Chromatin Landscape Governing Murine Epidermal Differentiation

Authors: Nayak, Subhashree, Jiang, Kan, Hope, Emma, Cross, Michael, Overmiller, Andrew, Naz, Faiza, Worrell, Stephen, Bajpai, Deepti, Hasneen, Kowser, Brooks, Stephen R., Dell’Orso, Stefania, Morasso, Maria I.

Source: In Journal of Investigative Dermatology July 2023 143(7):1220-1232

Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling

Authors: Feng, Xuesong, Wang, A. Hongjun, Juan, Aster H., Ko, Kyung Dae, Jiang, Kan, Riparini, Giulia, Ciuffoli, Veronica, Kaba, Aissah, Lopez, Christopher, Naz, Faiza, Jarnik, Michal, Aliberti, Elizabeth, Hu, Shenyuan, Segalés, Jessica, Khateb, Mamduh, Acevedo-Luna, Natalia, Randazzo, Davide, Cheung, Tom H., Muñoz-Cánoves, Pura, Dell’Orso, Stefania, Sartorelli, Vittorio

Source: In Developmental Cell 19 June 2023 58(12):1052-1070

Transcriptomics, regulatory syntax, and enhancer identification in mesoderm-induced ESCs at single-cell resolution

Authors: Khateb, Mamduh, Perovanovic, Jelena, Ko, Kyung Dae, Jiang, Kan, Feng, Xuesong, Acevedo-Luna, Natalia, Chal, Jérome, Ciuffoli, Veronica, Genzor, Pavol, Simone, James, Haase, Astrid D., Pourquié, Olivier, Dell’Orso, Stefania, Sartorelli, Vittorio

Source: In Cell Reports 16 August 2022 40(7)

Optimized methods for scRNA-seq and snRNA-seq of skeletal muscle stored in nucleic acid stabilizing preservative.

Authors: Heuston, Elisabeth F., Doumatey, Ayo P., Naz, Faiza, Islam, Shamima, Anderson, Stacie, Kirby, Martha R., Wincovitch, Stephen, Dell'Orso, Stefania, Rotimi, Charles N., Adeyemo, Adebowale A.

Source: Communications Biology; 1/5/2025, Vol. 8 Issue 1, p1-9, 9p

Subject Terms: CELL nuclei, CYTOLOGY, LIFE sciences, SKELETAL muscle, RNA sequencing

Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism

Authors: Gupta, Sarthak, Nakabo, Shuichiro, Blanco, Luz P., O’Neil, Liam J., Wigerblad, Gustaf, Goel, Rishi R., Mistry, Pragnesh, Jiang, Kan, Carmona-Rivera, Carmelo, Chan, Diana W., Wang, Xinghao, Pedersen, Hege L., Gadkari, Manasi, Howe, Katherine N., Naz, Faiza, Dell’Orso, Stefania, Hasni, Sarfaraz A., Dempsey, Caeden, Buscetta, Ashley, Frischmeyer-Guerrerio, Pamela A., Kruszka, Paul, Muenke, Maximilian, Franco, Luis M., Sun, Hong-Wei, Kaplan, Mariana J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jul . 117(28), 16481-16491.

Access URL: https://www.jstor.org/stable/26935242

Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

Authors: Bresciani, Erica, Carrington, Blake, Yu, Kai, Kim, Erika M., Zhen, Tao, Guzman, Victoria Sanchez, Broadbridge, Elizabeth, Bishop, Kevin, Kirby, Martha, Harper, Ursula, Wincovitch, Stephen, Dell'Orso, Stefania, Sartorelli, Vittorio, Sood, Raman, Liu, Paul ^*

Source: In Blood Advances 14 December 2021 5(23):4949-4962

The circadian clock gene BMAL1 modulates autoimmunity features in lupus.

Authors: Nakabo, Shuichiro, Sandoval-Heglund, Donavon, Hanata, Norio, Brooks, Stephen, Hoffmann, Victoria, Zhang, Mingzeng, Ambler, William, Manna, Zerai, Poncio, Elaine, Hasni, Sarfaraz, Islam, Shamima, Dell'Orso, Stefania, Kaplan, Mariana J.

Source: Frontiers in Immunology; 2024, p1-15, 15p

Subject Terms: ARYL hydrocarbon receptors, CLOCK genes, SYSTEMIC lupus erythematosus, IMMUNE complexes, BONE marrow

Pathological autoantibody internalisation in myositis.

Authors: Pinal-Fernandez, Iago, Muñoz-Braceras, Sandra, Casal-Dominguez, Maria, Pak, Katherine, Torres-Ruiz, Jiram, Musai, Jon, Dell'Orso, Stefania, Naz, Faiza, Islam, Shamima, Gutierrez-Cruz, Gustavo, Dolores Cano, Maria, Matas-Garcia, Ana, Padrosa, Joan, Tobias-Baraja, Ester, Garrabou, Gloria, Aldecoa, Iban, Espinosa, Gerard, Simeon-Aznar, Carmen Pilar, Guillen-Del-Castillo, Alfredo, Gil-Vila, Albert

Source: Annals of the Rheumatic Diseases; Nov2024, Vol. 83 Issue 11, p1549-1560, 77p

A Multiomic Analysis to Identify Drivers of Subclinical Vascular Disease in Systemic Lupus Erythematosus.

Authors: Oliveira, Christopher, Temesgen‐Oyelakin, Yenealem, Naqi, Mohammad, Davis, Michael, Naz, Faiza, Dell'Orso, Stefania, Brooks, Stephen, Kuhn, Skyler, Hill, Tom, Li, Xiaobai, Patel, Nidhi, Parel, Philip, Gadina, Massimo, Gupta, Sarthak, Mehta, Nehal, Hasni, Sarfaraz A., Kaplan, Mariana J.

Source: Arthritis & Rheumatology; Oct2024, Vol. 76 Issue 10, p1501-1511, 11p

Subject Terms: RISK assessment, PROTEINS, RESEARCH funding, RADIOPHARMACEUTICALS, MULTIOMICS, DEOXY sugars, SYSTEMIC lupus erythematosus, DESCRIPTIVE statistics, CARDIOVASCULAR disease diagnosis, PROTEOMICS, EMISSION-computed tomography, VASCULAR diseases, DISEASE progression, BIOMARKERS, SEQUENCE analysis, INTERLEUKINS, TUMOR necrosis factors, EVALUATION, DISEASE risk factors

Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus

Authors: Mistry, Pragnesh, Nakabo, Shuichiro, O’Neil, Liam, Goel, Rishi R., Jiang, Kan, Carmona-Rivera, Carmelo, Gupta, Sarthak, Chan, Diana W., Carlucci, Philip M., Wang, Xinghao, Naz, Faiza, Manna, Zerai, Dey, Amit, Mehta, Nehal N., Hasni, Sarfaraz, Dell’Orso, Stefania, Gutierrez-Cruz, Gustavo, Sun, Hong-Wei, Kaplan, Mariana J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Dec 01. 116(50), 25222-25228.

Access URL: https://www.jstor.org/stable/26862043

A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans

Authors: Tsai, Pei-Fang, Dell’Orso, Stefania, Rodriguez, Joseph, Vivanco, Karinna O., Ko, Kyung-Dae, Jiang, Kan, Juan, Aster H., Sarshad, Aishe A., Vian, Laura, Tran, Michelle, Wangsa, Darawalee, Wang, A. Hongjun, Perovanovic, Jelena, Anastasakis, Dimitrios, Ralston, Evelyn, Ried, Thomas, Sun, Hong-Wei, Hafner, Markus, Larson, Daniel R., Sartorelli, Vittorio

Source: In Molecular Cell 5 July 2018 71(1):129-141

MiR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate

Authors: Ji, Yun, Fioravanti, Jessica, Zhu, Wei, Wang, Hongjun, Wu, Tuoqi, Hu, Jinhui, Lacey, Neal, Gautam, Sanjivan, Le Gall, John, Yang, Xia, Hocker, James, Escobar, Thelma, He, Shan, Dell'Orso, Stefania, Hawk, Nga, Kapoor, Veena, Telford, William, Di Croce, Luciano, Muljo, Stefan, Zhang, Yi, Sartorelli, Vittorio, Gattinoni, Luca

Source: Nature communications. 10(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138345365.0x000001&indx=1&recIds=ETOCvdc_100138345365.0x000001

The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins

Authors: Wang, A. Hongjun, Juan, Aster H., Ko, Kyung Dae, Tsai, Pei-Fang, Zare, Hossein, Dell’Orso, Stefania, Sartorelli, Vittorio

Source: In Molecular Cell 19 October 2017 68(2):398-413

The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1

Authors: Dell’Orso, Stefania, Wang, A. Hongjun, Shih, Han-Yu, Saso, Kayoko, Berghella, Libera, Gutierrez-Cruz, Gustavo, Ladurner, Andreas G., O’Shea, John J., Sartorelli, Vittorio, Zare, Hossein

Source: In Cell Reports 9 February 2016 14(5):1156-1168

Genetic Risk Factors for Early-Onset Merkel Cell Carcinoma.

Authors: Mohsin, Noreen, Hunt, Devin, Yan, Jia, Jabbour, Austin J., Nghiem, Paul, Choi, Jaehyuk, Zhang, Yue, Freeman, Alexandra F., Bergerson, Jenna R. E., Dell'Orso, Stefania, Lachance, Kristina, Kulikauskas, Rima, Collado, Loren, Cao, Wenjia, Lack, Justin, Similuk, Morgan, Seifert, Bryce A., Ghosh, Rajarshi, Walkiewicz, Magdalena A., Brownell, Isaac

Source: JAMA Dermatology; Feb2024, Vol. 160 Issue 2, p172-178, 7p

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

Authors: Ryall, James G., Dell’Orso, Stefania, Derfoul, Assia, Juan, Aster, Zare, Hossein, Feng, Xuesong, Clermont, Daphney, Koulnis, Miroslav, Gutierrez-Cruz, Gustavo, Fulco, Marcella, Sartorelli, Vittorio

Source: In Cell Stem Cell 5 February 2015 16(2):171-183

The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1

Authors: Dell'Orso, Stefania, Wang, A. Hongjun, Shih, Han-Yu, Saso, Kayoko, Berghella, Libera, Gutierrez-Cruz, Gustavo, Ladurner, Andreas G., O'Shea, John J., Sartorelli, Vittorio, Zare, Hossein

Source: Cell reports. 14(5):1156-1168

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100062392810.0x000001&indx=1&recIds=ETOCvdc_100062392810.0x000001

Psat1-generated α-ketoglutarate and glutamine promote muscle stem cell activation and regeneration

Authors: Ciuffoli, Veronica, Feng, Xuesong, Jiang, Kan, Acevedo-Luna, Natalia, Ko, Kyung Dae, Wang, A. Hong Jun, Riparini, Giulia, Khateb, Mamduh, Glancy, Brian, Dell'Orso, Stefania, Sartorelli, Vittorio

Source: Genes & Development; 2024, Vol. 38 Issue: 3-4 p151-167, 17p

eRNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci

Authors: Mousavi, Kambiz, Zare, Hossein, Dell’Orso, Stefania, Grontved, Lars, Gutierrez-Cruz, Gustavo, Derfoul, Assia, Hager, Gordon L., Sartorelli, Vittorio

Source: In Molecular Cell 12 September 2013 51(5):606-617

Identification of Unique microRNA Profiles in Different Types of Idiopathic Inflammatory Myopathy.

Authors: Muñoz-Braceras, Sandra, Pinal-Fernandez, Iago, Casal-Dominguez, Maria, Pak, Katherine, Milisenda, José César, Lu, Shajia, Gadina, Massimo, Naz, Faiza, Gutierrez-Cruz, Gustavo, Dell'Orso, Stefania, Torres-Ruiz, Jiram, Grau-Junyent, Josep Maria, Selva-O'Callaghan, Albert, Paik, Julie J., Albayda, Jemima, Christopher-Stine, Lisa, Lloyd, Thomas E., Corse, Andrea M., Mammen, Andrew L.

Source: Cells (2073-4409); Sep2023, Vol. 12 Issue 17, p2198, 13p

Subject Terms: INCLUSION body myositis, TYPE I interferons, GENE expression, MUSCLE diseases, MICRORNA