Caplacizumab use in immune-mediated thrombotic thrombocytopenic purpura: an international multicentre retrospective Cohort study (The Capla 1000+ project)

Authors: Coppo, Paul ^{a, b, ∗}, Bubenheim, Michael ^c, Benhamou, Ygal ^{a, d, e}, Völker, Linus ^{f, g}, Brinkkötter, Paul ^{f, g}, Kühne, Lucas ^{f, g}, Knöbl, Paul ^h, Mingot-Castellano, Maria Eva ⁱ, Pascual-Izquierdo, Cristina ^j, de la Rubia, Javier ^k, del Rio Garma, Julio ^l, Chaturvedi, Shruti ^m, Masias, Camila ⁿ, Mazepa, Marshall ^o, Zheng, X. Long ^p, Sinkovits, György ^q, Réti, Marienn ^r, Patriquin, Christopher J. ^s, Pavenski, Katerina ^t, Boechat, Tiago ^u, Farias, João ^v, Oliveira Ribeiro, Eduardo Flavio ^w, Lobo de Andrade, Michaela Larissa ^w, Veyradier, Agnès ^{b, x}, Joly, Bérangère ^{b, x}, Bouzid, Raïda ^{a, b}, Sakai, Kazuya ^y, Matsumoto, Masanori ^y, Agosti, Pasquale ^{z, aa}, Mancini, Ilaria ^aa, Peyvandi, Flora ^{z, aa}, Gavriilaki, Eleni ^ab, Stubbs, Matthew ^ac, Hmaid, Amjad ^ac, Cataland, Spero ^ad, Lämmle, Bernhard ^{ae, af}, Scully, Marie ^ac

Source: In eClinicalMedicine April 2025 82

Is t(11;14) Always a Standard-Risk Cytogenetic Abnormality? Results From GEM05MENOS65 and GEM2012 PETHEMA/GEM Transplantation Trials

Authors: Moreno, David F. ¹, Oriol, Albert ², de la Rubia, Javier ³, Hernández, Miguel T. ⁴, Iñigo, María Belén ⁵, Palomera, Luis ⁶, de Arriba, Felipe ⁷, González, Yolanda ⁸, Teruel, Ana Isabel ⁹, Pardo, Jordi López ¹⁰, López de la Guía, Ana ¹¹, Sampol, Antonia ¹², Ríos-Tamayo, Rafael ¹³, Sureda, Anna ¹⁴, Gutiérrez, Norma C. ¹⁵, Calasanz, Maria-Jose ¹⁶, Ramos, María Luisa Martín ¹⁷, Mateos, María Victoria ¹⁵, San Miguel, Jesús ¹⁶, Lahuerta, Juan José ¹⁷, Bladé, Joan ¹, Rosiñol, Laura ^{1, ⁎}

Source: In Clinical Lymphoma, Myeloma and Leukemia January 2025

Single-Unit Transfusion Policy in Autologous Hematopoietic Stem Cell Transplantation: Less is Not Worse

Authors: Marco-Ayala, Javier, Asensi Cantó, Pedro, Suarez, Marina, Lamas, Brais, Santiago, Marta, Gómez, Inés, Arnao, Mario, Sanz, Jaime, Montava, Alberto, Sanz, Miguel Ángel, de la Rubia, Javier, Solves, Pilar

Source: In Transfusion Medicine Reviews October 2024 38(4)

Caplacizumab improves clinical outcomes and is well tolerated across clinically relevant subgroups of patients with immune-mediated thrombotic thrombocytopenic purpura

Authors: Pavenski, Katerina, Scully, Marie, Coppo, Paul, Cataland, Spero, Knöbl, Paul, Peyvandi, Flora, Kremer Hovinga, Johanna A., de la Rubia, Javier, Khan, Umer, Marques, Ana Paula, Gunawardena, Sriya

Source: In Research and Practice in Thrombosis and Haemostasis July 2024 8(5)

Gastric Bleeding in Stem Cell Transplantation: A Focus on Gastric Vascular Ectasia Under Post-Transplant Cyclophosphamide, Sirolimus, and Mycophenolate Mofetil Prophylaxis

Authors: Eirís, Juan ¹, Montoro, Juan ^{1, 2, 3}, Villalba, Marta ^{1, 2}, Chorão, Pedro ^{1, 2}, Pérez-Bravo, Marina ⁴, Rausell, Nuria ¹, Satorres, Carla ¹, Asensi Cantó, Pedro ¹, Gómez-Seguí, Inés ¹, Solves, Pilar ¹, Santiago, Marta ¹, Lloret-Madrid, Pilar ^{1, 2}, Granados, Pablo ¹, Martínez-Campuzano, David ¹, Benavente, Rafael ⁵, Louro, Alberto ^{1, 2}, Rebollar, Paula ^{1, 2}, Perla, Aurora ^{1, 2}, Sanz, Miguel A. ^{1, 2, 5}, de la Rubia, Javier ^{1, 2, 3, 6}, Balaguer-Roselló, Aitana ^{1, 2, 7, #, ⁎}, Sanz, Jaime ^{1, 2, 6, 7, #}

Source: In Transplantation and Cellular Therapy January 2025 31(1):24-24

Geriatric assessment in hematology scale predicts treatment tolerability in older patients diagnosed with hematological malignancies: The RETROGAH study

Authors: de la Rubia, Javier, González, Bernardo, Cruz-Jentoft, Alfonso J., Iglesias, Lorena, Jarque, Isidro, Persona, Ernesto Pérez, Lluch, Rafael, Marrero, Carmen, Zudaire, Maite, Gironella, Mercedes, Hernández-Rivas, José Ángel, Arnan, Montserrat, Olivier, Carmen, Encinas, Cristina, Soler, Juan Alfonso, Payer, Ángel Ramírez, Casado, Alfonso, Fernández, Patricia, Vilanova, David, Bonanad, Santiago

Source: In Journal of Geriatric Oncology January 2023 14(1)

Real-world effectiveness of caplacizumab vs the standard of care in immune thrombotic thrombocytopenic purpura

Authors: Izquierdo, Cristina Pascual, Mingot-Castellano, María Eva ^∗, Fuentes, Ana E. Kerguelen, García-Arroba Peinado, José, Cid, Joan, Jimenez, Maria Moraima, Valcarcel, David, Gómez-Seguí, Inés, de la Rubia, Javier, Martin, Paz, Goterris, Rosa, Hernández, Luis, Tallón, Inmaculada, Varea, Sara, Fernández, Marta, García-Muñoz, Nadia, Vara, Míriam, Zarzoso, Miguel Fernández, García-Candel, Faustino, Paciello, María Liz, García-García, Irene, Zalba, Saioa, Campuzano, Verónica, Gala, José María, Estévez, Julia Vidán, Jiménez, Gemma Moreno, López Lorenzo, José Luis, Arias, Elena González, Freiría, Carmen, Solé, María, Ávila Idrovo, Laura Francisca, Hernández Castellet, José Carlos, Cruz, Naylen, Lavilla, Esperanza, Pérez-Montaña, Albert, Atucha, Jon Ander, Moreno Beltrán, María Esperanza, Moreno Macías, Juán Ramón, Salinas, Ramón, del Rio-Garma, Julio

Source: In Blood Advances 27 December 2022 6(24):6219-6227

Long‐term follow‐up of patients treated with caplacizumab and safety and efficacy of repeat caplacizumab use: Post‐HERCULES study

Authors: Scully, Marie ^*, de la Rubia, Javier, Pavenski, Katerina, Metjian, Ara, Knöbl, Paul, Peyvandi, Flora, Cataland, Spero, Coppo, Paul, Kremer Hovinga, Johanna A., Minkue Mi Edou, Jessica, De Passos Sousa, Rui, Callewaert, Filip, Gunawardena, Sriya, Lin, Julie

Source: In Journal of Thrombosis and Haemostasis December 2022 20(12):2810-2822

High‐risk features of early relapse in newly‐diagnosed multiple myeloma: The impact of cytogenetics and response to initial therapy.

Authors: Manubens, Andrea, Paiva, Bruno, Gutiérrez, Norma C., Fernandez, Manuela, Calasanz, Maria‐José, Rosiñol, Laura, Oriol, Albert, Blanchard, Ma Jesús, Carrillo, Estrella, Benavente, Celina, Martínez‐López, Joaquín, Bargay, Joan, Hernández, Miguel Teodoro, de la Rubia, Javier, González, Yolanda, Paricio, Miguel, de Arriba, Felipe, Ocio, Enrique M., Teruel, Ana Isabel, de la Guia, Ana López

Source: HemaSphere; Apr2025, Vol. 9 Issue 4, p1-10, 10p

Subject Terms: MULTIPLE myeloma, INVESTIGATIONAL therapies, PREDICTIVE validity, TRANSPLANTATION of organs, tissues, etc., CALCIUM

Synchronization of fluctuating delay-coupled chaotic networks

Authors: Martin, Manuel Jimenez, Rodríguez-Laguna, Javier, D'Huys, Otti, de la Rubia, Javier, Korutcheva, Elka

Source: Phys. Rev. E 95, 052210 (2017)

Subject Terms: Nonlinear Sciences - Chaotic Dynamics, Condensed Matter - Disordered Systems and Neural Networks, Condensed Matter - Statistical Mechanics

Access URL: http://arxiv.org/abs/1610.06507

Cytomegalovirus Reactivations in Allogeneic Hematopoietic Stem Cell Transplantation from HLA-Matched and Haploidentical Donors with Post-Transplantation Cyclophosphamide

Authors: Chorão, Pedro, Henriques, Marta, Villalba, Marta, Montoro, Juan, Balaguer-Roselló, Aitana, González, Eva María, Gómez, María Dolores, Gómez, Inés, Solves, Pilar, Santiago, Marta, Asensi, Pedro, Lamas, Brais, Bataller, Ana, Granados, Pablo, Eiris, Juan, Martínez, David, Louro, Alberto, Rebollar, Paula, Perla, Aurora, Salavert, Miguel, de la Rubia, Javier, Sanz, Miguel Ángel, Sanz, Jaime

Source: In Transplantation and Cellular Therapy May 2024 30(5):538-538

Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): a multicentre, open-label, randomised phase 3 trial

Authors: Moreau, Philippe, Dimopoulos, Meletios-Athanasios, Mikhael, Joseph, Yong, Kwee, Capra, Marcelo, Facon, Thierry, Hajek, Roman, Spicka, Ivan, Baker, Ross, Kihyun, Kim, Martinez, Gracia, Chang-Ki, Min, Pour, Ludek, Leleu, Xavier, Oriol, Albert, Youngil, Koh, Suzuki, Kenshi, Martin, Tom, Quach, Hang, Lim, Andrew, Crowther, Helen, Sia, Hanlon, Hulin, Cyrille, Mohty, Mohamad, Mikala, Gabor, Nagy, Zsolt, Reinoso Segura, Marta, Rosinol, Laura, Yagci, Munci, Turgut, Mehmet, Garg, Mamta, Parmar, Gurdeep, Augustson, Brad, Castro, Nelson, Crusoe, Edvan, Pika, Tomas, Delimpasi, Sosana, Ishizawa, Kenichi, George, Anup, Konstantinova, Tatiana, De La Rubia, Javier, Sung-Hyun, Kim, Maiolino, Angelo, Reiman, Anthony, LeBlanc, Richard, Ito, Shigeki, Tanaka, Junji, Luchinin, Alexander, Kryuchkova, Irina, Martinez, Joaquin, Shustik, Jesse, Karlin, Lionel, Symeonidis, Anargyros, Egyed, Miklos, Petrini, Mario, Cavo, Michele, Uchiyama, Michihiro, Blacklock, Hilary, Arat, Mutlu, Griffin, James, Hunter, Hannah, Buck, Tonda, Anagnostopoulos, Achilles, Konstantopoulos, Konstantinos, Masszi, Tamas, Bringhen, Sara, Gamberi, Barbara, Kawano, Yawara, Jin Seok, Kim, Ozdogu, Hakan, Ozkalemkas, Fahir, Špička, Ivan, Kim, Kihyun, Min, Chang-Ki, Koh, Youngil, Risse, Marie-Laure, Asset, Gaelle, Macé, Sandrine, Martin, Thomas ^*

Source: In The Lancet 19-25 June 2021 397(10292):2361-2371

A 3-states magnetic model of binary decisions in sociophysics

Authors: Fernandez, Miguel A., Korutcheva, Elka, de la Rubia, Javier

Source: Physica A 462 (2016) 603-618

Subject Terms: Physics - Physics and Society, Condensed Matter - Statistical Mechanics, 82B44

Access URL: http://arxiv.org/abs/1507.05111

Caplacizumab prevents refractoriness and mortality in acquired thrombotic thrombocytopenic purpura: integrated analysis

Authors: Peyvandi, Flora, Cataland, Spero, Scully, Marie, Coppo, Paul, Knoebl, Paul, Kremer Hovinga, Johanna A., Metjian, Ara, de la Rubia, Javier, Pavenski, Katerina, Minkue Mi Edou, Jessica, De Winter, Hilde, Callewaert, Filip ^*

Source: In Blood Advances 27 April 2021 5(8):2137-2141

Treatment of multiple myeloma-related bone disease: recommendations from the Bone Working Group of the International Myeloma Working Group

Authors: Terpos, Evangelos ^*, Zamagni, Elena, Lentzsch, Suzanne, Drake, Matthew T, García-Sanz, Ramón, Abildgaard, Niels, Ntanasis-Stathopoulos, Ioannis, Schjesvold, Fredrik, de la Rubia, Javier, Kyriakou, Charalampia, Hillengass, Jens, Zweegman, Sonja, Cavo, Michele, Moreau, Philippe, San-Miguel, Jesus, Dimopoulos, Meletios A, Munshi, Nikhil, Durie, Brian G M, Raje, Noopur

Source: In The Lancet Oncology March 2021 22(3):e119-e130

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard- and high-risk myeloma

Authors: Goicoechea, Ibai, Puig, Noemi, Cedena, Maria-Teresa, Burgos, Leire, Cordón, Lourdes, Vidriales, María-Belén, Flores-Montero, Juan, Gutierrez, Norma C., Calasanz, Maria-Jose, Ramos, Maria-Luisa Martin, Lara-Astiaso, David, Vilas-Zornoza, Amaia, Alignani, Diego, Rodriguez, Idoia, Sarvide, Sarai, Alameda, Daniel, Garcés, Juan José, Rodriguez, Sara, Fresquet, Vicente, Celay, Jon, Garcia-Sanz, Ramón, Martinez-Lopez, Joaquin, Oriol, Albert, Rios, Rafael, Martin-Sanchez, Jesus, Martinez-Martinez, Rafael, Sarra, Josep, Hernandez, Miguel-Teodoro, de la Rubia, Javier, Krsnik, Isabel, Moraleda, Jose-Maria, Palomera, Luis, Bargay, Joan, Martinez-Climent, Jose-Angel, Orfao, Alberto, Rosiñol, Laura, Mateos, Maria-Victoria, Lahuerta, Juan-José, Blade, Joan, San Miguel, Jesús, Paiva, Bruno ^*

Source: In Blood 7 January 2021 137(1):49-60

High‐risk cytogenetic abnormalities in multiple myeloma: PETHEMA‐GEM experience.

Authors: González‐Calle, Veronica, Rodriguez‐Otero, Paula, Calasanz, Maria J., Guijarro, Manuela, Martínez‐López, Joaquin, Rosiñol, Laura, Hernández, Miguel T., Teruel, Ana I., Gironella, Mercedes, Oriol, Albert, de la Rubia, Javier, González‐Rodríguez, Ana P., Bargay, Joan, de Arriba, Felipe, Palomera, Luis, González‐Pérez, Marta‐Sonia, Sureda, Anna, Ocio, Enrique, Lahuerta, Juan J., Bladé, Joan

Source: HemaSphere; Dec2024, Vol. 8 Issue 12, p1-11, 11p

Venetoclax or placebo in combination with bortezomib and dexamethasone in patients with relapsed or refractory multiple myeloma (BELLINI): a randomised, double-blind, multicentre, phase 3 trial

Authors: Kumar, Shaji K ^*, Harrison, Simon J, Cavo, Michele, de la Rubia, Javier, Popat, Rakesh, Gasparetto, Cristina, Hungria, Vania, Salwender, Hans, Suzuki, Kenshi, Kim, Inho, Punnoose, Elizabeth A, Hong, Wan-Jen, Freise, Kevin J, Yang, Xiaoqing, Sood, Anjla, Jalaluddin, Muhammad, Ross, Jeremy A, Ward, James E, Maciag, Paulo C, Moreau, Philippe

Source: In The Lancet Oncology December 2020 21(12):1630-1642

Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma

Authors: Perez, Cristina ^{1, *}, Botta, Cirino ^{1, 2, *}, Zabaleta, Aintzane ¹, Puig, Noemi ³, Cedena, Maria-Teresa ⁴, Goicoechea, Ibai ¹, Alameda, Daniel ¹, San José-Eneriz, Edurne ¹, Merino, Juana ¹, Rodríguez-Otero, Paula ¹, Maia, Catarina ¹, Alignani, Diego ¹, Maiso, Patricia ¹, Manrique, Irene ¹, Lara-Astiaso, David ¹, Vilas-Zornoza, Amaia ¹, Sarvide, Sarai ¹, Riillo, Caterina ⁵, Rossi, Marco ⁵, Rosiñol, Laura ⁶, Oriol, Albert ⁷, Blanchard, María-Jesús ⁸, Rios, Rafael ⁹, Sureda, Anna ¹⁰, Martin, Jesus ¹¹, Martinez, Rafael ¹², Bargay, Joan ¹³, de la Rubia, Javier ^{14, 15}, Hernandez, Miguel-Teodoro ¹⁶, Martinez-Lopez, Joaquin ⁴, Orfao, Alberto ^{3, 17, 18, 19}, Agirre, Xabier ¹, Prosper, Felipe ¹, Mateos, Maria-Victoria ³, Lahuerta, Juan-José ⁴, Blade, Joan ⁶, San-Miguel, Jesús F. ¹, Paiva, Bruno ^{1, 1}

Source: In Blood 9 July 2020 136(2):199-209

Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma: Results of the Compassionate Use or the Expanded Access Program in Spain.

Authors: de la Rubia, Javier^1,2 (AUTHOR) delarubia_jav@gva.es, Alonso, Rafael³ (AUTHOR), Clavero, María Esther⁴ (AUTHOR), Askari, Elham⁵ (AUTHOR), García, Alfonso⁶ (AUTHOR), Antón, Cristina⁷ (AUTHOR), Fernández, Margarita⁸ (AUTHOR), Escalante, Fernando⁹ (AUTHOR), García, Ana¹⁰ (AUTHOR), Rios-Tamayo, Rafael¹¹ (AUTHOR), Conesa, Venancio¹² (AUTHOR), Bermúdez, María Arancha¹³ (AUTHOR), Merchán, Beatriz¹⁴ (AUTHOR), Velasco, Alberto E.¹⁵ (AUTHOR), Blanchard, María Jesús¹⁶ (AUTHOR), Sampol, Antonia¹⁷ (AUTHOR), Gainza, Eukene¹⁸ (AUTHOR), Hernández, Prisma Montserrat¹⁹ (AUTHOR), Alegre, Adrián²⁰ (AUTHOR)

Source: Cancers. Jun2023, Vol. 15 Issue 11, p2964. 13p.

Subject Terms: *THERAPEUTIC use of immunoglobulins, *RESEARCH, *SCIENTIFIC observation, *CONFIDENCE intervals, *IMMUNOGLOBULINS, *OPTIC nerve diseases, *CANCER relapse, *INVESTIGATIONAL drugs, *CELL receptors, *RETROSPECTIVE studies, *ACQUISITION of data, *TREATMENT effectiveness, *COMPARATIVE studies, *MEDICAL records, *DESCRIPTIVE statistics, *MULTIPLE myeloma, *PROGRESSION-free survival, *PATIENT safety, *OVERALL survival, *DISEASE risk factors

Geographic Terms: SPAIN