Cryo-iCLEM: Cryo correlative light and electron microscopy with immersion objectives

Authors: Faul, Niko ^a, Chen, Shih-Ya ^a, Lamberz, Christian ^a, Bruckner, Mark ^a, Dienemann, Christian ^{b, ⁎}, Burg, Thomas P. ^{a, c, ⁎}

Source: In Journal of Structural Biology March 2025 217(1)

Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT

Authors: Engeholm, Maik ^{1, 4, ∗}, Roske, Johann J. ^{1, 2}, Oberbeckmann, Elisa ¹, Dienemann, Christian ¹, Lidschreiber, Michael ¹, Cramer, Patrick ^{1, ∗∗}, Farnung, Lucas ^{1, 3, ∗∗∗}

Source: In Molecular Cell 19 September 2024 84(18):3423-3437

Three-step mechanism of promoter escape by RNA polymerase II

Authors: Zhan, Yumeng, Grabbe, Frauke, Oberbeckmann, Elisa, Dienemann, Christian, Cramer, Patrick

Source: In Molecular Cell 2 May 2024 84(9):1699-1710

Structural insights into human co-transcriptional capping

Authors: Garg, Gaurika, Dienemann, Christian, Farnung, Lucas, Schwarz, Juliane, Linden, Andreas, Urlaub, Henning, Cramer, Patrick

Source: In Molecular Cell 20 July 2023 83(14):2464-2477

Structural basis of transcription reduction by a promoter-proximal +1 nucleosome

Authors: Abril-Garrido, Julio, Dienemann, Christian, Grabbe, Frauke, Velychko, Taras, Lidschreiber, Michael, Wang, Haibo, Cramer, Patrick

Source: In Molecular Cell 1 June 2023 83(11):1798-1809

Structural basis of SARS-CoV-2 polymerase inhibition by nonnucleoside inhibitor HeE1-2Tyr.

Authors: Kabinger, Florian, Doze, Valerie, Schmitzová, Jana, Lidschreiber, Michael, Dienemann, Christian, Cramer, Patrick

Source: Proceedings of the National Academy of Sciences of the United States of America; 3/11/2025, Vol. 122 Issue 10, p1-10, 24p

Allosteric transcription stimulation by RNA polymerase II super elongation complex

Authors: Chen, Ying, Vos, Seychelle M., Dienemann, Christian, Ninov, Momchil, Urlaub, Henning, Cramer, Patrick

Source: In Molecular Cell 19 August 2021 81(16):3386-3399

Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening

Authors: Schilbach, Sandra, Aibara, Shintaro, Dienemann, Christian, Grabbe, Frauke, Cramer, Patrick

Source: In Cell 22 July 2021 184(15):4064-4072

Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes

Authors: Hillen, Hauke S., Bartuli, Julia, Grimm, Clemens, Dienemann, Christian, Bedenk, Kristina, Szalay, Aladar A., Fischer, Utz, Cramer, Patrick

Source: In Cell 12 December 2019 179(7):1525-1536

Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes

Authors: Grimm, Clemens, Hillen, Hauke S., Bedenk, Kristina, Bartuli, Julia, Neyer, Simon, Zhang, Qian, Hüttenhofer, Alexander, Erlacher, Matthias, Dienemann, Christian, Schlosser, Andreas, Urlaub, Henning, Böttcher, Bettina, Szalay, Aladar A., Cramer, Patrick, Fischer, Utz

Source: In Cell 12 December 2019 179(7):1537-1550

Promoter Distortion and Opening in the RNA Polymerase II Cleft

Authors: Dienemann, Christian, Schwalb, Björn, Schilbach, Sandra, Cramer, Patrick

Source: In Molecular Cell 3 January 2019 73(1):97-106

Structural basis of TFIIH activation for nucleotide excision repair

Authors: Kokic, Goran, Chernev, Aleksandar, Tegunov, Dimitry, Dienemann, Christian, Urlaub, Henning, Cramer, Patrick

Source: Nature communications. 10(1):1-9

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182784497.0x000001&indx=1&recIds=ETOCvdc_100182784497.0x000001

Cryo-EM structures of lipidic fibrils of amyloid-β (1-40).

Authors: Frieg, Benedikt, Han, Mookyoung, Giller, Karin, Dienemann, Christian, Riedel, Dietmar, Becker, Stefan, Andreas, Loren B., Griesinger, Christian, Schröder, Gunnar F.

Source: Nature Communications; 2/13/2024, Vol. 15 Issue 1, p1-11, 11p

Neutralization of SARS‐CoV‐2 by highly potent, hyperthermostable, and mutation‐tolerant nanobodies

Authors: Güttler, Thomas, Aksu, Metin, Dickmanns, Antje, Stegmann, Kim M., Gregor, Kathrin, Rees, Renate, Taxer, Waltraud, Rymarenko, Oleh, Schünemann, Jürgen, Dienemann, Christian, Gunkel, Philip, Mussil, Bianka, Krull, Jens, Teichmann, Ulrike, Groß, Uwe, Cordes, Volker C, Dobbelstein, Matthias, Görlich, Dirk

Source: EMBO journal. 40(19)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131044341.0x000001&indx=1&recIds=ETOCvdc_100131044341.0x000001

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Authors: Kokic, Goran, Hillen, Hauke S., Tegunov, Dimitry, Dienemann, Christian, Seitz, Florian, Schmitzova, Jana, Farnung, Lucas, Siewert, Aaron, Höbartner, Claudia, Cramer, Patrick

Source: Nature communications. 12(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191413564.0x000001&indx=1&recIds=ETOCvdc_100191413564.0x000001

Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1

Authors: Düring, Jonas, Wolter, Madita, Toplak, Julia J., Torres, Camilo, Dybkov, Olexandr, Fokkens, Thornton J., Bohnsack, Katherine E., Urlaub, Henning, Steinchen, Wieland, Dienemann, Christian, Lorenz, Sonja

Source: Nature Structural and Molecular Biology; February 2024, Vol. 31 Issue: 2 p364-377, 14p

Mutants of Metal Binding Site M1 in APP E2 Show Metal Specific Differences in Binding of Heparin but Not of sorLA

Authors: Dienemann, Christian, Coburger, Ina, Mehmedbasic, Arnela, Andersen, Olav M., Than, Manuel E.

Source: Biochemistry. 54(15):2490-2499

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN600616491&indx=1&recIds=ETOCRN600616491

Structure of the transcribing RNA polymerase II–Elongin complex

Authors: Chen, Ying, Kokic, Goran, Dienemann, Christian, Dybkov, Olexandr, Urlaub, Henning, Cramer, Patrick

Source: Nature Structural and Molecular Biology; December 2023, Vol. 30 Issue: 12 p1925-1935, 11p

Crystal Structure of the VapBC Toxin–Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly

Authors: Dienemann, Christian, Bøggild, Andreas, Winther, Kristoffer S., Gerdes, Kenn, Brodersen, Ditlev E.

Source: In Journal of Molecular Biology 16 December 2011 414(5):713-722

Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.

Authors: Schilbach, Sandra, Wang, Haibo, Dienemann, Christian, Cramer, Patrick

Source: Proceedings of the National Academy of Sciences of the United States of America; 4/11/2023, Vol. 120 Issue 15, p1-7, 19p

Subject Terms: RNA polymerase II, PEPTIDES, ATOMIC models, YEAST