Nbeal2 knockout mice are not protected against hypoxia-induced pulmonary vascular remodeling and pulmonary hypertension

Authors: Posey, Janelle N. ^{1, 2}, Jordan, Mariah ^{1, 2}, Lewis, Caitlin V. ^{1, 3}, Sul, Christina ^{1, 3}, Dobrinskikh, Evgenia ^{1, 2}, Swindle, Delaney ^{1, 4}, Denorme, Frederik ⁵, Irwin, David ^{1, 4}, Di Paola, Jorge ⁶, Stenmark, Kurt ^{1, 3}, Nozik, Eva S. ^{1, 3}, Delaney, Cassidy ^{1, 2, ∗}

Source: In Blood Advances 8 April 2025 9(7):1571-1584

Deletion of tissue factor pathway inhibitor isoform beta or gamma, but not alpha, improves clotting in hemophilic mice

Authors: Eldem, Irem, Antunes-Heck, Lilian, Subramanian, Renumathi, Lasky, Nina M., Ashworth, Katrina, Di Paola, Jorge ^∗, Girard, Thomas J. ^∗

Source: In Journal of Thrombosis and Haemostasis October 2024 22(10):2681-2691

Type 1 VWD classification revisited: novel insights from combined analysis of the LoVIC and WiN studies

Authors: Atiq, Ferdows, Blok, Robin, van Kwawegen, Calvin B., Doherty, Dearbhla, Lavin, Michelle, van der Bom, Johanna G., O'Connell, Niamh M., de Meris, Joke, Ryan, Kevin, Schols, Saskia E. M., Byrne, Mary, Heubel-Moenen, Floor C. J. I., van Galen, Karin P. M., Preston, Roger J. S., Cnossen, Marjon H., Fijnvandraat, Karin, Baker, Ross I., Meijer, Karina, James, Paula, Di Paola, Jorge, Eikenboom, Jeroen, Leebeek, Frank W. G., O'Donnell, James S.

Source: In Blood 4 April 2024 143(14):1414-1424

D-dimer predicts venous thromboembolism in multiple myeloma: a nested case-control study

Authors: Sanfilippo, Kristen M., Fiala, Mark A., Feinberg, Daniel, Tathireddy, Harsha, Girard, Thomas, Vij, Ravi, Di Paola, Jorge, Gage, Brian F.

Source: In Research and Practice in Thrombosis and Haemostasis November 2023 7(8)

Characterization of copy-number variants in a large cohort of patients with von Willebrand disease reveals a relationship between disrupted regions and disease type

Authors: Sadler, Brooke, Christopherson, Pamela A., Perry, Crystal L., Bellissimo, Daniel B., Haberichter, Sandra L., Haller, Gabe, Antunes, Lilian, Flood, Veronica H., Di Paola, Jorge, Montgomery, Robert R.

Source: In Research and Practice in Thrombosis and Haemostasis October 2023 7(7)

A single F153Sβ3 mutation causes constitutive integrin αIIbβ3 activation in a variant form of Glanzmann thrombasthenia

Authors: Koukouritaki, Sevasti B., Thinn, Aye Myat M., Ashworth, Katrina J., Fang, Juan, Slater, Haley S., Du, Lily M., Nguyen, Huong Thi Thu, Pillois, Xavier, Nurden, Alan T., Ng, Christopher J., Di Paola, Jorge, Zhu, Jieqing, Wilcox, David A.

Source: In Blood Advances 11 July 2023 7(13):3180-3191

Heterogeneity in the half-life of factor VIII concentrate in patients with hemophilia A is due to variability in the clearance of endogenous von Willebrand factor

Authors: Elsheikh, Einas, Lavin, Michelle, Heck, Lilian Antunes, Larkin, Niamh, Mullaney, Brendan, Doherty, Dearbhla, Kennedy, Megan, Keenan, Catriona, Guest, Thomas, O'Mahony, Brian, Fazavana, Judicael, Fallon, Padraic G., Preston, Roger J.S., Gormley, John, Ryan, Kevin, O'Connell, Niamh M., Singleton, Evelyn, Byrne, Mary, McGowan, Mark, Roche, Sheila, Doyle, Mairead, Crowley, Maeve P., O'Shea, Susan I., Reipert, Birgit M., Johnsen, Jill M., Pipe, Steven W., Di Paola, Jorge, Turecek, Peter L., O'Donnell, James S.

Source: In Journal of Thrombosis and Haemostasis May 2023 21(5):1123-1134

Peripheral blood mononuclear cell tissue factor (F3 gene) transcript levels and circulating extracellular vesicles are elevated in severe coronavirus 2019 (COVID-19) disease

Authors: Girard, Thomas J., Antunes, Lilian, Zhang, Nan, Amrute, Junedh M., Subramanian, Renumathi, Eldem, Irem, Remy, Kenneth E., Mazer, Monty, Erlich, Emma C., Cruchaga, Carlos, Steed, Ashley L., Randolph, Gwendalyn J., Di Paola, Jorge

Source: In Journal of Thrombosis and Haemostasis March 2023 21(3):629-638

Enhanced VWF clearance in low VWF pathogenesis: limitations of the VWFpp/VWF:Ag ratio and clinical significance

Authors: Montgomery, R., Flood, V., Haberichter, S., Abshire, T., Weiler, H., Lillicrap, D., James, P., O’Donnell, J., Ng, C., Di Paola, J., Sadler, B., Bennett, C., Sidonio, R., Manco-Johnson, M., Journeycake, J., Zia, A., Lusher, J., Rajpurkar, M., Shapiro, A., Lentz, S., Gill, J., Leissinger, C., Ragni, M., Tarantino, M., Roberts, J., Doherty, Dearbhla, Lavin, Michelle, Byrne, Mary, Nolan, Margaret, O’Sullivan, Jamie M., Ryan, Kevin, O’Connell, Niamh M., Haberichter, Sandra L., Christopherson, Pamela A., Di Paola, Jorge, James, Paula D., O’Donnell, James S.

Source: In Blood Advances 14 February 2023 7(3):302-308

Safety and Tolerability of Intravenous Lidocaine Infusions as Opioid Adjunct for Children Hospitalized With Sickle Cell Vaso‐Occlusive Pain.

Authors: Agbakwuru, Ugochukwu, AuBuchon, Jacob D., Toebe, Bobi, LaBarge, Anne, Di Paola, Jorge, Hulbert, Monica L.

Source: Pediatric Blood & Cancer; Mar2025, Vol. 72 Issue 3, p1-4, 4p

Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors

Authors: Zhou, Chengjing, Uluisik, Rizvan, Rowley, Jesse W., David, Camille, Jones, Courtney L., Scharer, Christopher D., Noetzli, Leila, Fisher, Marlie H., Kirkpatrick, Gregory D., Bark, Katrina, Boss, Jeremy M., Henry, Curtis J., Pietras, Eric M., Di Paola, Jorge, Porter, Christopher C.

Source: In Experimental Hematology August-September 2022 112-113:24-34

Molecular pathogenesis and heterogeneity in type 3 VWD families in U.S. Zimmerman program

Authors: Christopherson, Pamela A. ^*, Haberichter, Sandra L., Flood, Veronica H., Perry, Crystal L., Sadler, Brooke E., Bellissimo, Daniel B., Di Paola, Jorge, Montgomery, Robert R., Abshire, T, Weiler, H, Lillicrap, D, James, P, O’Donnell, J, Ng, C, Bennett, C, Sidonio, R, Manco‐Johnson, M, Journeycake, J, Zia, A, Lusher, J, Rajpurkar, M, Shapiro, A, Lentz, S, Gill, J, Leissinger, C, Ragni, M, Tarantino, M, Roberts, J, Hord, J, Strouse, J, Ma, A, Valentino, L, Boggio, L, Sharathkumar, A, Gruppo, R, Kerlin, B, Kulkarni, R, Green, D, Hoots, K, Brown, D, Mahoney, D, Mathias, L, Bedros, A, Diamond, C, Neff, A, DiMichele, D, Giardina, P, Cohen, A, Paidas, M, Werner, E, Matsunaga, A, Shafer, F, Konkle, B, Cuker, A, Kouides, P, Stein, D

Source: In Journal of Thrombosis and Haemostasis July 2022 20(7):1576-1588

Genetics of inherited thrombocytopenias

Authors: Warren, Julia T., Di Paola, Jorge ^*

Source: In Blood 2 June 2022 139(22):3264-3277

Single-cell transcriptional analysis of human endothelial colony-forming cells from patients with low VWF levels

Authors: Ng, Christopher J. ^*, Liu, Alice, Venkataraman, Sujatha, Ashworth, Katrina J., Baker, Christopher D., O'Rourke, Rebecca, Vibhakar, Rajeev, Jones, Kenneth L., Di Paola, Jorge ^*

Source: In Blood 7 April 2022 139(14):2240-2251

Whole-exome analysis of adolescents with low VWF and heavy menstrual bleeding identifies novel genetic associations

Authors: Sadler, Brooke, Minard, Charles G., Haller, Gabe, Gurnett, Christina A., O'Brien, Sarah H., Wheeler, Allison, Jain, Shilpa, Sharma, Mutka, Zia, Ayesha, Kulkarni, Roshni, Mullins, Eric, Ragni, Margaret V., Sidonio, Robert, Dietrich, Jennifer E., Kouides, Peter A., Di Paola, Jorge ^*, Srivaths, Lakshmi ^*

Source: In Blood Advances 25 January 2022 6(2):420-428

Isotopically nonstationary 13C metabolic flux analysis in resting and activated human platelets

Authors: Sake, Cara L., Metcalf, Alexander J., Meagher, Michelle, Di Paola, Jorge, Neeves, Keith B., Boyle, Nanette R.

Source: In Metabolic Engineering January 2022 69:313-322

Hemostasis vs. homeostasis : Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation

Authors: Gupta, Shuchi, Konradt, Christoph, Corken, Adam, Ware, Jerry, Nieswandt, Bernhard, Di Paola, Jorge, Yu, Mei, Wang, Demin, Nieman, Marvin T., Whiteheart, Sidney W., Brass, Lawrence F.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Sep . 117(39), 24316-24325.

Access URL: https://www.jstor.org/stable/26969539

Bleeding assessment tools in the diagnosis of VWD in adults and children: a systematic review and meta-analysis of test accuracy

Authors: Kalot, Mohamad A. ¹, Husainat, Nedaa ², Tayiem, Sammy ³, El Alayli, Abdallah ⁴, Dimassi, Ahmad B. ⁵, Diab, Osama ⁶, Abughanimeh, Omar ⁷, Madoukh, Bader ⁸, Qureini, Aref ⁹, Ameer, Barbara ¹⁰, Di Paola, Jorge ¹¹, Eikenboom, Jeroen C.J. ¹², Jacobs-Pratt, Vicky ¹³, McLintock, Claire ¹⁴, Montgomery, Robert ^{15, 16}, O'Donnell, James S. ¹⁷, Sidonio, Robert, Jr. ¹⁸, Brignardello-Petersen, Romina ¹⁹, Flood, Veronica ¹⁶, Connell, Nathan T. ²⁰, James, Paula D. ²¹, Mustafa, Reem A. ^{3, 4, 19, *}

Source: In Blood Advances 14 December 2021 5(23):5023-5031

Diagnostic approach to the patient with a suspected inherited platelet disorder: Who and how to test

Authors: Perez Botero, Juliana, Di Paola, Jorge ^*

Source: In Journal of Thrombosis and Haemostasis September 2021 19(9):2127-2136

Negatively charged nanoparticles of multiple materials inhibit shear-induced platelet accumulation

Authors: Griffin, Michael T., Ashworth, Katrina, Hill, Nathaniel, von Behren, Jaydra, Di Paola, Jorge, Ku, David N.

Source: In Nanomedicine: Nanotechnology, Biology, and Medicine July 2021 35