Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent multiple sclerosis risk

Authors: Lawrence T. C. Ong, Stephen D. Schibeci, Nicole L. Fewings, David R. Booth, Grant P. Parnell

Source: Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-12 (2021)

Subject Terms: DNA methylation, Calcitriol, Epigenetics, Vitamin D, Myeloid, VDR binding site, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-8935

Access URL: https://doaj.org/article/558e1c80adae4c4ca479212c2e038d5d

Gender and the Sex Hormone Estradiol Affect Multiple Sclerosis Risk Gene Expression in Epstein-Barr Virus-Infected B Cells

Authors: Jeremy T. Keane, Ali Afrasiabi, Stephen D. Schibeci, Nicole Fewings, Grant P. Parnell, Sanjay Swaminathan, David R. Booth

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: Epstein-Barr virus (EBV), multiple sclerosis, sex-bias, eQTL, estrogen, estradiol, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.732694/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/52f82a24ea514b87ab607ed82bc1f99f

Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility

Authors: Ali Afrasiabi, Grant P. Parnell, Nicole Fewings, Stephen D. Schibeci, Monica A. Basuki, Ramya Chandramohan, Yuan Zhou, Bruce Taylor, David A. Brown, Sanjay Swaminathan, Fiona C. McKay, Graeme J. Stewart, David R. Booth

Source: Genome Medicine, Vol 11, Iss 1, Pp 1-13 (2019)

Subject Terms: Multiple sclerosis, Genetics, Epstein-Barr virus, Risk genes, Expression quantitative trait loci, miRNA, Medicine, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13073-019-0640-z; https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/6dd9c48e50fe4d28bccc98bc12d1082e

Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome

Authors: Stephanie Trend, Anderson P. Jones, Lilian Cha, Scott N. Byrne, Sian Geldenhuys, Marzena J. Fabis-Pedrini, William M. Carroll, Judith M. Cole, David R. Booth, Robyn M. Lucas, Allan G. Kermode, Martyn A. French, Prue H. Hart

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: clinically isolated syndrome, multiple sclerosis, immunoglobulin, antibody, biomarkers, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.01590/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/32efa4670cdb4b5281441036fe52b8e3

BAFF is a Biological Response Marker to IFN-β Treatment in Multiple Sclerosis.

Authors: Kaushal S. Gandhi, Fiona C. McKay, Stephen D. Schibeci, Jonathan W. Arthur, Rob N. Heard, Graeme J. Stewart, David R. Booth

Source: Journal of Interferon & Cytokine Research; Sep2008, Vol. 28 Issue 9, p529-540, 12p

Subject Terms: MULTIPLE sclerosis treatment, BIOMARKERS, INTERFERONS, GENE expression, IMMUNOGLOBULINS, AUTOIMMUNE disease treatment

Hepatitis C Virus Driven AXL Expression Suppresses the Hepatic Type I Interferon Response.

Authors: Scott A Read, Enoch S Tay, Mahsa Shahidi, Kate S O'Connor, David R Booth, Jacob George, Mark W Douglas

Source: PLoS ONE, Vol 10, Iss 8, p e0136227 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4551482?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/08fc8a2c46fb49bf9fb285b8a0859a8e

IL7Rα expression and upregulation by IFNβ in dendritic cell subsets is haplotype-dependent.

Authors: Fiona C McKay, Edwin Hoe, Grant Parnell, Prudence Gatt, Stephen D Schibeci, Graeme J Stewart, David R Booth

Source: PLoS ONE, Vol 8, Iss 10, p e77508 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3797747?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/31ed427fd32c4fc3be012982a02f12e8

IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional study.

Authors: Vijayaprakash Suppiah, Silvana Gaudieri, Nicola J Armstrong, Kate S O'Connor, Thomas Berg, Martin Weltman, Maria Lorena Abate, Ulrich Spengler, Margaret Bassendine, Gregory J Dore, William L Irving, Elizabeth Powell, Margaret Hellard, Stephen Riordan, Gail Matthews, David Sheridan, Jacob Nattermann, Antonina Smedile, Tobias Müller, Emma Hammond, David Dunn, Francesco Negro, Pierre-Yves Bochud, Simon Mallal, Golo Ahlenstiel, Graeme J Stewart, Jacob George, David R Booth, International Hepatitis C Genetics Consortium (IHCGC)

Source: PLoS Medicine, Vol 8, Iss 9, p e1001092 (2011)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21931540/?tool=EBI; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/35e1fae1f2ff4e0fbdcb58e851dcbeeb

A transcription factor map as revealed by a genome-wide gene expression analysis of whole-blood mRNA transcriptome in multiple sclerosis.

Authors: Carlos Riveros, Drew Mellor, Kaushal S Gandhi, Fiona C McKay, Mathew B Cox, Regina Berretta, S Yahya Vaezpour, Mario Inostroza-Ponta, Simon A Broadley, Robert N Heard, Stephen Vucic, Graeme J Stewart, David W Williams, Rodney J Scott, Jeanette Lechner-Scott, David R Booth, Pablo Moscato, ANZgene Multiple Sclerosis Genetics Consortium

Source: PLoS ONE, Vol 5, Iss 12, p e14176 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21152067/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/57cf07fc99e548b88dcd763073a08da1

A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis.

Authors: Judith Field, Sharon R Browning, Laura J Johnson, Patrick Danoy, Michael D Varney, Brian D Tait, Kaushal S Gandhi, Jac C Charlesworth, Robert N Heard, Australia and New Zealand Multiple Sclerosis Genetics Consortium, Graeme J Stewart, Trevor J Kilpatrick, Simon J Foote, Melanie Bahlo, Helmut Butzkueven, James Wiley, David R Booth, Bruce V Taylor, Matthew A Brown, Justin P Rubio, Jim Stankovich

Source: PLoS ONE, Vol 5, Iss 10, p e13454 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2964313?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/666c12ee17314e0d830ff51e46de6064

MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood.

Authors: Mathew B Cox, Murray J Cairns, Kaushal S Gandhi, Adam P Carroll, Sophia Moscovis, Graeme J Stewart, Simon Broadley, Rodney J Scott, David R Booth, Jeannette Lechner-Scott, ANZgene Multiple Sclerosis Genetics Consortium

Source: PLoS ONE, Vol 5, Iss 8, p e12132 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2920328?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/08421e7245d1407d9ac2d8dacc401bf5

Novel approaches to detect serum biomarkers for clinical response to interferon-beta treatment in multiple sclerosis.

Authors: Kaushal S Gandhi, Fiona C McKay, Eve Diefenbach, Ben Crossett, Stephen D Schibeci, Robert N Heard, Graeme J Stewart, David R Booth, Jonathan W Arthur

Source: PLoS ONE, Vol 5, Iss 5, p e10484 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2864746?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/8c6ea329e8b54c66ae614ed5dc5195ca