Accelerated Cortical Thinning in Schizophrenia Is Associated With Rare and Common Predisposing Variation to Schizophrenia and Neurodevelopmental Disorders

Authors: González-Peñas, Javier, Díaz-Caneja, Covadonga M., Costas, Javier, Gurriarán, Xaquín, Andreu-Bernabeu, Álvaro, Fañanas, Lourdes, Rosa de la Cruz, Araceli, Arias, Bárbara, Bobes, Julio, Pinto, Ana González, Crespo-Facorro, B., Martorell, L., Vilella, Elisabet, Muntané, Gerard, Moltó, María Dolores, Escartí, María José, Rivero, Olga, Parellada, Mara, Moreno, Carmen, Arango, Celso, Alloza, Clara, Brouwer, Rachel, González-Lois, Noemí, Gallego, Ana Guil, de Hoyos, Lucía, Romero-García, Rafael, Fañanás, Lourdes, González-Pinto, Ana, Crespo-Facorro, Benedicto, Martorell, Lourdes, Arrojo, Manuel, Gutiérrez-Zotes, Alfonso, Perez-Rando, Marta, Buimer, Elizabeth, van Haren, Neeltje, Cahn, Wiepke, O’Donovan, Michael, Kahn, René S., Pol, Hilleke Hulshoff, Janssen, Joost, Schnack, Hugo

Source: In Biological Psychiatry 1 September 2024 96(5):376-389

Genome-Wide Analyses of Vocabulary Size in Infancy and Toddlerhood: Associations With Attention-Deficit/Hyperactivity Disorder, Literacy, and Cognition-Related Traits

Authors: Andreassen, Ole A., Bartels, Meike, Boomsma, Dorret, Dale, Philip S., Ehli, Erik, Fernandez-Orth, Dietmar, Guxens, Mònica, Hakulinen, Christian, Harris, Kathleen Mullan, Haworth, Simon, de Hoyos, Lucía, Jaddoe, Vincent, Keltikangas-Järvinen, Liisa, Lehtimäki, Terho, Middeldorp, Christel, Min, Josine L., Mishra, Pashupati P., Njølstad, Pål Rasmus, Sunyer, Jordi, Tate, Ashley E., Timpson, Nicholas, van der Laan, Camiel, Vrijheid, Martine, Vuoksimaa, Eero, Whipp, Alyce, Ystrom, Eivind, ACTION Consortium, Barwon Infant Study investigator group, Verhoef, Ellen, Allegrini, Andrea G., Jansen, Philip R., Lange, Katherine, Wang, Carol A., Morgan, Angela T., Ahluwalia, Tarunveer S., Symeonides, Christos, Eising, Else, Franken, Marie-Christine, Hypponen, Elina, Mansell, Toby, Olislagers, Mitchell, Omerovic, Emina, Rimfeld, Kaili, Schlag, Fenja, Selzam, Saskia, Shapland, Chin Yang, Tiemeier, Henning, Whitehouse, Andrew J.O., Saffery, Richard, Bønnelykke, Klaus, Reilly, Sheena, Pennell, Craig E., Wake, Melissa, Cecil, Charlotte A.M., Plomin, Robert, Fisher, Simon E., St. Pourcain, Beate

Source: In Biological Psychiatry 1 May 2024 95(9):859-869

Recent natural selection conferred protection against schizophrenia by non-antagonistic pleiotropy.

Authors: González-Peñas, Javier^1,2,3 (AUTHOR) javier.gonzalez@iisgm.com, de Hoyos, Lucía^1,2,4 (AUTHOR), Díaz-Caneja, Covadonga M.^1,2,3,5 (AUTHOR), Andreu-Bernabeu, Álvaro^1,2,5 (AUTHOR), Stella, Carol^1,2 (AUTHOR), Gurriarán, Xaquín^1,2 (AUTHOR), Fañanás, Lourdes^3,6 (AUTHOR), Bobes, Julio^3,7 (AUTHOR), González-Pinto, Ana^3,8 (AUTHOR), Crespo-Facorro, Benedicto^3,9 (AUTHOR), Martorell, Lourdes^3,10 (AUTHOR), Vilella, Elisabet^3,10 (AUTHOR), Muntané, Gerard^3,10 (AUTHOR), Molto, María Dolores^3,11,12 (AUTHOR), Gonzalez-Piqueras, Jose Carlos^3,12,13 (AUTHOR), Parellada, Mara^1,2,3,5 (AUTHOR), Arango, Celso^1,2,3,5 (AUTHOR), Costas, Javier¹⁴ (AUTHOR)

Source: Scientific Reports. 11/20/2023, Vol. 13 Issue 1, p1-15. 15p.

Subject Terms: *NATURAL selection, *SCHIZOPHRENIA, *LIFE expectancy, *ENVIRONMENTAL history, *HUMAN evolution, *MENTAL illness, *HERITABILITY

Geographic Terms: AFRICA

Dissimilarity in Sulcal Width Patterns in the Cortex can be Used to Identify Patients With Schizophrenia With Extreme Deficits in Cognitive Performance

Authors: Janssen, Joost, Díaz-Caneja, Covadonga M, Alloza, Clara, Schippers, Anouck, de Hoyos, Lucía, Santonja, Javier, Gordaliza, Pedro M, Buimer, Elizabeth E L, van Haren, Neeltje E M, Cahn, Wiepke, Arango, Celso, Kahn, René S, Hulshoff Pol, Hilleke E, Schnack, Hugo G

Source: Schizophrenia bulletin. 47(2):552-561

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132704973.0x000001&indx=1&recIds=ETOCvdc_100132704973.0x000001

Sex Differences in Lifespan Trajectories and Variability of Human Sulcal and Gyral Morphology

Authors: Díaz-Caneja, Covadonga M, Alloza, Clara, Gordaliza, Pedro M, Fernández-Pena, Alberto, de Hoyos, Lucía, Santonja, Javier, Buimer, Elizabeth E L, van Haren, Neeltje E M, Cahn, Wiepke, Arango, Celso, Kahn, René S, Hulshoff Pol, Hilleke E, Schnack, Hugo G, Janssen, Joost

Source: Cerebral cortex. 31(11):5107-5120

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131725074.0x000001&indx=1&recIds=ETOCvdc_100131725074.0x000001

Structural models of genome-wide covariance identify multiple common dimensions in autism.

Authors: de Hoyos, Lucía, Barendse, Maria T., Schlag, Fenja, van Donkelaar, Marjolein M. J., Verhoef, Ellen, Shapland, Chin Yang, Klassmann, Alexander, Buitelaar, Jan, Verhulst, Brad, Fisher, Simon E., Rai, Dheeraj, St Pourcain, Beate

Source: Nature Communications; 2/27/2024, Vol. 15 Issue 1, p1-15, 15p

Subject Terms: STRUCTURAL models, AUTISM spectrum disorders, AUTISM, DEVELOPMENTAL delay, STRUCTURAL equation modeling, PHENOTYPES, GENOMES

74. STRUCTURAL EQUATION MODELLING IN THE GENOMICS ERA: STATE-OF-THE-ART AND FUTURE DEVELOPMENTS

Authors: Barendse, Mariska, Klassmann, Alexander, de Hoyos, Lucía, Rai, Dheeraj, Fisher, Simon, Pourcain, Beate St

Source: European neuropsychopharmacology. 51:e80-e81

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141349002.0x000001&indx=1&recIds=ETOCvdc_100141349002.0x000001

W14. GENETIC CLUSTERING OF CO-OCCURRING SYMPTOMS IN PEOPLE WITH AUTISM: A MULTIVARIATE GENETIC VARIANCE ANALYSIS OF GENETIC RELATIONSHIP MATRICES IN THE SPARK SAMPLE

Authors: de Hoyos, Lucía, Barendse, Maria T., van Donkelaar, Marjolein M.J., Verhoef, Ellen, Fisher, Simon E., Rai, Dheeraj, Pourcain, Beate St

Source: European neuropsychopharmacology. 51:e154-e155

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141346871.0x000001&indx=1&recIds=ETOCvdc_100141346871.0x000001

T10. STRUCTURAL MODELS OF GENOME-WIDE COVARIANCE IDENTIFY MULTIPLE GENETIC INFLUENCES ACROSS ASD SYMPTOMS

Authors: de Hoyos, Lucía, Barendse, Maria T, Schlag, Fenja, van Donkelaar, Marjolein M J, Verhoef, Ellen, Shapland, Chin Yang, Buitelaar, Jan, Verhulst, Brad, Fisher, Simon E, Rai, Dheeraj, Pourcain, Beate St

Source: European neuropsychopharmacology. 63:e173-e173

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100170516743.0x000001&indx=1&recIds=ETOCvdc_100170516743.0x000001

Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia.

Authors: Andreu-Bernabeu, Álvaro, Díaz-Caneja, Covadonga M., Costas, Javier, De Hoyos, Lucía, Stella, Carol, Gurriarán, Xaquín, Alloza, Clara, Fañanás, Lourdes, Bobes, Julio, González-Pinto, Ana, Crespo-Facorro, Benedicto, Martorell, Lourdes, Vilella, Elisabet, Muntané, Gerard, Nacher, Juan, Molto, María Dolores, Aguilar, Eduardo Jesús, Parellada, Mara, Arango, Celso, González-Peñas, Javier

Source: Nature Communications; 10/23/2022, Vol. 13 Issue 1, p1-11, 11p

Subject Terms: SOCIAL isolation, SCHIZOPHRENIA, AUTISTIC children, ATTENTION-deficit hyperactivity disorder, LONELINESS, ALCOHOLISM

40. GENOME-WIDE ASSOCIATION META-ANALYSIS OF SOCIAL BEHAVIOUR DURING CHILDHOOD AND ADOLESCENCE

Authors: Schlag, Fenja, de Hoyos, Lucia, Admiraal, Danielle, Pourcain, Beate St

Source: In European Neuropsychopharmacology October 2023 75 Supplement 1:S77-S78

S84LONELINESS AND SCHIZOPHRENIA: COMMON VARIATION AND CAUSALITY

Authors: Andreu-Bernabeu, Alvaro, De Hoyos, Lucía, Costas, Javier, Diaz-Caneja, Covadonga M., Parellada, Mara, Arango, Celso, Gonzalez-Peñas, Javier

Source: European neuropsychopharmacology. 29(S5):S156-S157

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100091118087.0x000001&indx=1&recIds=ETOCvdc_100091118087.0x000001

T84COMMON PREDISPOSING VARIATION TO SCHIZOPHRENIA IS SUBJECTED TO RECENT NATURAL SELECTION BY DECREASING ALLELE FREQUENCY IN EUROPEAN POPULATIONS

Authors: Gonzalez-Peñas, Javier, Costas, Javier, De Hoyos, Lucía, González-Vioque, Emiliano, Parellada, Mara, Arango, Celso

Source: European neuropsychopharmacology. 29(S5):S260-S261

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100091117379.0x000001&indx=1&recIds=ETOCvdc_100091117379.0x000001