GTAC enables parallel genotyping of multiple genomic loci with chromatin accessibility profiling in single cells

Authors: Turkalj, Sven, Jakobsen, Niels Asger, Groom, Angus, Metzner, Marlen, Riva, Simone G., Gür, E. Ravza, Usukhbayar, Batchimeg, Salazar, Mirian Angulo, Hentges, Lance D., Mickute, Gerda, Clark, Kevin, Sopp, Paul, Davies, James O.J., Hughes, Jim R., Vyas, Paresh

Source: In Cell Stem Cell 4 May 2023 30(5):722-740

A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression

Authors: Badat, Mohsin, Davies, James O.J., Fisher, Christopher A., Downes, Damien J., Rose, Anna, Glenthøj, Andreas B., van Beers, Eduard J., Harteveld, Cornelis L., Higgs, Douglas R.

Source: Blood. 137(4):572-575

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183212353.0x000001&indx=1&recIds=ETOCvdc_100183212353.0x000001

Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder

Authors: Long, Hannah K., Osterwalder, Marco, Welsh, Ian C., Hansen, Karissa, Davies, James O.J., Liu, Yiran E., Koska, Mervenaz, Adams, Alexander T., Aho, Robert, Arora, Neha, Ikeda, Kazuya, Williams, Ruth M., Sauka-Spengler, Tatjana, Porteus, Matthew H., Mohun, Tim, Dickel, Diane E., Swigut, Tomek, Hughes, Jim R., Higgs, Douglas R., Visel, Axel, Selleri, Licia, Wysocka, Joanna

Source: In Cell Stem Cell 5 November 2020 27(5):765-783

MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation

Authors: Godfrey, Laura, Kerry, Jon, Thorne, Ross, Repapi, Emmanouela, Davies, James O.J., Tapia, Marta, Ballabio, Erica, Hughes, Jim R., Geng, Huimin, Konopleva, Marina, Milne, Thomas A.

Source: In Experimental Hematology March 2017 47:64-75

Opportunities and limitations of natural killer cells as adoptive therapy for malignant disease

Authors: Davies, James O.J., Stringaris, Kate, Barrett, A. John, Rezvani, Katayoun

Source: In Cytotherapy November 2014 16(11):1453-1466

Single-cell analysis of bone marrow–derived CD34+ cells from children with sickle cell disease and thalassemia

Authors: Hua, Peng ^{1, 2}, Roy, Noemi ^{3, 4, *}, de la Fuente, Josu ^{5, *}, Wang, Guanlin ¹, Thongjuea, Supat ¹, Clark, Kevin ¹, Roy, Anindita ⁶, Psaila, Bethan ^{1, 3, 4}, Ashley, Neil ¹, Harrington, Yvonne ⁵, Nerlov, Claus ¹, Watt, Suzanne M. ², Roberts, Irene ^{1, 4, 6}, Davies, James O.J. ^{1, 3, 4}

Source: In Blood 5 December 2019 134(23):2111-2115

Genotyping of Multiple Genomic Loci with Chromatin Accessibility Profiling in Single Cells Links Clonal Hierarchy with Epigenetic Variation in Acute Myeloid Leukemia

Authors: Turkalj, Sven ^*, Jakobsen, Niels Asger ^*, Groom, Angus ^*, Metzner, Marlen ^*, Usukhbayar, Batchimeg ^*, Angulo Salazar, Mirian ^*, Clark, Kevin ^*, Gür, E. Ravza ^*, Hentges, Lance D. ^*, Sopp, Paul ^*, Davies, James O.J. ^*, Hughes, Jim R. ^*, Vyas, Paresh

Source: In Blood 15 November 2022 140 Supplement 1:1193-1194

IRX3 Oncogene Activation in T-ALL through Enhancer Hijacking Caused By fto Intron 8 Deletions

Authors: Rahman, Sunniyat ^*, Farah, Nadine ^*, Demeulemeester, Jonas ^*, R Costa, Joana ^*, Bloye, Gianna ^*, O'Connor, David ^*, Pocock, Rachael ^*, Turna, Adam ^*, Lee, SooWah ^*, Fielding, Adele K., Roels, Juliette ^*, Dawidowska, Małgorzata ^*, Van Vlierberghe, Pieter, Hadjur, Suzana ^*, Gutierrez, Alejandro, Kelliher, Michelle A, Riva, Simone ^*, Hughes, Jim R. ^*, Davies, James O.J. ^*, Van Loo, Peter ^*, Dawson, Mark A., Mansour, Marc R. ^*

Source: In Blood 15 November 2022 140 Supplement 1:1009-1010

An Ancient Transcriptional Hub Couples Developmentally Regulated Gene Expression with Metabolism during Erythropoiesis

Authors: Preston, Alexandra E. ^*, Frost, Joe N. ^*, Badat, Mohsin ^*, Armitage, Andrew E. ^*, Wideman, Sarah ^*, Teh, Megan ^*, Norfo, Ruggiero ^*, Roy, Noémi, Davies, James O.J. ^*, Beagrie, Robert ^*, Higgs, Douglas R., Drakesmith, Hal ^*

Source: In Blood 15 November 2022 140 Supplement 1:4-5

Unlinking an lncRNA from Its Associated cis Element

Authors: Paralkar, Vikram R., Taborda, Cristian C., Huang, Peng, Yao, Yu, Kossenkov, Andrew V., Prasad, Rishi, Luan, Jing, Davies, James O.J., Hughes, Jim R., Hardison, Ross C., Blobel, Gerd A., Weiss, Mitchell J.

Source: In Molecular Cell 7 April 2016 62(1):104-110

Oral C-4 plastic explosive in humans - A case series.

Authors: Davies, James O.J.¹ (AUTHOR), Roberts, Darren M.^1,2 (AUTHOR) Darren.Roberts@anu.edu.au, Hittarage, Ariyasena³ (AUTHOR), Buckley, Nick A.⁴ (AUTHOR)

Source: Clinical Toxicology (15563650). 2007, Vol. 45 Issue 5, p454-457. 4p. 1 Diagram, 1 Chart.

Subject Terms: *EXPLOSIVES, *SPASMS, *POISONING, *MILITARY personnel, *BENZODIAZEPINES

Geographic Terms: SRI Lanka

Expression of the Human Alpha-Globin Cluster in the Absence of the Major Regulatory Element Mcs-R2

Authors: Badat, Mohsin ^*, Davies, James O.J. ^*, van Beers, Eduard J. ^*, Harteveld, Cornelis ^*, Downes, Damien ^*, Higgs, Douglas R. ^*

Source: In Blood 29 November 2018 132 Supplement 1:3632-3632

Single-cell analysis of bone marrow–derived CD34+cells from children with sickle cell disease and thalassemia

Authors: Hua, Peng, Roy, Noemi, de la Fuente, Josu, Wang, Guanlin, Thongjuea, Supat, Clark, Kevin, Roy, Anindita, Psaila, Bethan, Ashley, Neil, Harrington, Yvonne, Nerlov, Claus, Watt, Suzanne M., Roberts, Irene, Davies, James O.J.

Source: Blood; December 2019, Vol. 134 Issue: 23 p2111-2115, 5p

Comparison of Fetal and Adult Erythroid Chromosomal Architectures Identifies a Novel Fetal Hemoglobin Regulatory Region

Authors: Huang, Peng ^*, Keller, Cheryl A. ^*, Giardine, Belinda ^*, Davies, James O.J. ^*, Hughes, Jim R. ^*, Hardison, Ross C ^*, Blobel, Gerd

Source: In Blood 8 December 2017 130 Supplement 1:774-774

IRX3Oncogene Activation in T-ALL through Enhancer Hijacking Caused By ftoIntron 8 Deletions

Authors: Rahman, Sunniyat, Farah, Nadine, Demeulemeester, Jonas, R Costa, Joana, Bloye, Gianna, O'Connor, David, Pocock, Rachael, Turna, Adam, Lee, SooWah, Fielding, Adele K., Roels, Juliette, Dawidowska, Małgorzata, Van Vlierberghe, Pieter, Hadjur, Suzana, Gutierrez, Alejandro, Kelliher, Michelle A, Riva, Simone, Hughes, Jim R., Davies, James O.J., Van Loo, Peter, Dawson, Mark A., Mansour, Marc R.

Source: Blood; November 2022, Vol. 140 Issue: 1, Number 1 Supplement 1 p1009-1010, 2p