Non-coding RNAs affecting NLRP3 inflammasome pathway in diabetic cardiomyopathy: a comprehensive review of potential therapeutic options.

Authors: Radmehr, Elahe^1,2 (AUTHOR), Yazdanpanah, Niloufar^2,3,4 (AUTHOR), Rezaei, Nima^2,3,5 (AUTHOR) rezaei_nima@tums.ac.ir

Source: Journal of Translational Medicine. 2/28/2025, Vol. 23 Issue 1, p1-14. 14p.

Subject Terms: *DIABETIC cardiomyopathy, *CARDIAC arrest, *NON-coding RNA, *MEDICAL sciences, *TREATMENT effectiveness

BDH1 overexpression alleviates diabetic cardiomyopathy through inhibiting H3K9bhb-mediated transcriptional activation of LCN2.

Authors: Xu, Bu-tuo^1,2 (AUTHOR), Wan, Sheng-rong^3,4,5 (AUTHOR), Wu, Qi^6,7 (AUTHOR), Xing, Yi-hang^1,3 (AUTHOR), He, Yan-qiu^1,3 (AUTHOR), Huang, Wei^1,3 (AUTHOR), Long, Yang^3,4 (AUTHOR), Zhang, Chun-xiang³ (AUTHOR) zhangchx999@163.com, Xu, Yong^1,3,5 (AUTHOR) xywyll@aliyun.com, Jiang, Zong-zhe^1,3,5,8 (AUTHOR) jiangzongzhe555@126.com

Source: Cardiovascular Diabetology. 2/28/2025, Vol. 24 Issue 1, p1-18. 18p.

Subject Terms: *ORAL drug administration, *DIABETIC cardiomyopathy, *MEDICAL sciences, *ENZYME metabolism, *HEART fibrosis

Exercise in Diabetic Cardiomyopathy: Its Protective Effects and Molecular Mechanism.

Authors: Chen, Humin^1,2,3 (AUTHOR), Guo, Liang^1,2,3 (AUTHOR) guoliang@sus.edu.cn

Source: International Journal of Molecular Sciences. Feb2025, Vol. 26 Issue 4, p1465. 32p.

Subject Terms: *LEFT ventricular dysfunction, *DIABETIC cardiomyopathy, *KILLER cells, *CARDIOLOGICAL manifestations of general diseases, *REGULATORY T cells

PACS2/CPT1A/DHODH signaling promotes cardiomyocyte ferroptosis in diabetic cardiomyopathy.

Authors: Xiang, Hong^1,2 (AUTHOR), Lyu, Qi¹ (AUTHOR), Chen, Shuhua³ (AUTHOR), Ouyang, Jie⁴ (AUTHOR), Xiao, Di¹ (AUTHOR), Liu, Quanjun⁴ (AUTHOR), Long, HaiJiao⁴ (AUTHOR), Zheng, Xinru⁴ (AUTHOR), Yang, Xiaoping¹ (AUTHOR) Xiaoping.Yang@hunnu.edu.cn, Lu, Hongwei^2,4 (AUTHOR) hongweilu@csu.edu.cn

Source: Cardiovascular Diabetology. 12/4/2024, Vol. 23 Issue 1, p1-16. 16p.

Subject Terms: *DIABETIC cardiomyopathy, *IRON ions, *TYPE 2 diabetes, *REACTIVE oxygen species, *MYOCARDIUM

Diabetic Cardiomyopathy Uncovered: Transcriptomics, NLRP3, and Carvedilol Mechanisms.

Authors: Abudoureyimu, Alimujiang¹ (AUTHOR), Aihaiti, Alimu¹ (AUTHOR), Abudoujilili, Nuliman¹ (AUTHOR), Tuergong, Mayila¹ (AUTHOR), Adili, Guzainuer¹ (AUTHOR), Maimaiti, Maihebubaimu¹ (AUTHOR), Mohetaer, Dilinuer¹ (AUTHOR), Maiamaitishawuti, Yimamumaimaiti¹ (AUTHOR) imam@163.com, Iacobini, Carla¹ (AUTHOR) carla.iacobini@gmail.com

Source: Journal of Diabetes Research. 11/23/2024, Vol. 2024, p1-18. 18p.

Subject Terms: *DIABETIC cardiomyopathy, *CARVEDILOL, *NLRP3 protein, *TRANSCRIPTOMES, *PROTEIN expression

Preclinical evidence and possible mechanisms of cardioprotective effects of resveratrol in diabetic cardiomyopathy: a systematic review and meta-analysis.

Authors: Yan, Xiaodan¹ (AUTHOR), Hu, Youjia² (AUTHOR), Zhao, Shuyuan² (AUTHOR), Zhou, Qian¹ (AUTHOR), Chen, Qiu¹ (AUTHOR) chenqiu1005@cdutcm.edu.cn

Source: Diabetology & Metabolic Syndrome. 11/17/2024, Vol. 16 Issue 1, p1-15. 15p.

Subject Terms: *DIABETIC cardiomyopathy, *ANIMAL experimentation, *DIABETES complications, *HEART failure, *RESVERATROL

ZIP7 contributes to the pathogenesis of diabetic cardiomyopathy by suppressing mitophagy in mouse hearts.

Authors: Yang, Ningzhi¹ (AUTHOR), Zhang, Rui² (AUTHOR), Zhang, Hualu² (AUTHOR), Yu, Yonghao¹ (AUTHOR) yyh@tmu.edu.cn, Xu, Zhelong^1,2 (AUTHOR) zxu@tmu.edu.cn

Source: Cardiovascular Diabetology. 11/7/2024, Vol. 23 Issue 1, p1-15. 15p.

Subject Terms: *TYPE 2 diabetes, *DIABETIC cardiomyopathy, *ZINC transporters, *HEART diseases, *REACTIVE oxygen species

Author Correction: Myricitrin Alleviates Oxidative Stress-induced Inflammation and Apoptosis and Protects Mice against Diabetic Cardiomyopathy.

Authors: Zhang, Bin^1,2,3,4 (AUTHOR), Shen, Qiang⁵ (AUTHOR), Chen, Yaping⁶ (AUTHOR), Pan, Ruile¹ (AUTHOR), Kuang, Shihuan⁷ (AUTHOR), Liu, Guiyan⁶ (AUTHOR) gyliu@bit.edu.cn, Sun, Guibo^1,2,3,4 (AUTHOR) sunguibo@126.com, Sun, Xiaobo^1,2,3,4 (AUTHOR) sun_xiaobo163@163.com

Source: Scientific Reports. 11/4/2024, Vol. 14 Issue 1, p1-5. 5p.

Subject Terms: *PI3K/AKT pathway, *DIABETIC cardiomyopathy, *CELL analysis, *WESTERN immunoblotting, *NUCLEAR factor E2 related factor

Cellular Senescence: A Bridge Between Diabetes and Microangiopathy.

Authors: Liu, Jiahui¹ (AUTHOR) jhliu21@lzu.edu.cn, Guo, Buyu¹ (AUTHOR) guoby21@lzu.edu.cn, Liu, Qianqian¹ (AUTHOR) liuqq2020@lzu.edu.cn, Zhu, Guomao¹ (AUTHOR) zhugm18@lzu.edu.cn, Wang, Yaqi¹ (AUTHOR) wangyaqi19@lzu.edu.cn, Wang, Na¹ (AUTHOR) wangna2021@lzu.edu.cn, Yang, Yichen¹ (AUTHOR) yangyichen430@126.com, Fu, Songbo^2,3 (AUTHOR) fusb@lzu.edu.cn

Source: Biomolecules (2218-273X). Nov2024, Vol. 14 Issue 11, p1361. 20p.

Subject Terms: *DIABETIC cardiomyopathy, *DIABETIC nephropathies, *DIABETIC retinopathy, *PEOPLE with diabetes, *DIABETES, *CELLULAR aging

The role of nonmyocardial cells in the development of diabetic cardiomyopathy and the protective effects of FGF21: a current understanding.

Authors: Zhang, Tianyi¹ (AUTHOR), Jiang, Donghui¹ (AUTHOR), Zhang, Xiao¹ (AUTHOR), Chen, Ligang² (AUTHOR), Jiang, Jun^3,4 (AUTHOR), Zhang, Chunxiang^1,5 (AUTHOR) zhangchx2021@163.com, Li, Shengbiao^1,5 (AUTHOR) li-shengbiao@swmu.edu.cn, Li, Qiuhong¹ (AUTHOR) li-qiuhong@swmu.edu.cn

Source: Cell Communication & Signaling. 9/26/2024, Vol. 22 Issue 1, p1-23. 23p.

Subject Terms: *FIBROBLAST growth factors, *DIABETIC cardiomyopathy, *VASCULAR smooth muscle, *CARDIOMYOPATHIES, *MUSCLE cells

Identification of potential therapeutic targets for nonischemic cardiomyopathy in European ancestry: an integrated multiomics analysis.

Authors: Shi, Kaijia¹ (AUTHOR), Chen, Xu² (AUTHOR), Zhao, Yangyang¹ (AUTHOR), Li, Peihu¹ (AUTHOR), Chai, Jinxuan¹ (AUTHOR), Qiu, Jianmin¹ (AUTHOR), Shen, Zhihua³ (AUTHOR) shenzh@gdmu.edu.cn, Guo, Junli¹ (AUTHOR) guojl@muhn.edu.cn, Jie, Wei¹ (AUTHOR) wei_jie@muhn.edu.cn

Source: Cardiovascular Diabetology. 9/12/2024, Vol. 23 Issue 1, p1-12. 12p.

Subject Terms: *SMALL molecules, *DIABETIC cardiomyopathy, *HYPERTROPHIC cardiomyopathy, *GENE expression, *BLOOD proteins

Molecular Basis of Cardiomyopathies in Type 2 Diabetes.

Authors: Giardinelli, Silvia¹ (AUTHOR) silvia.giardinelli@edu.unife.it, Meliota, Giovanni² (AUTHOR) giovanni.meliota@gmail.com, Mentino, Donatella³ (AUTHOR) donatella.mentino@uniba.it, D'Amato, Gabriele⁴ (AUTHOR) gabriele.damato@asl.bari.it, Faienza, Maria Felicia³ (AUTHOR) mariafelicia.faienza@uniba.it

Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 15, p8280. 21p.

Subject Terms: *TYPE 2 diabetes, *DIABETIC cardiomyopathy, *HEART metabolism, *HEART failure, *INSULIN resistance

CircRNA_012164/MicroRNA-9-5p axis mediates cardiac fibrosis in diabetic cardiomyopathy.

Authors: Wang, Honglin¹ (AUTHOR), Wang, Eric Zi Rui¹ (AUTHOR), Feng, Biao¹ (AUTHOR) subrata.chakrabarti@schulich.uwo.ca, Chakrabarti, Subrata¹ (AUTHOR) subrata.chakrabarti@schulich.uwo.ca

Source: PLoS ONE. 7/23/2024, Vol. 19 Issue 7, p1-15. 15p.

Subject Terms: *DIABETIC cardiomyopathy, *HEART fibrosis, *CIRCULAR RNA, *NON-coding RNA, *GENE expression

Effect of extracellular matrix stiffness on efficacy of Dapagliflozin for diabetic cardiomyopathy.

Authors: Zhu, Tong^1,2,3 (AUTHOR), Ye, Zhaoyang^1,2 (AUTHOR), Song, Jingjing^1,2 (AUTHOR), Zhang, Junjie^1,2 (AUTHOR), Zhao, Yuxiang^1,2 (AUTHOR), Xu, Feng^1,2 (AUTHOR), Wang, Jun⁴ (AUTHOR), Huang, Xin⁵ (AUTHOR), Gao, Bin⁶ (AUTHOR) bingao@fmmu.edu.cn, Li, Fei^1,2 (AUTHOR) feili@mail.xjtu.edu.cn

Source: Cardiovascular Diabetology. 7/24/2024, Vol. 23 Issue 1, p1-16. 16p.

Subject Terms: *DIABETIC cardiomyopathy, *EXTRACELLULAR matrix, *MATRIX effect, *LABORATORY rats, *MYOCARDIAL injury

Insights into the Cardioprotective Effects of Pyridoxine Treatment in Diabetic Rats: A Study on Cardiac Oxidative Stress, Cardiometabolic Status, and Cardiovascular Biomarkers.

Authors: Mutavdzin Krneta, Slavica¹ (AUTHOR) jovanavjakovljevic@gmail.com, Gopcevic, Kristina² (AUTHOR) kristinagopcevic@yahoo.com, Stankovic, Sanja^3,4 (AUTHOR) sanjast2013@gmail.com, Jakovljevic Uzelac, Jovana¹ (AUTHOR) t.dusan@hotmail.com, Todorovic, Dušan¹ (AUTHOR) dr_djuric@yahoo.com, Labudovic Borovic, Milica⁵ (AUTHOR) sborovic2001@yahoo.com, Rakocevic, Jelena⁵ (AUTHOR) jelena.rakocevic@med.bg.ac.rs, Djuric, Dragan¹ (AUTHOR)

Source: Diagnostics (2075-4418). Jul2024, Vol. 14 Issue 14, p1507. 19p.

Subject Terms: *MALATE dehydrogenase, *DIABETIC cardiomyopathy, *LACTATE dehydrogenase, *VITAMIN B6, *SUPEROXIDE dismutase

Methanolic Extract of Phoenix Dactylifera Confers Protection against Experimental Diabetic Cardiomyopathy through Modulation of Glucolipid Metabolism and Cardiac Remodeling.

Authors: Nawaz, Laaraib¹ (AUTHOR) laaraibnawaz@gcuf.edu.pk, Grieve, David J.² (AUTHOR) d.grieve@qub.ac.uk, Muzaffar, Humaira¹ (AUTHOR) drhumairamuzaffar@gcuf.edu.pk, Iftikhar, Arslan¹ (AUTHOR) arslaniftikhar@gcuf.edu.pk, Anwar, Haseeb¹ (AUTHOR) drhaseebanwar@gcuf.edu.pk

Source: Cells (2073-4409). Jul2024, Vol. 13 Issue 14, p1196. 20p.

Subject Terms: *DATE palm, *DIABETIC cardiomyopathy, *BIOMARKERS, *GENE expression, *HEART failure

Identification of hub genes associated with diabetic cardiomyopathy using integrated bioinformatics analysis.

Authors: Cui, Hailong^1,2 (AUTHOR), Hu, Die³ (AUTHOR), Xu, Jing³ (AUTHOR), Zhao, Shuiying¹ (AUTHOR), Song, Yi^1,2 (AUTHOR), Qin, Guijun¹ (AUTHOR) hyqinggj@zzu.edu.cn, Liu, Yanling¹ (AUTHOR) lyl198611@163.com

Source: Scientific Reports. 7/3/2024, Vol. 14 Issue 1, p1-15. 15p.

Subject Terms: *DIABETIC cardiomyopathy, *CARDIAC hypertrophy, *MEMBRANE lipids, *RECEIVER operating characteristic curves, *GENE expression, *GENES, *LEFT ventricular hypertrophy

Mesenchymal stem cells ameliorate inflammation and pyroptosis in diabetic cardiomyopathy via the miRNA-223-3p/NLRP3 pathway.

Authors: Yang, Qu^1,2 (AUTHOR), Chen, Qi² (AUTHOR), Li, Sihui² (AUTHOR), Luo, Jun^1,2 (AUTHOR) luojun1786@163.com

Source: Diabetology & Metabolic Syndrome. 7/2/2024, Vol. 16 Issue 1, p1-15. 15p.

Subject Terms: *MESENCHYMAL stem cells, *DIABETIC cardiomyopathy, *PYROPTOSIS, *LYSIS, *TREATMENT effectiveness

Duodenal‐jejunal bypass surgery activates eNOS and enhances antioxidant system by activating AMPK pathway to improve heart oxidative stress in diabetic cardiomyopathy rats.

Authors: Yang, Guangwei¹ (AUTHOR), Liu, Zitian¹ (AUTHOR), Dong, Shuohui¹ (AUTHOR), Zhao, Xiang¹ (AUTHOR), Ge, Zheng¹ (AUTHOR), Cheng, Zhiqiang¹ (AUTHOR), Zhang, Xiang¹ (AUTHOR) xiang.zhang02@hotmail.com, Wang, Kexin¹ (AUTHOR) wkx3726@163.com

Source: Journal of Diabetes. Jul2024, Vol. 16 Issue 7, p1-17. 17p.

Subject Terms: *DIABETIC cardiomyopathy, *AMP-activated protein kinases, *TAKOTSUBO cardiomyopathy, *OXIDATIVE stress, *ADENOSINE monophosphate, *JEJUNOILEAL bypass, *LOW-fat diet

Roles of non-coding RNA in diabetic cardiomyopathy.

Authors: Yao, Xi¹ (AUTHOR), Huang, Xinyue² (AUTHOR), Chen, Jianghua¹ (AUTHOR), Lin, Weiqiang² (AUTHOR) wlin@zju.edu.cn, Tian, Jingyan^3,4 (AUTHOR) tianjypaper@163.com

Source: Cardiovascular Diabetology. 6/29/2024, Vol. 23 Issue 1, p1-13. 13p.

Subject Terms: *NON-coding RNA, *DIABETIC cardiomyopathy, *MICRORNA, *CIRCULAR RNA, *MOLECULAR biology