A protein sequence-based deep transfer learning framework for identifying human proteome-wide deubiquitinase-substrate interactions

Authors: Yuan Liu, Dianke Li, Xin Zhang, Simin Xia, Yingjie Qu, Xinping Ling, Yang Li, Xiangren Kong, Lingqiang Zhang, Chun-Ping Cui, Dong Li

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c47a76b0a49f450ea1fcc1bfc36c2a15

Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing

Authors: Junjie Hu, Lele Zhang, Haoran Xia, Yilv Yan, Xinsheng Zhu, Fenghuan Sun, Liangdong Sun, Shuangyi Li, Dianke Li, Jin Wang, Ya Han, Jing Zhang, Dongliang Bian, Huansha Yu, Yan Chen, Pengyu Fan, Qiang Ma, Gening Jiang, Chenfei Wang, Peng Zhang

Source: Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)

Subject Terms: Immunotherapy, Tumor microenvironment, Non-small cell lung cancer, Single cell, Neutrophil, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/0a72fd6a99f54adfb378bdad5583c382

Comparative profiling of single-cell transcriptome reveals heterogeneity of tumor microenvironment between solid and acinar lung adenocarcinoma

Authors: Dianke Li, Huansha Yu, Junjie Hu, Shaoling Li, Yilv Yan, Shuangyi Li, Liangdong Sun, Gening Jiang, Likun Hou, Lele Zhang, Peng Zhang

Source: Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-21 (2022)

Subject Terms: Lung adenocarcinoma, Histology, Tumor immune microenvironment, Tumor metabolism, Immunotherapy, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/a0a51cdb093447b380946de27b58993d

Single‐Cell Transcriptome Identifies Drug‐Resistance Signature and Immunosuppressive Microenvironment in Metastatic Small Cell Lung Cancer

Authors: Jing Zhang, Haiping Zhang, Lele Zhang, Dianke Li, Mengfan Qi, Liping Zhang, Huansha Yu, Di Wang, Gening Jiang, Xujun Wang, Xianmin Zhu, Peng Zhang

Source: Advanced Genetics, Vol 3, Iss 2, Pp n/a-n/a (2022)

Subject Terms: heterogeneity, natural killer cells, single‐cell RNA sequencing, small cell lung cancer, tumor microenvironments, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2641-6573

Access URL: https://doaj.org/article/018ba83f36e0482b9a1b7a13f28c3a14

Integration of Human Protein Sequence and Protein-Protein Interaction Data by Graph Autoencoder to Identify Novel Protein-Abnormal Phenotype Associations

Authors: Yuan Liu, Ruirui He, Yingjie Qu, Yuan Zhu, Dianke Li, Xinping Ling, Simin Xia, Zhenqiu Li, Dong Li

Source: Cells, Vol 11, Iss 16, p 2485 (2022)

Subject Terms: deep learning, graph autoencoder, protein-phenotype associations prediction, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/16/2485; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/e5da7215c649434685468aafebc8c7b1