Sin Nombre Virus as Unlikely Reverse Zoonotic Threat

Authors: Jérémie Prévost, Nikesh Tailor, Anders Leung, Bryce Warner, David Safronetz

Source: Emerging Infectious Diseases, Vol 31, Iss 2, Pp 385-388 (2025)

Subject Terms: Hantavirus, Sin Nombre virus, zoonotic disease, rodentborne pathogens, zoonoses, viruses, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/31/2/24-1532_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/213df24d436f40628c164fe00e5c32ae

Current perspectives on vaccines and therapeutics for Lassa Fever

Authors: Bryce M. Warner, David Safronetz, Derek R. Stein

Source: Virology Journal, Vol 21, Iss 1, Pp 1-18 (2024)

Subject Terms: Lassa virus, Lassa fever, Vaccines, Therapeutics, Antivirals, Animal models, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1743-422X

Access URL: https://doaj.org/article/cb04721c5423490fb16b78e5f58570c3

Lipid nanoparticle encapsulation of a Delta spike-CD40L DNA vaccine improves effectiveness against Omicron challenge in Syrian hamsters

Authors: Levi Tamming, Diana Duque, Anh Tran, Casey Lansdell, Grant Frahm, Jianguo Wu, Emily E.F. Fekete, Marybeth Creskey, Sathya N. Thulasi Raman, Emmanuel Laryea, Wanyue Zhang, Annabelle Pfeifle, Caroline Gravel, Andrew Stalker, Anwar M. Hashem, Wangxue Chen, Matthew Stuible, Yves Durocher, David Safronetz, Jingxin Cao, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Xu Zhang, Michael J.W. Johnston, Xuguang Li

Source: Molecular Therapy: Methods & Clinical Development, Vol 33, Iss 1, Pp 101388- (2025)

Subject Terms: Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050124002043; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/e70f10219c4c423f87e16236b52365bb

Dissecting immunological mechanisms underlying influenza viral nucleoprotein-induced mucosal immunity against diverse viral strains

Authors: Wanyue Zhang, Angela Sloan, Jérémie Prévost, Levi Tamming, Sathya Raman, Annabelle Pfeifle, Caroline Gravel, Wangxue Chen, Anwar M. Hashem, Jianguo Wu, Jingxin Cao, Michael J. W. Johnston, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Darwyn Kobasa, David Safronetz, Xuguang Li

Source: Emerging Microbes and Infections, Vol 13, Iss 1 (2024)

Subject Terms: Influenza, nucleoprotein, universal vaccine, H5N1, intranasal, intramuscular, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/af91b9f97e864ad2ba7ba06b0cb566c9

Protective Efficacy of Lyophilized Vesicular Stomatitis Virus–Based Vaccines in Animal Model

Authors: Abd’jeleel Salawudeen, Geoff Soule, Nikesh Tailor, Levi Klassen, Jonathan Audet, Angela Sloan, Yvon Deschambault, David Safronetz

Source: Emerging Infectious Diseases, Vol 30, Iss 5, Pp 1004-1008 (2024)

Subject Terms: vesicular stomatitis virus, vaccines, Ebola virus, Lassa virus, glycoproteins, lyophilized, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/30/5/23-1248_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/e9d4dcae17374f0cbb3dff803874c7ff

Characterizing changes in transcriptome and kinome responses in testicular cells during infection by Ebola virus

Authors: Andrew L. Webb, Brayden G. Schindell, Geoff Soule, Abu B. Siddik, Bernard Abrenica, Harram Memon, Ruey-Chyi Su, David Safronetz, Jason Kindrachuk

Source: npj Viruses, Vol 2, Iss 1, Pp 1-14 (2024)

Subject Terms: Infectious and parasitic diseases, RC109-216, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2948-1767

Access URL: https://doaj.org/article/f42f61e661034cfcb46478bbba1b09c9

The rVSV-EBOV vaccine provides limited cross-protection against Sudan virus in guinea pigs

Authors: Wenguang Cao, Shihua He, Guodong Liu, Helene Schulz, Karla Emeterio, Michael Chan, Kevin Tierney, Kim Azaransky, Geoff Soule, Nikesh Tailor, Abdjeleel Salawudeen, Rick Nichols, Joan Fusco, David Safronetz, Logan Banadyga

Source: npj Vaccines, Vol 8, Iss 1, Pp 1-9 (2023)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2059-0105

Access URL: https://doaj.org/article/085daf7c13654dfeb1807e18d2a02067

Bivalent vaccines effectively protect mice against influenza A and respiratory syncytial viruses

Authors: Sathya N. Thulasi Raman, Adrian Zetner, Anwar M. Hashem, Devina Patel, Jianguo Wu, Caroline Gravel, Jun Gao, Wanyue Zhang, Annabelle Pfeifle, Levi Tamming, Karan Parikh, Jingxin Cao, Roger Tam, David Safronetz, Wangxue Chen, Michael J.W. Johnston, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Gary Van Domselaar, Xuguang Li

Source: Emerging Microbes and Infections, Vol 12, Iss 1 (2023)

Subject Terms: Adenovirus, influenza, RSV, pre-fusion stabilized F, HA-stem, RSV T-cell epitopes, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/067d067bb5254d068855c61eab6f8a16

Mucosal Vaccination with a Newcastle Disease Virus-Vectored Vaccine Reduces Viral Loads in SARS-CoV-2-Infected Cynomolgus Macaques

Authors: Bryce M. Warner, Mable Chan, Nikesh Tailor, Robert Vendramelli, Jonathan Audet, Courtney Meilleur, Thang Truong, Lauren Garnett, Marnie Willman, Geoff Soule, Kevin Tierney, Alixandra Albietz, Estella Moffat, Rick Higgins, Lisa A. Santry, Alexander Leacy, Phuc H. Pham, Jacob G. E. Yates, Yanlong Pei, David Safronetz, James E. Strong, Leonardo Susta, Carissa Embury-Hyatt, Sarah K. Wootton, Darwyn Kobasa

Source: Vaccines, Vol 12, Iss 4, p 404 (2024)

Subject Terms: Newcastle disease virus, SARS-CoV-2, COVID-19, vaccine, cynomolgus macaque, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/4/404; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/5e4cccc3f31e4e15bd81f344156fe762

Experimental Infection of North American Deer Mice with Clade I and II Monkeypox Virus Isolates

Authors: Yvon Deschambault, Levi Klassen, Geoff Soule, Kevin Tierney, Kimberly Azaransky, Angela Sloan, David Safronetz

Source: Emerging Infectious Diseases, Vol 29, Iss 4, Pp 858-860 (2023)

Subject Terms: mpox, monkeypox, MPXV, viruses, deer mouse, experimental infection, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/29/4/22-1594_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/a7969eafb16043539a537ab54a5124a6

AAV-monoclonal antibody expression protects mice from Ebola virus without impeding the endogenous antibody response to heterologous challenge

Authors: Laura P. van Lieshout, Amira D. Rghei, Wenguang Cao, Shihua He, Geoff Soule, Wenjun Zhu, Sylvia P. Thomas, Debra Sorensen, Kathy Frost, Kevin Tierney, Brad Thompson, Stephanie Booth, David Safronetz, Raveendra R. Kulkarni, Byram W. Bridle, Xiangguo Qiu, Logan Banadyga, Sarah K. Wootton

Source: Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 505-518 (2022)

Subject Terms: adeno-associated virus (AAV), Ebola, vectored immunoprophylaxis, immunotherapy, monoclonal antibody, AAV6.2FF, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122001139; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/50cc389f7095494bba9d58a113335768

Experimental Infection of Peromyscus Species Rodents with Sin Nombre Virus

Authors: Kaye Quizon, Kimberly Holloway, Mahmood Iranpour, Bryce M. Warner, Yvon Deschambault, Geoff Soule, Kevin Tierney, Darwyn Kobasa, Angela Sloan, David Safronetz

Source: Emerging Infectious Diseases, Vol 28, Iss 9, Pp 1882-1885 (2022)

Subject Terms: Sin Nombre virus, viruses, Peromyscus, Peromyscus leucopus, Peromyscus maniculatus, rodents, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/28/9/22-0509_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/62cfceb8c9194741a1039bd12835caeb

Bivalent VSV Vectors Mediate Rapid and Potent Protection from Andes Virus Challenge in Hamsters

Authors: Joshua Marceau, David Safronetz, Cynthia Martellaro, Andrea Marzi, Kyle Rosenke, Heinz Feldmann

Source: Viruses, Vol 16, Iss 2, p 279 (2024)

Subject Terms: Orthohantavirus, Andes virus, VSV, vaccine, Syrian hamster, emergency vaccination, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/2/279; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/51d114e90f5e4a1abcf81c7b40f785c0

The Nucleocapsid Proteins of SARS-CoV-2 and Its Close Relative Bat Coronavirus RaTG13 Are Capable of Inhibiting PKR- and RNase L-Mediated Antiviral Pathways

Authors: Kyle LeBlanc, Jessie Lynch, Christine Layne, Robert Vendramelli, Angela Sloan, Nikesh Tailor, Yvon Deschambault, Fushun Zhang, Darwyn Kobasa, David Safronetz, Yan Xiang, Jingxin Cao

Source: Microbiology Spectrum, Vol 11, Iss 3 (2023)

Subject Terms: G3BP1, PKR, RNase L, RaTG13, SARS-CoV-2 nucleocapsid, double-stranded RNA virus, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/73fcb0d71715445dbe5f0a8ebe2b1962

Universal antibody targeting the highly conserved fusion peptide provides cross-protection in mice

Authors: Abenaya Muralidharan, Caroline Gravel, Greg Harris, Anwar M. Hashem, Wanyue Zhang, David Safronetz, Gary Van Domselaar, Florian Krammer, Simon Sauve, Michael Rosu-Myles, Lisheng Wang, Wangxue Chen, Xuguang Li

Source: Human Vaccines & Immunotherapeutics, Vol 18, Iss 5 (2022)

Subject Terms: influenza, universal antibody, uni-1, antibody-dependent cellular cytotoxicity (adcc), cross-protection, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/ccd578b18a514979825967ec1ed675d0

An introduction to the Marburg virus vaccine consortium, MARVAC

Authors: Robert W. Cross, Ira M. Longini, Stephan Becker, Karin Bok, David Boucher, Miles W. Carroll, Janet V. Díaz, William E. Dowling, Ruxandra Draghia-Akli, James T. Duworko, John M. Dye, Michael A. Egan, Patricia Fast, Amy Finan, Courtney Finch, Thomas R. Fleming, Joan Fusco, Thomas W. Geisbert, Anthony Griffiths, Stephan Günther, Lisa E. Hensley, Anna Honko, Ruth Hunegnaw, Jocelyn Jakubik, Julie Ledgerwood, Kerstin Luhn, Demetrius Matassov, Jeffrey Meshulam, Emily V. Nelson, Christopher L. Parks, Roxana Rustomjee, David Safronetz, Lauren M. Schwartz, Dean Smith, Paul Smock, Ydrissa Sow, Christina F. Spiropoulou, Nancy J. Sullivan, Kelly L. Warfield, Daniel Wolfe, Courtney Woolsey, Roland Zahn, Ana María Henao-Restrepo, César Muñoz-Fontela, Andrea Marzi

Source: PLoS Pathogens, Vol 18, Iss 10 (2022)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560149/?tool=EBI; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/eb16d630ec60444cb74dc537f414a98d

Polyclonal alpaca antibodies protect against hantavirus pulmonary syndrome in a lethal Syrian hamster model

Authors: Patrycja Sroga, Angela Sloan, Bryce M. Warner, Kevin Tierney, Jocelyne Lew, Guodong Liu, Michael Chan, Yvon Deschambault, Derek R. Stein, Geoff Soule, Logan Banadyga, Darryl Falzarano, David Safronetz

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/9c32e3c2b2f64cb28285301295ae86fb

Ebola Virus IgG Seroprevalence in Southern Mali

Authors: Sidy Bane, Kyle Rosenke, Ousmane Maiga, Friederike Feldmann, Kimberly Meade-White, Julie Callison, David Safronetz, Nafomon Sogoba, Heinz Feldmann

Source: Emerging Infectious Diseases, Vol 27, Iss 6, Pp 1681-1684 (2021)

Subject Terms: Ebola virus, ebolaviruses, filoviruses, serology, viruses, zoonoses, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/27/6/20-3510_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/4698ea7eb2e341e3ae9540af0e8c052b

SARS-CoV-2 infection and transmission in the North American deer mouse

Authors: Bryan D. Griffin, Mable Chan, Nikesh Tailor, Emelissa J. Mendoza, Anders Leung, Bryce M. Warner, Ana T. Duggan, Estella Moffat, Shihua He, Lauren Garnett, Kaylie N. Tran, Logan Banadyga, Alixandra Albietz, Kevin Tierney, Jonathan Audet, Alexander Bello, Robert Vendramelli, Amrit S. Boese, Lisa Fernando, L. Robbin Lindsay, Claire M. Jardine, Heidi Wood, Guillaume Poliquin, James E. Strong, Michael Drebot, David Safronetz, Carissa Embury-Hyatt, Darwyn Kobasa

Source: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/9da1c4d9e45e4f76a8779fa6d68d2b3b

Japanese encephalitis virus persists in the human reproductive epithelium and porcine reproductive tissues.

Authors: Subash Chapagain, Prince Pal Singh, Khanh Le, David Safronetz, Heidi Wood, Uladzimir Karniychuk

Source: PLoS Neglected Tropical Diseases, Vol 16, Iss 7, p e0010656 (2022)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/2d32aa86bb2a440d9e4bf5ad25a774a3