Integrative scATAC-seq and scRNA-seq analyses map thymic iNKT cell development and identify Cbfβ for its commitment

Authors: Jie Wang, Indra Adrianto, Kalpana Subedi, Tingting Liu, Xiaojun Wu, Qijun Yi, Ian Loveless, Congcong Yin, Indrani Datta, Derek B. Sant’Angelo, Mitchell Kronenberg, Li Zhou, Qing-Sheng Mi

Source: Cell Discovery, Vol 9, Iss 1, Pp 1-20 (2023)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2056-5968

Access URL: https://doaj.org/article/a8b94dfc61f84bf081361ad310518709

A SARS-CoV-2 Vaccine Designed for Manufacturability Results in Unexpected Potency and Non-Waning Humoral Response

Authors: Elliot Campbell, Julie Dobkin, Louis J. Osorio, Afsal Kolloli, Santhamani Ramasamy, Ranjeet Kumar, Derek B. Sant’Angelo, Selvakumar Subbian, Lisa K. Denzin, Stephen Anderson

Source: Vaccines, Vol 11, Iss 4, p 832 (2023)

Subject Terms: SARS-CoV-2, COVID-19, vaccine, durable immunity, emerging variants, protection, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/11/4/832; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/364d92019a5e4bfe87e369e8880765c8

Histone deacetylase 3 is required for iNKT cell development

Authors: Puspa Thapa, Sinibaldo Romero Arocha, Ji Young Chung, Derek B. Sant’Angelo, Virginia Smith Shapiro

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/bb0b26a9f24f4d3983eb28ce34699aa4

Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus.

Authors: Masako Osada, Varan J Singh, Kenmin Wu, Derek B Sant'Angelo, Mark Pezzano

Source: PLoS ONE, Vol 8, Iss 12, p e83024 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3858364?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ee1124e72b5249a19e877d5010a1aed2

TCR affinity for self-ligands influences the development and function of encephalitogenic T cells.

Authors: Jianwei Li, Omar Vandal, Derek B Sant'Angelo

Source: PLoS ONE, Vol 6, Iss 3, p e17702 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3060088?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e3376cda76d346cd9da3c6eae1b99b00

Altered development of NKT cells, γδ T cells, CD8 T cells and NK cells in a PLZF deficient patient.

Authors: Maggie Eidson, Justin Wahlstrom, Aimee M Beaulieu, Bushra Zaidi, Steven E Carsons, Peggy K Crow, Jianda Yuan, Jedd D Wolchok, Bernhard Horsthemke, Dagmar Wieczorek, Derek B Sant'Angelo

Source: PLoS ONE, Vol 6, Iss 9, p e24441 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3167854?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3484e0fde264494f96fa665042b2b439

Ectopic T cell receptor-α locus control region activity in B cells is suppressed by direct linkage to two flanking genes at once.

Authors: Stefan Knirr, Janette Gomos-Klein, Blanca E Andino, Faith Harrow, Karl F Erhard, Damian Kovalovsky, Derek B Sant'Angelo, Benjamin D Ortiz

Source: PLoS ONE, Vol 5, Iss 11, p e15527 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2989920?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e7cc039b8043455cba6a8db9a542484b

Selective depletion of eosinophils or neutrophils in mice impacts the efficiency of apoptotic cell clearance in the thymus.

Authors: Hye-Jung Kim, Eric S Alonzo, Guillaume Dorothee, Jeffrey W Pollard, Derek B Sant'Angelo

Source: PLoS ONE, Vol 5, Iss 7, p e11439 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2897847?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/4c0dbdff5d6043f697390bbee09b397b

A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway.

Authors: Damian Kovalovsky, Mark Pezzano, Benjamin D Ortiz, Derek B Sant'Angelo

Source: PLoS ONE, Vol 5, Iss 1, p e8675 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2800196?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/24ea7fcdeded467db479f5656282a528