De novo synthesis of 1-phenethylisoquinoline in engineered Escherichia coli

Authors: Yaping Mao, Jiangming Zhu, Qian Zhang, Guangyi Wang, Hongkai Fan, Xiaowei Zhang, Yuwei Sun, Yong Wang

Source: Synthetic and Systems Biotechnology, Vol 10, Iss 1, Pp 271-280 (2025)

Subject Terms: Phenylethylisoquinoline alkaloids, 1-Phenethylisoquinoline, De novo biosynthesis, Escherichia coli, Reductases, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405805X24001376; https://doaj.org/toc/2405-805X

Access URL: https://doaj.org/article/46ccc8e928344da0badcfe73fca5a9c0

Total saponin extracts of Pseudostellaria heterophylla ameliorates meibomian gland dysfunction through SCD1/SPT1/ceramide axis

Authors: Du, Qiyue ^{a, b, 1}, Yang, Jiayong ^{a, d, 1}, Zhou, Bangyan ^{a, b}, Zeng, Wenxuan ^{a, b}, Huang, Rui ^{b, c}, Zhao, Yun ^{b, c}, Ren, Jie ^{a, b, c, ⁎⁎}, Qiu, Yan ^{a, b, c, ⁎}

Source: In Journal of Ethnopharmacology 27 February 2025 342

Possible Metabolic Remodeling based on de novo Biosynthesis of L-serine in Se-Subtoxic or -Deficient Mammals

Authors: Wang, Jianrong ^{1, †}, Zhang, Xue ^{1, †}, Zhan, Shuo ¹, Han, Feng ¹, Wang, Qin ¹, Liu, Yiqun ^{1, ⁎}, Huang, Zhenwu ^{1, 2, ⁎⁎}

Source: In The Journal of Nutrition January 2025 155(1):9-26

Efficient carbon flux allocation towards D-pantothenic acid production via growth-decoupled strategy in Escherichia coli

Authors: Wang, Yihong ^{a, b}, Zhou, Junping ^{a, b}, Zhang, Zheng ^{a, b}, Huang, Lianggang ^{a, b}, Zhang, Bo ^{a, b}, Liu, Zhiqiang ^{a, b, ⁎}, Zheng, Yuguo ^{a, b}

Source: In Bioresource Technology November 2024 411

Metabolic engineering strategies for de novo biosynthesis of sterols and steroids in yeast

Authors: Yuehao Gu, Xue Jiao, Lidan Ye, Hongwei Yu

Source: Bioresources and Bioprocessing, Vol 8, Iss 1, Pp 1-14 (2021)

Subject Terms: Sterols and steroids, De novo biosynthesis, Yeast, Metabolic engineering, Technology, Chemical technology, TP1-1185, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://doaj.org/toc/2197-4365

Access URL: https://doaj.org/article/dba4a53dfd57415fa9604740d4e524e9

Engineering the C3N Pathway as a Short Detour for De Novo NAD+ Biosynthesis in Saccharomyces cerevisiae

Authors: Xinli Li, Yue Tang, Yong Ding, Pengwei Li, Yihua Chen

Source: Fermentation, Vol 9, Iss 10, p 886 (2023)

Subject Terms: C3N pathway, NAD+ de novo biosynthesis, Saccharomyces cerevisiae, eukaryotes, Fermentation industries. Beverages. Alcohol, TP500-660

File Description: electronic resource

Relation: https://www.mdpi.com/2311-5637/9/10/886; https://doaj.org/toc/2311-5637

Access URL: https://doaj.org/article/f6fc1319ce4a47fc8bf9d35ce3b74441

De novo biosynthesis of C-arabinosylated flavones by utilization of indica rice C-glycosyltransferases

Authors: Zhuo Chen, Yuwei Sun, Guangyi Wang, Ying Zhang, Qian Zhang, Yulian Zhang, Jianhua Li, Yong Wang

Source: Bioresources and Bioprocessing, Vol 8, Iss 1, Pp 1-13 (2021)

Subject Terms: De novo biosynthesis, C-Arabinoside flavone, C-Glycosyltransferase, Rice, Technology, Chemical technology, TP1-1185, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://doaj.org/toc/2197-4365

Access URL: https://doaj.org/article/8816421d99934729b47a6a982e43f537

Heterologous biosynthesis of isobavachalcone in tobacco based on in planta screening of prenyltransferases

Authors: Lirong Guo, Wei Zhao, Yan Wang, Yu Yang, Cuimei Wei, Jian Guo, Jianye Dai, Masami Yokota Hirai, Aike Bao, Zhigang Yang, Haijuan Chen, Yimeng Li

Source: Frontiers in Plant Science, Vol 13 (2022)

Subject Terms: isobavachalcone, prenyltransferase, prenylflavonoids, de novo biosynthesis, multigene expression vector, plant metabolic engineering, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpls.2022.1034625/full; https://doaj.org/toc/1664-462X

Access URL: https://doaj.org/article/33d5f07e51c548a0926258bedb1f5da3

Efficient production of anthocyanins in Saccharomyces cerevisiae by introducing anthocyanin transporter and knocking out endogenous degrading enzymes

Authors: Sha Xu, Guangjian Li, Jingwen Zhou, Guicai Chen, Jianzhong Shao

Source: Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)

Subject Terms: anthocyanins, degrading enzyme, Saccharomyces cerevisiae, transporter, de novo biosynthesis, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2022.899182/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/aac66852381b4e9aaccc6c0d8def6e42

De Novo Synthesis of Poly(3-hydroxybutyrate-co-3-hydroxypropionate) from Oil by Engineered Cupriavidus necator

Authors: Mengdi Li, Wei Li, Tongtong Zhang, Keyi Guo, Dexin Feng, Fengbing Liang, Chao Xu, Mo Xian, Huibin Zou

Source: Bioengineering, Vol 10, Iss 4, p 446 (2023)

Subject Terms: biopolyester, poly(3-hydroxypropionate-co-3-hydroxybutyrate), engineered Cupriavidus necator, de novo biosynthesis, oil substrates, Technology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2306-5354/10/4/446; https://doaj.org/toc/2306-5354

Access URL: https://doaj.org/article/c49072252ee540c891a78a7d66633501

Enhanced Production of Pterostilbene in Escherichia coli Through Directed Evolution and Host Strain Engineering

Authors: Zhi-Bo Yan, Jing-Long Liang, Fu-Xing Niu, Yu-Ping Shen, Jian-Zhong Liu

Source: Frontiers in Microbiology, Vol 12 (2021)

Subject Terms: pterostilbene, de novo biosynthesis, directed evolution, genome engineering, Escherichia coli, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2021.710405/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/469dc820ef9a4846b5589105dc694946

Construction of an Artificial Biosynthetic Pathway for the Styrylpyrone Compound 11-Methoxy-Bisnoryangonin Produced in Engineered Escherichia coli

Authors: Kyung Taek Heo, Byeongsan Lee, Jae-Hyuk Jang, Jung-Oh Ahn, Young-Soo Hong

Source: Frontiers in Microbiology, Vol 12 (2021)

Subject Terms: styrylpyrone, 11-methoxy-bisnoryangonin, styrylpyrone synthase, de novo biosynthesis, type III PKS, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2021.714335/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/aa273e2b230449399d47c6159b1262f4

Optimizing the Timeframe to Produce Polychaetes (Hediste diversicolor) Enriched With Essential Fatty Acids Under Different Combinations of Temperature and Salinity

Authors: Daniel Jerónimo, Ana Isabel Lillebø, Felisa Rey, Henrique Koga Ii, M. Rosário M. Domingues, Ricardo Calado

Source: Frontiers in Marine Science, Vol 8 (2021)

Subject Terms: de novo biosynthesis, n-3 HUFA, POM bioremediation, ragworms, extractive species, Science, General. Including nature conservation, geographical distribution, QH1-199.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmars.2021.671545/full; https://doaj.org/toc/2296-7745

Access URL: https://doaj.org/article/10914d0b044f4685a6a3423eebead44e

Engineering an Alcohol-Forming Fatty Acyl-CoA Reductase for Aldehyde and Hydrocarbon Biosynthesis in Saccharomyces cerevisiae

Authors: Jee Loon Foo, Bahareh Haji Rasouliha, Adelia Vicanatalita Susanto, Susanna Su Jan Leong, Matthew Wook Chang

Source: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)

Subject Terms: synthetic biology, metabolic engineering, protein engineering, de novo biosynthesis, biofuels, aldehydes, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fbioe.2020.585935/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/f9c13df89b434bf7ba1d5c2a8fad8f66

Mechanism-Driven Metabolic Engineering for Bio-Based Production of Free R-Lipoic Acid in Saccharomyces cerevisiae Mitochondria

Authors: Binbin Chen, Jee Loon Foo, Hua Ling, Matthew Wook Chang

Source: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)

Subject Terms: lipoic acid, Saccharomyces cerevisiae, metabolic engineering, lipoamidase, de novo biosynthesis, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fbioe.2020.00965/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/b70b1667f84b4727a7bf72f533fc9c8b

Metabolic engineering of Ashbya gossypii for deciphering the de novo biosynthesis of γ-lactones

Authors: Rui Silva, Tatiana Q. Aguiar, Eduardo Coelho, Alberto Jiménez, José Luis Revuelta, Lucília Domingues

Source: Microbial Cell Factories, Vol 18, Iss 1, Pp 1-11 (2019)

Subject Terms: Volatile organic compounds, γ-Lactones, Ashbya gossypii, De novo biosynthesis, Metabolic engineering, Fatty acid biosynthesis, Microbiology, QR1-502

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12934-019-1113-1; https://doaj.org/toc/1475-2859

Access URL: https://doaj.org/article/4dca400208b545ffb6ab3f5928609ed5

Inhibitors of Nucleotide Biosynthesis as Candidates for a Wide Spectrum of Antiviral Chemotherapy

Authors: Claudia Soledad Sepúlveda, Cybele Carina García, Elsa Beatriz Damonte

Source: Microorganisms, Vol 10, Iss 8, p 1631 (2022)

Subject Terms: wide-spectrum antiviral, host-targeted antiviral, nucleotide metabolism, de novo biosynthesis pathway, salvage pathway, pyrimidines, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2607/10/8/1631; https://doaj.org/toc/2076-2607

Access URL: https://doaj.org/article/102aa6419fad4a04aacbf1c2f15afaa5

Microbial Biosynthesis of Lactones: Gaps and Opportunities towards Sustainable Production

Authors: Rui Silva, Eduardo Coelho, Tatiana Q. Aguiar, Lucília Domingues

Source: Applied Sciences, Vol 11, Iss 18, p 8500 (2021)

Subject Terms: lactones, flavors, fragrances, microbial production, de novo biosynthesis, metabolic engineering, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3417/11/18/8500; https://doaj.org/toc/2076-3417

Access URL: https://doaj.org/article/52776664a13e4bcd95319cd903a78545

Amino Acid Metabolism in Apicomplexan Parasites

Authors: Aarti Krishnan, Dominique Soldati-Favre

Source: Metabolites, Vol 11, Iss 2, p 61 (2021)

Subject Terms: amino acids, apicomplexans, Toxoplasma gondii, Plasmodium spp., de novo biosynthesis, uptake, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-1989/11/2/61; https://doaj.org/toc/2218-1989

Access URL: https://doaj.org/article/a269efd1a423418a9948da675e13b1a8

Fatty Acid Biosynthesis in Chromerids

Authors: Aleš Tomčala, Jan Michálek, Ivana Schneedorferová, Zoltán Füssy, Ansgar Gruber, Marie Vancová, Miroslav Oborník

Source: Biomolecules, Vol 10, Iss 8, p 1102 (2020)

Subject Terms: Chromera velia, Vitrella brassicaformis, fatty acids, de novo biosynthesis, evolution, elongation, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/10/8/1102; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/452d4489c99f4f318103cc850c7a87c3