Multimodal Synergistic Strategies for Diabetic Wound Healing Using Glucose Oxidase Nanocomposites: Therapeutic Mechanisms and Nanomaterial Design

Authors: Fan Z, Liang C, Zhang J, Li Y, Tan L, Deng H, Wang P, Wang J, Kang J, Zhu Y, Fu H, Tao J

Source: International Journal of Nanomedicine, Vol Volume 20, Iss Issue 1, Pp 5727-5762 (2025)

Subject Terms: Glucose Oxidase, wound healing, Synergistic Strategies, Nanocomposite, Diabetic wounds, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/multimodal-synergistic-strategies-for-diabetic-wound-healing-using-glu-peer-reviewed-fulltext-article-IJN; https://doaj.org/toc/1178-2013

Access URL: https://doaj.org/article/17c1a4fc6ae34cd4b2ca14b7f33a43d9

FG-4592 combined with PRP significantly accelerates the healing of refractory diabetic wounds by upregulating HIF-1α

Authors: Di Tang, Qiang Lin, Pei-Wen Li, Song Wang, Kai Xu, Yue-Sheng Huang, Qi-Ping Lu

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-14 (2025)

Subject Terms: Diabetic wounds, FG-4592, Hypoxia-inducible factor-1, PRP, Vascular endothelial growth factor, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0d308f90673e4d55b07a12303d7d5f50

Dual-layer microneedles with NO/O2 releasing for diabetic wound healing via neurogenesis, angiogenesis, and immune modulation

Authors: Changjiang Liu, Kun Liu, Dong Zhang, Yuting Liu, Yifeng Yu, Haifei Kang, Xianzhen Dong, Honglian Dai, Aixi Yu

Source: Bioactive Materials, Vol 46, Iss , Pp 213-228 (2025)

Subject Terms: Microneedles, Gas delivery, Neurogenesis, Angiogenesis, Immune modulation, Diabetic wounds, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X24005486; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/6f7a04a570694729b7f12d4331fa3526

Inflammatory memory-activated biomimetic nanovesicles regulate neutrophil plasticity and metabolic reprogramming for rapid diabetic wound healing via targeting miR-193a-5p/TLR4/JNK/P38 MAPK pathways

Authors: Yunlong Fan, Jiaman Yang, Yulin Xie, Xin Yang, He Zhu, Yuanyuan Liu, Zhikuan Xia, Shuaifei Ji, Rongya Yang

Source: Journal of Nanobiotechnology, Vol 23, Iss 1, Pp 1-20 (2025)

Subject Terms: Inflammatory memory, Mimetic nanovesicles, Epidermal stem cells, Neutrophils, Diabetic wounds, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/97aa807c37dc4cc18471af93ee75b595

In vitro evaluation of silver-zinc oxide-eugenol nanocomposite for enhanced antimicrobial and wound healing applications in diabetic conditions

Authors: Hari Prasath Nagaiah, Malik Basha Samsudeen, Akshaya Rani Augustus, Karutha Pandian Shunmugiah

Source: Discover Nano, Vol 20, Iss 1, Pp 1-30 (2025)

Subject Terms: Antimicrobial resistance, Wound healing, Diabetic wounds, Chronic infections, Glucose uptake, Materials of engineering and construction. Mechanics of materials, TA401-492

File Description: electronic resource

Relation: https://doaj.org/toc/2731-9229

Access URL: https://doaj.org/article/48bf855b57b346b6b95e99e6e5881e8a

Beta-boswellic acid facilitates diabetic wound healing by targeting STAT3 and inhibiting ferroptosis in fibroblasts

Authors: Ziyang Han, Weiping Wu, Zeming Bai, Yiping Xiu, Dapeng Zhou

Source: Frontiers in Pharmacology, Vol 16 (2025)

Subject Terms: boswellic acid, STAT3, Ferroptosis, network analysis, diabetic wounds, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2025.1578625/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/c771a747f47140c989171a5c8abeb84d

An MXene nanocomposite hydrogel for enhanced diabetic infected wound healing via photothermal antibacterial properties and bioactive molecule integration

Authors: Xue Ou, Zhijie Yu, Xi Zheng, Le Chen, Chuanyu Pan, Dandan Li, Zhenzhen Qiao, Xiaoyuan Zheng

Source: Materials Today Bio, Vol 31, Iss , Pp 101538- (2025)

Subject Terms: Diabetic wounds, Ti₃C₂Tx-Ag, Nanocomposite hydrogel, Photothermal antibacterial, Wound healing, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590006425000961; https://doaj.org/toc/2590-0064

Access URL: https://doaj.org/article/ab51ff214fe94ad1b0d1a0df100f1961

Hybrid hydrogel based on porcine-derived matrix with gallic acid and cerium-doped mesoporous bioactive glass for diabetic wound healing

Authors: Hao Zeng, Qinghong Lai, Wuqiang Liao, Jiajin Tu, Junfeng Sun

Source: Materials & Design, Vol 251, Iss , Pp 113714- (2025)

Subject Terms: Diabetic wounds, Hydrogel dressings, Immunomodulation, Gallic acid, Bioactive glass nanoparticles, Materials of engineering and construction. Mechanics of materials, TA401-492

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0264127525001340; https://doaj.org/toc/0264-1275

Access URL: https://doaj.org/article/b22ab47ec007423fb7bb9309829546a2

The thirty-year research in growth factors for diabetic-wound care: Visual analysis and insights

Authors: Kexin Deng, Bo Zhou

Source: Asian Journal of Surgery, Vol 48, Iss 1, Pp 934-936 (2025)

Subject Terms: Bibliometric, Citespace, Diabetic wounds, Growth factors, Surgery, RD1-811

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S101595842401741X; https://doaj.org/toc/1015-9584

Access URL: https://doaj.org/article/1df4ed036de9493c91331a1633c6b0e5

Implications of pH and Ionic Environment in Chronic Diabetic Wounds: An Overlooked Perspective

Authors: Guo J, Cao Y, Wu QY, Zhou YM, Cao YH, Cen LS

Source: Clinical, Cosmetic and Investigational Dermatology, Vol Volume 17, Pp 2669-2686 (2024)

Subject Terms: chronic diabetic wounds, ph, ions, ionic environment, wound healing, review, Dermatology, RL1-803

File Description: electronic resource

Relation: https://www.dovepress.com/implications-of-ph-and-ionic-environment-in-chronic-diabetic-wounds-an-peer-reviewed-fulltext-article-CCID; https://doaj.org/toc/1178-7015

Access URL: https://doaj.org/article/a48e7a511f21490a859e0eb09d448211

Smart photonic crystal hydrogels for visual glucose monitoring in diabetic wound healing

Authors: Xuxia Yang, Langjie Chai, Zhuo Huang, Bo Zhu, Haiyang Liu, Zhantian Shi, You Wu, Liang Guo, Longjian Xue, Yifeng Lei

Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-15 (2024)

Subject Terms: Diabetic wounds, Glucose-responsive hydrogel, Visual monitoring, Photonic crystal, Structure colors, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/1267d4c7f0954871bd791822aa5d1050

Zinc-based Polyoxometalate Nanozyme Functionalized Hydrogels for optimizing the Hyperglycemic-Immune Microenvironment to Promote Diabetic Wound Regeneration

Authors: Chaoyu Pu, Yong Wang, Honglin Xiang, Jiangtao He, Qiyuan Sun, Yuan Yong, Lu Chen, Ke Jiang, Hanfeng Yang, Yuling Li

Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-27 (2024)

Subject Terms: Diabetic wounds, Hyperglycaemic microenvironment, Immune microenvironment, Nanozymes, Hydrogels, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/f8c5fa631aa745bfb73f102f4815033b

Desferrioxamine-Laden Nanofibrous Scaffolds with Efficient Angiogenesis for Accelerating Diabetic Wound Healing

Authors: Zhao Y, Chen J, Zhou M, Zhang G, Wu W, Wang Z, Sun J, Zhong A

Source: International Journal of Nanomedicine, Vol Volume 19, Pp 10551-10568 (2024)

Subject Terms: diabetic wounds, angiogenesis, desferrioxamine, graphene oxide, electrospinning, drug release., Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/desferrioxamine-laden-nanofibrous-scaffolds-with-efficient-angiogenesi-peer-reviewed-fulltext-article-IJN; https://doaj.org/toc/1178-2013

Access URL: https://doaj.org/article/dbefc4fd115144aaa6aaed3e16686189

A novel hydrogel loaded with plant exosomes and stem cell exosomes as a new strategy for treating diabetic wounds

Authors: Jialu Weng, Yizhang Chen, Yuhan Zeng, Wenzhang Jin, Ying Ji, Wa Zhang, Shunfu Wang, Haobing Li, Meilin Yi, Xiaoying Niu, Xuchen Deng, Jiancheng Huang, Xiang Su, Lulu Chen

Source: Materials Today Bio, Vol 32, Iss , Pp 101810- (2025)

Subject Terms: Momordica charantia, Mesenchymal stem cell, Exosomes, Hydrogel, Diabetic wounds, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590006425003709; https://doaj.org/toc/2590-0064

Access URL: https://doaj.org/article/8cf4576f404b487f811e036ad2341a4e

A highly transparent dopamine-copolymerized hydrogel with enhanced ROS-scavenging and tissue-adhesive properties for chronic diabetic wounds

Authors: Zhang, Haiqi ^a, Wang, Jinze ^a, Hu, Hongtao ^a, Ma, Lie ^{a, b, ⁎}

Source: In Acta Biomaterialia 15 May 2025 198:161-173

Application of sodium alginate and polyethylene glycol bilayer multifunctional hydrogel microneedles in infectious and diabetic wounds

Authors: Hou, Bao ^{a, 1}, Xu, Anjing ^{a, 1}, Zhang, Shijie ^{a, 1}, Cai, Weiwei ^{a, 1}, Wen, Yuanyuan ^a, Wang, Yao ^a, Zhu, Xuexue ^a, Huang, Shubing ^a, Huang, Jiarui ^a, Qiu, Liying ^{a, ⁎}, Sun, Haijian ^{a, b, ⁎⁎}

Source: In International Journal of Biological Macromolecules May 2025 310 Part 4

Review: Advances in multifunctional hydrogels based on carbohydrate polymer and protein in the treatment of diabetic wounds

Authors: Sun, Jishang ^a, Song, Leyang ^a, Zhou, Yi ^a, Wu, Keying ^a, Li, Cuiyao ^a, Han, Baoqin ^{a, b}, Chang, Jing ^{a, b, ⁎}

Source: In International Journal of Biological Macromolecules May 2025 309 Part 2

Physicochemical properties of bacterial cellulose/phototherapeutic polypyrrole/antibacterial chitosan composite membranes and their evaluation as chronic wound dressings

Authors: Don, Trong-Ming ^a, Lee, Kuan-Ting ^a, Chen, Bo-Yi ^a, Tang, Shuoheng ^b, Huang, Yi-Cheng ^{b, ⁎}, Chuang, Andrew E.-Y. ^{c, ⁎}

Source: In International Journal of Biological Macromolecules May 2025 308 Part 1

Structure characterization of a Bletilla striata homogeneous polysaccharide and its effects on reducing oxidative stress and promoting wound healing in diabetic rats

Authors: Li, Yuanlin ^{a, 1}, Hao, Yinxue ^{a, 1}, Yang, Xiaoqi ^a, Zhao, Jiahui ^a, Chang, Ruiying ^a, Wang, Bo ^{c, d, ⁎}, Zhan, Xueyan ^{a, b, ⁎⁎}

Source: In International Journal of Biological Macromolecules May 2025 307 Part 3

Integrated insights into gene expression dynamics and transcription factor roles in diabetic and diabetic-infectious wound healing using rat model

Authors: Sharma, Vikash ^{a, b}, Singh, Jitender ^{a, 1}, Kumar, Yash ^{a, 1}, Kumar, Ashish ^a, Venkatesan, Kumar ^c, Mukherjee, Monalisa ^{d, ⁎}, Sharma, Arun K. ^{a, ⁎⁎}

Source: In Life Sciences 1 May 2025 368