Hyaluronic acid-based hydrogels loaded with chemoattractant and anticancer drug – new formulation for attracting and tackling glioma cellsElectronic supplementary information (ESI) available. See DOI: 10.1039/d1sm01003d

Authors: Kasapidou, Paraskevi M., de Montullé, Emmanuel Laillet, Dembélé, Kleouforo-Paul, Mutel, Alexandre, Desrues, Laurence, Gubala, Vladimir, Castel, Hélène

Source: Soft matter. 17(48):10846-10861

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156260573.0x000001&indx=1&recIds=ETOCvdc_100156260573.0x000001

Chemotactic cell migration: the core autophagy protein ATG9A is at the leading edge

Authors: Campisi, Daniele, Desrues, Laurence, Dembélé, Kleouforo-Paul, Mutel, Alexandre, Parment, Renaud, Gandolfo, Pierrick, Castel, Hélène, Morin, Fabrice

Source: Autophagy. 18(12):3037-3039

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165439943.0x000001&indx=1&recIds=ETOCvdc_100165439943.0x000001

Urantide Improves Cardiac Function, Modulates Systemic Cytokine Response, and Increases Survival in A Murine Model of Endotoxic Shock

Authors: Clavier, Thomas, Besnier, Emmanuel, Maucotel, Julie, Arabo, Arnaud, Desrues, Laurence, El Amki, Mohamad, Perzo, Nicolas, Richard, Vincent, Tamion, Fabienne, Gandolfo, Pierrick, Dubois, Martine, Castel, Hélène, Compère, Vincent

Source: Shock. 54(4):574-582

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181579101.0x000001&indx=1&recIds=ETOCvdc_100181579101.0x000001

The urotensin II receptor triggers an early meningeal response and a delayed macrophage-dependent vasospasm after subarachnoid hemorrhage in male mice.

Authors: Pedard, Martin, Prevost, Lucie, Carpena, Camille, Holleran, Brian, Desrues, Laurence, Dubois, Martine, Nicola, Celeste, Gruel, Roxane, Godefroy, David, Deffieux, Thomas, Tanter, Mickael, Ali, Carine, Leduc, Richard, Prézeau, Laurent, Gandolfo, Pierrick, Morin, Fabrice, Wurtz, Olivier, Bonnard, Thomas, Vivien, Denis, Castel, Hélène

Source: Nature Communications; 9/29/2024, Vol. 15 Issue 1, p1-27, 27p

Subject Terms: CEREBRAL vasospasm, SUBARACHNOID hemorrhage, CEREBRAL ischemia, COGNITION disorders, TREATMENT effectiveness

Sexual Disorders of Patients With Metastatic Renal Cell Carcinoma (mRCC) Treated With Antiangiogenic Therapies

Authors: Denouel, Angeline, Heutte, Natacha, Escudier, Bernard, Kurtz, Jean-Emmanuel, Dos Santos, Melanie, Longato, Nadine, Desrues, Laurence, Dauchy, Sarah, Lange, Marie, Sevin, Emmanuel, Rieux, Chantal, Clarisse, Benedicte, Castel, Helene, Noal, Sabien, Joly, Florence

Source: In Clinical Genitourinary Cancer October 2018 16(5):369-375

Association between vasoactive peptide urotensin II in plasma and cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a potential therapeutic target

Authors: Clavier, Thomas, Mutel, Alexandre, Desrues, Laurence, Lefevre-Scelles, Antoine, Gastaldi, Gioia, El Amki, Mohamad, Dubois, Martine, Melot, Anthony, Wurtz, Véronique, Curey, Sophie

Source: Journal of neurosurgery. 131(4):1278-1288

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621579689&indx=1&recIds=ETOCRN621579689

Prospective Evaluation of the Impact of Antiangiogenic Treatment on Cognitive Functions in Metastatic Renal Cancer

Authors: Joly, Florence, Heutte, Natacha, Duclos, Brigitte, Noal, Sabine, Léger-Hardy, Isabelle, Dauchy, Sarah, Longato, Nadine, Desrues, Laurence, Houede, Nadine, Lange, Marie, Sevin, Emmanuel, Rieux, Chantal, Clarisse, Bénédicte, Castel, Hélène, Escudier, Bernard

Source: In European Urology Focus 15 December 2016 2(6):642-649

Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis

Authors: Coly, Pierre-Michaël, Perzo, Nicolas, Le Joncour, Vadim, Lecointre, Céline, Schouft, Marie-Thérèse, Desrues, Laurence, Tonon, Marie-Christine, Wurtz, Olivier, Gandolfo, Pierrick, Castel, Hélène, Morin, Fabrice

Source: Autophagy. 12(12):2344-2362

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100038403411.0x000001&indx=1&recIds=ETOCvdc_100038403411.0x000001

Analysis of the melanotrope cell neuroendocrine interface in two amphibian species, Rana ridibunda and Xenopus laevis: A celebration of 35 years of collaborative research

Authors: Jenks, Bruce G., Galas, Ludovic, Kuribara, Miyuki, Desrues, Laurence, Kidane, Adhanet H., Vaudry, Hubert, Scheenen, Wim J.J.M., Roubos, Eric W., Tonon, Marie-Christine

Source: In General and Comparative Endocrinology 2011 170(1):57-67

The core autophagy protein ATG9A controls dynamics of cell protrusions and directed migration

Authors: Campisi, Daniele, Desrues, Laurence, Dembélé, Kléouforo-Paul, Mutel, Alexandre, Parment, Renaud, Gandolfo, Pierrick, Castel, Hélène, Morin, Fabrice

Source: Journal of cell biology. 221(3):e202106014-e202106014

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN628870103&indx=1&recIds=ETOCRN628870103

Effects of Side Chain and Peptide Bond Modifications on the Targeting Properties of Stabilized Minigastrin Analogs.

Authors: Zavvar, Taraneh Sadat, Hörmann, Anton Amadeus, Klingler, Maximilian, Summer, Dominik, Rangger, Christine, Desrues, Laurence, Castel, Hélène, Gandolfo, Pierrick, von Guggenberg, Elisabeth

Source: Pharmaceuticals (14248247); Feb2023, Vol. 16 Issue 2, p278, 17p

Subject Terms: PEPTIDE bonds, PEPTIDE receptors, PEPTIDES, PEPTIDE derivatives, CHEMICAL properties

Effect of GABA A receptor activation on UT-coupled signaling pathways in rat cortical astrocytes

Authors: Desrues, Laurence, Lefebvre, Thomas, Diallo, Mickaël, Gandolfo, Pierrick, Leprince, Jérôme, Chatenet, David, Vaudry, Hubert, Tonon, Marie-Christine, Castel, Hélène

Source: In Peptides 2008 29(5):727-734

[Orn 5]URP acts as a pure antagonist of urotensinergic receptors in rat cortical astrocytes

Authors: Diallo, Mickaël, Jarry, Marie, Desrues, Laurence, Castel, Hélène, Chatenet, David, Leprince, Jérôme, Vaudry, Hubert, Tonon, Marie-Christine, Gandolfo, Pierrick

Source: In Peptides 2008 29(5):813-819

A Panax quinquefolius -Based Preparation Prevents the Impact of 5-FU on Activity/Exploration Behaviors and Not on Cognitive Functions Mitigating Gut Microbiota and Inflammation in Mice.

Authors: Parment, Renaud, Dubois, Martine, Desrues, Laurence, Mutel, Alexandre, Dembélé, Kléouforo-Paul, Belin, Nicolas, Tron, Laure, Guérin, Charlène, Coëffier, Moïse, Compère, Vincent, Féger, Céline, Joly, Florence, Hilber, Pascal, Ribet, David, Castel, Hélène

Source: Cancers; Sep2022, Vol. 14 Issue 18, pN.PAG-N.PAG, 38p

Subject Terms: PROTEIN metabolism, COGNITION disorders, CELL differentiation, CYTOKINES, INTERLEUKINS, CEREBRAL hemispheres, NEURONS, GUT microbiome, INFLAMMATION, ANIMAL experimentation, FLUOROURACIL, NEUROINFLAMMATION, CANCER fatigue, CELL proliferation, LACTOBACILLUS, GINSENG, MICE

The regulation of α-MSH release by GABA is mediated by a chloride-dependent [Ca 2+] c increase in frog melanotrope cells

Authors: Desrues, Laurence, Castel, Hélène, Malagon, Maria M., Vaudry, Hubert ^*, Tonon, Marie-Christine

Source: In Peptides 2005 26(10):1936-1943

Stabilization Strategies for Linear Minigastrin Analogues: Further Improvements via the Inclusion of Proline into the Peptide Sequence.

Authors: Klingler, Maximilian, Hörmann, Anton A., Rangger, Christine, Desrues, Laurence, Castel, Hélène, Gandolfo, Pierrick, von Guggenberg, Elisabeth

Source: Journal of Medicinal Chemistry; 12/10/2020, Vol. 63 Issue 23, p14668-14679, 12p

Down-Regulation of GABAA Receptor via Promiscuity with the Vasoactive Peptide Urotensin II Receptor. Potential Involvement in Astrocyte Plasticity.

Authors: Desrues, Laurence^1,2, Lefebvre, Thomas^1,2, Lecointre, Céline^1,2, Schouft, Marie-Thérèse^1,2, Leprince, Jérôme^1,2, Compère, Vincent^1,2,3, Morin, Fabrice^1,2, Proust, François^1,2,4, Gandolfo, Pierrick^1,2, Tonon, Marie-Christine^1,2, Castel, Hé lène^1,2 helene.castel@univ-rouen.fr

Source: PLoS ONE. May2012, Vol. 7 Issue 5, p1-22. 22p.

Subject Terms: *ASTROCYTES, *CELLS, *NEUROGLIA, *BIOMOLECULES, *MICROBIAL genetics, *CELL membranes, *ASTROCYTOMAS, *MEMBRANE proteins

Stabilization Strategies for Linear Minigastrin Analogues: Further Improvements viathe Inclusion of Proline into the Peptide Sequence

Authors: Klingler, Maximilian, Hörmann, Anton A., Rangger, Christine, Desrues, Laurence, Castel, Hélène, Gandolfo, Pierrick, von Guggenberg, Elisabeth

Source: Journal of Medicinal Chemistry; December 2020, Vol. 63 Issue: 23 p14668-14679, 12p

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Development of Novel 111-In-Labelled DOTA Urotensin II Analogues for Targeting the UT Receptor Overexpressed in Solid Tumours.

Authors: Poret, Benjamin^1,2,3 (AUTHOR) Marc-Andre.Bonin@USherbrooke.ca, Desrues, Laurence^1,2,4 (AUTHOR) laurence.desrues@univ-rouen.fr, Bonin, Marc-André³ (AUTHOR) Richard.Leduc@USherbrooke.ca, Pedard, Martin^1,4 (AUTHOR) martin.pedard@univ-rouen.fr, Dubois, Martine^1,4 (AUTHOR) martine.dubois@univ-rouen.fr, Leduc, Richard³ (AUTHOR), Modzelewski, Romain^2,4 (AUTHOR) pierre.vera@chb.unicancer.fr, Decazes, Pierre^2,4 (AUTHOR) pierre.bohn@chb.unicancer.fr, Morin, Fabrice^1,2,4 (AUTHOR) fabrice.morin@univ-rouen.fr, Vera, Pierre^2,4 (AUTHOR), Castel, Hélène^1,4 (AUTHOR) helene.castel@univ-rouen.fr, Bohn, Pierre^2,4 (AUTHOR), Gandolfo, Pierrick^1,4 (AUTHOR)

Source: Biomolecules (2218-273X). Mar2020, Vol. 10 Issue 3, p471. 1p.

Subject Terms: *G protein coupled receptors, *TUMORS, *STEREOLITHOGRAPHY, *BREAST, *PROXIMAL kidney tubules, *ANIMAL models in research, *INTRAVENOUS injections