Intratumoral Cell Neighborhoods Coordinate Outcomes in Pancreatic Ductal Adenocarcinoma

Authors: Wattenberg, Max M., Colby, Sarah, Garrido-Laguna, Ignacio, Xue, Yuqing, Chang, Renee, Delman, Devora, Lee, Jesse, Affolter, Kajsa, Mulvihill, Sean J., Beg, M. Shaalan, Wang-Gillam, Andrea, Wade, James Lloyd, III, Guthrie, Katherine A., Chiorean, E. Gabriela, Ahmad, Syed A., Lowy, Andrew M., Philip, Philip Agop, Sohal, Davendra P.S., Beatty, Gregory L.

Source: In Gastroenterology June 2024 166(6):1114-1129

Multimodal immune phenotyping reveals microbial-T cell interactions that shape pancreatic cancer

Authors: Li, Yan, Chang, Renee B., Stone, Meredith L., Delman, Devora, Markowitz, Kelly, Xue, Yuqing, Coho, Heather, Herrera, Veronica M., Li, Joey H., Zhang, Liti, Choi-Bose, Shaanti, Giannone, Michael, Shin, Sarah M., Coyne, Erin M., Hernandez, Alexei, Gross, Nicole E., Charmsaz, Soren, Ho, Won Jin, Lee, Jae W., Beatty, Gregory L.

Source: In Cell Reports Medicine 20 February 2024 5(2)

EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models

Authors: Porazzi, Patrizia ^{1, 2, 3, 8}, Nason, Siena ^{1, 2, 3, 8}, Yang, Ziqi ^{1, 2, 3}, Carturan, Alberto ^{1, 2, 3}, Ghilardi, Guido ^{1, 2, 3}, Guruprasad, Puneeth ^{1, 2, 3}, Patel, Ruchi P. ^{1, 2, 3}, Tan, Melody ^{1, 2, 3, 4}, Padmanabhan, Anushka Anant ^{1, 2, 3}, Lemoine, Jean ^{1, 2, 3}, Fardella, Eugenio ^{1, 2, 5}, Zhang, Yunlin ^{1, 2, 3}, Pajarillo, Raymone ^{1, 2, 3}, Chen, Linhui ^{1, 2, 3}, Ugwuanyi, Ositadimma ^{1, 2, 3}, Markowitz, Kelly ², Delman, Devora ², Angelos, Mathew G. ^{1, 2, 3}, Shestova, Olga ^{1, 2}, Isshiki, Yusuke ⁶, Blanchard, Tatiana ¹, Béguelin, Wendy ⁶, Melnick, Ari M. ⁶, Linette, Gerald P. ^{1, 4}, Beatty, Gregory L. ^{2, 7}, Carreno, Beatriz M. ^{1, 4}, Cohen, Ivan J. ^{1, 2, 3}, Paruzzo, Luca ^{1, 2, 3}, Schuster, Stephen J. ^{1, 2, 3}, Ruella, Marco ^{1, 2, 3, 9, ∗}

Source: In Cancer Cell 10 March 2025 43(3):537-551

Hepatocytes direct the formation of a pro-metastatic niche in the liver

Authors: Lee, Jae, Stone, Meredith, Porrett, Paige, Thomas, Stacy, Komar, Chad, Li, Joey, Delman, Devora, Graham, Kathleen, Gladney, Whitney, Hua, Xia, Black, Taylor, Chien, Austin, Majmundar, Krishna, Thompson, Jeffrey, Yee, Stephanie, O'Hara, Mark, Aggarwal, Charu, Xin, Dong, Shaked, Abraham, Gao, Mingming, Liu, Dexi, Borad, Mitesh, Ramanathan, Ramesh, Carpenter, Erica, Ji, Ailing, Beer, Maria, Beer, Frederick, Webb, Nancy, Beatty, Gregory

Source: Nature. 567(7747):249-252

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127967284.0x000001&indx=1&recIds=ETOCvdc_100127967284.0x000001

Effects of Flaxseed Lignan Secoisolariciresinol Diglucosideon Preneoplastic Biomarkers of Cancer Progression in a Model of Simultaneous Breast and Ovarian Cancer Development

Authors: Delman, Devora M., Fabian, Carol J., Kimler, Bruce F., Yeh, Henry, Petroff, Brian K.

Source: Nutrition and cancer. 67(5):857-864

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCETOCvdc_100026903388.0x000001&indx=1&recIds=ETOCETOCvdc_100026903388.0x000001

Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice.

Authors: Thomas, Stacy K., Wattenberg, Max M., Choi-Bose, Shaanti, Uhlik, Mark, Harrison, Ben, Coho, Heather, Cassella, Christopher R., Stone, Meredith L., Patel, Dhruv, Markowitz, Kelly, Delman, Devora, Chisamore, Michael, Drees, Jeremy, Bose, Nandita, Beatty, Gregory L.

Source: Nature Communications; 10/10/2023, Vol. 14 Issue 1, p1-17, 17p

Subject Terms: KUPFFER cells, LIVER metastasis, PANCREATIC duct, T cells, LIVER cancer, CANCER invasiveness

Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins

Authors: Stone, Meredith L., Lee, Jesse, Lee, Jae W., Coho, Heather, Tariveranmoshabad, Mito, Wattenberg, Max M., Choi, Hana, Herrera, Veronica M., Xue, Yuqing, Choi-Bose, Shaanti, Zingone, Sofia K., Patel, Dhruv, Markowitz, Kelly, Delman, Devora, Balachandran, Vinod P., Beatty, Gregory L.

Source: Nature Immunology; 20240101, Issue: Preprints p1-9, 9p

Ex vivo activity of BCL-2 family inhibitors ABT-199 and ABT-737 combined with 5-azacytidine in myeloid malignancies.

Authors: Bogenberger, James M.¹ (AUTHOR), Delman, Devora¹ (AUTHOR), Hansen, Nanna¹ (AUTHOR), Valdez, Riccardo² (AUTHOR), Fauble, Veena¹ (AUTHOR), Mesa, Ruben A.¹ (AUTHOR), Tibes, Raoul¹ (AUTHOR) tibes.raoul@mayo.edu

Source: Leukemia & Lymphoma. Jan2015, Vol. 56 Issue 1, p226-229. 4p.

Subject Terms: *AZACITIDINE, *MYELOID leukemia

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

Identification and Mechanistic Characterization of CMPD1 As a Selective Sensitizer of Histone Deacetylase Inhibitors in Myeloid Malignancies

Authors: Bogenberger, James M, Hansen, Nanna ^*, Delman, Devora ^*, Mesa, Ruben A., Tibes, Raoul

Source: In Blood 3 December 2015 126(23):3689-3689

The Hedgehog Pathway As Targetable Vulnerability with 5-Azacitidine in MDS and AML

Authors: Tibes, Raoul, Delman, Devora ^*, Hansen, Nanna ^*, Gowin, Krisstina L. ^*, Mesa, Ruben, Bogenberger, James M

Source: In Blood 6 December 2014 124(21):4612-4612

MK2a Substrate-Selective p38 Inhibitor CMPD1 Selectively Synergizes with HDAC Inhibitors in CD34+ Cells from Myeloid Malignancies

Authors: Bogenberger, James M, Hansen, Nanna ^*, Delman, Devora ^*, Mesa, Ruben A., Tibes, Raoul

Source: In Blood 6 December 2014 124(21):2239-2239

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

MK2a Substrate-Selective p38 Inhibitor CMPD1 Selectively Synergizes with HDAC Inhibitors in CD34+Cells from Myeloid Malignancies

Authors: Bogenberger, James M, Hansen, Nanna, Delman, Devora, Mesa, Ruben A., Tibes, Raoul

Source: Blood; November 2014, Vol. 124 Issue: 21 p2239-2239, 1p