Formyl peptide receptor 1 signaling strength orchestrates the switch from pro-inflammatory to pro-resolving responses: The way to exert its anti-angiogenic and tumor suppressor functions

Authors: Liotti, Federica ^a, Marotta, Maria ^b, Costanzo, Mattia ^c, De Simone, Chiara ^c, Zirpoli, Sara ^a, De Falco, Valentina ^b, Melillo, Rosa Marina ^{a, 1, ⁎}, Prevete, Nella ^{c, 2, ⁎⁎}

Source: In Biomedicine & Pharmacotherapy May 2025 186

Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics

Authors: Anand, Uttpal, Dey, Abhijit, Chandel, Arvind K. Singh, Sanyal, Rupa, Mishra, Amarnath, Pandey, Devendra Kumar, De Falco, Valentina, Upadhyay, Arun, Kandimalla, Ramesh, Chaudhary, Anupama, Dhanjal, Jaspreet Kaur, Dewanjee, Saikat, Vallamkondu, Jayalakshmi, Pérez de la Lastra, José M.

Source: Genes & diseases. 10(4):1367-1401

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193392063.0x000001&indx=1&recIds=ETOCvdc_100193392063.0x000001

N‐Acetyl‐L‐Cysteine (NAC) Blunts Axitinib‐Related Adverse Effects in Preclinical Models of Glioblastoma.

Authors: Formato, Alessia, Salbini, Maria, Orecchini, Elisa, Pellegrini, Manuela, Buccarelli, Mariachiara, Vitiani, Lucia Ricci, Giannetti, Stefano, Pallini, Roberto, D'Alessandris, Quintino Giorgio, Lauretti, Liverana, Martini, Maurizio, De Falco, Valentina, Levi, Andrea, Falchetti, Maria Laura, Mongiardi, Maria Patrizia

Source: Cancer Medicine; Oct2024, Vol. 13 Issue 19, p1-12, 12p

Subject Terms: VASCULAR endothelial growth factor receptors, STEM cell treatment, ATAXIA telangiectasia, RENAL cell carcinoma, CELLULAR aging

Targeting the p90RSK/MDM2/p53 Pathway Is Effective in Blocking Tumors with Oncogenic Up-Regulation of the MAPK Pathway Such as Melanoma and Lung Cancer.

Authors: Maietta, Immacolata, Viscusi, Eleonora, Laudati, Stefano, Iannaci, Giuseppe, D'Antonio, Antonio, Melillo, Rosa Marina, Motti, Maria Letizia, De Falco, Valentina

Source: Cells (2073-4409); Sep2024, Vol. 13 Issue 18, p1546, 20p

Subject Terms: DRUG resistance in cancer cells, CELL cycle regulation, MEDULLARY thyroid carcinoma, INHIBITION of cellular proliferation, LUNG tumors

Corrigendum to ‘Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics’ [Genes & Diseases 10 (2023) 1367–1401]

Authors: Anand, Uttpal, Dey, Abhijit, Singh Chandel, Arvind K., Sanyal, Rupa, Mishra, Amarnath, Pandey, Devendra Kumar, De Falco, Valentina, Upadhyay, Arun, Kandimalla, Ramesh, Chaudhary, Anupama, Dhanjal, Jaspreet Kaur, Dewanjee, Saikat, Vallamkondu, Jayalakshmi, Pérez de la Lastra, José M.

Source: In Genes & Diseases July 2024 11(4)

The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer

Authors: De Falco, Valentina, Carlomagno, Francesca, Li, Hong-yu, Santoro, Massimo

Source: In Best Practice & Research Clinical Endocrinology & Metabolism June 2017 31(3):307-318

Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene

Authors: Mendes Oliveira, Duarte, Grillone, Katia, Mignogna, Chiara, De Falco, Valentina, Laudanna, Carmelo, Biamonte, Flavia, Locane, Rosa, Corcione, Francesco, Fabozzi, Massimiliano, Sacco, Rosario, Viglietto, Giuseppe, Malanga, Donatella, Rizzuto, Antonia

Source: Journal of experimental & clinical cancer research. 37(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164011276.0x000001&indx=1&recIds=ETOCvdc_100164011276.0x000001

Insights into the molecular function of the inactivating mutations of B-Raf involving the DFG motif

Authors: Moretti, Sonia, De Falco, Valentina, Tamburrino, Anna, Barbi, Flavia, Tavano, Maria, Avenia, Nicola, Santeusanio, Fausto, Santoro, Massimo, Macchiarulo, Antonio, Puxeddu, Efisio

Source: In BBA - Molecular Cell Research 2009 1793(11):1634-1645

p90RSK Regulates p53 Pathway by MDM2 Phosphorylation in Thyroid Tumors.

Authors: Maietta, Immacolata, Del Peschio, Francesca, Buonocore, Preziosa, Viscusi, Eleonora, Laudati, Stefano, Iannaci, Giuseppe, Minopoli, Michele, Motti, Maria Letizia, De Falco, Valentina

Source: Cancers; Jan2023, Vol. 15 Issue 1, p121, 22p

Subject Terms: ENZYME metabolism, IN vitro studies, IN vivo studies, THYROID gland tumors, IMMUNOHISTOCHEMISTRY, PROTEOLYTIC enzymes, APOPTOSIS, CELLULAR signal transduction, GENE expression, IMMUNOBLOTTING, IMMUNOASSAY, TUMOR suppressor genes, RESEARCH funding, CELL proliferation, MITOGEN-activated protein kinases, PHOSPHORYLATION

Correction to: Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene

Authors: Oliveira, Duarte Mendes, Grillone, Katia, Mignogna, Chiara, De Falco, Valentina, Laudanna, Carmelo, Biamonte, Flavia, Locane, Rosa, Corcione, Francesco, Fabozzi, Massimiliano, Sacco, Rosario, Viglietto, Giuseppe, Malanga, Donatella, Rizzuto, Antonia

Source: Journal of experimental & clinical cancer research. 37(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129332382.0x000001&indx=1&recIds=ETOCvdc_100129332382.0x000001

The Oncogenic Activity of RET Point Mutants for Follicular Thyroid Cells May Account for the Occurrence of Papillary Thyroid Carcinoma in Patients Affected by Familial Medullary Thyroid Carcinoma

Authors: Melillo, Rosa Marina, Cirafici, Anna Maria, De Falco, Valentina, Bellantoni, Marie, Chiappetta, Gennaro, Fusco, Alfredo, Carlomagno, Francesca, Picascia, Antonella, Tramontano, Donatella, Tallini, Giovanni, Santoro, Massimo

Source: In The American Journal of Pathology 2004 165(2):511-521

RAI(ShcC/N-Shc)-dependent recruitment of GAB1 to RET oncoproteins potentiates PI3-K signalling in thyroid tumors.

Authors: de Falco, Valentina¹, Guarino, Valentina¹, Malorni, Luca¹, Cirafici, Anna Maria¹, Troglio, Flavia², Erreni, Marco², Pelicci, Giuliana², Santoro, Massimo¹, Melillo, Rosa Marina¹ rosmelil@unina.it

Source: Oncogene. 9/15/2005, Vol. 24 Issue 41, p6303-6313. 11p. 6 Diagrams.

Subject Terms: *THYROID gland tumors, *TUMORS, *ONCOGENES, *PROTEINS, *PROTEOMICS, *MYC proteins, *TRANSCRIPTION factors, *TUMOR proteins

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