The microbiota metabolite, phloroglucinol, confers long-term protection against inflammation

Authors: Janire Castelo, Sarai Araujo-Aris, Diego Barriales, Samuel Tanner Pasco, Iratxe Seoane, Ainize Peña-Cearra, Ainhoa Palacios, Carolina Simó, Virginia Garcia-Cañas, Muthita Khamwong, Itziar Martín-Ruiz, Monika Gonzalez-Lopez, Laura Barcena, José Ezequiel Martín Rodríguez, José Luís Lavín, Naiara Gutiez, Raquel Marcos, Estibaliz Atondo, Arantza Cobela, Laura Plaza-Vinuesa, Adrián Plata, Eneko Santos-Fernandez, Alberto Fernandez-Tejada, Mari Carmen Villarán, José Miguel Mancheño, Juana Maria Flores, Ana María Aransay, Aize Pellón, Blanca de las Rivas, Rosario Muñoz, Abelardo Margolles, Patricia Ruas-Madiedo, Maria Victoria Selma, Mercedes Gomez de Agüero, Leticia Abecia, Juan Anguita, Héctor Rodríguez

Source: Gut Microbes, Vol 16, Iss 1 (2024)

Subject Terms: Microbiota byproducts, phenolic derivatives, central trained immunity, inflammation, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/b34810a018fb4213be0c1f08a497b946

Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation

Authors: Ainize Peña-Cearra, Ainhoa Palacios, Aize Pellon, Janire Castelo, Samuel Tanner Pasco, Iratxe Seoane, Diego Barriales, Jose Ezequiel Martin, Miguel Ángel Pascual-Itoiz, Monika Gonzalez-Lopez, Itziar Martín-Ruiz, Nuria Macías-Cámara, Naiara Gutiez, Sarai Araujo-Aris, Ana Mª Aransay, Héctor Rodríguez, Juan Anguita, Leticia Abecia

Source: Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/339c800c9b734603af6bfc909ed8fb27

Mitochondrial dysfunction promotes microbial composition that negatively impacts on ulcerative colitis development and progression

Authors: Ainize Peña-Cearra, Deguang Song, Janire Castelo, Ainhoa Palacios, Jose Luis Lavín, Mikel Azkargorta, Felix Elortza, Miguel Fuertes, Miguel Angel Pascual-Itoiz, Diego Barriales, Itziar Martín-Ruiz, Asier Fullaondo, Ana M. Aransay, Hector Rodríguez, Noah W. Palm, Juan Anguita, Leticia Abecia

Source: npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-14 (2023)

Subject Terms: Microbial ecology, QR100-130

File Description: electronic resource

Relation: https://doaj.org/toc/2055-5008

Access URL: https://doaj.org/article/3dff9ee3e3a641b592f1a6aa0abdf433

Mitochondrial dysfunction-associated microbiota establishes a transmissible refractory response to anti-TNF therapy during ulcerative colitis

Authors: Ainize Peña-Cearra, Janire Castelo, Jose Luis Lavín, Monika Gonzalez-Lopez, Miguel Angel Pascual-Itoiz, Miguel Fuertes, Virginia Gutiérrez de Juan, Laura Bárcena, Itziar Martín-Ruiz, Aize Pellón, Iratxe Seoane, Diego Barriales, Ainhoa Palacios, Asier Fullaondo, Iago Rodríguez-Lago, María L. Martinez-Chantar, Ana Mª Aransay, Hector Rodriguez, Juan Anguita, Leticia Abecia

Source: Gut Microbes, Vol 15, Iss 2 (2023)

Subject Terms: IBD, microbiota, complex I, mitochondriopathy, FcγR signaling, anti-TNF therapy, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/a753bfcd4ae14ccb8c85e30af3536b86

Mitochondrial complex I dysfunction alters the balance of soluble and membrane-bound TNF during chronic experimental colitis

Authors: Ainize Peña-Cearra, Miguel Angel Pascual-Itoiz, Jose Luis Lavín, Miguel Fuertes, Itziar Martín-Ruiz, Janire Castelo, Ainhoa Palacios, Diego Barriales, Asier Fullaondo, Ana M Aransay, Hector Rodríguez, Juan Anguita, Leticia Abecia

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/95933cae14fc4f7cbba28c2b763507b1

A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance

Authors: José Miguel Mancheño, Estíbaliz Atondo, Julen Tomás‐Cortázar, José Luís Lavín, Laura Plaza‐Vinuesa, Itziar Martín‐Ruiz, Diego Barriales, Ainhoa Palacios, Claudio Daniel Navo, Leticia Sampedro, Ainize Peña‐Cearra, Miguel Ángel Pascual‐Itoiz, Janire Castelo, Ana Carreras‐González, Donatello Castellana, Aize Pellón, Susana Delgado, Patricia Ruas‐Madiedo, Blanca delas Rivas, Leticia Abecia, Rosario Muñoz, Gonzalo Jiménez‐Osés, Juan Anguita, Héctor Rodríguez

Source: Microbial Biotechnology, Vol 15, Iss 2, Pp 648-667 (2022)

Subject Terms: Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://doaj.org/toc/1751-7915

Access URL: https://doaj.org/article/42fa39c9cb4949359c0dc9df09ee745e

Probing an Ixodes ricinus salivary gland yeast surface display with tick-exposed human sera to identify novel candidates for an anti-tick vaccine

Authors: Jos J. A. Trentelman, Julen Tomás-Cortázar, Sarah Knorr, Diego Barriales, Ondrej Hajdusek, Radek Sima, Jasmin I. Ersoz, Sukanya Narasimhan, Erol Fikrig, Ard M. Nijhof, Juan Anguita, Joppe W. Hovius

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/aecc1fe1ce21426d9843e8b3495ae2c8

A Catalogus Immune Muris of the mouse immune responses to diverse pathogens

Authors: Céline Barlier, Diego Barriales, Alexey Samosyuk, Sascha Jung, Srikanth Ravichandran, Yulia A. Medvedeva, Juan Anguita, Antonio del Sol

Source: Cell Death and Disease, Vol 12, Iss 9, Pp 1-9 (2021)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/c7f2cf9941e44be6a03cff557f5065c5

Oral vaccination stimulates neutrophil functionality and exerts protection in a Mycobacterium avium subsp. paratuberculosis infection model

Authors: Iraia Ladero-Auñon, Elena Molina, Maddi Oyanguren, Diego Barriales, Miguel Fuertes, Iker A. Sevilla, Lucy Luo, Rakel Arrazuria, Jeroen De Buck, Juan Anguita, Natalia Elguezabal

Source: npj Vaccines, Vol 6, Iss 1, Pp 1-15 (2021)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2059-0105

Access URL: https://doaj.org/article/0e308e07961c4a49aaad38bedf5df7ee

The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes

Authors: Aize Pellon, Diego Barriales, Ainize Peña-Cearra, Janire Castelo-Careaga, Ainhoa Palacios, Nerea Lopez, Estibaliz Atondo, Miguel Angel Pascual-Itoiz, Itziar Martín-Ruiz, Leticia Sampedro, Monika Gonzalez-Lopez, Laura Bárcena, Teresa Martín-Mateos, Jose María Landete, Rafael Prados-Rosales, Laura Plaza-Vinuesa, Rosario Muñoz, Blanca de las Rivas, Juan Miguel Rodríguez, Edurne Berra, Ana M. Aransay, Leticia Abecia, Jose Luis Lavín, Hector Rodríguez, Juan Anguita

Source: Gut Microbes, Vol 13, Iss 1 (2021)

Subject Terms: lactiplantibacillus plantarum, lactobacillus, monocytes, macrophages, innate immune memory, trained immunity, microbiota, immunometabolism, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/5cc2643c827d4d7d8582a2ff72e9b5bd

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart.

Authors: Diego Barriales, Itziar Martín-Ruiz, Ana Carreras-González, Marta Montesinos-Robledo, Mikel Azkargorta, Ibon Iloro, Iraide Escobés, Teresa Martín-Mateos, Estibaliz Atondo, Ainhoa Palacios, Monika Gonzalez-Lopez, Laura Bárcena, Ana R Cortázar, Diana Cabrera, Ainize Peña-Cearra, Sebastiaan M van Liempd, Juan M Falcón-Pérez, Miguel A Pascual-Itoiz, Juana María Flores, Leticia Abecia, Aize Pellon, Maria Luz Martínez-Chantar, Ana M Aransay, Alberto Pascual, Felix Elortza, Edurne Berra, José Luis Lavín, Héctor Rodríguez, Juan Anguita

Source: PLoS Biology, Vol 19, Iss 1, p e3001062 (2021)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/65e28a5181ec4bb4abc1d89b6cd6cf00

Identification of a highly active tannase enzyme from the oral pathogen Fusobacterium nucleatum subsp. polymorphum

Authors: Julen Tomás-Cortázar, Laura Plaza-Vinuesa, Blanca de las Rivas, José Luis Lavín, Diego Barriales, Leticia Abecia, José Miguel Mancheño, Ana M. Aransay, Rosario Muñoz, Juan Anguita, Héctor Rodríguez

Source: Microbial Cell Factories, Vol 17, Iss 1, Pp 1-10 (2018)

Subject Terms: Phenolics biotransformation, Tannase, Industrial, Fusobacterium, Oral pathogen, Microbiology, QR1-502

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12934-018-0880-4; https://doaj.org/toc/1475-2859

Access URL: https://doaj.org/article/afee518bd93e4bb29900470a39f9c9ce

Regulation of macrophage activity by surface receptors contained within Borrelia burgdorferi-enriched phagosomal fractions.

Authors: Ana Carreras-González, Diego Barriales, Ainhoa Palacios, Marta Montesinos-Robledo, Nicolás Navasa, Mikel Azkargorta, Ainize Peña-Cearra, Julen Tomás-Cortázar, Iraide Escobes, Miguel Angel Pascual-Itoiz, Jana Hradiská, Jan Kopecký, David Gil-Carton, Rafael Prados-Rosales, Leticia Abecia, Estíbaliz Atondo, Itziar Martín, Aize Pellón, Félix Elortza, Héctor Rodríguez, Juan Anguita

Source: PLoS Pathogens, Vol 15, Iss 11, p e1008163 (2019)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/d8deb873369c409392d9efe0a2b2952b

Identification and Characterization of Immunodominant Proteins from Tick Tissue Extracts Inducing a Protective Immune Response against Ixodes ricinus in Cattle

Authors: Sarah Knorr, Sophia Reissert-Oppermann, Julen Tomás-Cortázar, Diego Barriales, Mikel Azkargorta, Ibon Iloro, Félix Elortza, Sophia Pinecki-Socias, Juan Anguita, Joppe W. Hovius, Ard M. Nijhof

Source: Vaccines, Vol 9, Iss 6, p 636 (2021)

Subject Terms: Ixodes ricinus, immunoprecipitation, anti-tick vaccines, midgut, salivary glands, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/9/6/636; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/d815db52d1d14ce5bf1b737c1625efb5