Revisiting trypanosomatid nucleoside diphosphate kinases

Authors: Miranda, Mariana R, Sayé, Melisa, Reigada, Chantal, Galceran, Facundo, Rengifo, Marcos, Maciel, Belen J, Digirolamo, Fabio A, Pereira, Claudio A

Source: Memórias do Instituto Oswaldo Cruz. January 2021 116

Subject Terms: nucleoside diphosphate kinase, nucleotides, nucleotide metabolism, multifunctionality, drug target

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Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762021000100853

Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas’ disease

Authors: Galceran, Facundo, Digirolamo, Fabio A., Rengifo, Marcos, Reigada, Chantal, Saye, Melisa, Maciel, Belen J., Estecho, Ivana G., Errasti, Andrea E., Pereira, Claudio A., Miranda, Mariana R.

Source: In Biochemical Pharmacology October 2023 216

The potential of the antifungal nystatin to be repurposed to fight the protozoan Trypanosoma cruzi.

Authors: Maciel, Belén Jesús, Reigada, Chantal, Digirolamo, Fabio Augusto, Rengifo, Marcos, Pereira, Claudio Alejandro, Miranda, Mariana Reneé, Sayé, Melisa

Source: Frontiers in Microbiology; 2025, p1-9, 9p

Subject Terms: CHAGAS' disease, PLASMA instabilities, DRUG repositioning, LIFE cycles (Biology), TRYPANOSOMA cruzi

IgE antibodies against Trypanosoma cruzi arginine kinase in patients with chronic Chagas disease

Authors: Valera-Vera, Edward Augusto, Concepción, Juan Luis, Cáceres, Ana Judith, Acevedo, Gonzalo Raúl, Fernández, Marisa, Hernández, Yolanda, Digirolamo, Fabio Augusto, Duschak, Vilma Gladys, Soprano, Luciana Lía, Pereira, Claudio Alejandro, Miranda, Mariana Reneé, Gómez, Karina Andrea ^*

Source: In Molecular Immunology October 2021 138:68-75

Cytosolic Trypanosoma cruzi nucleoside diphosphate kinase generates large granules that depend on its quaternary structure

Authors: Pereira, Claudio A., Reigada, Chantal, Sayé, Melisa, Digirolamo, Fabio A., Miranda, Mariana R.

Source: In Experimental Parasitology July 2014 142:43-50

A novel stage-specific glycosomal nucleoside diphosphate kinase from Trypanosoma cruzi

Authors: Cámara, María de los Milagros, Bouvier, León, Reigada, Chantal, Digirolamo, Fabio A, Sayé, Melisa, Pereira, Claudio A

Source: Folia parasitologica | 2017 Volume:64 | Number:1

Availability: http://data.europeana.eu/aggregation/europeana/336/uuid_82eeb46b_2b8d_4b02_be16_a395b61fcc6d

Trypanocidal activity of the anthocyanidin delphinidin, a non-competitive inhibitor of arginine kinase.

Authors: Valera-Vera, Edward, Reigada, Chantal, Sayé, Melisa, Digirolamo, Fabio A., Galceran, Facundo, Miranda, Mariana R., Pereira, Claudio A.

Source: Natural Product Research; Jun2022, Vol. 36 Issue 12, p3153-3157, 5p

Subject Terms: MOLECULAR dynamics, CHAGAS' disease, KINASE inhibitors, ANTHOCYANIDINS, TRYPANOSOMA cruzi, ANTIPARASITIC agents

Effect of capsaicin on the protozoan parasite Trypanosoma cruzi.

Authors: Valera-Vera, Edward A, Reigada, Chantal, Sayé, Melisa, Digirolamo, Fabio A, Galceran, Facundo, Miranda, Mariana R, Pereira, Claudio A

Source: FEMS Microbiology Letters; 12/1/2020, Vol. 367 Issue 23, p1-6, 6p

Subject Terms: TRYPANOSOMA cruzi, CAPSAICIN, CHAGAS' disease, PROTOZOA, DRUG development, CYANIDIN

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LA VÍA DE TRANSDUCCIÓN DE SEÑALES TOR DE MAMÍFEROS ESTÁ PRESENTE EN TRYPANOSOMA CRUZI. RECONSTRUCCIÓN IN SILICO Y POSIBLES FUNCIONES.

Alternate Title: The mammalian TOR pathway is present in Trypanosoma cruzi. In silico reconstruction and possible functions.

Authors: Digirolamo, Fabio A.¹, Miranda, Mariana R.¹, Bouvier, León A.¹, Cámara, María M.¹, Cánepa, Gaspar E.¹, Pereira, Claudio A.¹ cpereira@retina.ar

Source: Medicina (Buenos Aires). Jun2012, Vol. 72 Issue 3, p221-226. 6p. 2 Diagrams, 1 Chart.

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