D2HGDH Deficiency Regulates Seizures through GSH/Prdx6/ROS‐Mediated Excitatory Synaptic Activity

Authors: Zhijuan Zhang, Hui Zhang, Peng Zhang, Rong Li, Jinyu Zhou, Jiyuan Li, Danmei Hu, Rui Huang, Fenglin Tang, Jie Liu, Demei Xu, Chenlu Zhang, Xin Tian, Yuanlin Ma, Patrick Kwan

Source: Advanced Science, Vol 12, Iss 13, Pp n/a-n/a (2025)

Subject Terms: D‐2‐hydroxyglutarate dehydrogenase, epilepsy, excitatory synapses, reactive oxygen species, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/c8e6e54fde6e4297a8774be816abfc35

GSDMD knockdown attenuates phagocytic activity of microglia and exacerbates seizure susceptibility in TLE mice

Authors: Xiaoxia Yang, Qingqing Cao, Yi Guo, Jingchuan He, Demei Xu, Aolei Lin

Source: Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)

Subject Terms: GSDMD, Pyroptosis, Phagocytic activity of microglia, P2Y12R, Temporal lobe epilepsy, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/c94783463c234aeea3322f64df4301ac

Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampusResearch in Context

Authors: Qin Yang, Zifeng Huang, Yangfu Luo, Fangshuo Zheng, Yida Hu, Hui Liu, Shuzhen Zhu, Miaoqing He, Demei Xu, Yun Li, Min Yang, Yi Yang, Xiaobo Wei, Xiaoya Gao, Wei Wang, Junhong Ma, Yuanlin Ma, Xuefeng Wang, Qing Wang

Source: EBioMedicine, Vol 47, Iss , Pp 470-483 (2019)

Subject Terms: Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396419305705; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/6da0a74d7fee487a89a78bf7d57cbca6

Inhibition of Cgkii Suppresses Seizure Activity and Hippocampal Excitation by Regulating the Postsynaptic Delivery of Glua1

Authors: Juan Gu, Xin Tian, Wei Wang, Qin Yang, Peijia Lin, Yuanlin Ma, Yan Xiong, Demei Xu, Yanke Zhang, Yong Yang, Shanshan Lu, Zijun Lin, Jing Luo, Fei Xiao, Xuefeng Wang

Source: Cellular Physiology and Biochemistry, Vol 46, Iss 1, Pp 160-177 (2018)

Subject Terms: 4-aminopyridine, CGKII, Epilepsy, GluA1, Pilocarpine, Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/488419; https://doaj.org/toc/1015-8987; https://doaj.org/toc/1421-9778

Access URL: https://doaj.org/article/6cf96d7c68fc4b2799921b6e4be7b6f6

PolychlorinatedBiphenyl Quinone Induces EndoplasmicReticulum Stress, Unfolded Protein Response, and Calcium Release.

Authors: Demei Xu¹, Chuanyang Su¹, Xiufang Song¹, Qiong Shi¹, Juanli Fu¹, Lihua Hu¹, Xiaomin Xia¹, Erqun Song¹, Yang Song¹

Source: Chemical Research in Toxicology. Jun2015, Vol. 28 Issue 6, p1326-1337. 12p.

Subject Terms: *POLYCHLORINATED biphenyls, *QUINONE, *ENDOPLASMIC reticulum, *PHYSIOLOGICAL stress, *DENATURATION of proteins, *CALCIUM, *PHYSIOLOGY

Tetrachlorobenzoquinone Activates Nrf2 Signaling by Keap1 Cross-Linking and Ubiquitin Translocation but Not Keap1-Cullin3 Complex Dissociation.

Authors: Chuanyang Su, Pu Zhang, Xiufang Song, Qiong Shi, Juanli Fu, Xiaomin Xia, Huiyuan Bai, Lihua Hu, Demei Xu, Erqun Song, Yang Song

Source: Chemical Research in Toxicology; Apr2015, Vol. 28 Issue 4, p765-774, 10p

Internal Mechanism Analysis of Modeling on Particles Size Distribution Characteristics of Impact Attrition Beryllium Powders.

Authors: Lijun He, Demei Xu, Nan Hu, Tingting Li, Jingming Zhong, Min Luo

Source: Rare Metal Materials & Engineering; Mar2014, Vol. 43 Issue 3, p567-569, 3p

TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation.

Authors: Haiqing Zhang, Xin Tian, Xi Lu, Demei Xu, Yi Guo, Zhifang Dong, Yun Li, Yuanlin Ma, Chengzhi Chen, Yong Yang, Min Yang, Yi Yang, Feng Liu, Ruijiao Zhou, Miaoqing He, Fei Xiao, Xuefeng Wang, Zhang, Haiqing (AUTHOR), Tian, Xin (AUTHOR), Lu, Xi (AUTHOR)

Source: Journal of Clinical Investigation. Sep2019, Vol. 129 Issue 9, p3864-3876. 13p.

Subjects: METHYL aspartate receptors, GLUTAMATE receptors, EPILEPSY, MEMBRANE proteins, PROTEIN expression, NEURONS, ENDOSOMES

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