SS-31 treatment ameliorates cardiac mitochondrial morphology and defective mitophagy in a murine model of Barth syndrome.

Authors: Russo, Silvia¹ (AUTHOR), De Rasmo, Domenico² (AUTHOR), Rossi, Roberta³ (AUTHOR), Signorile, Anna¹ (AUTHOR) anna.signorile@uniba.it, Lobasso, Simona¹ (AUTHOR) simona.lobasso@uniba.it

Source: Scientific Reports. 6/13/2024, Vol. 14 Issue 1, p1-12. 12p.

Ovarian Cancer: A Landscape of Mitochondria with Emphasis on Mitochondrial Dynamics.

Authors: De Rasmo, Domenico¹ (AUTHOR), Cormio, Antonella² (AUTHOR), Cormio, Gennaro^3,4 (AUTHOR), Signorile, Anna⁵ (AUTHOR) anna.signorile@uniba.it

Source: International Journal of Molecular Sciences. Jan2023, Vol. 24 Issue 2, p1224. 17p.

Subject Terms: *OVARIAN cancer, *MITOCHONDRIA, *MITOCHONDRIAL proteins, *OXIDATIVE phosphorylation, WESTERN countries

Pharmacological inhibition of the CB1 cannabinoid receptor restores abnormal brain mitochondrial CB1 receptor expression and rescues bioenergetic and cognitive defects in a female mouse model of Rett syndrome.

Authors: Cosentino, Livia, Urbinati, Chiara, Lanzillotta, Chiara, De Rasmo, Domenico, Valenti, Daniela, Pellas, Mattia, Quattrini, Maria Cristina, Piscitelli, Fabiana, Kostrzewa, Magdalena, Di Domenico, Fabio, Pietraforte, Donatella, Bisogno, Tiziana, Signorile, Anna, Vacca, Rosa Anna, De Filippis, Bianca

Source: Molecular Autism; 9/19/2024, Vol. 15 Issue 1, p1-14, 14p

Subject Terms: RETT syndrome, CANNABINOID receptors, BIOENERGETICS, MITOCHONDRIAL membranes, COGNITION disorders, MITOCHONDRIAL pathology

Beneficial effects of SS-31 peptide on cardiac mitochondrial dysfunction in tafazzin knockdown mice.

Authors: Russo, Silvia¹ (AUTHOR), De Rasmo, Domenico² (AUTHOR), Signorile, Anna¹ (AUTHOR), Corcelli, Angela¹ (AUTHOR), Lobasso, Simona¹ (AUTHOR) simona.lobasso@uniba.it

Source: Scientific Reports. 11/18/2022, Vol. 12 Issue 1, p1-14. 14p.

Subject Terms: *PEPTIDES, *MICE, *GENETIC disorders, *PHOSPHOLIPIDS, *THERAPEUTICS, *CARDIOLIPIN, *PLANT mitochondria

Mitochondria as pharmacological targets in Down syndrome

Authors: Valenti, Daniela, Braidy, Nady, De Rasmo, Domenico, Signorile, Anna, Rossi, Leonardo, Atanasov, A.G., Volpicella, Mariateresa, Henrion-Caude, Alexandra, Nabavi, S.M., Vacca, R.A.

Source: In Free Radical Biology and Medicine January 2018 114:69-83

Inhibition of Drp1-mediated mitochondrial fission improves mitochondrial dynamics and bioenergetics stimulating neurogenesis in hippocampal progenitor cells from a Down syndrome mouse model

Authors: Valenti, Daniela, Rossi, Leonardo, Marzulli, Domenico, Bellomo, Francesco, De Rasmo, Domenico, Signorile, Anna, Vacca, Rosa Anna

Source: In BBA - Molecular Basis of Disease December 2017 1863(12):3117-3127

Mitochondrial cAMP prevents apoptosis modulating Sirt3 protein level and OPA1 processing in cardiac myoblast cells

Authors: Signorile, Anna, Santeramo, Arcangela, Tamma, Grazia, Pellegrino, Tommaso, D'Oria, Susanna, Lattanzio, Paolo, De Rasmo, Domenico

Source: In BBA - Molecular Cell Research February 2017 1864(2):355-366

Impact of atypical mitochondrial cyclic-AMP level in nephropathic cystinosis

Authors: Bellomo, Francesco, Signorile, Anna, Tamma, Grazia, Ranieri, Marianna, Emma, Francesco, De Rasmo, Domenico

Source: Cellular and molecular life sciences. 75(18):3411-3422

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125358778.0x000001&indx=1&recIds=ETOCvdc_100125358778.0x000001

Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy

Authors: Celestini, Valentina, Tezil, Tugsan, Russo, Luciana, Fasano, Candida, Sanese, Paola, Forte, Giovanna, Peserico, Alessia, Lepore Signorile, Martina, Longo, Giovanna, De Rasmo, Domenico, Signorile, Anna, Gadaleta, Raffaella, Scialpi, Natasha, Terao, Mineko, Garattini, Enrico, Cocco, Tiziana, Villani, Gaetano, Moschetta, Antonio, Grossi, Valentina, Simone, Cristiano

Source: Cell death and disease. 9(2):1-20

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112267779.0x000001&indx=1&recIds=ETOCvdc_100112267779.0x000001

The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model

Authors: Valenti, Daniela, de Bari, Lidia, de Rasmo, Domenico, Signorile, Anna, Henrion-Caude, Alexandra, Contestabile, Andrea, Vacca, Rosa Anna

Source: In BBA - Molecular Basis of Disease June 2016 1862(6):1093-1104

cAMP regulates the functional activity, coupling efficiency and structural organization of mammalian FOF1 ATP synthase

Authors: De Rasmo, Domenico, Micelli, Loris, Santeramo, Arcangela, Signorile, Anna, Lattanzio, Paolo, Papa, Sergio

Source: In BBA - Bioenergetics April 2016 1857(4):350-358

High OXPHOS efficiency in RA-FUdr-differentiated SH-SY5Y cells: involvement of cAMP signalling and respiratory supercomplexes.

Authors: Matrella, Maria Laura, Valletti, Alessio, Gigante, Isabella, De Rasmo, Domenico, Signorile, Anna, Russo, Silvia, Lobasso, Simona, Lobraico, Donatella, Dibattista, Michele, Pacelli, Consiglia, Cocco, Tiziana

Source: Scientific Reports; 3/28/2024, Vol. 14 Issue 1, p1-18, 18p

Subject Terms: CYCLIC adenylic acid, NEURONAL differentiation, CELL differentiation, UNSATURATED fatty acids, CELL populations

Impaired enzymatic defensive activity, mitochondrial dysfunction and proteasome activation are involved in RTT cell oxidative damage

Authors: Cervellati, Carlo, Sticozzi, Claudia, Romani, Arianna, Belmonte, Giuseppe, De Rasmo, Domenico, Signorile, Anna, Cervellati, Franco, Milanese, Chiara, Mastroberardino, Pier Giorgio, Pecorelli, Alessandra, Savelli, Vinno, Forman, Henry J., Hayek, Joussef, Valacchi, Giuseppe

Source: In BBA - Molecular Basis of Disease October 2015 1852(10) Part A:2066-2074

Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: protective effect of CNF1

Authors: De Filippis, Bianca, Valenti, Daniela, de Bari, Lidia, De Rasmo, Domenico, Musto, Mattia, Fabbri, Alessia, Ricceri, Laura, Fiorentini, Carla, Laviola, Giovanni, Vacca, Rosa Anna

Source: In Free Radical Biology and Medicine June 2015 83:167-177

Intramitochondrial adenylyl cyclase controls the turnover of nuclear-encoded subunits and activity of mammalian complex I of the respiratory chain

Authors: De Rasmo, Domenico, Signorile, Anna, Santeramo, Arcangela, Larizza, Maria, Lattanzio, Paolo, Capitanio, Giuseppe, Papa, Sergio

Source: In BBA - Molecular Cell Research January 2015 1853(1):183-191

Regulation of the biogenesis of OXPHOS complexes in cell transition from replicating to quiescent state: Involvement of PKA and effect of hydroxytyrosol

Authors: Signorile, Anna, Micelli, Loris, De Rasmo, Domenico, Santeramo, Arcangela, Papa, Francesco, Ficarella, Romina, Gattoni, Giuliano, Scacco, Salvatore, Papa, Sergio

Source: In BBA - Molecular Cell Research April 2014 1843(4):675-684

Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome

Authors: Valenti, Daniela, De Rasmo, Domenico, Signorile, Anna, Rossi, Leonardo, de Bari, Lidia, Scala, Iris, Granese, Barbara, Papa, Sergio, Vacca, Rosa Anna

Source: In BBA - Molecular Basis of Disease April 2013 1832(4):542-552

Complex I deficiencies in neurological disorders

Authors: Papa, Sergio, De Rasmo, Domenico

Source: In Trends in Molecular Medicine January 2013 19(1):61-69

Activation of the cAMP cascade in human fibroblast cultures rescues the activity of oxidatively damaged complex I

Authors: De Rasmo, Domenico, Signorile, Anna, Larizza, Maria, Pacelli, Consiglia, Cocco, Tiziana, Papa, Sergio

Source: In Free Radical Biology and Medicine 15 February 2012 52(4):757-764

Rat Embryo Exposure to All-Trans Retinoic Acid Results in Postnatal Oxidative Damage of Respiratory Complex I in the Cerebellum

Authors: Signorile, Anna, Sardaro, Nicola, De Rasmo, Domenico, Scacco, Salvatore, Papa, Francesco, Borracci, Pietro, Carratù, Maria Rosaria, Papa, Sergio ^*

Source: In Molecular Pharmacology October 2011 80(4):704-713