STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment

Authors: Ramadhin, Anisha R. ^{1, 6}, Lee, Shun-Hsiao ^{2, 6}, Zhou, Di ¹, Salmazo, Anita ⁴, Gonzalo-Hansen, Camila ¹, van Sluis, Marjolein ¹, Blom, Cindy M.A. ¹, Janssens, Roel C. ¹, Raams, Anja ¹, Dekkers, Dick ³, Bezstarosti, Karel ³, Slade, Dea ⁵, Vermeulen, Wim ¹, Pines, Alex ¹, Demmers, Jeroen A.A. ³, Bernecky, Carrie ⁴, Sixma, Titia K. ^{2, ∗}, Marteijn, Jurgen A. ^{1, 7, ∗∗}

Source: In Molecular Cell 19 December 2024 84(24):4740-4757

Lentiviral gene therapy with IGF2-tagged GAA normalizes the skeletal muscle proteome in murine Pompe disease

Authors: Liang, Qiushi, Vlaar, Eva C., Pijnenburg, Joon M., Rijkers, Erikjan, Demmers, Jeroen A.A., Vulto, Arnold G., van der Ploeg, Ans T., van Til, Niek P., Pijnappel, W.W.M. Pim

Source: In Journal of Proteomics 16 January 2024 291

Live cell transcription-coupled nucleotide excision repair dynamics revisited

Authors: Llerena Schiffmacher, Diana A., Kliza, Katarzyna W., Theil, Arjan F., Kremers, Gert-Jan, Demmers, Jeroen A.A., Ogi, Tomoo, Vermeulen, Michiel, Vermeulen, Wim, Pines, Alex

Source: In DNA Repair October 2023 130

Ubiquitinome Profiling Reveals in Vivo UBE2D3 Targets and Implicates UBE2D3 in Protein Quality Control

Authors: Yalçin, Zeliha, Koot, Daniëlle, Bezstarosti, Karel, Salas-Lloret, Daniel, Bleijerveld, Onno B., Boersma, Vera, Falcone, Mattia, González-Prieto, Román, Altelaar, Maarten, Demmers, Jeroen A.A., Jacobs, Jacqueline J.L.

Source: In Molecular & Cellular Proteomics June 2023 22(6)

Tumor decellularization reveals proteomic and mechanical characteristics of the extracellular matrix of primary liver cancer

Authors: van Tienderen, Gilles S., Conboy, James, Muntz, Iain, Willemse, Jorke, Tieleman, Jantine, Monfils, Kathryn, Schurink, Ivo J., Demmers, Jeroen A.A., Doukas, Michail, Koenderink, Gijsje H., van der Laan, Luc J.W., Verstegen, Monique M.A.

Source: In Biomaterials Advances March 2023 146

A ubiquitinome analysis to study the functional roles of the proteasome associated deubiquitinating enzymes USP14 and UCH37

Authors: van der Wal, Lennart, Bezstarosti, Karel, Demmers, Jeroen A.A.

Source: In Journal of Proteomics 30 June 2022 262

An evolutionarily ancient mechanism for regulation of hemoglobin expression in vertebrate red cells

Authors: Miyata, Masato ^{1, *}, Gillemans, Nynke ^{1, *}, Hockman, Dorit ^{2, 3, *}, Demmers, Jeroen A.A. ⁴, Cheng, Jan-Fang ⁵, Hou, Jun ⁶, Salminen, Matti ⁷, Fisher, Christopher A. ⁸, Taylor, Stephen ⁹, Gibbons, Richard J. ⁸, Ganis, Jared J. ¹⁰, Zon, Leonard I. ¹⁰, Grosveld, Frank ¹, Mulugeta, Eskeatnaf ¹, Sauka-Spengler, Tatjana ², Higgs, Douglas R. ^{2, 8}, Philipsen, Sjaak ^{1, 1}

Source: In Blood 16 July 2020 136(3):269-278

A proteome comparison between human fetal and mature renal extracellular matrix identifies EMILIN1 as a regulator of renal epithelial cell adhesion

Authors: Louzao-Martinez, Laura, van Dijk, Christian G.M., Xu, Yan Juan, Korn, Amber, Bekker, Nicolaas J., Brouwhuis, Romi, Nicese, Maria Novella, Demmers, Jeroen A.A., Goumans, Marie-José T.H., Masereeuw, Rosalinde, Duncker, Dirk J., Verhaar, Marianne C., Cheng, Caroline

Source: In Matrix Biology Plus November 2019 4

Improvement of ubiquitylation site detection by Orbitrap mass spectrometry

Authors: van der Wal, Lennart, Bezstarosti, Karel, Sap, Karen A., Dekkers, Dick H.W., Rijkers, Erikjan, Mientjes, Edwin, Elgersma, Ype, Demmers, Jeroen A.A.

Source: In Journal of Proteomics 10 February 2018 172:49-56

Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases

Authors: van Erp, Susan, van den Heuvel, Dianne M.A., Fujita, Yuki, Robinson, Ross A., Hellemons, Anita J.C.G.M., Adolfs, Youri, Van Battum, Eljo Y., Blokhuis, Anna M., Kuijpers, Marijn, Demmers, Jeroen A.A., Hedman, Håkan, Hoogenraad, Casper C., Siebold, Christian, Yamashita, Toshihide, Pasterkamp, R. Jeroen

Source: In Developmental Cell 7 December 2015 35(5):537-552

Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function

Authors: Meinders, Marjolein, Kulu, Divine I., van de Werken, Harmen J.G., Hoogenboezem, Mark, Janssen, Hans, Brouwer, Rutger W.W., van Ijcken, Wilfred F.J., Rijkers, Erik-Jan, Demmers, Jeroen A.A., Krüger, Imme, van den Berg, Timo K., Suske, Guntram, Gutiérrez, Laura, Philipsen, Sjaak

Source: In Blood 19 March 2015 125(12):1957-1967

Nucleotide Biosynthetic Enzyme GMP Synthase Is a TRIM21-Controlled Relay of p53 Stabilization

Authors: Reddy, B. Ashok, van der Knaap, Jan A., Bot, Alice G.M., Mohd-Sarip, Adone, Dekkers, Dick H.W., Timmermans, Mieke A., Martens, John W.M., Demmers, Jeroen A.A., Verrijzer, C. Peter

Source: In Molecular Cell 6 February 2014 53(3):458-470

Activin A Suppresses Osteoblast Mineralization Capacity by Altering Extracellular Matrix (ECM) Composition and Impairing Matrix Vesicle (MV) Production

Authors: Alves, Rodrigo D.A.M. ^‡, Eijken, Marco ^‡, Bezstarosti, Karel ^§, Demmers, Jeroen A.A. ^§, van Leeuwen, Johannes P.T.M. ^{‡, ¶}

Source: In Molecular & Cellular Proteomics October 2013 12(10):2890-2900

An immunoaffinity purification method for the proteomic analysis of ubiquitinated protein complexes

Authors: Schwertman, Petra, Bezstarosti, Karel, Laffeber, Charlie, Vermeulen, Wim, Demmers, Jeroen A.A., Marteijn, Jurgen A.

Source: In Analytical Biochemistry 15 September 2013 440(2):227-236

DNA dependent recruitment of DDX17 and other interacting proteins by the human androgen receptor

Authors: Wong, Hao Yun ^⁎, Demmers, Jeroen A.A., Bezstarosti, Karel, Grootegoed, J. Anton, Brinkmann, Albert O.

Source: In BBA - Proteins and Proteomics February 2009 1794(2):193-198

Histone Chaperones ASF1 and NAP1 Differentially Modulate Removal of Active Histone Marks by LID-RPD3 Complexes during NOTCH Silencing

Authors: Moshkin, Yuri M., Kan, Tsung Wai, Goodfellow, Henry, Bezstarosti, Karel, Maeda, Robert K., Pilyugin, Maxim, Karch, Francois, Bray, Sarah J., Demmers, Jeroen A.A., Verrijzer, C. Peter

Source: In Molecular Cell 2009 35(6):782-793

RAD51AP1 Is a Structure-Specific DNA Binding Protein that Stimulates Joint Molecule Formation during RAD51-Mediated Homologous Recombination

Authors: Modesti, Mauro, Budzowska, Magda, Baldeyron, Céline, Demmers, Jeroen A.A., Ghirlando, Rodolfo, Kanaar, Roland

Source: In Molecular Cell 9 November 2007 28(3):468-481

Proteomics Analysis of Ring1B/Rnf2 Interactors Identifies a Novel Complex with the Fbxl10/Jhdm1B Histone Demethylase and the Bcl6 Interacting Corepressor

Authors: Sánchez, Carmen ^{‡, §}, Sánchez, Inés ^{‡, ¶}, Demmers, Jeroen A.A. ^‖, Rodriguez, Patrick ^**, Strouboulis, John ^{**, ‡‡}, Vidal, Miguel ^{‡, §§}

Source: In Molecular & Cellular Proteomics May 2007 6(5):820-834

HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis

Authors: Brandsma, Inger, Sato, Koichi, van Rossum-Fikkert, Sari E., van Vliet, Nicole, Sleddens, Esther, Reuter, Marcel, Odijk, Hanny, van den Tempel, Nathalie, Dekkers, Dick H.W., Bezstarosti, Karel, Demmers, Jeroen A.A., Maas, Alex, Lebbink, Joyce, Wyman, Claire, Essers, Jeroen, van Gent, Dik C., Baarends, Willy M., Knipscheer, Puck, Kanaar, Roland, Zelensky, Alex N.

Source: In Cell Reports 25 June 2019 27(13):3790-3798

High-Throughput Proteomics Identifies THEMIS2 As Biomarker of Inferior Treatment-Free Survival in Chronic Lymphocytic Leukemia

Authors: Hengeveld, Paul, Kolijn, Pieter M. ^*, Demmers, Jeroen A.A. ^*, Doff, Wouter ^*, Dubois, Julie M.N. ^*, Rijken, Melissa ^*, Assmann, Jorn ^*, Van Der Straten, Lina ^*, Boiten, Henk-Jan ^*, Gussinklo, Kirsten J. ^*, Valk, Peter J.M., Westerweel, Peter E. ^*, Kater, Arnon P., Langerak, Anton W. ^*, Levin, Mark-David

Source: In Blood 15 November 2022 140 Supplement 1:9851-9852