Involvement of NF-κB1 and the Non-canonical NF-κB Signaling Pathway in the Pathogenesis of Acute Kidney Injury in Shiga-toxin-2-induced Hemolytic-uremic Syndrome in Mice

Authors: Sobbe, Isabelle V., Krieg, Nadine, Dennhardt, Sophie, Coldewey, Sina M.

Source: Shock. 56(4):573-581

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181585228.0x000001&indx=1&recIds=ETOCvdc_100181585228.0x000001

Transition from acute kidney injury to chronic kidney disease in a long-term murine model of Shiga toxin-induced hemolytic-uremic syndrome.

Authors: Wegener, Jamila, Dennhardt, Sophie, Loeffler, Ivonne, Coldewey, Sina M.

Source: Frontiers in Immunology; 2024, p1-12, 12p

Subject Terms: RENAL fibrosis, HEMOLYTIC-uremic syndrome, CHRONIC kidney failure, ACUTE kidney failure, HEMOLYTIC anemia

Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms

Authors: Dennhardt, Sophie, Finke, Karl R., Huwiler, Andrea, Coldewey, Sina M.

Source: In BBA - Molecular Basis of Disease 1 April 2019 1865(4):774-781

The Role of the N-Terminal Domain of Thrombomodulin and the Potential of Recombinant Human Thrombomodulin as a Therapeutic Intervention for Shiga Toxin-Induced Hemolytic-Uremic Syndrome.

Authors: Kröller, Sarah, Schober, Jana, Krieg, Nadine, Dennhardt, Sophie, Pirschel, Wiebke, Kiehntopf, Michael, Conway, Edward M., Coldewey, Sina M.

Source: Toxins; Sep2024, Vol. 16 Issue 9, p409, 13p

Subject Terms: THROMBOTIC thrombocytopenic purpura, HEMOLYTIC-uremic syndrome, ACUTE kidney failure, THROMBOMODULIN, ENDOTHELIAL cells

Deletion of Sphingosine Kinase 2 Attenuates Acute Kidney Injury in Mice with Hemolytic-Uremic Syndrome.

Authors: Müller, Tina, Krieg, Nadine, Lange-Polovinkin, Antonia I., Wissuwa, Bianka, Gräler, Markus H., Dennhardt, Sophie, Coldewey, Sina M.

Source: International Journal of Molecular Sciences; Jul2024, Vol. 25 Issue 14, p7683, 21p

Subject Terms: SPHINGOSINE kinase, HEMOLYTIC-uremic syndrome, ACUTE kidney failure, MICE, KIDNEY diseases, TOXINS, DIABETIC nephropathies

Cell-free DNA in patients with sepsis: long term trajectory and association with 28-day mortality and sepsis-associated acute kidney injury.

Authors: Dennhardt, Sophie, Ceanga, Iuliana-Andreea, Baumbach, Philipp, Amiratashani, Mona, Kröller, Sarah, Coldewey, Sina M.

Source: Frontiers in Immunology; 2024, p1-13, 13p

Subject Terms: CIRCULATING tumor DNA, CELL-free DNA, ACUTE kidney failure, SEPSIS, CYTOCHROME oxidase, INTENSIVE care patients

Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors

Authors: De Lucia, Daniela, Lucio, Oscar Méndez, Musio, Biagia, Bender, Andreas, Listing, Monika, Dennhardt, Sophie, Koeberle, Andreas, Garscha, Ulrike, Rizzo, Roberta, Manfredini, Stefano, Werz, Oliver, Ley, Steven V.

Source: In European Journal of Medicinal Chemistry 28 August 2015 101:573-583

Corrigendum to 'Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms' [Biochim. Biophys. Acta Mol. Basis Dis. 2019 Apr 1;1865(4):774–781]

Authors: Dennhardt, Sophie, Finke, Karl R., Huwiler, Andrea, Coldewey, Sina M.

Source: Biochimica et biophysica acta. 1866(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128474082.0x000001&indx=1&recIds=ETOCvdc_100128474082.0x000001

Corrigendum to 'Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors' [Eur. J. Med. Chem. 101 (2015) 573–583]

Authors: de Lucia, Daniela, Lucio, Oscar Méndez, Musio, Biagia, Bender, Andreas, Listing, Monika, Dennhardt, Sophie, Koeberle, Andreas, Garscha, Ulrike, Rizzo, Roberta, Manfredini, Stefano, Werz, Oliver, Ley, Steven V.

Source: European journal of medicinal chemistry. 103:223-225

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100039283485.0x000001&indx=1&recIds=ETOCvdc_100039283485.0x000001

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