPHENOLS, CELL culture

Screening for Primary Aldosteronism by Mass Spectrometry Versus Immunoassay Measurements of Aldosterone: A Prospective Within-Patient Study.

Authors: Fuld, Sybille, Constantinescu, Georgiana, Pamporaki, Christina, Peitzsch, Mirko, Schulze, Manuel, Jun Yang, Müller, Lisa, Prejbisz, Aleksander, Januszewicz, Andrzej, Remde, Hanna, Kürzinger, Lydia, Dischinger, Ulrich, Ernst, Matthias, Gruber, Sven, Reincke, Martin, Beuschlein, Felix, Lenders, Jacques W. M., Eisenhofer, Graeme

Source: Journal of Applied Laboratory Medicine; Jul2024, Vol. 9 Issue 4, p752-766, 15p

Subject Terms: MASS spectrometry, MASS measurement, NOSOLOGY, MEDICAL screening, IMMUNOASSAY

GLP-1 and PYY3-36 reduce high-fat food preference additively after Roux-en-Y gastric bypass in diet-induced obese rats

Authors: Dischinger, Ulrich, Corteville, Caroline, Otto, Christoph, Fassnacht, Martin, Seyfried, Florian, Hankir, Mohammed K.

Source: Surgery for obesity and related diseases. 15(9):1483-1492

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100088961273.0x000001&indx=1&recIds=ETOCvdc_100088961273.0x000001

Susceptibility of Melanoma Cells to Targeted Therapy Correlates with Protection by Blood Neutrophils.

Authors: Wendlinger, Simone, Wohlfarth, Jonas, Siedel, Claudia, Kreft, Sophia, Kilian, Teresa, Junker, Sarah, Schmid, Luisa, Sinnberg, Tobias, Dischinger, Ulrich, Heppt, Markus V., Wistuba-Hamprecht, Kilian, Meier, Friedegund, Erpenbeck, Luise, Neubert, Elsa, Goebeler, Matthias, Gesierich, Anja, Schrama, David, Kosnopfel, Corinna, Schilling, Bastian

Source: Cancers; May2024, Vol. 16 Issue 9, p1767, 28p

Subject Terms: MELANOMA prognosis, THERAPEUTIC use of antineoplastic agents, IN vitro studies, MELANOMA, SKIN tumors, DRUG resistance in cancer cells, RESEARCH funding, NEUTROPHILS, CELL physiology, APOPTOSIS, TREATMENT effectiveness, CELLULAR signal transduction, DESCRIPTIVE statistics, LONGITUDINAL method, CELL lines, GENE expression, CANCER patient psychology, COMPARATIVE studies, BIOMARKERS, PHENOTYPES

Effects of NPY-2 Receptor Antagonists, Semaglutide, PYY 3-36 , and Empagliflozin on Early MASLD in Diet-Induced Obese Rats.

Authors: Kloock, Simon, Haerting, Niklas, Herzog, Gloria, Oertel, Marie, Geiger, Niklas, Geier, Andreas, Sequeira, Vasco, Nickel, Alexander, Kohlhaas, Michael, Fassnacht, Martin, Dischinger, Ulrich

Source: Nutrients; Mar2024, Vol. 16 Issue 6, p904, 14p

Effect of mild cortisol cosecretion on body composition and metabolic parameters in patients with primary hyperaldosteronism.

Authors: Mansour, Nabeel, Bruedgam, Denise, Dischinger, Ulrich, Kürzinger, Lydia, Adolf, Christian, Walter, Roman, Öcal, Osman, Schmidt, Vanessa F., Rudolph, Jan, Ricke, Jens, Reisch, Nicole, Reincke, Martin, Wildgruber, Moritz, Heinrich, Daniel

Source: Clinical Endocrinology; Mar2024, Vol. 100 Issue 3, p212-220, 9p

Subject Terms: BODY composition, HYDROCORTISONE, HYPERALDOSTERONISM, BLOOD cholesterol, LUMBOSACRAL region