Inducing hypertension in Myh11R247C/R247C mice triggers aortic dissections with increased focal adhesion kinase signaling

Authors: Callie S. Kwartler, Shanzhi Wang, Zhen Zhou, Pujun Guan, Yang Yu, Xue-Yan Duan, Theodore Zhang, Jiyuan Chen, Elaine C. Davis, Dianna M. Milewicz

Source: Frontiers in Cardiovascular Medicine, Vol 12 (2025)

Subject Terms: myosin heavy chain, focal adhesion, elastin-contractile unit, thoracic aortic dissection, vascular disease, aortic dissection, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2025.1492768/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/d13490a343ca4d2c8076a4e0dabd834c

Case studies in heritable vascular disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic Conference

Authors: Milan Jaiswal, BA, Lucas Ribe, MD, Rana O. Afifi, MD, Yuki Ikeno, MD, Alana C. Cecchi, MS, Bihong Zhao, MD, PhD, Akiko Tanaka, MD, PhD, Gustavo S. Oderich, MD, L. Maximilian Buja, MD, Dianna M. Milewicz, MD, PhD, Siddharth K. Prakash, MD, PhD, Anthony L. Estrera, MD

Source: Journal of Vascular Surgery Cases and Innovative Techniques, Vol 11, Iss 1, Pp 101684- (2025)

Subject Terms: Heritable thoracic aortic diseases, HTAD, TGFB2, Loeys-Dietz syndrome, LDS, Genetic testing, Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468428724002685; https://doaj.org/toc/2468-4287

Access URL: https://doaj.org/article/75b83d31542644e69dfd7e299121a31f

Mitral Annular Disjunction in Heritable Thoracic Aortic Disease: Insights From the Montalcino Aortic Consortium

Authors: Kishan L. Asokan, Jennifer R. Landes, Wannes Renders, Laura Muiño Mosquera, Julie De Backer, David W. Jantzen, Anji T. Yetman, Gisela Teixido‐Tura, Arturo Evangelista, Richmond Jeremy, Edward G. Jones, Shaine Morris, Tam Doan, Maral Ouzonian, Alan Braverman, Guillaume Jondeau, Olivier Milleron, Dianna M. Milewicz, Siddharth K. Prakash

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 21 (2024)

Subject Terms: cardiovascular genetics, congenital heart disease, Loeys–Dietz syndrome, mitral valve, thoracic aortic aneurysms and dissections, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/6412c93cdefe495f925a1a5d4ad6db2b

Insights From the Histopathologic Analysis of Acquired and Genetic Thoracic Aortic Aneurysms and Dissections

Authors: L. Maximilian Buja, MD, Bihong Zhao, MD, PhD, Humaira Sadaf, MD, Michelle McDonald, DO, Ana M. Segura, MD, Li Li, MD, PhD, Alana Cecchi, MS, Siddharth K. Prakash, MD, Rana O. Afifi, MD, Charles C. Miller, PhD, Anthony L. Estrera, MD, Dianna M. Milewicz, MD, PhD

Source: Texas Heart Institute Journal, Vol 51, Iss 1, Pp 1-13 (2024)

Subject Terms: aortic aneurysm, aortic dissection, tunica media, pathology, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1526-6702

Access URL: https://doaj.org/article/85a4cbd36f794ae5b7ad2b514235eca3

Resumen: Consenso internacional para la nomenclatura y clasificación de la válvula aórtica bicúspide congénita y su aortopatía, con fines clínicos, quirúrgicos, intervencionistas y de investigación

Authors: Hector I. Michelena, Alessandro della Corte, Arturo Evangelista, Joseph J. Maleszewski, William D. Edwards, Mary J. Roman, Richard B. Devereux, Borja Fernández, Federico M. Asch, Alex J. Barker, Lilia M. Sierra-Galán, Laurent de Kerchove, Susan M. Fernandes, Paul W.M. Fedak, Evaldas Girdauskas, Victoria Delgado, Suhny Abbara, Emmanuel Lansac, Siddharth K. Prakash, Malenka M. Bissell, Bogdan A. Popescu, Michael D. Hope, Marta Sitges, Vinod H. Thourani, Phillippe Pibarot, Krishnaswamy Chandrasekaran, Patrizio Lancellotti, Michael A. Borger, John K. Forrest, John Webb, Dianna M. Milewicz, Raj Makkar, Martin B. Leon, Stephen P. Sanders, Michael Markl, Victor A. Ferrari, William C. Roberts, Jae-Kwan Song, Philipp Blanke, Charles S. White, Samuel Siu, Lars G. Svensson, Alan C. Braverman, Joseph Bavaria, Thoralf M. Sundt, Gebrine El Khoury, Ruggero de Paulis, Maurice Enriquez-Sarano, Jeroen J. Bax, Catherine M. Otto, Hans-Joachim Schäfers

Source: Archivos de Cardiología de México, Vol 94, Iss 2 (2024)

Subject Terms: Válvula aórtica bicúspide. Aortopatía. Nomenclatura. Clasificación. VAB. Válvula aórtica bivalva., Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.archivoscardiologia.com/frame_esp.php?id=660; https://doaj.org/toc/1405-9940; https://doaj.org/toc/1665-1731

Access URL: https://doaj.org/article/125e7431c8484ba5a45f217644ca1d1c

Genome-First Approach to Rare and Common Variant Risk of Thoracic Aortic Aneurysm and Dissection

Authors: John Depaolo, Gina M. Biagetti, Renae Judy, Sarah Abramowitz, Nimesh Desai, Wilson Y. Szeto, Joseph E. Bavaria, Michael Levin, Dongchuan Guo, Dianna M. Milewicz, Scott M. Damrauer

Source: JVS - Vascular Science, Vol 5, Iss , Pp 100243- (2024)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666350324000543; https://doaj.org/toc/2666-3503

Access URL: https://doaj.org/article/98ed977f7fd14fe6adecd23a4848a50d

Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation

Authors: Suravi Majumder, Abhijnan Chattopadhyay, Jamie M. Wright, Pujun Guan, L. Maximilian Buja, Callie S. Kwartler, Dianna M. Milewicz

Source: JCI Insight, Vol 8, Iss 21 (2023)

Subject Terms: Genetics, Vascular biology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/360d3e60de4c43aebd762e0d1e32e849

Vertebral Tortuosity Is Associated With Increased Rate of Cardiovascular Events in Vascular Ehlers‐Danlos Syndrome

Authors: Sara B. Stephens, Sherene Shalhub, Nicholas Dodd, Jesse Li, Michael Huang, Seitaro Oda, Kalyan Kancherla, Tam T. Doan, Siddharth K. Prakash, Justin D. Weigand, Federico M. Asch, Taylor Beecroft, Alana Cecchi, Teniola Shittu, Liliana Preiss, Scott A. LeMaire, Richard B. Devereux, Reed E. Pyeritz, Kathryn W. Holmes, Mary J. Roman, Ronald V. Lacro, Ralph V. Shohet, Rajesh Krishnamurthy, Kim Eagle, Peter Byers, Dianna M. Milewicz, Shaine A. Morris

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 19 (2023)

Subject Terms: arterial rupture, cardiovascular, dissection, genetics, VEDS, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/baafb229fe084535a00ef7c97ecf8d3c

Proteomic analysis of descending thoracic aorta identifies unique and universal signatures of aneurysm and dissection

Authors: Louis Saddic, MD, PhD, Amanda Orosco, BS, Dongchuan Guo, PhD, Dianna M. Milewicz, MD, PhD, Dana Troxlair, MD, Richard Vander Heide, MD, David Herrington, MD, Yue Wang, PhD, Ali Azizzadeh, MD, Sarah J. Parker, PhD

Source: JVS - Vascular Science, Vol 3, Iss , Pp 85-181 (2022)

Subject Terms: Aneurysm, Descending thoracic aorta, Dissection, Proteomics, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666350322000013; https://doaj.org/toc/2666-3503

Access URL: https://doaj.org/article/23a0538677714a06ac21164fdd0831c7

Human SMAD4 Genomic Variants Identified in Individuals with Heritable and Early-Onset Thoracic Aortic Disease

Authors: Shreyas A. Bhave, Dongchuan Guo, Stoyan N. Angelov, Michael J. Bamshad, Deborah A. Nickerson, Dianna M. Milewicz, Mary C. Wallingford

Source: Cardiogenetics, Vol 11, Iss 3, Pp 132-138 (2021)

Subject Terms: genomic variants, hereditary hemorrhagic telangiectasia, thoracic aortic aneurysm, vascular malformations, SMAD4, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.mdpi.com/2035-8148/11/3/15; https://doaj.org/toc/2035-8253; https://doaj.org/toc/2035-8148

Access URL: https://doaj.org/article/ef8c115c55394e3996e080037497968e

Preventing Acute Aortic Dissections: The Power of Familial Screening and Risk Assessment

Authors: Alana C. Cecchi, Maura L. Boerio, Isabella Marin, Amélie Pinard, Dianna M. Milewicz

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 8 (2022)

Subject Terms: Editorials, familial thoracic aortic aneurysm and dissection, genetic screening, whole exome sequencing, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/90e555481b1c462daee0a12844492e6c

Patient-Specific Modeling Could Predict Occurrence of Pediatric Stroke

Authors: John D. Horn, Michael J. Johnson, Zbigniew Starosolski, Avner Meoded, Dianna M. Milewicz, Ananth Annapragada, Shaolie S. Hossain

Source: Frontiers in Physiology, Vol 13 (2022)

Subject Terms: moyamoya, MRI, wall shear rate score, computational fluid dynamics, stroke risk, cerebrovascular, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2022.846404/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/c898209b6867446389e42ceb87778dca

Identification of a common polymorphism in COQ8B acting as a modifier of thoracic aortic aneurysm severity

Authors: Benjamin J. Landis, Dongbing Lai, Dong-Chuan Guo, Joel S. Corvera, Muhammad T. Idrees, Henry W. Stadler, Christian Cuevas, Gavin U. Needler, Courtney E. Vujakovich, Dianna M. Milewicz, Robert B. Hinton, Stephanie M. Ware

Source: HGG Advances, Vol 3, Iss 1, Pp 100057- (2022)

Subject Terms: thoracic aortic aneurysm, aortic dissection, Marfan syndrome, bicuspid aortic valve, genetic modifier, coenzyme Q, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666247721000385; https://doaj.org/toc/2666-2477

Access URL: https://doaj.org/article/60059b4211c04ccaaf92dff1bc736065

Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog

Authors: Gerburg K. Schwaerzer, Hema Kalyanaraman, Darren E. Casteel, Nancy D. Dalton, Yusu Gu, Seunghoe Lee, Shunhui Zhuang, Nisreen Wahwah, Jan M. Schilling, Hemal H. Patel, Qian Zhang, Ayako Makino, Dianna M. Milewicz, Kirk L. Peterson, Gerry R. Boss, Renate B. Pilz

Source: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/1bb1d770c1fc4afd9a8c4a6eaa023c6b

Rare deleterious variants of NOTCH1, GATA4, SMAD6, and ROBO4 are enriched in BAV with early onset complications but not in BAV with heritable thoracic aortic disease

Authors: Fadi I. Musfee, Dongchuan Guo, Amélie C. Pinard, Ellen M. Hostetler, Elizabeth E. Blue, Deborah A. Nickerson, University of Washington Center for Mendelian Genomics (UW‐CMG), Michael J. Bamshad, Dianna M. Milewicz, Siddharth K. Prakash

Source: Molecular Genetics & Genomic Medicine, Vol 8, Iss 10, Pp n/a-n/a (2020)

Subject Terms: bicuspid aortic valve, thoracic aortic aneurysm, whole exome sequence, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2324-9269

Access URL: https://doaj.org/article/1d158b20e0ea44649fa7e87963d23e6a

Targeting the NLRP3 Inflammasome With Inhibitor MCC950 Prevents Aortic Aneurysms and Dissections in Mice

Authors: Pingping Ren, Darrell Wu, Richard Appel, Lin Zhang, Chen Zhang, Wei Luo, Avril A. B. Robertson, Matthew A. Cooper, Joseph S. Coselli, Dianna M. Milewicz, Ying H. Shen, Scott A. LeMaire

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 7 (2020)

Subject Terms: aortic destruction, MCC950, MMP‐9 activation, NLRP3 inflammasome inhibitor, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/9697ed46774843da83c108eadb75f75e

Familial aggregation of first degree relatives of children with essential hypertension

Authors: Monesha Gupta-Malhotra, Syed Shahrukh Hashmi, Michelle S. Barratt, Dianna M. Milewicz, Sanjay Shete

Source: Blood Pressure, Vol 27, Iss 5, Pp 289-296 (2018)

Subject Terms: primary hypertension, pediatrics, parental hypertension, sibling hypertension, genetics, risk factors, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/0803-7051; https://doaj.org/toc/1651-1999

Access URL: https://doaj.org/article/af131bf94fa349fb85cf62b37ae698b7

Fatal thoracic aortic aneurysm and dissection in a large family with a novel MYLK gene mutation: delineation of the clinical phenotype

Authors: Adel Shalata, Mohammad Mahroom, Dianna M. Milewicz, Gong Limin, Fadi Kassum, Khader Badarna, Nader Tarabeih, Nimmer Assy, Rona Fell, Hector Cohen, Munir Nashashibi, Alejandro Livoff, Muhammad Azab, George Habib, Dan Geiger, Omer Weissbrod, William Nseir

Source: Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-9 (2018)

Subject Terms: MYLK gene mutation, Aortic aneurysm and dissection, Genotype-phenotype, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13023-018-0769-7; https://doaj.org/toc/1750-1172

Access URL: https://doaj.org/article/7b6205a0ff824d4c92e62b8070c2af74

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

Authors: G. Todd Milne, on behalf of the Ironwood team, Peter Sandner, Kathleen A. Lincoln, Paul C. Harrison, Hongxing Chen, Hong Wang, Holly Clifford, Hu Sheng Qian, Diane Wong, Chris Sarko, Ryan Fryer, Jeremy Richman, Glenn A. Reinhart, Carine M. Boustany, Steven S. Pullen, Henriette Andresen, Lise Román Moltzau, Alessandro Cataliotti, Finn Olav Levy, Robert Lukowski, Sandra Frankenreiter, Andreas Friebe, Timothy Calamaras, Robert Baumgartner, Angela McLaughlin, Mark Aronovitz, Wendy Baur, Guang-Rong Wang, Navin Kapur, Richard Karas, Robert Blanton, Stefan Hell, Scott A. Waldman, Jieru E. Lin, Francheska Colon-Gonzalez, Gilbert W. Kim, Erik S. Blomain, Dante Merlino, Adam Snook, Jeanette Erdmann, Jana Wobst, Thorsten Kessler, Heribert Schunkert, Ulrich Walter, Oliver Pagel, Elena Walter, Stepan Gambaryan, Albert Smolenski, Kerstin Jurk, Rene Zahedi, James R. Klinger, Raymond L. Benza, Paul A. Corris, David Langleben, Robert Naeije, Gérald Simonneau, Christian Meier, Pablo Colorado, Mi Kyung Chang, Dennis Busse, Marius M. Hoeper, Jaime L. Masferrer, Sarah Jacobson, Guang Liu, Renee Sarno, Sylvie Bernier, Ping Zhang, Roger Flores-Costa, Mark Currie, Katherine Hall, Dorit Möhrle, Katrin Reimann, Steffen Wolter, Markus Wolters, Evanthia Mergia, Nicole Eichert, Hyun-Soon Geisler, Peter Ruth, Robert Feil, Ulrike Zimmermann, Doris Koesling, Marlies Knipper, Lukas Rüttiger, Yasutake Tanaka, Atsuko Okamoto, Takashi Nojiri, Motofumi Kumazoe, Takeshi Tokudome, Koichi Miura, Jun Hino, Hiroshi Hosoda, Mikiya Miyazato, Kenji Kangawa, Vikas Kapil, Amrita Ahluwalia, Nazareno Paolocci, Philip Eaton, James C. Campbell, Philipp Henning, Eugen Franz, Banumathi Sankaran, Friedrich W. Herberg, Choel Kim, M. Wittwer, Q. Luo, V. Kaila, S. A. Dames, Andrew Tobin, Mahmood Alam, Olena Rudyk, Susanne Krasemann, Kristin Hartmann, Oleksandra Prysyazhna, Min Zhang, Lan Zhao, Astrid Weiss, Ralph Schermuly, Amie J. Moyes, Sandy M. Chu, Reshma S. Baliga, Adrian J. Hobbs, Stylianos Michalakis, Regine Mühlfriedel, Christian Schön, Dominik M. Fischer, Barbara Wilhelm, Ditta Zobor, Susanne Kohl, Tobias Peters, Eberhart Zrenner, Karl Ulrich Bartz-Schmidt, Marius Ueffing, Bernd Wissinger, Mathias Seeliger, Martin Biel, RD-CURE consortium, Mark J. Ranek, Kristen M. Kokkonen, Dong I. Lee, Ronald J. Holewinski, Vineet Agrawal, Cornelia Virus, Donté A. Stevens, Masayuki Sasaki, Huaqun Zhang, Mathew M. Mannion, Peter P. Rainer, Richard C. Page, Jonathan C. Schisler, Jennifer E. Van Eyk, Monte S. Willis, David A. Kass, Manuela Zaccolo, Michael Russwurm, Jan Giesen, Corina Russwurm, Ernst-Martin Füchtbauer, Nadja I. Bork, Viacheslav O. Nikolaev, Luis Agulló, Martin Floor, Jordi Villà-Freixa, Ornella Manfra, Gaia Calamera, Nicoletta C. Surdo, Silja Meier, Alexander Froese, Kjetil Wessel Andressen, Annemarie Aue, Fabian Schwiering, Dieter Groneberg, Gzona Bajraktari, Jürgen Burhenne, Walter E. Haefeli, Johanna Weiss, Katharina Beck, Barbara Voussen, Alexander Vincent, Sean P. Parsons, Jan D. Huizinga, Fabiola Zakia Mónica, Edward Seto, Ferid Murad, Ka Bian, Joseph R. Burgoyne, Daniel Richards, Marianne Bjørnerem, Andrea Hembre Ulsund, Jeong Joo Kim, Sonia Donzelli, Mara Goetz, Kjestine Schmidt, Konstantina Stathopoulou, Jenna Scotcher, Christian Dees, Hariharan Subramanian, Elke Butt, Alisa Kamynina, S. Bruce King, Cor de Witt, Lars I. Leichert, Friederike Cuello, Hyazinth Dobrowinski, Moritz Lehners, Michael Paolillo Hannes Schmidt, Susanne Feil, Lai Wen, Martin Thunemann, Marcus Olbrich, Harald Langer, Meinrad Gawaz, Cor de Wit, Daniela Bertinetti, Hossein-Ardeschir Ghofrani, Friedrich Grimminger, Ekkehard Grünig, Yigao Huang, Pavel Jansa, Zhi Cheng Jing, David Kilpatrick, Stephan Rosenkranz, Flavia Menezes, Arno Fritsch, Sylvia Nikkho, Reiner Frey, Marc Humbert, Manuela Harloff, Joerg Reinders, Jens Schlossmann, Joon Jung, Jessica A. Wales, Cheng-Yu Chen, Linda Breci, Andrzej Weichsel, Sylvie G. Bernier, Robert Solinga, James E. Sheppeck, Paul A. Renhowe, William R. Montfort, Liying Qin, Ying-Ju Sung, Darren Casteel, Alexander Kollau, Andrea Neubauer, Astrid Schrammel, Bernd Mayer, Mika Takai, Chieri Takeuchi, Mai Kadomatsu, Shun Hiroi, Kanako Takamatsu, Hirofumi Tachibana, Marissa Opelt, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, John T. Fassett, Selene J. Sollie, Maria Hernandez-Valladares, Frode Berven, Kjetil W. Andressen, Miki Arai, Yutaka Suzuki, Meinoshin Okumura, Shinpei Kawaoka, Stefanie Peters, Hannes Schmidt, B. Selin Kenet, Sarah Helena Nies, Katharina Frank, Fritz G. Rathjen, Olga N. Petrova, Isabelle Lamarre, Michel Négrerie, Jerid W. Robinson, Jeremy R. Egbert, Julia Davydova, Laurinda A. Jaffe, Lincoln R. Potter, Nicholas Blixt, Leia C. Shuhaibar, Gordon L. Warren, Kim C. Mansky, Simone Romoli, Tobias Bauch, Karoline Dröbner, Frank Eitner, Mihály Ruppert, Tamás Radovits, Sevil Korkmaz-Icöz, Shiliang Li, Péter Hegedűs, Sivakanan Loganathan, Balázs Tamás Németh, Attila Oláh, Csaba Mátyás, Kálmán Benke, Béla Merkely, Matthias Karck, Gábor Szabó, Ulrike Scheib, Matthias Broser, Shatanik Mukherjee, Katja Stehfest, Christine E. Gee, Heinz G. Körschen, Thomas G. Oertner, Peter Hegemann, Deborah M. Dickey, Alexandre Dumoulin, Ralf Kühn, Laurinda Jaffe, Sophie Schobesberger, Peter Wright, Claire Poulet, Catherine Mansfield, Sian E. Harding, Julia Gorelik, Gerald Wölkart, Antonius C. F. Gorren, Gerburg K. Schwaerzer, Darren E. Casteel, Nancy D. Dalton, Yusu Gu, Shunhui Zhuang, Dianna M. Milewicz, Kirk L. Peterson, Renate Pilz, Aikaterini I. Argyriou, Garyfalia Makrynitsa, Ioannis I. Alexandropoulos, Andriana Stamopoulou, Marina Bantzi, Athanassios Giannis, Stavros Topouzis, Andreas Papapetropoulos, Georgios A. Spyroulias, Dennis J. Stuehr, Arnab Ghosh, Yue Dai, Saurav Misra, Boris Tchernychev, Inmaculada Silos-Santiago, Gerhard Hannig, Vu Thao-Vi Dao, Martin Deile, Pavel I. Nedvetsky, Andreas Güldner, César Ibarra-Alvarado, Axel Gödecke, Harald H. H. W. Schmidt, Angelos Vachaviolos, Andrea Gerling, Stefan Z. Lutz, Hans-Ulrich Häring, Marcel A. Krüger, Bernd J. Pichler, Michael J. Shipston, Sara Vandenwijngaert, Clara D. Ledsky, Obiajulu Agha, Dongjian Hu, Ibrahim J. Domian, Emmanuel S. Buys, Christopher Newton-Cheh, Donald B. Bloch, Nadine Mauro, Jonas Keppler, Wilson A. Ferreira, Hanan Chweih, Pamela L. Brito, Camila B. Almeida, Carla F. F. Penteado, Sara S. O. Saad, Fernando F. Costa, Paul S. Frenette, Damian Brockschnieder, Johannes-Peter Stasch, Nicola Conran, Daniel P. Zimmer, Jenny Tobin, Courtney Shea, Kimberly Long, Kim Tang, Peter Germano, James Wakefield, Ali Banijamali, G-Yoon Jamie Im, Albert T. Profy, Mark G. Currie

Source: BMC Pharmacology and Toxicology, Vol 18, Iss S1, Pp 1-35 (2017)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40360-017-0170-5; https://doaj.org/toc/2050-6511

Access URL: https://doaj.org/article/30c72e01121341e5b4f739303af28413

Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve

Authors: Bo Yang, Wei Zhou, Jiao Jiao, Jonas B. Nielsen, Michael R. Mathis, Mahyar Heydarpour, Guillaume Lettre, Lasse Folkersen, Siddharth Prakash, Claudia Schurmann, Lars Fritsche, Gregory A. Farnum, Maoxuan Lin, Mohammad Othman, Whitney Hornsby, Anisa Driscoll, Alexandra Levasseur, Marc Thomas, Linda Farhat, Marie-Pierre Dubé, Eric M. Isselbacher, Anders Franco-Cereceda, Dong-chuan Guo, Erwin P. Bottinger, G. Michael Deeb, Anna Booher, Sachin Kheterpal, Y. Eugene Chen, Hyun Min Kang, Jacob Kitzman, Heather J. Cordell, Bernard D. Keavney, Judith A. Goodship, Santhi K. Ganesh, Gonçalo Abecasis, Kim A. Eagle, Alan P. Boyle, Ruth J. F. Loos, Per Eriksson, Jean-Claude Tardif, Chad M. Brummett, Dianna M. Milewicz, Simon C. Body, Cristen J. Willer

Source: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/746483d8d43040b4bb874c6651724a72