Fluorescence lifetime: Beating the IRF and interpulse window

Authors: Fazel, Mohamadreza, Vallmitjana, Alexander, Scipioni, Lorenzo, Gratton, Enrico, Digman, Michelle A., Pressé, Steve

Source: Biophysical journal. 122(4):672-683

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185291384.0x000001&indx=1&recIds=ETOCvdc_100185291384.0x000001

Microenvironmental stiffness induces metabolic reprogramming in glioblastoma

Authors: Sohrabi, Alireza, Lefebvre, Austin E.Y.T., Harrison, Mollie J., Condro, Michael C., Sanazzaro, Talia M., Safarians, Gevick, Solomon, Itay, Bastola, Soniya, Kordbacheh, Shadi, Toh, Nadia, Kornblum, Harley I., Digman, Michelle A., Seidlits, Stephanie K.

Source: In Cell Reports 31 October 2023 42(10)

Superoxide Release by Macrophages through NADPH Oxidase Activation Dominating Chemistry by Isoprene Secondary Organic Aerosols and Quinones to Cause Oxidative Damage on Membranes

Authors: Fang, Ting, Huang, Yu-Kai, Wei, Jinlai, Mena, Jessica E. Monterrosa, Lakey, Pascale S. J., Kleinman, Michael T., Digman, Michelle A., Shiraiwa, Manabu

Source: Environmental science & technology. 56(23):17029-17038

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630912809&indx=1&recIds=ETOCRN630912809

Fluorescence Lifetime Imaging Detects Long-Lifetime Signal Associated with Reduced Pyocyanin at the Surface of Pseudomonas aeruginosa Biofilms and in Cross-Feeding Conditions.

Authors: Gallagher, Tara, Leemans, Simon, Dvornikov, Alexander S., Perinbam, Kumar, Fong, Joshua, Kim, Christina, Kapcia, Joseph, Kagawa, Miki, Grosvirt-Dramen, Adam, Hochbaum, Allon I., Digman, Michelle A., Gratton, Enrico, Siryaporn, Albert, Whiteson, Katrine

Source: ACS Infectious Diseases; 3/14/2025, Vol. 11 Issue 3, p543-549, 7p

Interfacial and Nanoconfinement Effects Decrease the Excited-State Acidity of Polymer-Bound Photoacids

Authors: Sanborn, Christopher D., Chacko, Jenu Varghese, Digman, Michelle, Ardo, Shane

Source: In Chem 13 June 2019 5(6):1648-1670

Number and brightness analysis to study spatio-temporal distribution of the angiotensin II AT1 and the endothelin-1 ETA receptors: Influence of ligand binding

Authors: Planes, Nadir, Digman, Michelle A., Vanderheyden, Patrick P.M.L., Gratton, Enrico, Caballero-George, Catherina

Source: In BBA - General Subjects May 2019 1863(5):917-924

Effect of Pathogenic Mutations on the Formation of High-Order Dynamin 2 Assemblies in Living Cells

Authors: Hedde, Per Niklas, Zhu, Songning, Barylko, Barbara, Chiu, Chi-Li, Nelson, Luke T., Digman, Michelle A., Albanesi, Joseph P., James, Nicholas G., Jameson, David M.

Source: Biochemistry; November 2024, Vol. 63 Issue: 21 p2750-2758, 9p

Number and molecular brightness analysis reveals Htt25Q protein aggregation upon the uptake of Htt97Q aggregates

Authors: Sameni, Sara, Zhang, Run, Digman, Michelle A.

Source: Biochemical and biophysical research communications. 522(1):133-137

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100095817183.0x000001&indx=1&recIds=ETOCvdc_100095817183.0x000001

Visible/Near-Infrared Emitting, Garnet-Based Paramagnetic-Persistent Luminescent Nanocrystals for Two-Photon Bioimaging

Authors: Sengar, Prakhar, Flores, Dora-Luz, Chauhan, Kanchan, Can-Uc, Bonifacio, Juarez-Moreno, Karla, Contreras, Oscar E., Digman, Michelle A., Hirata, Gustavo A.

Source: Crystal growth & design. 20(9):5880-5889

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631968672&indx=1&recIds=ETOCRN631968672

Hydrogel crosslinking modulates macrophages, fibroblasts, and their communication, during wound healing.

Authors: Butenko, Sergei, Nagalla, Raji R., Guerrero-Juarez, Christian F., Palomba, Francesco, David, Li-Mor, Nguyen, Ronald Q., Gay, Denise, Almet, Axel A., Digman, Michelle A., Nie, Qing, Scumpia, Philip O., Plikus, Maksim V., Liu, Wendy F.

Source: Nature Communications; 8/9/2024, Vol. 15 Issue 1, p1-17, 17p

Subject Terms: STROMAL cells, CELL fusion, RNA sequencing, SKIN injuries, HYDROGELS, WOUND healing

Quantitative image mean squared displacement (iMSD) analysis of the dynamics of profilin 1 at the membrane of live cells

Authors: Davey, Rhonda J., Digman, Michelle A., Gratton, Enrico, Moens, Pierre D.J.

Source: In Methods 1 May 2018 140-141:119-125

Label‐Free Metabolic Classification of Single Cells in Droplets Using the Phasor Approach to Fluorescence Lifetime Imaging Microscopy

Authors: Ma, Ning, Kamalakshakurup, Gopakumar, Aghaamoo, Mohammad, Lee, Abraham P., Digman, Michelle A.

Source: Cytometry.Part A. 95(1):93-100

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084330207.0x000001&indx=1&recIds=ETOCvdc_100084330207.0x000001

Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer's Disease Neurons by Imposed External Cys/CySS Redox Shifts

Authors: Dong, Yue, Sameni, Sara, Digman, Michelle, Brewer, Gregory

Source: Scientific reports. 9(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185680344.0x000001&indx=1&recIds=ETOCvdc_100185680344.0x000001

Age- and AD-related redox state of NADH in subcellular compartments by fluorescence lifetime imaging microscopy

Authors: Dong, Yue, Digman, Michelle A., Brewer, Gregory J.

Source: GeroScience. 41(1):51-67

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132353943.0x000001&indx=1&recIds=ETOCvdc_100132353943.0x000001

Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth

Authors: Romero-López, Mónica, Trinh, Andrew L., Sobrino, Agua, Hatch, Michaela M.S., Keating, Mark T., Fimbres, Cristhian, Lewis, David E., Gershon, Paul D., Botvinick, Elliot L., Digman, Michelle, Lowengrub, John S., Hughes, Christopher C.W.

Source: In Biomaterials February 2017 116:118-129

Viral highway to nucleus exposed by image correlation analyses

Authors: Mäntylä, Elina, Chacko, Jenu, Aho, Vesa, Parrish, Colin, Shahin, Victor, Kann, Michael, Digman, Michelle, Gratton, Enrico, Vihinen-Ranta, Maija

Source: Scientific reports. 8(1):1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111621004.0x000001&indx=1&recIds=ETOCvdc_100111621004.0x000001

Alteration in Fluidity of Cell Plasma Membrane in Huntington Disease Revealed by Spectral Phasor Analysis

Authors: Sameni, Sara, Malacrida, Leonel, Tan, Zhiqun, Digman, Michelle

Source: Scientific reports. 8(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103862176.0x000001&indx=1&recIds=ETOCvdc_100103862176.0x000001

Absence of REV3L promotes p53-regulated cancer cell metabolism in cisplatin-treated lung carcinoma cells

Authors: Kong, Linghao, Murata, Michael M., Digman, Michelle A.

Source: Biochemical and biophysical research communications. 496(1):199-204

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100055155845.0x000001&indx=1&recIds=ETOCvdc_100055155845.0x000001

Development of an image Mean Square Displacement (iMSD)-based method as a novel approach to study the intracellular trafficking of nanoparticles

Authors: Digiacomo, Luca, Digman, Michelle A., Gratton, Enrico, Caracciolo, Giulio

Source: In Acta Biomaterialia 15 September 2016 42:189-198

Phasor method to fluorescence lifetime microscopy to discriminate metabolic state of cells in living tissue